Estimating with confidence the risk of rare adverse events, including those with observed rates of zero.

abstract：BACKGROUND:A difficult neuraxial block (DNB) may be associated with complications. The aims of this study were to estimate the prevalence of DNB, assess patient-related and organizational factors associated with DNB, and evaluate the diagnostic accuracy of an accumulated risk score for predicting DNB. METHODS:A consec...

journal_title：Regional anesthesia and pain medicine

authors： Stendell L,Lundstrøm LH,Wetterslev J,Itenov TS,Rosenstock CV

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:This report describes the effects of ganglionic local opioid application (GLOA) in patients with chronic headache and persistent idiopathic facial pain. CASE REPORT:We present 2 patients with chronic headaches and 1 patient with persistent idiopathic facial pain who were refractory to medical treatment. Thes...

journal_title：Regional anesthesia and pain medicine

authors： Harris CL,Hamid B,Rosenquist RW,Schultz-Stubner SH

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Because of the uncertainty and limitations in available randomized controlled trials, we performed an analysis of the Medicare claims database to determine whether an association exists between postoperative epidural analgesia and mortality. METHODS:A 5% nationally random sample of Medicare beneficiaries fr...

journal_title：Regional anesthesia and pain medicine

authors： Wu CL,Hurley RW,Anderson GF,Herbert R,Rowlingson AJ,Fleisher LA

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Success in performing ultrasound-guided peripheral nerve blockade (PNB) demands sound knowledge of sonoanatomy, good scanning techniques, and proper hand-eye coordination. The objectives of our study were to evaluate whether simulator training aids success of novice operators in ultrasound-gui...

journal_title：Regional anesthesia and pain medicine

authors： Niazi AU,Haldipur N,Prasad AG,Chan VW

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The posterior approach to performing a continuous brachial plexus block at the level of the nerve roots has been described using traditional superficial landmarks. We describe an ultrasound-guided approach for the placement of a continuous interscalene brachial plexus catheter at the level of ...

journal_title：Regional anesthesia and pain medicine

authors： Antonakakis JG,Sites BD,Shiffrin J

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:This prospective, randomized, double-blind study compares the efficacy of two spinal needles in terms of their performance characteristics and associated perioperative complaints in young patients. METHODS:ASA I and II patients aged from 20 to 40 years undergoing lower limb orthopedic surgery...

journal_title：Regional anesthesia and pain medicine

authors： De Andrés J,Valia JC,Errando C,Rico G,Lopez-Alarcon MD

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Detailed description of the tasks anesthetists undertake during the performance of a complex procedure, such as ultrasound-guided peripheral nerve blockade, allows elements that are vulnerable to human error to be identified. We have applied 3 task analysis tools to one such procedure, namely, ultrasound-gui...

journal_title：Regional anesthesia and pain medicine

authors： O'Sullivan O,Aboulafia A,Iohom G,O'Donnell BD,Shorten GD

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to compare the potency of bupivacaine, ropivacaine, and levobupivacaine in an equal dose and concentration for sympathetic block. METHODS:We measured mean arterial pressure, heart rate (HR), and right and left brachial artery blood flow (BABF) before and after cervic...

journal_title：Regional anesthesia and pain medicine

authors： Hashimoto T,Iwasaki T,Takahashi Y,Kimura Y,Nagao M,Yamaguchi S,Hamaguchi S,Kitajima T

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Ultrasound (US) guidance, in some instances, can increase the success rate and reduce the onset and procedure times for peripheral nerve blockade compared with traditional nerve localization techniques. The presumptive mechanism for these benefits is the ability to accurately inject local anesthetic circumfe...

journal_title：Regional anesthesia and pain medicine

authors： Brull R,Macfarlane AJ,Parrington SJ,Koshkin A,Chan VW

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Hematoma is typically cited as one mechanism of nerve injury following axillary block. However, documented cases of this are lacking. METHODS:A healthy 38-year-old man was scheduled for surgical removal of a tumor of the hand. A transarterial axillary block was performed with a 22-gauge short...

journal_title：Regional anesthesia and pain medicine

authors： Ben-David B,Stahl S

更新日期：1999-05-01 00:00:00

abstract：:As anesthesiologists and acute pain medicine specialists, we will care for patients in the perioperative period who use cannabinoids for chronic pain and/or marijuana recreationally. We will have to address difficult questions from patients regarding the potential applications for cannabinoids in acute pain management...

journal_title：Regional anesthesia and pain medicine

authors： Meeker JD,Ayrian E,Mariano ER

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:0.1% bupivacaine for obstetric epidural analgesia is given by infusion, using a loading dose of a higher concentration alone or in combination with opioid analgesics. A single dose of 0.1% without any additive for relief of first-stage labor pain has not yet been documented. METHODS:Fifty-eig...

journal_title：Regional anesthesia and pain medicine

authors： Christiaens F,Verborgh C,Dierick A,Camu F

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Pregabalin is often used as a perioperative analgesic adjunct; some studies show benefit, but others do not. Adverse effects, such as confusion and sedation, have been attributed to perioperative use of pregabalin. We tested the hypothesis that pregabalin, when used as part of a multimodal ana...

journal_title：Regional anesthesia and pain medicine

authors： Yadeau JT,Paroli L,Kahn RL,Jules-Elysee KM,Lasala VR,Liu SS,Lin E,Powell K,Buschiazzo VL,Wukovits B,Roberts MM,Levine DS

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The benefit of adding sciatic nerve block (SNB) to femoral nerve block to improve analgesia after total knee arthroplasty (TKA) is uncertain. We hypothesized that the effective duration of single-injection SNB is too short to improve postoperative analgesia and that this contributes to conflic...

journal_title：Regional anesthesia and pain medicine

authors： Sato K,Adachi T,Shirai N,Naoi N

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:No studies have examined the long-term benefits of regional anesthesia (RA) for pain management after combat-related injury. The objective of this prospective cohort study was to examine the relationship between RA administration and patient-reported pain-related outcomes among Operation Enduring Freedom (OE...

journal_title：Regional anesthesia and pain medicine

authors： Gallagher RM,Polomano RC,Giordano NA,Farrar JT,Guo W,Taylor L,Oslin D,Goff BJ,Buckenmaier CC

更新日期：2019-09-27 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Perioperative systemic lidocaine provides postoperative analgesia, decreases opioid consumption, and facilitates rehabilitation in abdominal surgery. We hypothesized that systemic lidocaine has analgesic effects in women undergoing day-case laparoscopic sterilization. METHODS:Eighty women wer...

journal_title：Regional anesthesia and pain medicine

authors： Dewinter GB,Teunkens A,Vermeulen K,Al Tmimi L,Van de Velde M,Rex S

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:We present a case of reappearance of spinal anesthesia despite the use of plain (isobaric) lidocaine and without an associated cough or Valsalva maneuver. CASE REPORT:A 66-year-old man had spinal anesthesia for knee arthroscopy. Two hours after the induction of spinal anesthesia and after the patient's motor...

journal_title：Regional anesthesia and pain medicine

authors： Deleon AM,Benzon HT,Eisenman TS,Doty RA Jr,Newell B,McLaughlin K

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:This prospective, randomized, double-blind study compared the effects of the ultrasound-guided popliteal sciatic nerve block performed by either intraneural or subparaneural approach followed by an electrophysiological evaluation. We hypothesized that intraneural injection provides a faster on...

journal_title：Regional anesthesia and pain medicine

authors： Cappelleri G,Cedrati VL,Fedele LL,Gemma M,Camici L,Loiero M,Gallazzi MB,Cornaggia G

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Complications resulting from vascular penetration during nerve blocks are rare but potentially devastating events that can occur despite meticulous technique. In this in vivo human pilot study, we investigated the potential for detecting vascular penetration with optical reflectance spectrosco...

journal_title：Regional anesthesia and pain medicine

authors： Balthasar A,Desjardins AE,van der Voort M,Lucassen GW,Roggeveen S,Wang K,Bierhoff W,Kessels AG,Sommer M,van Kleef M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We sought to describe a case of an epidural hematoma after a cervical interlaminar epidural steroid injection (ILESI) performed using contralateral oblique view. We also discuss factors that could have placed this patient at increased risk, including concurrent use of omega-3 fatty acids and n...

journal_title：Regional anesthesia and pain medicine

authors： Beasley D,Goree JH

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Cervical medial branch blocks are used to treat patients with chronic neck pain. The aim of this study was to clarify the anatomical aspects of the cervical medial branches to improve the accuracy and safety of radiofrequency denervation. METHODS:Twenty cervical specimens were harvested from ...

journal_title：Regional anesthesia and pain medicine

authors： Kweon TD,Kim JY,Lee HY,Kim MH,Lee YW

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Several studies have evaluated the impact of preoperative depression on outcomes following total joint arthroplasty (TJA), however few have studied new-onset depression or anxiety after TJA. We aimed to identify the incidence of and risk factors for new-onset depression/anxiety after TJA, specifically focusi...

journal_title：Regional anesthesia and pain medicine

authors： Wilson L,Bekeris J,Fiasconaro M,Liu J,Poeran J,Kim DH,Gonzalez Della Valle A,Memtsoudis SG

更新日期：2019-09-16 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Peripheral nerve blocks can be successfully utilized in infants for neurosurgical procedures. Our objective was utilizing a series of peripheral nerve blocks for a neurosurgical procedure in a very low-birth-weight neonate. CASE REPORT:We report the use of supraorbital, great auricular, and g...

journal_title：Regional anesthesia and pain medicine

authors： Suresh S,Bellig G

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Prior to this investigation, there was no approach to compare both the potency of local anesthetics and their time course of action in a reproducible nociceptive system in humans. We tested whether the vascularly isolated vein segment is appropriate for such an approach. METHODS:In six health...

journal_title：Regional anesthesia and pain medicine

authors： Holthusen H,Lipfert P,Klement W

更新日期：1999-07-01 00:00:00

abstract：:Conventional opioids are widely used for acute pain management in the postoperative setting. However, a primary concern with conventional opioids is their therapeutic window-the range between doses that produce the desired therapeutic effect (analgesia) and doses that produce unwanted opioid-related adverse events (OR...

journal_title：Regional anesthesia and pain medicine

authors： Viscusi ER

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:We have investigated how the vascular components of the spine determine the resistance and capacitance of the spinal epidural space and determined the magnitude of the longitudinal pressure gradient in the space during fluid infusion. METHODS:Pigs were studied during isoflurane anesthesia. Tu...

journal_title：Regional anesthesia and pain medicine

authors： Blix EU,Buffington CW

更新日期：2009-03-01 00:00:00

abstract：INTRODUCTION:Diabetes may affect the duration of nerve block after regional anesthesia. This study aimed to compare the durations of sensory and motor block in diabetes versus non-diabetes patients after lower limb nerve block and delineate any sex-based differences in the duration of sensory and motor blocks of both d...

journal_title：Regional anesthesia and pain medicine

authors： Tang S,Wang J,Tian Y,Li X,Cui Q,Xu M,Song X,Zheng Y,Yang H,Ma C,Zhan L,Zhu C,Zhang Y,Yao M,Huang Y

更新日期：2019-07-12 00:00:00

abstract：BACKGROUND:A growing body of evidence indicates that the use of regional anesthesia offers advantages over general anesthesia, not only in terms of reducing complications but also regarding resource utilization and patient satisfaction. Because of the paucity of data on the nationwide adoption of regional anesthesia te...

journal_title：Regional anesthesia and pain medicine

authors： Cozowicz C,Poeran J,Zubizarreta N,Mazumdar M,Memtsoudis SG

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:A common analgesic technique for total knee arthroplasty (TKA) is to inject local anesthetic into the periarticular tissue during surgery, known as local infiltration analgesia (LIA). Since the solution used typically contains a large amount of local anesthetic, concerns arise about exceeding ...

journal_title：Regional anesthesia and pain medicine

authors： Koniuch KL,Buys MJ,Campbell B,Gililland JM,Pelt CE,Pace NL,Johnson KB

更新日期：2019-01-11 00:00:00

abstract：BACKGROUND:Neosaxitoxin (NeoSTX) is a potent site-1 sodium-channel blocker being developed as a local anesthetic. Doses of 100 μg have been used by local infiltration in anesthetized adult humans without adverse effect. We hypothesized that similar doses could cause significant respiratory, neuromuscular, and cardiovas...

journal_title：Regional anesthesia and pain medicine

authors： Wylie MC,Johnson VM,Carpino E,Mullen K,Hauser K,Nedder A,Kheir JN,Rodriguez-Navarro AJ,Zurakowski D,Berde CB

更新日期：2012-03-01 00:00:00