Abstract:
:The objective of the investigation was to document the clinical presentations of a group of patients with neurofibromatosis type two syndrome (NF2), and took the form of a retrospective case note review. The investigation took place in the tertiary referral skull base unit. The dominant presentation of patients with NF2 is with auditory/vestibular symptoms (56%), with a smaller proportion of presentations being due to non-acoustic intracranial and spinal tumours (44%). At the time of presentation the majority of clinically significant tumours could be demonstrated in each patient with MRI of the head and spine, with few new tumours arising during the subsequent follow-up period. The range of presentation of patients with NF2 results in their management being fragmented into a variety of clinical setting, diluting the experience amassed in any one centre.
journal_name
Br J Neurosurgjournal_title
British journal of neurosurgeryauthors
da Cruz MJ,Hardy DG,Moffat DAdoi
10.1080/02688690050004507subject
Has Abstractpub_date
2000-04-01 00:00:00pages
101-4issue
2eissn
0268-8697issn
1360-046Xjournal_volume
14pub_type
杂志文章abstract::Isolated intrasellar pituitary mucocele following transsphenoidal sinus surgery is extremely rare. The clinical features resemble a pituitary tumor, therefore careful radiological interpretation is crucial to reach the correct diagnosis. We report a case of intrasellar mucocele who had transsphenoidal sinus surgery pe...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.817535
更新日期:2014-06-01 00:00:00
abstract::We present a surgical series of 74 patients (30 males and 44 females) with pathologically verified cavernous angiomas of the intracranial and orbital compartments. Patients were admitted between 1975 and 1991; six had a family history of cerebral cavernomas, and two had multiple (two) lesions. The 76 malformations wer...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699308995075
更新日期:1993-01-01 00:00:00
abstract::The debate regarding whether to perform an interbody fusion after anterior cervical discectomy (ACD) has been going on for the last 50 years. Several prospective randomized clinical trials have been performed to evaluate the clinical outcome following anterior cervical discectomy with and without interbody fusion. Non...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690802610249
更新日期:2009-02-01 00:00:00
abstract::Oral contraceptives have been implicated in the pathogenesis of dural venous thrombosis. No similar association has been confirmed between postmenopausal hormone replacement therapy and cerebral venous thrombosis, although one previous report in the literature has identified such a case. We present a further case of t...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699550040819
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:In this study, we investigated the effect of local injection of ropivacaine and bupivacaine with magnesium sulfate on postoperative pain in vertebral laminectomy surgery. DESIGN:This randomized double-blind prospective study was conducted among 60 patients aged 18-65 years old with ASA class I and II. METHODS...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1861430
更新日期:2020-12-17 00:00:00
abstract::The use of the flexible neuroendoscope and laser fenestration in the surgical management of a symptomatic cyst of cavum septum pellucidum is reported. Successful communication was established between the cyst cavity and the lateral ventricles using this technique. Satisfactory clinical and radiological improvement as ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699550041179
更新日期:1995-01-01 00:00:00
abstract::Cortical thermal clearance was used during surgery for clipping of a giant middle cerebral artery (MCA) aneurysm. During prolonged continuous proximal MCA occlusion thermal clearance remained normal, indicating sufficient collateral blood supply. Postoperatively the patient had no neurological deficit. This monitoring...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699308995097
更新日期:1993-01-01 00:00:00
abstract::In the first prospective comparison of 'scan-negative' (n=11) and 'scan-positive' (n=7) patients with cauda equina syndrome (CES) we found that Hoover's sign of functional leg weakness but not routine clinical features differentiated the two groups (p<0.02). This offers a new direction of study in this area, although ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2014.1003032
更新日期:2015-04-01 00:00:00
abstract::Two cases of vertigo with subclavian artery stenosis are presented. In both cases, the angiograms revealed left subclavian artery stenosis at the middle portion of the clavicle as well as kinked origin of the vertebral artery. After resection of the anterior scalene muscle, the stenosis and the vertigo resolved. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.3109/02688699008992713
更新日期:1990-01-01 00:00:00
abstract::Knowledge of post-traumatic cerebral haemodynamic disturbances might be beneficial for predicting the management outcome when measuring the basal cerebral arteries blood flow velocity by ultrasonic transcranial Doppler device immediately after severe head injury. Thirty patients who sustained severe brain injury under...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690601048104
更新日期:2006-12-01 00:00:00
abstract::We present our experience with suprabow minicraniotomy in the excision of 18 suprasellar tumours between May 2001 and September 2003. There were 14 females and four males with ages ranging from 7 to 59 years. The tumours included one epidermoid cyst, 10 meningiomas, five craniopharyngiomas and two optico-chiasmatico-h...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690500089415
更新日期:2005-02-01 00:00:00
abstract::Pial arteriovenous fistula (AVF) is a rare vascular lesion, with less than 120 reported cases in the English literatures (Hoh et al., Neurosurgery 2001;49(6):1351). The angio-architecture, clinical course and therapeutic options are all different from arteriovenous malformation (AVM), dural AVM or other intracranial v...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.3109/02688697.2011.566382
更新日期:2011-10-01 00:00:00
abstract::OCT4 expresses variably in primary intracranial germinomas. In this study, we tested our hypothesis that such variation of OCT4 is predictive of outcome in primary intracranial germinomas. Thirty-one histologically identified CNS germinoma patients were enrolled in our study. We collected medical data, immunohistochem...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2011.605483
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Wide-necked and non-saccular aneurysms are difficult to treat with coil embolization. The use of stents has expanded the role of endovascular treatment. METHODS:A retrospective study of 43 patients with wide-necked, fusiform or blister aneurysms treated with stent-assisted coiling or stent alone. The review...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2012.757292
更新日期:2013-10-01 00:00:00
abstract::Background: Vertebral body compression fractures are one of the most common causes of disability and morbidity, especially among the elderly population. The present study was performed in order to evaluate the effect of percutaneous balloon kyphoplasty (BKP) on patients' pain and quality of life (QOL) in Iran.Methods:...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1777254
更新日期:2020-06-09 00:00:00
abstract::Background: When treating intracranial aneurysms with open microsurgery, rare cases arise in which an ipsilateral approach leads to poor visualization, lack of proximal control, or potential damage to nearby vital structures due to the anatomy of the aneurysm. Case Description: We describe a patient with a small, unru...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1648754
更新日期:2019-07-31 00:00:00
abstract::Drug resistance in many cancers outside the CNS has been associated with over-expression of the multidrug resistance gene (MDR1), which codes for the transmembrane efflux pump P-glycoprotein (Pgp). To determine whether tumours of the neuroaxis over-express MDR1 and to identify the site of Pgp expression we examined 50...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699409002952
更新日期:1994-01-01 00:00:00
abstract::Giant anterior circulation aneurysms and some basilar aneurysms can cause problems due to their size, the presence of clot in the aneurysm and the difficulty of applying a clip without kinking the perforating vessels. By utilising cardiopulmonary bypass via the femoro-femoral perforating vessels. By utilising cardiopu...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688698709035310
更新日期:1987-01-01 00:00:00
abstract::Chordoid glioma, a rare tumour of the third ventricle, has distinctive histological appearances. Fewer than 20 cases have been reported in the literature, all but three in females. This paper describes a 54-year-old man with a chordoid glioma and reviews the clinicopathological features of this lesion. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688690120036865
更新日期:2001-04-01 00:00:00
abstract::Purpose: Decompressive craniectomy (DC) is widely used to treat raised intracranial pressure (ICP) in cranial trauma and stroke. It is accompanied by numerous complications. The aim of our study is to assess the surgical treatment of infections related to the use of a dural substitute with concurrent CSF leakage perfo...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2020.1735301
更新日期:2020-03-06 00:00:00
abstract::The aim of this study was to investigate prognostic factors and the most appropriate treatment for patients with ruptured middle cerebral artery (MCA) aneurysms in relation to haematoma distribution. Ninety-two patients with ruptured MCA aneurysms, who underwent surgery during the last 11 years from 1986 to 1996, were...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688699944131
更新日期:1999-02-01 00:00:00
abstract::A patient with von Recklinghausen's disease presented with a right sixth nerve palsy. Investigations demonstrated unilateral dolichoectasia of the intracranial carotid artery and sphenoid wing dysplasia. This case demonstrates an association not previously documented, that of unilateral fusiform dilatation of the caro...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688699409027975
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:To assess changes in neurological function after cranioplasty. METHODS:Functional and neurocognitive assessments including activities of daily living assessment, functional independence measure (FIM) and the Cognitive assessment report (COGNISTAT) were conducted on all patients within 72 h before and 7 days...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688697.2013.817532
更新日期:2013-10-01 00:00:00
abstract::A theoretical evaluation of the lifetime probabilities of different outcomes in patients with unruptured intracranial aneurysms (UA) has been made using a life table method. The calculations were performed for aneurysm presenting ages from 20 to 70 years of age for men and women assuming an annual risk of aneurysm rup...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.3109/02688698809001009
更新日期:1988-01-01 00:00:00
abstract::An obese woman with benign intracranial hypertension had been managed for several years with lumbo-peritoneal shunting. Following a bilopancreatic procedure performed for management of her obesity dense peritoneal adhesions caused repeated shunt failure. The shunt system was successfully converted to a lumbo-atrial sy...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690601127460
更新日期:2006-12-01 00:00:00
abstract::We describe the unique case of a 51-year-old lady who developed a contralateral lumbosacral plexopathy two days after a lumbar microdiscectomy. This is the first report to date of this complication occurring following this procedure. We review the literature regarding lumbosacral plexopathy and discuss the evidence ba...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2018.1429568
更新日期:2020-08-01 00:00:00
abstract::Spontaneous pneumocephalus is exceptionally rare, with few published cases in the literature. We describe a patient presenting with dysphasia, right facial weakness, headache and confusion who was subsequently found to have pneumocephalus due to an encephalocoele herniating into a tegmen tympani defect. ...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1643008
更新日期:2020-12-01 00:00:00
abstract::A 64-year-old Caucasian woman presented with left eye pain and a transient left oculomotor nerve palsy. Subsequent imaging revealed a mass involving the sphenoid sinus and sella with suprasellar extension. A trans-sphenoidal hypophysectomy was performed. Histopathology showed a fungal infection consistent with phaeohy...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688690500390417
更新日期:2005-10-01 00:00:00
abstract::Background: Posterior fossa decompression both with and without duraplasty are accepted treatments for symptomatic adult patients with Chiari Malformations Type 1 (CM-1). There is still debate of the superiority of one technique over the other. The purpose of this study was to determine the clinical and craniometrical...
journal_title:British journal of neurosurgery
pub_type: 杂志文章
doi:10.1080/02688697.2019.1617407
更新日期:2019-10-01 00:00:00
abstract:INTRODUCTION:Patients with cauda equina syndrome (CES) are frequently referred late when neurological damage cannot be reversed. National Guidelines for emergency referral, imaging and treatment of CES contain symptoms and/or signs that are those of late often, irreversible CES. Referral at this stage may be too late f...
journal_title:British journal of neurosurgery
pub_type: 杂志文章,评审
doi:10.1080/02688697.2017.1297364
更新日期:2017-06-01 00:00:00