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Recombinant human plasma gelsolin (rhu-pGSN) in a patient hospitalized with critical COVID-19 pneumonia.

Abstract：

:Life-threatening COVID-19 pneumonia follows an exaggerated immune response to SARS-CoV-2. pGSN levels fall after SARS-CoV-2 infection. Rhu-pGSN improves outcomes in models of inflammation. In an intubated patient with critical COVID-19 pneumonia and progressive hypoxemia despite standard care, improvement became evident during rhu-pGSN infusions with full recovery within a few weeks.

journal_name

Clin Infect Pract

journal_title

Clinical infection in practice

authors

Catteeuw JV,DiNubile MJ

doi

10.1016/j.clinpr.2021.100088

keywords:

["COVID-19","Inflammation","Recombinant human plasma gelsolin (rhu-pGSN)"]

subject

Has Abstract

pub_date

2021-11-01 00:00:00

pages

100088

issn

2590-1702

pii

S2590-1702(21)00025-X

journal_volume

12

pub_type

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