Abstract：
BACKGROUND:Several meta-analyses have been performed to compare unilateral percutaneous kyphoplasty (PKP) and bilateral PKP in the treatment of osteoporotic vertebral compression fractures (OVCFs), but inconsistencies in the results have led to questions as to which technique is preferable. OBJECTIVE:This study was designed to clarify the benefits and disadvantages of unilateral PKP versus bilateral PKP as found in numerous discordant meta-analyses and thereby present surgical treatment recommendations for OVCFs considering the current best evidence. STUDY DESIGN:Systematic review/Meta-analysis. METHODS:Meta-analyses on unilateral and bilateral PKP for OVCFs were included by searching Pubmed, Embase, and Cochrane library. Meta-analysis quality was assessed using Oxford Levels of Evidence and Assessment of Multiple Systematic Reviews (AMSTAR). The Jadad decision algorithm was used to identify the best evidence. RESULTS:Eight eligible meta-analyses were included, 7 of which were Level-II evidence and one was Level-III evidence. The AMSTAR scores varied from 7 to 8. The Jadad decision algorithm suggested that the best meta-analysis should be selected depending upon publication characteristics and methodology of primary studies, language restrictions, and whether data analysis was performed on individual patients. The best available evidence indicated that both unilateral and bilateral PKP could receive similar good clinical and radiological outcomes. However, without increasing the risk of complications, unilateral PKP required shorter surgical time and less cement volume, offering better pain relief and quality of life at post-operative short term follow-ups. LIMITATIONS:Primary studies had defects in their methodologies. CONCLUSIONS:Unilateral PKP appears to be superior to bilateral PKP in the treatment of OVCFs. KEY WORDS:Osteoporotic vertebral compression fractures, percutaneous kyphoplasty, meta-analysis.
journal_name
Pain Physicianjournal_title
Pain physicianauthors
Chen X,Guo W,Li Q,Ou Z,Lao Z,Liu Y,Zhu C,Han Z,Chu X,Cai Dsubject
Has Abstractpub_date
2018-07-01 00:00:00pages
327-336issue
4eissn
1533-3159issn
2150-1149journal_volume
21pub_type
杂志文章,meta分析相关文献
Pain Physician文献大全abstract：BACKGROUND:Chronic spinal pain is common along with numerous modalities of diagnostic and therapeutic interventions utilized, creating a health care crisis. Facet joint injections and epidural injections are the 2 most commonly utilized interventions in managing chronic spinal pain. While the literature addressing the ...
journal_title：Pain physician
pub_type： 临床试验,杂志文章
doi：
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND:Epidural injection is performed for treatment of back and radicular pain in patients with lumbosacral disc herniation (LDH). Steroids are usually administered to effectively remove inflammatory mediators, and local anesthetics or saline also contribute to pain reduction by washing out chemical mediators or b...
journal_title：Pain physician
pub_type： 杂志文章,meta分析
doi：
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:Post lumbar surgery syndrome is common and often results in chronic, persistent pain and disability, which can lead to multiple interventions. After failure of conservative treatment, either surgical treatment or a nonsurgical modality of treatment such as epidural injections, percutaneous adhesiolysis are o...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2019-07-01 00:00:00
abstract：:When spinal injections are performed, a needle is placed in or around the spine making the risk of complications unavoidable. Spinal structures or adjacent organs are at risk for direct needle trauma, infection, hematoma, hemorrhage, nerve damage, stroke, allergic reaction, or spinal anesthesia with cardiorespiratory ...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
abstract：:Although percutaneous endoscopic lumbar discectomy (PELD) is an effective treatment for herniated discs, its application in a disc with extensive migration is still challenging. As such, epiduroscopic laser neural decompression (ELND) provides a new view of the epidural space as well as an alternative treatment for a ...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:Before long-term intrathecal analgesic therapy is initiated, patients often undergo a spinal analgesia trial. Ziconotide is a nonopioid intrathecal analgesic used to manage severe chronic pain, and a variety of methods have been used to trial ziconotide. OBJECTIVES:The purpose of this review is to compare a...
journal_title：Pain physician
pub_type： 杂志文章,评审
doi：
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:While most trials of thoracic paravertebral nerve blocks (TPVB) for breast surgery show benefit, their effect on postoperative pain intensity, opioid consumption, and prevention of chronic postsurgical pain varies substantially across studies. Variability may result from use of different drugs and techniques...
journal_title：Pain physician
pub_type： 杂志文章,meta分析,评审
doi：
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:Recently, several studies suggested that radiofrequency (RF) ablation of the genicular nerves is a safe and effective therapeutic procedure for intractable pain associated with chronic knee osteoarthritis (OA). Diagnostic genicular nerve block (GNB) with local anesthetic has been generally conducted before m...
journal_title：Pain physician
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2018-01-01 00:00:00
abstract：INTRODUCTION:Postdural puncture headache (PDPH) is a known complication of diagnostic lumbar puncture. Multiple factors including needle size, type, and needle bevel orientation, have been postulated to contribute to the development of PDPH. The presentation of PDPH tends to have classic symptoms that include a postura...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:Peripheral neuromodulation is often used as chronic neuropathic pain treatment. Percutaneous electrical nerve stimulation (PENS) is generally utilized with several probes at the same time and repeated treatments. OBJECTIVES:Evaluate the short- and long-term efficacy of a single probe and single shot PENS ap...
journal_title：Pain physician
pub_type： 杂志文章,多中心研究
doi：
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:Recently, transforaminal balloon adhesiolysis was introduced to manage patients with chronic radicular pain occurring with or without low back pain. However, the factors associated with successful responses to transforaminal balloon adhesiolysis are not known. OBJECTIVE:To evaluate the factors associated wi...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2017-09-01 00:00:00
abstract：BACKGROUND:Neuropathic pain (NP) is a major public health problem worldwide. Because of the unclear mechanism of NP, its treatment is one of the most difficult medical problems. As a targeted, noninvasive, safe therapy, pulsed radiofrequency (PRF) provides a new method for the treatment of NP; however, its effect on th...
journal_title：Pain physician
pub_type： 杂志文章,meta分析
doi：
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:Opioids are used extensively for chronic pain management in the United States. The frequency of opioid use prior to presenting to interventional pain management settings and in interventional pain management settings has been shown to be above 90%. Opioid abuse has been demonstrated in 9% to 41% of patients ...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2006-07-01 00:00:00
abstract：:Cervical interlaminar epidural steroid injections (ESIs) are commonly performed as one part of a multi-modal analgesic regimen in the management of upper extremity radicular pain. Spinal epidural hematoma (SEH) is a rare complication with a reported incidence ranging from 1.38 in 10,000 to 1 in 190,000 epidurals. Curr...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2014-05-01 00:00:00
abstract：BACKGROUND:Up until now, the optimal strategy for postoperative pain management after total knee arthroplasty (TKA) remains to be elucidated. OBJECTIVE:The current investigation aimed to examine the analgesic efficacy and the opioid sparing effects of intravenous parecoxib in combination with continuous femoral blocka...
journal_title：Pain physician
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:Osteonecrosis, also known as avascular necrosis, of the femoral head is a debilitating disorder that commonly affects 30- to 50-year-old individuals. Currently, definitive treatment is limited to total hip replacement. However, recent studies have demonstrated bone regeneration in the femoral head after the ...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：:This study was designed to investigate radiation exposure to a physician performing fluoroscopically guided caudal epidural steroid injections. The prospective study design included 100 consecutive fluoroscopically guided caudal epidural steroid injections performed on patients with radiculitis from either herniated n...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2001-10-01 00:00:00
abstract：BACKGROUND:Lumbar stenosis is characterized by a narrowing of the spinal canal in association with progressive degenerative changes in the lumbar spine and surrounding structures, including hypertrophy of the ligamentum flavum (LF). OBJECTIVES:The aim of this study was to examine the usefulness of endoscope-assisted i...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:Corticosteroids have been used for the past 70 years in the treatment of various musculoskeletal conditions. This includes its use for joint pain such as rheumatoid arthritis and osteoarthritis. OBJECTIVES:A narrative review of the literature from its initial discovery to the present day to summarize the re...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2021-01-01 00:00:00
abstract：:The Department for Health and Human Services (HHS) has issued the final rule that will govern electronic exchanges of financial and administrative information in the health care industry. About 400 different formats currently exist for electronic health care claims. Once compliance with this rule is required (October ...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2000-10-01 00:00:00
abstract：:Propofol is a common induction agent that is utilized worldwide in the field of anesthesiology. In recent years, its potential therapeutic role in a variety of patient states has been demonstrated. Controversy exists regarding Propofol mediated analgesic and antihyperalgesic properties. Recent studies have suggested a...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：UNLABELLED:Complex regional pain syndrome (CRPS) presents a therapeutic challenge due to its many presentations and multifaceted pathophysiology. There is no approved treatment algorithm and clinical interventions are often applied empirically. In cases of CRPS where symptoms are localized to an extremity, a targeted t...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:Post-dural puncture headache (PDPH) is the most common complication of procedures in which the dura mater is penetrated. OBJECTIVES:To evaluate the effectiveness of caudal saline injections as a therapeutic approach for handling post-dural puncture headache. STUDY DESIGN:Prospective observational study bet...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2011-05-01 00:00:00
abstract：BACKGROUND:Opioids are the mainstay of pain management for acute postsurgical pain. Oral oxycodone is an opioid that can provide effective acute postoperative pain relief. OBJECTIVES:To evaluate the use of oral oxycodone for acute postoperative pain management. STUDY DESIGN:This is a narrative review based on publish...
journal_title：Pain physician
pub_type： 杂志文章,评审
doi：
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:Chronic lumbosacral radicular pain is a common source of radiating leg pain seen in pain management patients. These patients are frequently managed conservatively with multiple modalities including medications, physical therapy, and epidural steroid injections. Radiofrequency has been used to treat chronic r...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND:The rapid increase in the prevalence of chronic pain and disability, and the explosion of interventional pain management associated health care costs are a major concern for our community. Further, the increasing utilization of numerous modalities of treatments in managing chronic pain, continue to escalate ...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Glucocorticoids adversely affect bone mineral density (BMD) and increase the risk of fracture. Yet, the cause-and-effect relationship between epidural steroid injection (ESI) and BMD has not been thoroughly investigated, and available results are inconsistent. This is probably a consequence of differences in...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:It is important to understand the anatomical relationship between the medial and lateral branches of superficial radial nerve (SRN) and the first dorsal compartment to prevent and minimize possible injury to these nerves during various procedures around the tip of radial styloid process (RSP). OBJECTIVE:To ...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Accumulating experimental and clinical evidence supports the hypothesis that complex regional pain syndrome type I (CRPS-I) may be a small fiber neuropathy. OBJECTIVES:To evaluate the use of commercially available standard biopsy methods to detect intradermal axon pathology in CRPS-I, and to ascertain if th...
journal_title：Pain physician
pub_type： 杂志文章
doi：
更新日期：2012-05-01 00:00:00
abstract：BACKGROUND:Lumbar provocation discography is a controversial diagnostic test. Currently, there is a concern that the test has an unacceptably high false-positive rate. STUDY DESIGN:Systematic review and meta-analysis. OBJECTIVE:To perform a systematic review of lumbar discography studies in asymptomatic subjects and ...
journal_title：Pain physician
pub_type： 杂志文章,评审
doi：
更新日期：2008-07-01 00:00:00
