Abstract：
:A depletion study of toltrazuril and its metabolites was performed using 20 hens medicated via drinking water for two days in a dosage of 7 mg kg-1 per kg body weight. Afterward, eggs were collected for 42 days. Residues were analyzed in whole eggs and yolk and whites. Toltrazuril sulfone was found to be the most predominant in all matrices, the highest concentration was found in the yolk - 5567 µg kg-1, followed by whole eggs samples - 4767 µg kg-1 and egg whites - 532 µg kg-1. On last day toltrazuril sulfone were still detected - 22.5 µg kg-1. 70 days is required to concentration of toltrazuril sulfone reach zero. Administrating toltrazuril before the laying phase can pose a risk of residues of toltrazuril sulfone in eggs. Setting Maximum Residue Limit could reduce the risk of non-complaint samples and ensure the safety of consumers, but still requires 44 days of the withdrawal period.
journal_name
Food Chemjournal_title
Food chemistryauthors
Pietruk K,Olejnik M,Jedziniak Pdoi
10.1016/j.foodchem.2021.130054keywords:
["Depletion","Eggs","Laying hens","Residue","Toltrazuril sulfone","Withdrawal time"]subject
Has Abstractpub_date
2021-10-30 00:00:00pages
130054eissn
0308-8146issn
1873-7072pii
S0308-8146(21)01060-8journal_volume
360pub_type
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