Abstract:
:Background The rapid plasma reagin (RPR) assay is commonly used as a surrogate marker of infectious syphilis, but is non-specific, slow to change and variable in its rate of decline post treatment. METHODS:Within an urban sexual health service testing predominantly men who have sex with men, a file review of RPR changes was undertaken in all subjects who had a dilution level of ≥1:4, between January 2015 to the end of December 2018. RESULTS:Overall, 248 cases of infectious syphilis were identified in 215 subjects (165 HIV seropositive, 50 HIV seronegative). Among unique-subject cases with follow-up RPR recorded, seroreversion to a non-reactive titre was achieved in only 42.3% (71/168) cases at a median of 235 days (interquartile range: 138-348 days) and was significantly less likely if patients had HIV infection (P = 0.02), late latent syphilis (P = 0.003) or a subsequent syphilis infection (P < 0.0001). Having HIV infection (P = 0.03) or a subsequent episode of syphilis (P = 0.01) were associated with a lower likelihood of documented cure. CONCLUSIONS:The slow decay in RPR titres post therapy and the inability of a significant number of subjects to achieve a non-reactive result over time makes RPR a poor test for assessing the adequacy of treatment or in diagnosing re-infection, especially in populations having repeated and frequent risk exposures. As the number of syphilis cases continue to climb, better tests that accurately assess pathogen presence are urgently needed.
journal_name
Sex Healthjournal_title
Sexual healthauthors
Harjanto R,Smith DE,Barratt H,Kelly M,Chan D,Furner V,Smith M,Ronnachit A,Post J,Rawlinson Wdoi
10.1071/SH20043subject
Has Abstractpub_date
2020-08-01 00:00:00pages
330-336issue
4eissn
1448-5028issn
1449-8987pii
SH20043journal_volume
17pub_type
杂志文章相关文献
Sexual Health文献大全abstract::Background Forced migration is associated with sexual vulnerability. However, little is known about the sexual health literacy and needs of refugee-background youth post resettlement. METHODS:Conducted in partnership with the Queensland Sudanese community, this study used a cross-sectional survey to explore the sexua...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH16171
更新日期:2017-06-01 00:00:00
abstract::Chemsex is the colloquial term used for a specific pattern of drug use that is increasingly common among men who have sex with men (MSM) globally. The recreational substances employed are used specifically in a sexualized context. The reasons for chemsex among MSM are complex. The Anova Health Institute (Anova) provid...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH17158
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Chlamydia (Chlamydia trachomatis) is the commonest bacterial sexually transmissible infection worldwide and contributes to significant morbidity in females. We examined potential barriers and facilitating factors for screening in young Victorian women, using the social networking site, Facebook to recruit pa...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH12198
更新日期:2013-07-01 00:00:00
abstract::The introduction of highly active antiretroviral therapy (HAART) has irrevocably changed the nature of the HIV epidemic in developed countries. Although the use of HAART does not completely restore health in HIV-infected individuals, it has dramatically reduced morbidity and mortality. Increases in life expectancy res...
journal_title:Sexual health
pub_type: 杂志文章,评审
doi:10.1071/SH11026
更新日期:2011-12-01 00:00:00
abstract::Sexuality and power are at the root of most sexual and reproductive health problems in Thailand, including reproductive tract infections, fertility and population control, unwanted pregnancy and abortion, unsafe abortion, unsafe motherhood and violence against women, as well as issues emerging from the mobile and migr...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/sh04050
更新日期:2005-01-01 00:00:00
abstract::Background Partner notification (PN) in Australia has been studied and improved in recent decades. International researchers have highlighted the use of electronic communication technologies to assist PN (Internet partner notification or IPN). Using the Australian experience as an example, the aim of this study is to ...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH19007
更新日期:2019-08-01 00:00:00
abstract::Background Understanding people's sexual motivations has long been of public health and health promotion interest. We used daily diaries to examine how adult men's and women's event-specific affective sexual motivations were linked to the types and combinations of sexual behaviours chosen in a given sexual event. MET...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH16109
更新日期:2017-04-01 00:00:00
abstract::Background Common causes of temporal lobe hyper intensities are central nervous system infections like herpes simplex encephalitis, Lyme disease, limbic encephalitis and vascular pathology like Cerebral Autosomal Dominant Arteriopathy with Subcortical infarcts and Leukoencephalopathy. METHODS:Personal assessment, lab...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH17088
更新日期:2018-07-01 00:00:00
abstract:UNLABELLED:Objective To compare condom use motives and behaviours in the context of penile-vaginal intercourse (PVI) with new versus established sexual partners, using daily event-level data among a clinic-recruited sample. METHODS:Participants (ages 15-65 years old) were recruited from five sexually transmissible inf...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH13159
更新日期:2014-07-01 00:00:00
abstract:UNLABELLED:Background Cervical cancer is preventable through screening, and HIV treatment guidelines recommend that all HIV-infected women receive cervical cancer twice during the year after HIV diagnosis and annually thereafter. Different immunohistochemical markers have been studied to highlight cervical intraepithel...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH13144
更新日期:2015-03-01 00:00:00
abstract::Condoms are highly effective for HIV prevention, yet are not currently indicated by the US Food and Drug Administration (FDA) for anal sex. We surveyed a national sample of men who have sex with men to assess whether FDA label indication could affect anticipated condom use, and to determine levels of perceived condom ...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH18152
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:The study examined risk factors for having ever contracted sexually transmissible infections (STI) among a high-risk sample in midwestern USA. METHODS:A cross sectional survey was conducted among 428 homeless youth aged 16-19 years. Assessed correlates included child maltreatment, street exposure, sexual hi...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/sh06045
更新日期:2007-03-01 00:00:00
abstract::In New South Wales (NSW), Australia, innovative community-based testing models have been implemented to increase HIV testing among populations at risk. The characteristics of patients newly diagnosed with HIV at a community-based testing site and at a traditional clinical service in Sydney, NSW, were compared. Compare...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH19152
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Sexually transmissible infections (STIs) are common in female sex workers (FSWs), most of which are asymptomatic and therefore under-reported. Our aim was to determine the sensitivity and specificity of reported symptoms obtained via questionnaire augmented with leukocyte esterase (LE) urine dipstick test fo...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH09093
更新日期:2010-03-01 00:00:00
abstract:BACKGROUND:In Australia, Health Department policies differ on the recommended method of providing HIV results. Traditionally, all results have been provided in person. Our aim was to trial provision of HIV-negative test results by telephone to low-risk clients attending sexual health services and to assess clients' pre...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH10159
更新日期:2012-05-01 00:00:00
abstract:UNLABELLED:Background Men and women with HIV infection are at increased risk of developing cancers associated with human papillomavirus (HPV). The two licensed prophylactic HPV vaccines protect against de novo infection with HPV-16 and HPV-18, which cause the majority of HPV-associated cancers. Currently, no vaccine ef...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH14015
更新日期:2014-12-01 00:00:00
abstract::Rates of sexually transmissible infections (STIs) in remote central Australian Aboriginal communities have been persistently high for over two decades, yet risk factors for STIs in these communities are not well understood. This qualitative study explored behavioural and contextual risk factors for STIs in young Abori...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH19181
更新日期:2020-04-01 00:00:00
abstract::Background The rate of notifications of sexually transmissible infections (STIs) in Australians has increased dramatically, especially in those aged 16-30 years. This age bracket, typical of university students, is the most likely to report multiple sexual partners in the previous year. Individuals who have sex with m...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH16228
更新日期:2018-07-01 00:00:00
abstract::Background Syphilis incidence worldwide has rebounded since 2000, particularly among men who have sex with men (MSM). A predictive model for syphilis infection may inform prevention counselling and use of chemoprophylaxis. METHODS:Data from a longitudinal cohort study of MSM and transgender women meeting high-risk cr...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH17118
更新日期:2018-06-01 00:00:00
abstract:UNLABELLED:Background Syphilis is resurgent among gay and bisexual men (GBM) despite effective treatment and widely available diagnostic serology. The polymerase chain reaction assay for Treponema pallidum (TP-PCR) is available, but little is known about the clinical features and outcomes for patients testing positive ...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH15043
更新日期:2015-11-01 00:00:00
abstract::This report describes a patient with symptomatic Trichomonas vaginalis infection who was unable to tolerate nitroimidazole drugs because of severe hypersensitivity, for which desensitisation was not possible. Use of intravaginal clotrimazole, intravaginal paromomycin, intravaginal furazolidone, povidone-iodine douches...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH11114
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Twenty-four hour access to condoms for young people living in rural Victoria is problematic for many reasons, including the fact that condom vending machines are often located in venues and places they cannot access. METHOD:We partnered with three rural councils to install condom vending machines in locatio...
journal_title:Sexual health
pub_type: 信件
doi:10.1071/SH13050
更新日期:2013-11-01 00:00:00
abstract::Background Extremely high rates of diagnosis of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) have been recorded in remote communities across northern and central Australia. Re-testing at 3 months, after treatment administered, of CT or NG is recommended to detect repeat infections and prevent morbidity an...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH16025
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:The identification of factors associated with delayed diagnosis of HIV infection in Victoria, Australia was the aim of the present study. METHODS:Demographic and epidemiological characteristics of cases notified to the Victorian HIV surveillance database between 1 January 1994 and 31 December 2006 were anal...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH08028
更新日期:2009-06-01 00:00:00
abstract::We investigated whether men who have sex with men (MSM) would use mouthwash daily to prevent pharyngeal gonorrhoea. Ten MSM attending the Melbourne Sexual Health Centre were asked to use a Listerine® alcohol-containing mouthwash daily for 14 days in August 2015. Mouthwash was used at least once daily for 133 of 140 pe...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH16026
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVES:To determine the feasibility and acceptability of screening for sexually transmitted infections and blood-borne viruses and to study the profile of sexual activity and other risk behaviours in a senior high school population. METHODS:In this descriptive study we provided sexual health education and screenin...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/sh05014
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Australia has a widely dispersed network of public sexual health services that test large numbers of people from high prevalence populations for genital Chlamydia trachomatis infection. These populations include young sexually active heterosexuals, men who have sex with men, sex workers and Aboriginal and To...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH09125
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Physicians' inadequate involvement in sexual risk assessment has the potential to miss many asymptomatic cases. The present study was conducted to explore sexual risk assessment by physicians in clinical practice and to identify barriers in eliciting sexual histories from patients. METHODS:A stratified rand...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/sh06012
更新日期:2007-03-01 00:00:00
abstract:INTRODUCTION:In order to review the requirement for all patients to return for HIV test results, we sought to describe the number of cases of HIV infection detected at Sydney Sexual Health Centre among people who did not disclose known risk factors before testing. METHOD:The clinic database identified all HIV testing ...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH09151
更新日期:2010-12-01 00:00:00
abstract::Transgender populations are heavily burdened by HIV and other sexually transmissible infections (STIs). However, data on co-infection with HIV and STIs among transgender people are limited. A systematic review was conducted of peer-reviewed articles and conference abstracts between January 2010 and November 2015 that ...
journal_title:Sexual health
pub_type: 杂志文章
doi:10.1071/SH17096
更新日期:2017-10-01 00:00:00