Abstract:
BACKGROUND:Chronic smokers show differences in pain sensitivity compared to healthy non-smokers. Yet, no study to date has examined whether smoker status has an effect on postoperative pain. OBJECTIVE:We aim to examine a possible correlation between preoperative smoking and postoperative opioid dose based on the hypothesis that smokers would use higher doses of opioids to manage increased postoperative pain. STUDY DESIGN:A retrospective observational cohort study. SETTING:The National Cancer Center in Korea. METHODS:We examined medical record data for patients who had undergone curative resection for either lung or esophageal cancer (lobectomy or bilobectomy for lung cancer or an Ivor Lewis operation for esophageal cancer) between January 1, 2006 and December 31, 2010. We examined the correlation between the total preoperative average number of packs per day multiplied by years of cigarette smoking (pack-years) and morphine equivalent daily doses administered to patients after surgery, considering each type of cancer both individually and together. Partial correlation and regression analyses were performed to determine the causality of a possible relationship between pack-years of cigarette smoking and postoperative opioid dose. RESULTS:A total of 1,129 patients (871 patients with lung cancer and 258 patients with esophageal cancer) were included in the final analysis. There was no significant correlation between total pack-years of cigarette smoking and postoperative opioid dose for lung cancer, esophageal cancer, or both cancer types combined (r = 0.042, -0.012, and 0.037, respectively). In the analysis of both cancer types combined, video-assisted thoracic surgery (VATS) was associated with an 11.1% decrease in opioid dose (β = -0.111, P = 0.003) and epidural analgesia was associated with a 7.2% increase in opioid dose (β = 0.072, P = 0.042). LIMITATIONS:The retrospective design of this study is a limitation. CONCLUSION:Our study did not observe a correlation between preoperative smoking and postoperative opioid dose in patients with lung or esophageal cancer. KEY WORDS:Smoking, postoperative pain, opioid, lung cancer, esophageal cancer, analgesia.
journal_name
Pain Physicianjournal_title
Pain physicianauthors
Oh TK,Jeon JH,Lee JM,Kim MS,Kim JH,Lee SJ,Eom Wsubject
Has Abstractpub_date
2018-01-01 00:00:00pages
E49-E55issue
1eissn
1533-3159issn
2150-1149journal_volume
21pub_type
杂志文章相关文献
Pain Physician文献大全abstract::This study was designed to investigate radiation exposure to a physician performing fluoroscopically guided caudal epidural steroid injections. The prospective study design included 100 consecutive fluoroscopically guided caudal epidural steroid injections performed on patients with radiculitis from either herniated n...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2001-10-01 00:00:00
abstract:BACKGROUND:Hypersensitivity of the central nervous system to environmental and chemical stimuli is a clinical feature of central sensitization mechanisms that can be assessed with the central sensitization inventory (CSI). OBJECTIVE:The aim was to determine prevalence rate of this feature and explore the treatment-, p...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:The trends of the expenditures of facet joint interventions have not been specifically assessed in the fee-for-service (FFS) Medicare population since 2009. OBJECTIVE:The objective of this investigation is to assess trends of expenditures and utilization of facet joint interventions in FFS Medicare populati...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2020-05-01 00:00:00
abstract::Complex regional pain syndrome (CRPS) is a chronic, debilitating, neuropathic pain condition which is often misdiagnosed, difficult to manage, and lacks proven methods for remission. Most available methods provide some relief to a small percentage of patients. Recent FDA approval and superiority of the Nevro Senza 10-...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Chronic low back pain (CLBP) incurs huge costs owing to increased healthcare expenditure, disability, insurance, and work absenteeism. Opioid analgesics are commonly used for the management of CLBP. OBJECTIVE:To compare and rank the opioids used in the management of CLBP, in terms of efficacy and safety. S...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2021-01-01 00:00:00
abstract::Practice guidelines are systematically developed statements to assist practitioners and patients in making decisions about appropriate health care for specific clinical circumstances. Clinical practice guidelines present statements of best practice based on a thorough evaluation of the evidence from published studies ...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2009-07-01 00:00:00
abstract:BACKGROUND:Interventional pain physicians commonly encounter patients with a treatment refractory "chronic pain syndrome". Such patients have a chronically painful medical disorder that is complicated by a number of psychosocial factors, including psychiatric and substance use disorders, physical deconditioning, depend...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:Postherpetic neuralgia (PHN) is a neuropathic pain that causes a reduction in patients' quality of life. There are many topical drugs for PHN, including topical lidocaine patch, topical application of capsaicin, and others. OBJECTIVES:This study aims to compare the efficacy and safety of topical drugs for P...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Elderly patients in general exhibit a higher incidence of chronic and neuropathic pain conditions. This group poses a particular clinical challenge due to age-related pharmacokinetic and pharmacodynamic issues, comorbid conditions, and polypharmacy, as well as frailty and cognitive decline. Poor control of p...
journal_title:Pain physician
pub_type: 杂志文章,评审
doi:
更新日期:2015-09-01 00:00:00
abstract::This study was designed to evaluate psychological status of 150 individuals; 50 without chronic pain and without psychotherapeutic drug therapy, Group I or control group; 50 patients with chronic pain, Group II, chronic pain group with involvement of one region; and 50 chronic pain patients with involvement of two or ...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:Symptomatic lumbar spinal stenosis (LSS) patients often suffer from multiple etiologies, and patient symptoms must be differentiated and identified as either neurogenic claudication, radicular pain, or both. The most common symptom associated with LSS is neurogenic claudication, which has been reported to oc...
journal_title:Pain physician
pub_type: 临床试验,杂志文章
doi:
更新日期:2012-11-01 00:00:00
abstract::Appropriate documentation, billing and coding in interventional pain practice is a crucial issue with a wide arena of regulatory reforms. There have been reports of billions of dollars in losses in health care fraud. Office of Inspector General reports a massive war on health fraud. Substantial savings from prepayment...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:Conventional percutaneous endoscopic lumbar discectomy (PELD) with an "inside-outside" technique has 4.3% - 10.3% surgical failure rate, especially in central herniated discs (HDs), migrated HDs, and axillary type HDs. PELD with foraminoplasty has been used for complex HDs. Percutaneous lumbar foraminoplasty...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2017-01-01 00:00:00
abstract::Chronic low back pain secondary to involvement of the facet joints is a common problem. Facet joints have been recognized as potential sources of back pain since 1911. Multiple authors have described distributions of pain patterns of facet joint pain. The facet joints are paired diarthrodial articulations between the ...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::Zygapophysial or facet joints have been implicated as cause of low back, mid back, upper back and neck pain with referred pain. Cervical, thoracic and lumbar facet joints are innervated by the medial branches of the dorsal rami. Zygapophysial (facet) joints have been implicated as the source of chronic pain in 15% to ...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Understanding the mechanisms of long-standing musculoskeletal pain and adaptations in response to physical rehabilitation is important for developing optimal treatment strategies. The influence of central adaptations of pain perception in response to rehabilitation of musculoskeletal pain remains unclear. O...
journal_title:Pain physician
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Postherpetic neuralgia (PHN) is often refractory to existing treatments. Pulsed radiofrequency (PRF) is known to be effective for treating neuropathic pain. In common, the targets of PRF treatment were the segmental dorsal root ganglion (DRG) neurons responsible for the pain. A potential complication that ca...
journal_title:Pain physician
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2013-01-01 00:00:00
abstract::Spondylodiscitis is an unusual but important cause of back pain. Patients with spinal infections typically present with severe sharp aching pain, malaise, fever, and percussion tenderness over the affected area. Early identification of the responsible organism is essential for adequate and prompt treatment. Fungal spo...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2004-04-01 00:00:00
abstract::This a unique case of severe scapular pain following unintentional epidural space air injection during epidural steroid injection.A 70-year-old woman presented for a fluoroscopically guided C7-T1 interlaminar epidural steroid injection. Three injection attempts were made using the loss of resistance with air technique...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2016-03-01 00:00:00
abstract::Propofol is a common induction agent that is utilized worldwide in the field of anesthesiology. In recent years, its potential therapeutic role in a variety of patient states has been demonstrated. Controversy exists regarding Propofol mediated analgesic and antihyperalgesic properties. Recent studies have suggested a...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Epidural injection of corticosteroids is one of the most commonly used interventions in managing chronic spinal pain. However, there has been a lack of well-designed randomized, controlled studies to determine the effectiveness of epidural injections. Consequently, debate continues as to the value of epidura...
journal_title:Pain physician
pub_type: 杂志文章,评审
doi:
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Pain arising from the lumbar facet joints is a common cause of axial back pain in adults. Radiofrequency neurotomy (RFN) of the medial branches of the spinal dorsal rami has been used as a treatment option. The most common side effect is transient, localized, burning, neuritic-type pain, termed post-neurotom...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Compared to an abundance of data on surgical techniques for degenerative spine conditions and the outcomes thereof, little is available to guide optimal perioperative pain management after spinal surgery. The aim of this study was to survey patterns of perioperative pain management after spinal surgery and t...
journal_title:Pain physician
pub_type: 杂志文章,多中心研究
doi:
更新日期:2013-05-01 00:00:00
abstract::In the United States, millions of Americans are affected by chronic pain, which adds heavily to national rates of morbidity, mortality, and disability, with an ever-increasing prevalence. According to a 2011 report titled Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research...
journal_title:Pain physician
pub_type: 杂志文章,评审
doi:
更新日期:2013-05-01 00:00:00
abstract::Pain following thoracotomy is of moderate to severe nature. Management of thoracotomy pain is a challenging task. Post thoracotomy pain has acute effects in the post operative period by affecting respiratory mechanics, which increases the morbidity. Poorly controlled thoracotomy pain in the acute phase may also lead t...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Opioid misuse and abuse occurring in association with the treatment of chronic non-cancer pain are not new phenomena, but their increasing prevalence in recent years is unprecedented. Advancements in pharmaceutical technologies have provided opioid-related drugs, which lack the pure mu agonist activity chara...
journal_title:Pain physician
pub_type: 杂志文章,评审
doi:
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Discography has been widely used in the lumbar and cervical spine as a diagnostic tool to identify sources of discogenic pain that may be amenable to surgical treatment. Discography in the cervical spine is currently performed without the benefit of pressure monitoring, and corresponding pressure parameters ...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2005-04-01 00:00:00
abstract::Pudendal neuralgia is a chronic neuropathic pelvic pain that is often misdiagnosed and inappropriately treated. The Nantes criteria provide a basis for the diagnosis of pudendal neuralgia due to pudendal nerve entrapment. The 5 essential diagnostic criteria are pain situated in the anatomical territory of the pudendal...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Chronic lumbosacral radicular pain is a common source of radiating leg pain seen in pain management patients. These patients are frequently managed conservatively with multiple modalities including medications, physical therapy, and epidural steroid injections. Radiofrequency has been used to treat chronic r...
journal_title:Pain physician
pub_type: 杂志文章
doi:
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Lumbar disc prolapse, protrusion, and extrusion are the most common causes of nerve root pain and surgical interventions, and yet they account for less than 5% of all low back problems. The typical rationale for traditional surgery is that it is an effort to provide more rapid relief of pain and disability. ...
journal_title:Pain physician
pub_type: 杂志文章,评审
doi:
更新日期:2013-04-01 00:00:00