Ischemia-reperfusion injury of the liver with special reference to calcium-dependent mechanisms.

Abstract:

:Ischemia-reperfusion (I/R) injury is a complex process involving numerous intracellular signaling pathways, mediators, cells, and pathophysiological disturbances; its prevention during liver surgery is of utmost importance. In this review, we divide hepatic I/R injury into two phases, intracellular and extracellular, for a better understanding of the processes involved. Ca2+ and Ca2+-dependent reactions play an important role as a trigger in the former phase, while the subsequent generation of bioactive substances plays a predominant role in the latter phase. These findings indicate that a combination of different therapeutic approaches against Ca2+-dependent steps may help prevent I/R injury of the liver.

journal_name

Surg Today

journal_title

Surgery today

authors

Sakon M,Ariyoshi H,Umeshita K,Monden M

doi

10.1007/s595-002-8105-8

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

1-12

issue

1

eissn

0941-1291

issn

1436-2813

journal_volume

32

pub_type

杂志文章,评审
  • Long-term outcome following neoadjuvant therapy for resectable and borderline resectable pancreatic cancer compared to upfront surgery: a meta-analysis of comparative studies by intention-to-treat analysis.

    abstract::The aim of the study was to evaluate the effect of neoadjuvant therapy on long-term survival in patients with resectable and borderline resectable pancreatic cancer. A meta-analysis was conducted using the reported randomized, controlled trials and retrospective studies using an intention-to-treat analysis to compare ...

    journal_title:Surgery today

    pub_type: 杂志文章,meta分析

    doi:10.1007/s00595-019-01786-w

    authors: Unno M,Hata T,Motoi F

    更新日期:2019-04-01 00:00:00

  • Serum levels of interleukin-12 in Graves' disease and their dynamic changes after surgery.

    abstract:PURPOSE:To investigate the role of interleukin-12 (IL-12) in Graves' disease, we measured the pre- and postoperative levels of serum IL-12 in patients undergoing surgery for Graves' disease. METHODS:The subjects of this study were 73 patients with Graves' disease, admitted for surgical treatment after taking antithyro...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-005-3083-7

    authors: Murakami S,Okubo K,Tsuji Y,Sakata H,Kikuchi M,Takahashi T,Kato T,Hirayama R

    更新日期:2005-01-01 00:00:00

  • Association between incisional surgical site infection and the type of skin closure after stoma closure.

    abstract:PURPOSE:This study was performed to investigate the effect of subcuticular sutures on the incidence of incisional surgical site infection (SSI) after closure of a diverting stoma. METHODS:The study was carried out as a retrospective analysis of prospectively collected data from 51 patients who underwent closure of div...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-010-4405-y

    authors: Kobayashi S,Ito M,Sugito M,Kobayashi A,Nishizawa Y,Saito N

    更新日期:2011-07-01 00:00:00

  • The practice of breast self-examination results in the earlier detection and better clinical course of Japanese women with breast cancer.

    abstract::Using a questionnaire survey, we analyzed the relationship between the frequency of breast self-examination (BSE) and the clinical stage and course of breast cancer in Japanese patients. BSE had been performed monthly by only 5.4% of the patients (M group), occasionally by 35.4% (O group), and not at all by 59.2% (N g...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02348564

    authors: Kurebayashi J,Shimozuma K,Sonoo H

    更新日期:1994-01-01 00:00:00

  • Intraperitoneal migration of a mesh plug with a small intestinal perforation: report of a case.

    abstract::Tension-free hernia repair with a mesh plug shows a low recurrence rate, but in a very few cases it can result in new complications including mesh migration and violation of the peritoneum. This report describes the case of a 79-year-old man who had undergone an inguinal hernioplasty using a polypropylene mesh plug 2 ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-009-4107-5

    authors: Chen MJ,Tian YF

    更新日期:2010-06-01 00:00:00

  • Internal jugular vein malformation with mature adipose deposits in the mediastinum.

    abstract::Anomalies of the internal jugular vein are uncommon and not frequently experienced. Either a fusiform or saccular dilatation of the veins has been termed phlebectasia by some investigators and venous aneurysm by others. In 1928 Harris was the first to describe this condition using the term "congenital venous cyst." Re...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950050164

    authors: Sugiyama S,Murakami A,Yokokawa M,Misaki T,Wakaki K

    更新日期:1998-01-01 00:00:00

  • Fissurectomy with posterior midline sphincterotomy and anoplasty (FPSA) in the management of chronic anal fissures.

    abstract::Although lateral internal sphincterotomy is widely accepted as the treatment of choice for anal fissures, we report our experience of successfully treating 195 consecutive patients with posterior chronic anal fissures by performing fissurectomy with midline sphincterotomy and anoplasty (FPSA). The surgical technique i...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02388152

    authors: Di Castro A,Biancari F,D'Andrea V,Caviglia A

    更新日期:1997-01-01 00:00:00

  • Development of a fistula between an internal mammary artery graft and the pulmonary vasculature following coronary artery bypass grafting: report of a case.

    abstract::We report herein the rare case of a 56-year-old man who gradually developed congestive cardiac failure 6 months after undergoing coronary artery bypass grafting and was found to have a fistula between the internal mammary artery and the pulmonary artery of the upper lobe diagnosed by selective left internal mammary ar...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00311829

    authors: Imawaki S,Arioka I,Nakai M,Tsuruno Y,Takama T,Maeta H,Inagawa T

    更新日期:1995-01-01 00:00:00

  • Benefits of home parenteral nutrition before lung transplantation: report of a case.

    abstract::A 54-year-old woman, who was severely malnourished and awaiting lung transplantation for chronic respiratory failure, was given nutritional support by home parenteral nutrition (HPN). The patient's emaciated state was further compromised by the fact that she had undergone a distal gastrectomy 4 years earlier. We decid...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-004-2753-1

    authors: Inoue Y,Minami M,Mizuta T,Kimura T,Hirabayashi H,Okumura M,Ohta M,Miyoshi S,Katoh K,Hayashi Y,Matsuda H

    更新日期:2004-01-01 00:00:00

  • SOCS3 overexpression in T cells ameliorates chronic airway obstruction in a murine heterotopic tracheal transplantation model.

    abstract:PURPOSE:Suppressor of cytokine signaling-3 (SOCS3) is a negative feedback inhibitor of cytokine signaling with T-cell-mediated immunosuppressive effects on obliterative bronchiolitis (OB). In this study, we aimed to investigate the impact of T-cell-specific overexpression of SOCS3 using a murine heterotopic tracheal tr...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-018-1753-5

    authors: Mesaki K,Yamane M,Sugimoto S,Fujisawa M,Yoshimura T,Kurosaki T,Otani S,Miyoshi S,Oto T,Matsukawa A,Toyooka S

    更新日期:2019-05-01 00:00:00

  • Acinic cell carcinoma of the trachea: report of a case.

    abstract::Acinic cell carcinoma (ACC) is a very rare primary tracheal carcinoma. We report a case of primary ACC of the trachea, which represents, to the best of our knowledge, only the fifth such case ever documented. Pharyngolaryngoesophagectomy was necessary for complete resection because the tumor invaded the trachea widely...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-004-2797-2

    authors: Tsukayama S,Omura K,Kanehira E,Kawakami K,Oda M,Ohtake H,Nonomura A,Watanabe G

    更新日期:2004-01-01 00:00:00

  • The use of bioelectrical impedance analysis for monitoring body composition changes during nutritional support.

    abstract::Body composition was measured with bioelectric impedance analysis (BIA) in 30 patients with protein malnutrition following biliopancreatic diversion. Determinations were carried out prior to, during, and at the completion of intravenous nutritional support when the nutritional parameters had completely reverted to nor...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00311363

    authors: Adami GF,Marinari G,Gandolfo P,Cocchi F,Friedman D,Scopinaro N

    更新日期:1993-01-01 00:00:00

  • Surgical treatment of a cardiac papillary fibroelastoma developing from the chordae of the tricuspid valve: report of a case.

    abstract::Papillary fibroelastoma is a rare, benign cardiac tumor that can cause multiple emboli. We report herein a case of papillary fibroelastoma developing from the chordae of the tricuspid valve which was detected by echocardiography and confirmed by surgical resection. To our knowledge, this is only the fifth documented c...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950050154

    authors: Nishimura Y,Naito Y,Fujiwara K,Komai H,Noguchi Y

    更新日期:1998-01-01 00:00:00

  • Malignant glomus tumor of the stomach with multiorgan metastases: report of a case.

    abstract::This report presents the case of a 65-year-old female patient with a malignant glomus tumor of the stomach, with metastases to the kidney and brain. The clinical presentation and imaging results are discussed, and the literature on malignant glomus tumors is reviewed. ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-008-4113-z

    authors: Song SE,Lee CH,Kim KA,Lee HJ,Park CM

    更新日期:2010-07-01 00:00:00

  • Lymphoepithelial cyst of the pancreas: report of a case.

    abstract::An extremely rare case of a lymphoepithelial cyst (LEC) of the pancreas is described herein. A pancreatic cystic tumor was initially detected in a 50-year-old man at a medical checkup. On admission, his serum carbohydrate antigen (CA) 19-9 level was 8100 U/ml and a computed tomography scan revealed a well-circumscribe...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950070074

    authors: Tsuchiya Y,Suzuki S,Sakaguchi T,Kojima Y,Okamoto K,Kurachi K,Konno H,Baba S,Nakamura S

    更新日期:2000-01-01 00:00:00

  • Transanal drainage tube placement to prevent anastomotic leakage following colorectal cancer surgery with double stapling reconstruction.

    abstract:PURPOSE:Anastomotic leakage (AL) is a critical complication of colorectal cancer surgery. The transanal drainage tube (TDT) is designed to prevent AL caused by decompression and stasis at the anastomosis. We conducted this study to investigate the feasibility of using the TDT to prevent AL following double-stapling tec...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-015-1230-3

    authors: Matsuda M,Tsuruta M,Hasegawa H,Okabayashi K,Kondo T,Shimada T,Yahagi M,Yoshikawa Y,Kitagawa Y

    更新日期:2016-05-01 00:00:00

  • Multicentric occurrence of esophageal cancer after gastrectomy: a preliminary report.

    abstract::The effect of gastrectomy on the subsequent development of esophageal cancer was investigated, focusing on its multicentric occurrence. We retrospectively evaluated 28 patients who underwent subtotal esophagectomy for intrathoracic esophageal cancer between 1985 and 1999. They were divided into two groups according to...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950170067

    authors: Kitabayashi K,Nakano Y,Saito H,Ueno KI,Kita I,Takashima S,Kurose N,Nojima T

    更新日期:2001-01-01 00:00:00

  • Laparoscopic surgery for splenic injuries in the era of non-operative management: current status and future perspectives.

    abstract::The spleen is one of the organs most commonly injured by blunt abdominal trauma. It plays an important role in immune response to infections, especially those sustained by encapsulated bacteria. Nonoperative management (NOM), comprising clinical and radiological observation with or without angioembolization, is the tr...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s00595-020-02177-2

    authors: Romeo L,Bagolini F,Ferro S,Chiozza M,Marino S,Resta G,Anania G

    更新日期:2020-11-16 00:00:00

  • Salvage lymphadenectomy of the right recurrent nerve node with tracheal involvement after definitive chemoradiation therapy for esophageal squamous cell carcinoma: report of two cases.

    abstract::Thoracic esophageal cancers frequently metastasize to the right recurrent nerve nodes (RRNNs). In fact, huge RRNNs invading the trachea sometimes remain after definitive chemoradiation therapy (CRT), despite complete remission of the primary lesion. We performed salvage lymphadenectomy of a large RRNN combined with pa...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-006-3447-7

    authors: Doki Y,Yasuda T,Miyata H,Fujiwara Y,Takiguchi S,Yamasaki M,Makari Y,Matsuyama J,Masuoka T,Monden M

    更新日期:2007-01-01 00:00:00

  • Sigmoid colon cancer presenting as complete rectal prolapse: report of a case.

    abstract::We describe herein the unusual case of a 76-year-old woman who was diagnosed as having sigmoid colon cancer after presenting with complete rectal prolapse. The rectal prolapse was considered to have been caused by constipation accelerated by the colon cancer. The relationship between colorectal cancer and rectal prola...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02483019

    authors: Yamazaki T,Sakai Y,Sekine Y,Nihei K,Hatakeyama K

    更新日期:1999-01-01 00:00:00

  • Multiple primary cancers associated with esophageal carcinoma.

    abstract::This study was conducted to examine the characteristics of esophageal cancers with primary synchronous or metachronous cancer in another organ. We retrospectively evaluated 744 patients who underwent esophagectomy for esophageal cancers between 1985 and 1998. The patients were divided into two groups according to whet...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s005950170025

    authors: Kumagai Y,Kawano T,Nakajima Y,Nagai K,Inoue H,Nara S,Iwai T

    更新日期:2001-01-01 00:00:00

  • Repeated colon penetration by an ingested fish bone: report of a case.

    abstract::A 78-year-old man was admitted to Kumamoto Rosai Hospital with right lower abdominal pain. Abdominal computed tomography (CT) showed penetration of the cecum by a foreign body, which looked like a fish bone, as well as thickening of the right lower abdominal wall. We made an initial diagnosis of penetration of the col...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-007-3629-y

    authors: Okuma T,Nagamoto N,Tanaka E,Yoshida Y,Inoue K,Baba H

    更新日期:2008-01-01 00:00:00

  • The advantages of normocalcemic continuous warm cardioplegia over low calcemic cardioplegia in myocardial protection.

    abstract::The effects of changing the calcium content of a continuous warm hyperkalemic crystalloid cardioplegia (CWCP) were investigated in an isolated rat heart preparation. The hearts were divided into eight groups of six each. A control group consisted of fresh nonarrested hearts and the remaining seven groups consisted of ...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF02482780

    authors: Nakamura Y,Takemoto N,Kuroda H,Ohgi S

    更新日期:1999-01-01 00:00:00

  • Surgical treatment of an enormous aneurysmal portahepatic venous fistula: report of a case.

    abstract::We report herein the case of a 20-year-old woman in whom an enormous aneurysmal portahepatic venous fistula was found. The portal aneurysm developed in the anterior inferior segment of the right hepatic lobe, and communicated with the right portal vein and the right hepatic vein. Due to the enormous size of the shunt,...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/BF00311468

    authors: Miyauchi A,Okada S,Hashimoto T,Wakabayashi H,Maeba T,Tanaka S,Hayashi H

    更新日期:1995-01-01 00:00:00

  • Accessory splenectomy with gastroesophageal devascularization for recurrent hypersplenism and refractory bleeding varices in a patient with liver cirrhosis: report of a case.

    abstract::We report a case of recurrent thrombocytopenia associated with symptomatic enlargement of an accessory spleen, 2 years after splenectomy, in a 36-year-old man with posthepatitic liver cirrhosis. The patient suffered three episodes of variceal bleeding, but the esophageal varices were not eradicated by two sessions of ...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s00595-004-2837-y

    authors: Mishin I,Ghidirim G

    更新日期:2004-01-01 00:00:00

  • Pure laparoscopic right hepatectomy in the semi-prone position using the intrahepatic Glissonian approach and a modified hanging maneuver to minimize intraoperative bleeding.

    abstract:PURPOSE:Although laparoscopic liver resection has been widely adopted, performing a pure laparoscopic right hepatectomy remains a challenging procedure. The aim of this report is to evaluate the efficiency of a pure laparoscopic right hepatectomy (PLRH) in the semi-prone position using the intrahepatic Glissonian appro...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-010-4479-6

    authors: Ikeda T,Yonemura Y,Ueda N,Kabashima A,Shirabe K,Taketomi A,Yoshizumi T,Uchiyama H,Harada N,Ijichi H,Kakeji Y,Morita M,Tsujitani S,Maehara Y

    更新日期:2011-12-01 00:00:00

  • Translation and validation of the Japanese version of the fecal incontinence quality of life scale.

    abstract:PURPOSE:The aim of the study was to conduct a psychometric evaluation of the fecal incontinence quality of life scale (FIQL) in the Japanese language using rigorous methodologies. METHODS:The FIQL was translated into Japanese. After being linguistically validated, the Japanese version of the FIQL was administered to a...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/s00595-012-0412-5

    authors: Tsunoda A,Yamada K,Kano N,Takano M

    更新日期:2013-10-01 00:00:00

  • Double common bile duct with choledochal cyst and cholelithiasis: report of a case.

    abstract::Double common bile duct (DCBD) is a rare congenital anomaly of the biliary system, often associated with biliary lithiasis, choledochal cyst, pancreaticobiliary maljunction (PBM), and upper gastrointestinal tract malignancies. We report a case of type I DCBD with choledochal cyst and cholelithiasis in a 52-year-old Ch...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s00595-013-0561-1

    authors: Chen G,Wang H,Zhang L,Li Z,Bie P

    更新日期:2014-04-01 00:00:00

  • An experimental study on spinal cord ischemia during cross-clamping of the thoracic aorta: the monitoring of spinal cord ischemia with motor evoked potential by transcranial stimulation of the cerebral cortex in dogs.

    abstract::The usefulness of spinal motor evoked potential by transcranial stimulation of the motor cortex (MEPT) in detecting spinal ischemia and predicting postoperative neurological dysfunction was evaluated using a model of spinal ischemia. Group 1 was comprised of 11 dogs used for measuring the basic wave form of spinal MEP...

    journal_title:Surgery today

    pub_type: 杂志文章

    doi:10.1007/BF00309095

    authors: Shokoku S,Uchida H,Teramoto S

    更新日期:1993-01-01 00:00:00

  • Pregnancy after undergoing the Fontan procedure for a double outlet right ventricle: report of a case.

    abstract::We describe a 25-year-old woman who had a successful pregnancy after the repair of a double outlet right ventricle using the Fontan procedure. Although the number of reported patients is small, women who have good hemodynamic results after the operation can apparently tolerate both pregnancy and delivery. ...

    journal_title:Surgery today

    pub_type: 杂志文章,评审

    doi:10.1007/s595-002-8115-4

    authors: Ito M,Takagi N,Sugimoto S,Oosawa H,Abe T

    更新日期:2002-01-01 00:00:00