Abstract:
INTRODUCTION:Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is increasingly used to treat peritoneal metastases from appendiceal or colorectal origin. We evaluate our institution's experience and survival outcomes with this procedure, and its efficacy in symptom relief. METHODS:This is a single-centre retrospective observational study on patients with peritoneal metastases (PM) from appendiceal neoplasm or colorectal cancer who underwent CRS/HIPEC in Queen Mary Hospital. Our primary endpoints were overall survival (OS) and morbidity and mortality of this procedure; secondary endpoints included disease-free survival (DFS) and symptom-free survival. RESULTS:Between 2006 and 2018, thirty CRS/HIPEC procedures were performed for 28 patients - 17 (60.7%) had appendiceal PM while 11 (39.9%) had colorectal PM. The median peritoneal cancer index was 20; complete cytoreduction was achieved in 83.3% patients. High-grade morbidity occurred in 13.3% cases. There was no 30-day mortality. Two-year OS were 71.6% and 50% for low-grade appendiceal PM and colorectal PM patients (p = 0.20). Complete cytoreduction improved OS (2-year OS 75.4% vs 20%, p = 0.04). Median DFS was 11.8 months. Median symptom-free duration was 36.8 months; patients with complete cytoreduction were more likely to remain asymptomatic (82.9% at 1 year, vs 60% in incomplete cytoreduction group, p < 0.01). 91.7% low-grade appendiceal PM patients and 58.4% colorectal PM patients remained asymptomatic at post-operative one year (p = 0.31). CONCLUSION:CRS/HIPEC is beneficial to appendiceal PM and selected colorectal PM patients - improving survival and offering prolonged symptom relief, with reasonable morbidity and mortality. Complete cytoreduction is key to realising this benefit.
journal_name
Asian J Surgjournal_title
Asian journal of surgeryauthors
Chow FC,Yip J,Foo DC,Wei R,Choi HK,Ng KK,Lo OSdoi
10.1016/j.asjsur.2020.05.010subject
Has Abstractpub_date
2021-01-01 00:00:00pages
221-228issue
1eissn
1015-9584issn
0219-3108pii
S1015-9584(20)30140-8journal_volume
44pub_type
杂志文章abstract::Lipomatous ganglioneuroma (LG) is a rare variant of ganglioneuroma that is histologically characterized by a mature adipocytic component admixed with a conventional ganglioneuroma. We report the clinicopathological and immunohistochemical features of an LG in a 44-year-old Chinese male; additionally, we review the lit...
journal_title:Asian journal of surgery
pub_type: 杂志文章,评审
doi:10.1016/j.asjsur.2013.07.011
更新日期:2016-04-01 00:00:00
abstract::Minimally invasive parathyroidectomy (MIP) was introduced into Australia after endocrine surgeons agreed that it should only be undertaken in the context of a feasibility study or controlled trial, and under the auspices of the Australian Safety and Efficacy Register of New Interventional Procedures - Surgical (ASERNI...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(09)60225-6
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:Preservation of the external branch of the superior laryngeal nerve (EBSLN) during thyroidectomy is important because its injury may lead to frequent occurrence of vocal fatigue and the inability to perform superenergetic phonation. Most studies on the anatomy of EBSLN have been performed in Western countrie...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2012.08.003
更新日期:2013-01-01 00:00:00
abstract::We report two cases of prenatally diagnosed cystic neuroblastoma (PDCN). In the first case, prenatal ultrasonography (US) at 33 weeks' gestation showed a 30 x 20 mm cyst at the upper pole of the right kidney. The size and content of the mass demonstrated no change during pregnancy. Postnatal US showed no change in the...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/s1015-9584(09)60309-2
更新日期:2003-10-01 00:00:00
abstract:OBJECTIVE:This study investigated the effects of posture and also intermittent foot and calf compression on peak systolic flow of the popliteal artery in a normal population. METHODS:This was a prospective study carried out in normal subjects at the Vascular Laboratory, Department of Surgery, Hospital Kuala Lumpur, fr...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/s1015-9584(08)60072-x
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:The concept of salvage pulmonary resection after definitive chemoradiotherapy (dCRT) is not yet commonly accepted in lung cancer treatment. We report our experience of eight patients in whom we performed salvage pulmonary resection for residual disease or isolated locoregional recurrence detected a...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2015.05.006
更新日期:2017-04-01 00:00:00
abstract::Massive defects of the upper aerodigestive tract present a reconstructive challenge. We report a case in which a large defect of the naso-oropharyngeal and oesophagus was reconstructed with a combination of a gastric pull-up and a pectoralis major muscle flap. Postoperative function was good and survival was in excess...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(09)60203-7
更新日期:2002-10-01 00:00:00
abstract:OBJECTIVE:This retrospective study aimed to explore the role of Glasgow Aneurysm Score (GAS) and Hardman Index (HI) in predicting outcome after elective endovascular aneurysm repair (EVAR). METHODS:All 71 patients who underwent elective EVAR in a single centre over 9 years were reviewed. Clinical data were used to cla...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(09)60142-1
更新日期:2007-04-01 00:00:00
abstract:BACKGROUND:Routine therapy of metabolic bone disorder (MBD) after gastrectomy for gastric cancer has not been established yet. We have reported that administering an active vitamin D3 agent to patients who had undergone gastrectomy for gastric cancer improved MBD. Recently, the usefulness of alendronate, an osteoclast ...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2016.07.003
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:Various types and materials of stents have been used for urinary diversion in hypospadias surgery. We evaluated whether double pigtail stents are superior to straight silicone stents. METHODS:We conducted a retrospective chart review of all patients who underwent hypospadias surgery with straight silicone or...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(11)60015-8
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:Postoperative pancreatic fistula (POPF) remains an important cause of morbidity and mortality after pancreaticoduodenectomy. Pancreaticogastrostomy (PG) as a reconstruction method after pancreaticoduodenectomy is a safe and optional surgical technique in decreasing the risk of POPF. In this study, ...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2017.01.003
更新日期:2018-05-01 00:00:00
abstract:PURPOSE:Sentinel lymph node biopsy (SLNB) has been rapidly adopted by surgical oncologists in the management of invasive breast cancer. This study reviews the Royal Australasian College of Surgeons (RACS) Sentinel Node versus Axillary Clearance (SNAC) trial and reports an interim analysis of the first 150 subjects. Oth...
journal_title:Asian journal of surgery
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/S1015-9584(09)60052-X
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVE:To compare robot-assisted surgery and conventional laparoscopy for gynecologic oncology regarding intra- and post-operative outcomes. METHODS:A retrospective study was performed on consecutive patients with gynecologic oncology from February 2014 to October 2017 at Gansu Provincial Hospital, China. Multivari...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2019.05.003
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To determine the efficacy of intracorpus spongiosum anaesthesia during minor procedures on the glans and anterior urethra in the outpatient clinic. METHODS:Sixty-nine consecutive male patients underwent various procedures on the glans penis or anterior urethra under intracorpus spongiosum anaesthesia, which ...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/s1015-9584(09)60361-4
更新日期:2005-10-01 00:00:00
abstract::Retroperitoneal cysts are rare, usually asymptomatic, lesions. We present the case of a 42-year-old woman with an asymptomatic abdominal mass. The mass excised at our district hospital was found in the retroperitoneum. Histologically, the cyst was lined with benign Mullerian-type epithelium. The classification, aetiol...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(09)60062-2
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To investigate the oncological and functional outcomes after partial nephrectomy for clinical stage T1 (cT1) renal cell carcinoma (RCC), and assess the association between excisional volume loss (EVL) and postoperative renal function. METHODS:We retrospectively reviewed 150 patients with cT1 RCC ...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2019.05.015
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Preoperative hypoalbuminemia is a well-known risk factor for anastomotic leakage after colorectal surgery, but the association between perioperative albumin level and anastomotic leakage has not been fully investigated in curative colorectal cancer (CRC) patients. METHODS:In total, 200 CRC patients (Stage I...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2016.07.009
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To compare the safety and efficacy of transurethral plasmakinetic resection of the prostate (PKRP) versus transvesical prostatectomy (TVP) in the treatment of large-volume benign prostatic hyperplasia (LV-BPH) (100-149 mL). METHODS:Ninety-nine BPH patients who had a prostate volume of 100-149 mL were divided...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2013.04.006
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:According to previous studies, low serum total cholesterol (TC) is associated with higher cancer incidence and mortality. However, the prognostic implications of preoperative TC in patients with gastric cancer (GC) remain to be determined. METHODS:A total of 1251 patients with GC, who underwent radical gast...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2020.08.014
更新日期:2021-01-01 00:00:00
abstract::Necrotizing fasciitis is a potentially life threatening, rapidly spreading polymicrobial infection rarely seen in the head and neck region. We present our experience of managing five patients with necrotizing fasciitis of head and neck at the Aga Khan University Hospital, Karachi, Pakistan. One patient had necrotizing...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::Parathyroid carcinoma is a rare disease of unknown etiology. This study presents a case of parathyroid carcinoma in a patient with tertiary hyperparathyroidism. Despite a successful kidney transplantation, the intact parathyroid hormone (iPTH) level of the patient was elevated consistently and could not be controlled ...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2013.01.007
更新日期:2016-10-01 00:00:00
abstract::Surgical smoke is the gaseous by-product formed during surgical procedures. Most surgeons, operating theatre staff and administrators are unaware of its potential health risks. Surgical smoke is produced by various surgical instruments including those used in electrocautery, lasers, ultrasonic scalpels, high speed dri...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(09)60403-6
更新日期:2009-10-01 00:00:00
abstract:AIM:To find out the potential benefit of bladder pressure (BP) measurement as a diagnostic tool for acute abdomen. BACKGROUND:Acute abdomen is one of the most important clinical entities among general surgical clinics. The diagnosis can be achieved by considering the patient's history, physical examination, laboratory...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(09)60006-3
更新日期:2009-01-01 00:00:00
abstract::Video-assisted thorascopic surgery (VATS) is a common technique for thoracic operations. Surgery with access via a single port has gradually become popular. We herein report the unusual case of a 53-year-old Japanese male patient whose chest X-rays revealed an abnormal shadow, which continued to increase in size. The ...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2011.08.006
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:This study investigated the effectiveness of unilateral nephrectomy in the treatment of renal hypertension in adults with an atrophic kidney, and set out to establish whether this is an appropriate mode of treatment for renal hypertension not otherwise controlled by antihypertensive drugs or other surgical pr...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(08)60083-4
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVE:Bladder catheterisation is a routine part of major abdominal surgery. Transurethral catheterisation is the most common method of bladder drainage but is also notorious for its discomfort and increased risk of urinary tract infection. The present study aimed to establish patient satisfaction with transurethral...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(10)60006-1
更新日期:2010-01-01 00:00:00
abstract::Although true hermaphrodite is uncommon, it has been reported in more than 400 individuals. Tumours arising in the gonads of true hermaphrodite is a very rare finding and only very few cases have been reported in the literature. We report a case of a 35-year-old phenotype man with bilateral undescended testis with lum...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(09)60136-6
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Written informed consent forms (ICFs) are important for ensuring that physicians disclose core information to patients to help them autonomously decide about treatment and for providing substantial evidence for the surgeon in case of a legal dispute. This paper aims to assess the legal and ethical appropriat...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2019.08.008
更新日期:2020-03-01 00:00:00
abstract::Chylous ascites specifically after anterior resection for rectal cancer has not been documented in the literature thus far. All previously reported postoperative chylous ascites developed in other types of malignancies and were diagnosed within a few days of surgery. However, the patient we report had symptoms 2 years...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/S1015-9584(09)60295-5
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:Patients on hemodialysis (HD) who undergo abdominal surgery for gastrointestinal disease are at increased risk of postoperative complications. In this study, we retrospectively investigated the predictors of postoperative complications among such patients. METHODS:The study group comprised 36 HD p...
journal_title:Asian journal of surgery
pub_type: 杂志文章
doi:10.1016/j.asjsur.2015.03.013
更新日期:2016-10-01 00:00:00