Oncogenes, onco-suppressors, carcinogenesis and oral cancer.

Abstract:

:The regulation of cell growth is fundamental to the maintenance of health: disturbed regulation can result in neoplasia. Genes in normal cells (protooncogenes) code for proteins involved in the regulation of cell growth and differentiation; abnormalities in these genes (oncogenes) or their expression are often involved in the development of cancer. This paper summarises the essentials of the complex cell growth regulatory mechanisms, their genetic control, and their disturbances in neoplasia, emphasising the role of cancer-promoting (oncogenes) and suppressing genes (onco-suppressors or anti-oncogenes), especially in relation to oral carcinoma, and discusses the possible role of viruses as one cause of neoplasia.

journal_name

Br Dent J

journal_title

British dental journal

authors

Scully C

doi

10.1038/sj.bdj.4807936

subject

Has Abstract

pub_date

1992-07-25 00:00:00

pages

53-9

issue

2

eissn

0007-0610

issn

1476-5373

pii

4807936

journal_volume

173

pub_type

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    doi:10.1038/sj.bdj.2009.727

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  • Preparedness of dental graduates for foundation training: a qualitative study.

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    pub_type: 杂志文章

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