Effects of vancomycin linoleic acid nanoparticles on male reproductive indices of Sprague-Dawley rats.

abstract：:Radial diffusivity profiles of atomized (MC, d = 1800 ± 200 µm) and inkjet-printed (MI, d = 40 ± 5 µm) alginate-based artificial cells have been generated using 2D Fluorescence Microscopy. The passive outward diffusion of FITC-Dextrans from MIs (0.5% LV alginate/15% CaCl2 coated with 0.5% Chitosan) and MCs (1.5% MV al...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Mobed-Miremadi M,Asi B,Parasseril J,Wong E,Tat M,Shan Y

更新日期：2013-06-01 00:00:00

abstract：:To prepare ethosome gel containing simvastatin ethosome and investigate the permeation behavior of simvastatin from ethosome gel. Cumulative permeation quantity in unit area and intradermal retention were the indicators to evaluate the effects of simvastatin in vitro percutaneous permeation behavior. Cumulative permea...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： An K,Sun Y,Wu Y,Yuan H,Cui Z,Xu L

更新日期：2013-10-01 00:00:00

abstract：:Poly(ethylene glycol)-Poly(lactic acid) block-copolymer (PEG-PLA) was prepared and characterized using Fourier transform infrared spectrophotometer (FTIR). Glutaraldehyde was used to crosslink stroma-free hemoglobin (SFHb), superoxide dismutase (SOD), catalase (CAT), and carbonic anhydrase (CA) into a soluble complex ...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Gao W,Bian Y,Chang TM

更新日期：2013-08-01 00:00:00

abstract：:In this study, a Soluplus-coated colloidal silica nanomatrix (SCCSN) formulation for the entrapment of poorly water-soluble drugs was devised. The maximum supersaturation of the drug-loaded nanomatrix was higher than that of a physical mixture as indicated by the results of in vitro kinetic solubility studies. For ato...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Kim MS

更新日期：2013-12-01 00:00:00

abstract：:We investigated the pre-clinical utility of carbon monoxide form of PEGylated hemoglobin (PEG-Hb also named SANGUINATE(™)) in myocardial infarction (MI) and in particular the response of diabetic tissues to superimposed ischemia/reperfusion injury. SANGUINATE(™) was evaluated in diabetic and normal mice subjected to 3...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Ananthakrishnan R,Li Q,O'Shea KM,Quadri N,Wang L,Abuchowski A,Schmidt AM,Ramasamy R

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVES:To reduce the mean molecular weight [Formula: see text] and to increase the effective polymerization ratio (REff) of polymerized human placenta hemoglobin (PolyPHb). METHODS:Three factors of GDA-PolyPHb process such as the approach of feeding GDA (FGDA), hemoglobin concentration ([Hb]) and the molar ratio o...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Zhou W,Zhao L,Wang J,Li S,Chen G,Liu J,Yang C

更新日期：2013-10-01 00:00:00

abstract：:A novel non-competitive amperometric immunosensor based on a self-assembled monolayer (SAM) of thiourea modified by a polymeric Schiff's base of glutaraldehyde on gold electrode has been developed for determination of IgM. Alkaline phosphatase (ALP)-conjugated monoclonal anti-mouse immunoglobulin M (IgM) antibody was ...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Akyilmaz E,Dinçkaya E

更新日期：2013-12-01 00:00:00

abstract：:The use of nanoparticles is under intense investigation. The possible advantages proposed by these systems are very impressive and the results may be quite schemer. In this scenario, the association of nanoparticles with radioactive materials (radionuclide) may be the most important step since the discovery of radioac...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Albernaz Mde S,Ospina CA,Rossi AM,Santos-Oliveira R

更新日期：2014-04-01 00:00:00

abstract：:A new series of isoquinoline urea/thiourea derivatives (1-11) were synthesized, and their inhibitory effects on tyrosinase were evaluated. Isoquinoline urea/thiourea derivatives were obtained as a result of the reaction of 5-aminoisoquinoline with isocyanates or isothiocyanates. The result showed that all the synthesi...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Genç H,Zengin M,Yavuz E,Gençer N,Arslan O

更新日期：2014-06-01 00:00:00

abstract：CONTEXT:The conjugation of silver nanoparticles (AgNPs) with biomolecules such as oligosaccharides, DNA, proteins has attracted great attention of scientists recently. OBJECTIVE:In this study, lysozyme-AgNP conjugates were evaluated for its synergic antimicrobial effect. MATERIALS AND METHODS:AgNPs were synthesized a...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Ernest V,Gajalakshmi S,Mukherjee A,Chandrasekaran N

更新日期：2014-10-01 00:00:00

abstract：:Abstract The aim of this study is to prepare nonwoven fabrics carrying silver nanoparticles (AgNPs), and to investigate their antibacterial activities and cytotoxicities in parallel. AgNPs were impregnated from their nanoemulsions onto two commercially available nonwoven fabrics: pure-cotton fabrics (PCF) and polyeste...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Moghtader F,Salouti M,Türk M,Pişkin E

更新日期：2014-12-01 00:00:00

abstract：CONTEXT:Congenital heart disease is a leading cause of death in the first year, with an incidence of 1.5 million worldwide. It can be treated with bypass surgery, but due to the limited availability of autologous grafts, there has been research into developing a completely tissue-engineered vascular graft. Our group ha...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Lakhani HA,de Mel A,Seifalian AM

更新日期：2015-01-01 00:00:00

abstract：:In this study, lyophilization was applied to polymerized human placenta hemoglobin (PolyPHb) solution. The lyophilization process was carried out with freezing at - 70°C for 5 h and two phases of drying: the first phase of drying was carried out at -35°C-35°C for 16 h and the second phase at 35°C for 8 h. Hemoglobin (...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Zhao L,Zhou W,Wang J,Li S,Chen G,Liu J,Yang C

更新日期：2014-04-01 00:00:00

abstract：:Small bowel transplantation (SBTx) has become a standard clinical treatment for short bowel syndrome or irreversible intestinal function failure. Optimum preservation of the organ is essential for the success of transplantation. In this study, pPolyHb was used as an additive to hypertonic citrate adenine solution (HCA...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Huang H,Ma J,Zhu W,Sun J,Yan K,Song B,Xue Y,Xin J,Pan W,Zhu H,Chen C

更新日期：2014-10-01 00:00:00

abstract：:PEGylation of intramolecularly crosslinked Hb has been studied here to overcome the limitation of dissociation of Hb tetramers. New hexa and deca PEGylated low oxygen affinity PEG-ααHbs have been generated. Influence of PEG conjugation chemistry and the PEG shell structure on the functional properties as well as PEGyl...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Meng F,Tsai AG,Intaglietta M,Acharya SA

更新日期：2015-01-01 00:00:00

abstract：:In this study, a series of semi-interpenetrating polymer network (IPN) hydrogels were prepared as a support material for lipase immobilization. Hydrogels were synthesized via free radical polymerization in different compositions of chitosan (Cs), acrylamide (AAm), and citraconic acid (CA). The swelling values of the h...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Pulat M,Akalın GO,Karahan ND

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:To examine the effects of sodium pyruvate (SP) on metabolic acidosis. METHODS:For the in vivo experiments, we evaluated effects of SP on an ammonium chloride (NH4Cl)-induced hyperchloremic acidosis rat model. SP was infused at overall doses of 2, 4, and 6 mmol·kg(- 1) for the SP1, SP2, and SP3 groups, respec...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Yang J,Zhao JX,Wang Y,Chen G,Cheng WN,Luo X,Pei XT,Zhao L,Su Q,Zhou H

更新日期：2016-01-01 00:00:00

abstract：:Permeability plays an important role to achieve the desired therapeutic outcomes. Present study was designed to investigate the permeability of ciprofloxacin from ultrathin polyvinyl alcohol nanofiber through different biological membranes. Results of the permeability studies indicated that nanofibers exhibit higher d...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Modgill V,Garg T,Goyal AK,Rath G

更新日期：2016-01-01 00:00:00

abstract：:The main objective of the present article was to prepare stable and well-dispersible budesonide (BUD) nanosuspensions by microfluidizer method. The morphology, particle size, and zeta potential of formulation were investigated and in vitro release and in vivo lung distribution were evaluated. Characterizations showed ...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Zhang Y,Zhang J

更新日期：2016-01-01 00:00:00

abstract：:A new microring resonator system is proposed for the detection of the Salmonella bacterium in drinking water, which is made up of SiO2-TiO2 waveguide embedded inside thin film layer of the flagellin. The change in refractive index due to the binding of the Salmonella bacterium with flagellin layer causes a shift in th...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Bahadoran M,Noorden AF,Mohajer FS,Abd Mubin MH,Chaudhary K,Jalil MA,Ali J,Yupapin P

更新日期：2016-01-01 00:00:00

abstract：:A novel impedimetric biosensor utilizing a biological receptor, vascular endothelial growth factor receptor-1 (VEGF-R1), was developed for the determination of vascular endothelial growth factor (VEGF). VEGF-R1 was covalently immobilized by coupling with 11-mercaptoundecanoic acid, which formed a self-assembled monola...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Bahadır EB,Sezgintürk MK

更新日期：2016-01-01 00:00:00

abstract：:Magnetic iron oxide nanoparticles have become the main candidates for biomedical and biological applications, and the application of small iron oxide nanoparticles in in vitro diagnostics has been practiced for about half a century. Magnetic nanoparticles (MNPs), in combination with an external magnetic field and/or m...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Zeinali Sehrig F,Majidi S,Nikzamir N,Nikzamir N,Nikzamir M,Akbarzadeh A

更新日期：2016-05-01 00:00:00

abstract：:Quantum dots (QDs) as colloidal nanocrystalline semiconductors have exceptional photophysical properties, due to their quantum confinement effects. Depending on their sizes and chemical compositions, QDs emit different wavelengths over a broad range of the light spectrum, from visible to infrared. QDs are typically ex...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Abbasi E,Kafshdooz T,Bakhtiary M,Nikzamir N,Nikzamir N,Nikzamir M,Mohammadian M,Akbarzadeh A

更新日期：2016-05-01 00:00:00

abstract：:In this paper, we demonstrate a simple, sensitive, inexpensive, disposable and label-free electrochemical nucleic acid biosensor for the detection of the hepatitis C virus genotype 1a (HCV1a). The nucleic acid biosensor was designed with the amino-linked inosine-substituted 20-mer probes, which were immobilized onto a...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Donmez S,Arslan F,Arslan H

更新日期：2016-05-01 00:00:00

abstract：:This paper describes the formulation of archaeosomes and the evaluation of their abilities to facilitate in vitro DNA delivery. Lipids of the H.hispanica 2TK2 strain were used in archaeosome formation, which is formulated by mixing H.hispanica 2TK2 lipids with plasmid DNA encoding green fluorescent protein (GFP) or β-...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Attar A,Ogan A,Yucel S,Turan K

更新日期：2016-01-01 00:00:00

abstract：:This study deals with the development of interpenetrating polymer network (IPN) microspheres of acrylamide (AAm) grafted onto a chitosan (CS) backbone and methylcellulose (MC). Chitosan-graft-polyacrylamide (CS-g-PAAm) was synthesized by cerium (IV) ammonium nitrate-induced free radical graft polymerization. The graft...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Bulut E

更新日期：2016-06-01 00:00:00

abstract：:This work describes the synthesis and macromolecular reactions of maleic anhydride (MA)-acrylamide (AAm) binary and MA-vinyl acetate (VA)- AAm ternary reactive copolymers with γ-aminopropyltriethoxysilane (APTS) as a polyfunctional crosslinker. Swelling parameters such as the start-time of the hydrogel-formation, init...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Timur M,Can HK

更新日期：2016-05-01 00:00:00

abstract：:Bcl-2, an antiapoptotic protein, is considered as a potential target in cancer treatment since its oncogenic potential has been proven and is well documented. Antisense technology and RNA interference (RNAi) have been used to reduce the expression of the Bcl-2 gene in many types of cancer cells and are effective as ad...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Jagani H,Kasinathan N,Meka SR,Josyula VR

更新日期：2016-08-01 00:00:00

abstract：:The covalent immobilization of Trichoderma reesei cellulase onto modified ReliZyme HA403 and Sepabeads EC-EP supports were carried out. The optimal immobilization conditions were determined using response surface methodology. The hydrolysis of cellulose using the free and immobilized cellulase preparations in ionic li...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Bilgin R,Yalcin MS,Yildirim D

更新日期：2016-08-01 00:00:00

abstract：:We prepared and evaluated a multifunctional envelope-type nano device (MEND) as a liver-targeting and long-circulation carrier for SiRNA. The polymer GA-PEG-Pp-DOPE was synthesized by modifying polyethylene glycol (PEG) with glycyrrhetinic acid (GA), peptide (Pp), and dioleoyl phosphoethanolamine (DOPE). The Pp is a s...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Zhang Y,Wei H,Xu L,Yan G,Ma C,Yu M,Wei C,Sun Y

更新日期：2016-08-01 00:00:00