Comparison of isoflurane, halothane and fentanyl in patients with decreased ejection fraction undergoing coronary surgery.

Abstract:

:The aim of the study was to compare three anaesthetic agents in patients with ejection fraction below 0.40 subjected to coronary revascularization surgery. Twenty five elective coronary surgical patients with ejection fraction below 0.40 were prospectively studied. Premedication was pethidine 1 mg/kg and induction was fentanyl 0.03 mg/kg and pancuronium 0.1 mg/kg. The patients were randomized to one of three maintenance techniques (fentanyl, isoflurane or halothane). Radial arterial pressure, heart rate, right atrial pressure, pulmonary arterial and occluded pressures, and thermodilution cardiac output were measured, and cardiac index and resistance calculated, at the following times: before induction; 5 min after intubation; 2 min after sternotomy; immediately after discontinuation of bypass; 15 min afterwards; immediately after sternal closure; during suture of the skin; 5 min after arrival in the postoperative care unit; and 60 min postoperatively. Mean arterial pressure decreased significantly in the isoflurane group and nonsignificantly in the halothane group after induction. Cardiac index decreased significantly in the isoflurane group and nonsignificantly in the halothane group after induction and after sternotomy. Neither pressure nor flow decreased in patients receiving fentanyl. Following weaning from cardiopulmonary bypass, systemic vascular resistance decreased significantly in all groups. Cardiac index, however, did not increase above control values and arterial pressure consequently decreased; there was no significant difference between groups.

journal_name

Anaesth Intensive Care

authors

Urzua J,Serra M,Lema G,Canessa R,Gonzalez R,Meneses G,Irarrazaval M,Moran S

doi

10.1177/0310057X9602400513

subject

Has Abstract

pub_date

1996-10-01 00:00:00

pages

579-84

issue

5

eissn

0310-057X

issn

1448-0271

pii

1996035

journal_volume

24

pub_type

临床试验,杂志文章,随机对照试验
  • Reinforcing a "low flow" anaesthesia policy with feedback can produce a sustained reduction in isoflurane consumption.

    abstract::A three-month audit of isoflurane consumption at Palmerston North Hospital in 1994 showed an averaged vapour flow rate of approx 85 ml per minute of anaesthesia, equivalent to 1.4% isoflurane at six litres per minute. After purchasing volatile agent analysers, a program encouraging low flow anaesthesia and providing a...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X9802600405

    authors: McKenzie AJ

    更新日期:1998-08-01 00:00:00

  • Tracheobronchial injury secondary to blunt chest trauma: diagnosis and management.

    abstract::Tracheobronchial injury is an uncommon complication in blunt chest trauma. The typical clinical features include haemoptysis, dyspneoa, and air leak. Tracheobronchial injury occurs after high energy impact and is commonly associated with injuries of other vital organs. If tracheobronchial injury is undetected and left...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章,评审

    doi:10.1177/0310057X0203000204

    authors: Chu CP,Chen PP

    更新日期:2002-04-01 00:00:00

  • Congenital diaphragmatic hernia and the management of persistent foetal circulation.

    abstract::Twenty-two cases of diaphragmatic hernia, presenting from 1978 to 1982, were reviewed. Sixteen patients presented before 24 hours of life, of whom nine survived (56%). Six were late presenters who all did well. Seven babies had ten documented episodes of persistent foetal circulation (PFC) occurring as early as three ...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X8501300407

    authors: Fong LV,Pemberton PJ

    更新日期:1985-11-01 00:00:00

  • Predicting patients at risk of early postoperative adverse events.

    abstract::Adverse events after surgery are common. Identification of markers of at-risk patients may facilitate efficient and effective perioperative resource allocation. This pilot study aimed to identify simple preoperative factors associated with postoperative adverse events. In 1291 surgical patients, the relationship betwe...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X1404200516

    authors: Seglenieks R,Painter TW,Ludbrook GL

    更新日期:2014-09-01 00:00:00

  • Peripartum management of a patient with dopamine beta-hydroxylase deficiency, a rare congenital cause of dysautonomia.

    abstract::We present the first reported case involving the peripartum anaesthetic management of dopamine beta-hydroxylase deficiency in a 22-year-old primigravida with high-grade placenta praevia. Elective caesarean section was performed at 36 weeks gestation with a combined spinal-epidural regional anaesthetic technique. Exten...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X0203000416

    authors: Scurrah NJ,Ross AW,Solly M

    更新日期:2002-08-01 00:00:00

  • Effect of lateral posture on epidural blockade for surgery.

    abstract::In a prospective double-blind study, single-dose lumbar epidural blockade was administered to 60 healthy patients undergoing lower abdominal surgery, the patients lying in the lateral position only during the time of injection of the local anaesthetic. Solutions used were bupivacaine HCl 0.5%, lignocaine HCl 2% and li...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X8301100201

    authors: Seow LT,Lips FJ,Cousins MJ

    更新日期:1983-05-01 00:00:00

  • Predictive performance of a model of anaesthetic uptake with desflurane.

    abstract::We have previously shown that a model of anaesthetic uptake and distribution, developed for use as a teaching tool, is able to predict end-tidal isoflurane and sevoflurane concentrations at least as well as commonly used propofol models predict blood levels of propofol. Models with good predictive performance may be u...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X0603400215

    authors: Kennedy R

    更新日期:2006-04-01 00:00:00

  • A national survey of atropine use by Australian anaesthetists.

    abstract::All Fellows of the Faculty of Anaesthetists, Royal Australasian College of Surgeons (now Australian and New Zealand College of Anaesthetists) were surveyed by mail regarding their use of prophylactic atropine. They were asked whether their usual practice was to give atropine for the following indications: premedicatio...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X9402200110

    authors: Parnis SJ,van der Walt JH

    更新日期:1994-02-01 00:00:00

  • Clinical characteristics and outcomes of patients with obstructive sleep apnoea requiring intensive care.

    abstract::We reviewed the clinical characteristics, required intervention and short- and long-term outcomes in obstructive sleep apnoea (OSA) patients requiring intensive care. A retrospective, single-centre, observational cohort study was undertaken in a multidisciplinary teaching medical and surgical intensive care unit. Adul...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X1003800315

    authors: Hang LW,Chen W,Liang SJ,Lin YC,Tu CY,Chen HJ,Chiu KL

    更新日期:2010-05-01 00:00:00

  • The cerebral and systemic kinetics of thiopentone and propofol in halothane anaesthetized sheep.

    abstract::The cerebral and systemic kinetics of intravenous thiopentone (250 mg over 2 minutes, n=5) and propofol (100 mg over 2 minutes, n=6) were determined in sheep anaesthetized with halothane (2.0%) and mechanically ventilated to an end-expired carbon dioxide tension of 40 mmHg. The sheep were previously instrumented with ...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X0102900205

    authors: Upton RN,Ludbrook GL,Grant C

    更新日期:2001-04-01 00:00:00

  • The influence of head rotation on ProSeal laryngeal mask airway sealing during paediatric myringotomy.

    abstract::Myringotomy with ventilation tube insertion in children involves turning the head from neutral to allow surgical access to the ear. In adults, rotation of the head from the mid-line generally increases the oropharyngeal leak pressure when a ProSeal laryngeal mask airway (PLMA) is used to manage the airway. There are c...

    journal_title:Anaesthesia and intensive care

    pub_type: 临床试验,杂志文章

    doi:10.1177/0310057X0703500617

    authors: Choi WJ,Kim YH

    更新日期:2007-12-01 00:00:00

  • Explosion and fire in the expiratory limb of a Fisher and Paykel "three in one" respiratory care system.

    abstract::We report an incident involving a Fisher and Paykel "There in One Respiratory Care System" (Fisher and Paykel Healthcare, Auckland, New Zealand). This is a new ventilator circuit designed to be adaptable to the needs of ventilator, intubated CPAP, and mask therapies. In this case the patient had received eight hours o...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X9802600415

    authors: Gowardman JR,Moriarty B

    更新日期:1998-08-01 00:00:00

  • Central venous and pulmonary artery occlusion pressures following air embolism in upright sheep.

    abstract::A study on five upright (head above thorax) anaesthetised sheep demonstrated a statistically significant increase in central venous pressure and decrease in pulmonary artery occlusion pressure, following the injection of air 2 ml per kg into the pulmonary artery. In two out of the five sheep after air embolism, right-...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X8401200408

    authors: Pfitzner J,McLean AG

    更新日期:1984-11-01 00:00:00

  • Comparison of remifentanil and fentanyl in anaesthesia for elective cardioversion.

    abstract::This prospective, randomized, double-blind study was designed to compare the recovery characteristics of remifentanil and fentanyl in combination with propofol for direct current cardioversion. Patients undergoing elective cardioversion received either intravenous fentanyl 1 microg/kg (n=33) or remifentanil 0.25 micro...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/0310057X0603400309

    authors: Maltepe F,Kocaayan E,Ugurlu BS,Akdeniz B,Guneri S

    更新日期:2006-06-01 00:00:00

  • Human serum albumin induced hypotension in the postoperative phase of cardiac surgery.

    abstract::Hypotension associated with the rapid infusion of human serum albumin products was first recognised in Australasia in the early 1970s. An association with the angiotensin converting enzyme inhibitor class of drugs (ACE-I) followed, leading to a proposed mechanism involving bradykinin generation through pre-kallikrein ...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X0102900604

    authors: Howard G,Downward G,Bowie D

    更新日期:2001-12-01 00:00:00

  • Opioids, ventilation and acute pain management.

    abstract::Despite the increasing use of a variety of different analgesic strategies, opioids continue as the mainstay for management of moderate to severe acute pain. However concerns remain about their potential adverse effects on ventilation. The most commonly used term, respiratory depression, only describes part of that ris...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章,评审

    doi:10.1177/0310057X1103900405

    authors: Macintyre PE,Loadsman JA,Scott DA

    更新日期:2011-07-01 00:00:00

  • The bispectral index during an anaphylactic circulatory arrest.

    abstract::A 47-year-old woman with Cushing's syndrome suffered a severe anaphylactic reaction on induction of anaesthesia, resulting in circulatory arrest. A spontaneous cardiac output appeared after 25 minutes of chest compression and she regained consciousness three hours later, with no neurological deficit. A Bispectral Inde...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X0102900518

    authors: Kluger MT

    更新日期:2001-10-01 00:00:00

  • A six-month evaluation of the VivaSight™ video double-lumen endotracheal tube after introduction into thoracic anaesthetic practice at a single institution.

    abstract::For a six-month period, all airway options used for non-emergent patients undergoing thoracic surgery requiring one-lung ventilation at a single institution were assessed after introduction of the VivaSight™ double-lumen endotracheal tube (VivaSight-DL), a novel double-lumen tube with an integrated camera. This device...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X1704500208

    authors: Rapchuk IL,Kunju S,Smith IJ,Faulke DJ

    更新日期:2017-03-01 00:00:00

  • Impact of increasing overnight intensive care unit registrar staffing on duration of intubation of elective cardiac surgery patients.

    abstract::It is unclear whether increases to overnight junior medical staffing levels can improve ICU patient outcomes. We conducted a retrospective cohort study before and after the introduction of a third overnight ICU registrar at a 24-bed metropolitan ICU in February 2012. We hypothesised that this change would be associate...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X1504300508

    authors: Durie ML,Darvall JN,Rechnitzer T,Tacey MA

    更新日期:2015-09-01 00:00:00

  • Bacterial contamination of propofol in the operating theatre.

    abstract::There have been several reports of propofol becoming extrinsically contaminated with bacteria. These reports have usually related to infusions or delays in administration after the ampoule has been opened. This observational study was performed to examine bacterial contamination of propofol during usual practice in th...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X9902700510

    authors: Soong WA

    更新日期:1999-10-01 00:00:00

  • The diagnosis of acute anaphylactoid reactions to anaesthetic drugs.

    abstract::Patients with a presumptive diagnosis of an acute anaphylactoid reaction to anaesthesia were investigated to determine the cause of the reaction and the drug responsible by intradermal testing, patch and prick testing, sequential complement measurement, passive transfer testing and challenge. The most valuable informa...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X8100900305

    authors: Fisher MM

    更新日期:1981-08-01 00:00:00

  • Peripheral tissue oxygenation and the number of organs transplanted per donor.

    abstract::Current donor management practices target macrohaemodynamic parameters, but it is unclear if this leads to improvements in microvascular perfusion and tissue oxygenation; the latter may have more impact on organ status. In a recent preclinical study we determined that brain death impaired tissue perfusion and oxygen u...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X1804600611

    authors: Perez-Protto SE,Reynolds JD,Nazemian R,You J,Hata JS,Latifi SQ,Lebovitz DJ

    更新日期:2018-11-01 00:00:00

  • Comparison of haemodynamic responses following different concentrations of adrenaline with and without lignocaine for surgical field infiltration during cleft lip and cleft palate surgery in children.

    abstract::Surgical field infiltration with adrenaline is common practice for quality surgical field during cleft lip and palate repair in children. Intravascular absorption of adrenaline infiltration often leads to adverse haemodynamic responses. In this prospective, double-blinded, randomised study the haemodynamic effects, qu...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/0310057X1204000112

    authors: Muthukumar M,Arya VK,Mathew PJ,Sharma RK

    更新日期:2012-01-01 00:00:00

  • Uterine rupture and scar dehiscence. A five-year survey.

    abstract::A review of the medical records from two public hospitals in Sydney was undertaken to determine the incidence of this uncommon complication. Twenty-seven cases of uterine rupture were reported out of 31,115 deliveries with an incidence of 0.086% (versus 0.05% in the current literature). The incidence associated with p...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X9602400612

    authors: Lynch JC,Pardy JP

    更新日期:1996-12-01 00:00:00

  • Anaesthetic assistants: their role in the development and resolution of anaesthetic incidents.

    abstract::Trained anaesthetic assistants are considered essential for the safe conduct of anaesthesia. Data from 5837 AIMS (Anaesthetic Incident Monitoring Study) reports were evaluated for issues concerning anaesthetic assistants in the generation and resolution of anaesthetic incidents. "Inadequate assistance" as a contributi...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X9902700308

    authors: Kluger MT,Bukofzer M,Bullock M

    更新日期:1999-06-01 00:00:00

  • Adverse local reactions to amethocaine cream--audit and case reports.

    abstract::Amethocaine has recently been introduced as a topical local anaesthetic preparation. Following sporadic reports of severe local adverse effects, we conducted an audit of 372 children attending our hospital for day surgery. We conclude that 4% amethocaine cream is a safe and effective topical anaesthetic and that the i...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X9802600316

    authors: Wongprasartsuk P,Main BJ

    更新日期:1998-06-01 00:00:00

  • Neuroimmune mechanisms of pain: Basic science and potential therapeutic modulators.

    abstract::This narrative review aims to describe the role of peripheral and central immune responses to tissue and nerve damage in animal models, and to discuss the use of immunomodulatory agents in clinical practice and their perioperative implications. Animal models of pain have demonstrated that nerve injury activates immune...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章,评审

    doi:10.1177/0310057X20902774

    authors: Lim JS,Kam PC

    更新日期:2020-05-01 00:00:00

  • The Australian Incident Monitoring Study. Problems with regional anaesthesia: an analysis of 2000 incident reports.

    abstract::There were 160 incidents associated with regional anaesthesia amongst the first 2000 incidents reported to the Australian Incident Monitoring Study. They were categorised into 6 groups; epidural anaesthesia (83), spinal anaesthesia (42), brachial plexus blocks (14), intravenous local anaesthesia (4), ocular blocks (3)...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X9302100526

    authors: Fox MA,Webb RK,Singleton R,Ludbrook G,Runciman WB

    更新日期:1993-10-01 00:00:00

  • Incidence of ventricular fibrillation after aortic cross-clamp release using lignocaine cardioplegia.

    abstract::The occurrence of ventricular fibrillation after aortic de-clamping during cardiac surgery is common, and if prolonged may contribute to myocardial ischaemia. The use of lignocaine cardioplegia to minimize reperfusion ventricular fibrillation was studied in 141 patients undergoing first time coronary artery surgery in...

    journal_title:Anaesthesia and intensive care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1177/0310057X9402200420

    authors: Wallace SR,Baker AB

    更新日期:1994-08-01 00:00:00

  • Adhesive properties of Micropore, Transpore, Leucoplast and Sleek.

    abstract::Adhesive tapes are a routine part of every anaesthetic. Until now there has been little clinical data on the efficacy of these tapes. This study compared Micropore Transpore, Leukoplast and Sleek to determine if any significant difference existed between the adhesive properties of these tapes. The tapes were trialled ...

    journal_title:Anaesthesia and intensive care

    pub_type: 杂志文章

    doi:10.1177/0310057X0203000214

    authors: Chaffer JE,Moyle E

    更新日期:2002-04-01 00:00:00