Antibiotic Stewardship Programs in Nursing Homes: A Systematic Review.

Abstract:

INTRODUCTION:Antibiotic stewardship programs (ASPs) are coordinated interventions promoting the appropriate use of antibiotics to improve patient outcomes and reduce microbial resistance. These programs are now mandated in nursing homes (NHs) but it is unclear if these programs improve resident outcomes. This systematic review evaluated the current evidence regarding outcomes of ASPs in the NH. METHODS:PubMed, CINAHL, EMBASE, and the Cochrane Library were systematically searched for intervention trials of ASPs performed in NHs that evaluated final health outcomes (mortality and Clostridium difficile infections), healthcare utilization outcomes (emergency department visits and hospital admissions) and intermediate health outcomes (number of antibiotics prescribed, adherence to recommended guidelines). RESULTS:A total of 14 studies rated good or fair quality were included. Eight studies reported a reduction in antibiotic prescriptions. Ten found an increase in adherence to guidelines proposed by the studied ASP. None reported a statistically significant change in NH mortality rates, C. difficile infection rates, or hospitalizations. DISCUSSION:The limited research to date suggests that NH ASPs can affect intermediate health outcomes, but not key health outcomes or health care utilization. CONCLUSION:Larger trials evaluating more intensive interventions over longer durations may be needed to determine whether ASPs in NHs improve health outcomes as they have in hospitals.

journal_name

J Am Med Dir Assoc

authors

Feldstein D,Sloane PD,Feltner C

doi

10.1016/j.jamda.2017.06.019

subject

Has Abstract

pub_date

2018-02-01 00:00:00

pages

110-116

issue

2

eissn

1525-8610

issn

1538-9375

pii

S1525-8610(17)30362-6

journal_volume

19

pub_type

杂志文章
  • Low serum selenium level is associated with low muscle mass in the community-dwelling elderly.

    abstract:OBJECTIVES:Elderly persons with low muscle mass (LMM) or sarcopenia are prone to frailty and functional decline. This study aimed to investigate the relationship between serum selenium level and skeletal muscle mass in community-dwelling elderly. DESIGN:Cross-sectional observational study. SETTING AND PARTICIPANTS:A ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2014.06.014

    authors: Chen YL,Yang KC,Chang HH,Lee LT,Lu CW,Huang KC

    更新日期:2014-01-01 00:00:00

  • Risk of Nursing Home Admission After Femoral Fracture Compared With Stroke, Myocardial Infarction, and Pneumonia.

    abstract:OBJECTIVE:To analyze the burden of institutionalizations after femoral fracture and compare it with other "catastrophic" disease entities like stroke, myocardial infarction, or pneumonia. DESIGN/SETTING/PARTICIPANTS:Routine data of 414,000 hospitalized German patients aged 66 years and older were used to calculate ins...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2015.05.013

    authors: Rapp K,Rothenbacher D,Magaziner J,Becker C,Benzinger P,König HH,Jaensch A,Büchele G

    更新日期:2015-08-01 00:00:00

  • Social-Professional Networks in Long-Term Care Settings With People With Dementia: An Approach to Better Care? A Systematic Review.

    abstract:BACKGROUND:Dementia is a syndrome associated with stigma and social isolation. Forty-two percent of people with dementia in the United States and almost 40% in the United Kingdom live in assisted living and residential care facilities. Up to 90% of residents with dementia experience behavioral and psychological symptom...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,评审

    doi:10.1016/j.jamda.2015.11.015

    authors: Mitchell JI,Long JC,Braithwaite J,Brodaty H

    更新日期:2016-02-01 00:00:00

  • Depressive Symptoms and Frailty Among the Oldest Old: Evidence from a Multicenter Prospective Study.

    abstract:OBJECTIVE:There is a lack of studies disentangling whether changes in frailty are associated with subsequent changes in depressive symptoms or vice versa among the oldest old. Consequently, we aimed to disentangle this link. DESIGN:Three waves [follow-up (FU) wave 7 to FU wave 9; n = 423 individuals in the analytical ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2020.10.008

    authors: Hajek A,Brettschneider C,Mallon T,Lühmann D,Oey A,Wiese B,Weyerer S,Werle J,Fuchs A,Pentzek M,Röhr S,Luppa M,Mösch E,Weeg D,Heser K,Wagner M,Scherer M,Maier W,Riedel-Heller SG,König HH

    更新日期:2020-11-19 00:00:00

  • Asymptomatic bacteriuria in institutionalized elders in Israel.

    abstract:OBJECTIVES:To document the prevalence of asymptomatic bacteriuria in patients in one large long-term care facility, and describe clinical outcomes in initially bacteriuric and nonbacteriuric residents during prospective observation encompassing one year. METHODS:Patients enrolled in the study were residents of the Hai...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:

    authors: Raz R,Gronich D,Ben-Israel Y,Nicolle LE

    更新日期:2001-11-01 00:00:00

  • To What Extent Do Local Nursing Home Prescribing Patterns Relate to Psychotropic Prescribing in Assisted Living?

    abstract:OBJECTIVE:In nursing homes (NHs), psychoactive medication use has received notable attention, but less is known about prescribing in assisted living (AL). This study examined how antipsychotic and antianxiety medication prescribing in AL compares with NHs. DESIGN:Observational, cross-sectional AL data linked to public...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2020.11.037

    authors: Thomas K,Wretman CJ,Sloane PD,Carder P,Schwartz L,Beeber AS,Zimmerman S

    更新日期:2020-12-28 00:00:00

  • Community Coronavirus Disease 2019 Activity Level and Nursing Home Staff Testing for Active Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Indiana.

    abstract:OBJECTIVES:To assess whether using coronavirus disease 2019 (COVID-19) community activity level can accurately inform strategies for routine testing of facility staff for active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. DESIGN:Cross-sectional study. SETTING AND PARTICIPANTS:In total, 59,...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2020.10.038

    authors: Blackburn J,Weaver L,Cohen L,Menachemi N,Rusyniak DE,Unroe KT

    更新日期:2021-01-01 00:00:00

  • To evacuate or shelter in place: implications of universal hurricane evacuation policies on nursing home residents.

    abstract:OBJECTIVE:To examine the differential morbidity/mortality associated with evacuation versus sheltering in place for nursing home (NH) residents exposed to the 4 most recent Gulf hurricanes. METHODS:Observational study using Medicare claims and NH data sources. We compared the differential mortality/morbidity for long-...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2011.07.011

    authors: Dosa D,Hyer K,Thomas K,Swaminathan S,Feng Z,Brown L,Mor V

    更新日期:2012-02-01 00:00:00

  • Prediction of 6-month mortality in nursing home residents with advanced dementia: validity of a risk score.

    abstract:OBJECTIVE:Prognostic information is important for guiding palliative care planning for patients with dementia. We aim to validate a risk score that uses Minimum Data Set (MDS) to estimate 6-month mortality for nursing home residents with advanced dementia. DESIGN:Two cohort studies. SETTING:Six nursing homes in The N...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jamda.2007.05.004

    authors: van der Steen JT,Mitchell SL,Frijters DH,Kruse RL,Ribbe MW

    更新日期:2007-09-01 00:00:00

  • Is there a conflicted surrogate syndrome affecting quality of care in nursing homes?

    abstract::Is there a point at which family complaints about care cease to be constructive and become excessive and counterproductive? Do excessive complaint behaviors represent a "conflicted surrogate syndrome" that is indicative of psychopathology in the family member or family system? Can this psychopathology result in avoida...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2005.12.005

    authors: Kidder SW,Smith DA

    更新日期:2006-03-01 00:00:00

  • Advance care planning in nursing homes and assisted living communities.

    abstract:OBJECTIVES:To determine the prevalence and characteristics of advance care planning (ACP) among persons dying in long-term care (LTC) facilities, and to examine the relationship between respondent, facility, decedent, and family characteristics and ACP. DESIGN:After-death interviews of family members of decedents and ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2008.10.015

    authors: Daaleman TP,Williams CS,Preisser JS,Sloane PD,Biola H,Zimmerman S

    更新日期:2009-05-01 00:00:00

  • Determinants of living situation in a population of community-dwelling and assisted living-dwelling elders.

    abstract:OBJECTIVE:To determine what variables separate community-dwelling elders from assisted living-dwelling elders. DESIGN:Cross-sectional. SETTING:Community and assisted living facilities in Connecticut. PARTICIPANTS:114 individuals (77 community dwelling, 37 assisted living). ASSESSMENTS:Nutritional survey, 6-minute w...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2009.07.006

    authors: Avery E,Kleppinger A,Feinn R,Kenny AM

    更新日期:2010-02-01 00:00:00

  • Effects of Legal Access to Cannabis on Scheduled II-V Drug Prescriptions.

    abstract:BACKGROUND:Co-prescribing of scheduled drugs is endemic in the United Sates, increasing health risks to patients and the burden on healthcare systems. PURPOSE:We conducted a pragmatic historical cohort study to measure the effect of enrollment in a state-authorized United States' Medical Cannabis Program (MCP) on sche...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2017.07.017

    authors: Stith SS,Vigil JM,Adams IM,Reeve AP

    更新日期:2018-01-01 00:00:00

  • Insulinlike Growth Factor-1 and Its Binding Protein-3 Polymorphisms Predict Circulating IGF-1 Level and Appendicular Skeletal Muscle Mass in Chinese Elderly.

    abstract:BACKGROUND:Previous studies have demonstrated the polymorphisms of insulinlike growth factor-1 (IGF-1) and its binding protein-3 (IGFBP3) genes could affect the circulating IGF-1 level. Moreover, the serum IGF-1 level was correlated with muscle size. OBJECTIVES:This study aimed to explore the effect of polymorphisms o...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2014.11.015

    authors: Yang CW,Li TC,Li CI,Liu CS,Lin CH,Lin WY,Lin CC

    更新日期:2015-05-01 00:00:00

  • Using a Semi-Markov Model to Estimate Medicaid Cost Savings due to Minnesota's Return to Community Initiative.

    abstract:OBJECTIVES:To provide an estimate and level of uncertainty for Medicaid cost savings due to Minnesota's Return to Community Initiative (RTCI). DESIGN:Medicaid cost savings are estimated using a semi-Markov model and simulation approach. SETTING AND PARTICIPANTS:RTCI is a statewide program that assists private paying ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2020.07.016

    authors: Hass Z,Woodhouse M,Arling G

    更新日期:2020-08-28 00:00:00

  • Nursing home medical staff organization: correlates with quality indicators.

    abstract:OBJECTIVES:Little is known about the relationship between how medical care is organized and delivered in nursing homes. Taking a lead from the acute care arena, we hypothesize that nursing home medical staff organization (NHMSO) is an important predictor of clinical outcomes in the nursing home. METHODS:A total of 202...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2010.06.004

    authors: Katz PR,Karuza J,Lima J,Intrator O

    更新日期:2011-11-01 00:00:00

  • Feasibility of Perioperative eHealth Interventions for Older Surgical Patients: A Systematic Review.

    abstract:OBJECTIVES:EHealth interventions are increasingly being applied in perioperative care but have not been adequately studied for older surgical patients who could potentially benefit from them. Therefore, we evaluated the feasibility of perioperative eHealth interventions for this population. DESIGN:A systematic review ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,评审

    doi:10.1016/j.jamda.2020.05.035

    authors: Jonker LT,Haveman ME,de Bock GH,van Leeuwen BL,Lahr MMH

    更新日期:2020-12-01 00:00:00

  • Assessing dysfunctional behaviors in long-term care.

    abstract:OBJECTIVE:The Geriatric Level of Dysfunction Scale (GLDS) was developed to assess the intensity, frequency, and duration of 19 behavioral disturbance categories that can potentially interfere with long-term care. DESIGN:Secondary analysis of data collected from residents in long-term care facilities. PARTICIPANTS:Par...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2005.04.006

    authors: Clifford PA,Cipher DJ,Roper KD

    更新日期:2005-09-01 00:00:00

  • Cardiac and inflammatory biomarkers and in-hospital mortality in older medical patients.

    abstract:OBJECTIVES:Increasing evidence has mounted in recent years on the potential prognostic role of biomarkers out of cardiac-specific medical settings. We aimed to test whether cardiac and inflammatory biomarkers are independently associated with in-hospital mortality in older unselected medical inpatients undergoing stand...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2013.10.013

    authors: Comba M,Fonte G,Isaia G,Pricop L,Sciarrillo I,Michelis G,Bo M

    更新日期:2014-01-01 00:00:00

  • Polypharmacy Is Associated With Higher Frailty Risk in Older People: An 8-Year Longitudinal Cohort Study.

    abstract:OBJECTIVE:To investigate whether polypharmacy is associated with a higher incidence of frailty in a large cohort of North Americans during 8 years of follow-up. DESIGN:Longitudinal study, follow-up of 8 years. PARTICIPANTS:A total of 4402 individuals at high risk or having knee osteoarthritis free from frailty at bas...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2017.02.009

    authors: Veronese N,Stubbs B,Noale M,Solmi M,Pilotto A,Vaona A,Demurtas J,Mueller C,Huntley J,Crepaldi G,Maggi S

    更新日期:2017-07-01 00:00:00

  • Skin Failure: An Emerging Concept.

    abstract::Skin failure is an emerging concept that clarifies trends in clinical practice. Its recognition provides common nomenclature, opens research directions, and questions assumptions regarding pressure ulcers as a quality measure. Adoption of the term is a step toward uniform terminology in compliance with a value based p...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2016.03.014

    authors: Levine JM

    更新日期:2016-07-01 00:00:00

  • Quality of Care In Nursing Homes In Brazil.

    abstract:BACKGROUND:There is an increased demand for nursing homes (NHs) in middle-income countries such as Brazil. To monitor the quality of NHs, there is a need for reliable instruments to assess the extent to which the care provided meets the expectations and rights of residents and their families. PURPOSE:To evaluate the r...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2017.04.007

    authors: Fonseca de Oliveira WI,Saturno Hernández PJ,de Meneses Sousa K,da Silva G,da Silva Gama ZA

    更新日期:2017-07-01 00:00:00

  • Seasonal variation of deaths from fatal myocardial infarction, primary cardiac arrest, sudden cardiac death, and refractory congestive heart failure in older persons living in New York City.

    abstract:OBJECTIVE:To investigate if there is seasonal variation in cardiac deaths in older persons living in a nursing home in New York City. DESIGN:In a prospective study, the major clinical cause of death of all persons aged 60 years and older residing in a nursing home in New York City during a 15-year period was investiga...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:

    authors: Aronow WS,Ahn C

    更新日期:2000-11-01 00:00:00

  • The effect of a 12-month longitudinal long-term care rotation on knowledge and attitudes of internal medicine residents about geriatrics.

    abstract:OBJECTIVE:To determine if participation in a 12-month longitudinal long-term care (LTC) rotation resulted in improved knowledge and attitudes about geriatrics. DESIGN:Longitudinal study with paired measurements. SETTING:A community LTC facility and a university-affiliated, community-based internal medicine residency ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2006.05.009

    authors: Baum EE,Nelson KM

    更新日期:2007-02-01 00:00:00

  • Are standing order programs associated with influenza vaccination? - NNHS, 2004.

    abstract:BACKGROUND:Influenza vaccination coverage among nursing home residents has consistently been reported well below the Healthy People goals. We sought to determine if standing order programs (SOPs) in long-term care facilities are associated with greater influenza vaccination coverage among residents. METHODS:The Nation...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2009.12.091

    authors: Bardenheier BH,Shefer AM,Lu PJ,Remsburg RE,Marsteller JA

    更新日期:2010-11-01 00:00:00

  • Cross-Sectional and Longitudinal Associations Between Anemia and Frailty in Older Australian Men: The Concord Health and Aging in Men Project.

    abstract:BACKGROUND:Anemia and frailty are both common in older people and are associated with adverse health outcomes. There have been some cross-sectional studies of anemia and frailty but no longitudinal studies. The objectives of this study were to examine cross-sectional and longitudinal associations between anemia and fra...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2015.02.014

    authors: Hirani V,Naganathan V,Blyth F,Le Couteur DG,Kelly P,Handelsman DJ,Waite LM,Cumming RG

    更新日期:2015-07-01 00:00:00

  • Differentiating between lewy body dementia and Alzheimer's disease: a retrospective brain bank study.

    abstract::Recent research has shown that while Lewy body dementia. (LBD) may be the second most common form of dementia, it is difficult to confirm the disease before autopsy. Patients with LBD share many clinical signs and symptoms with patients diagnosed with Alzheimer's disease (AD), making it difficult to differentiate betw...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:

    authors: Knuffman J,Mohsin F,Feder J,Grossberg GT

    更新日期:2001-07-01 00:00:00

  • Risk of 30-Day Hospital Readmission Among Patients Discharged to Skilled Nursing Facilities: Development and Validation of a Risk-Prediction Model.

    abstract:OBJECTIVES:Patients discharged to a skilled nursing facility (SNF) for post-acute care have a high risk of hospital readmission. We aimed to develop and validate a risk-prediction model to prospectively quantify the risk of 30-day hospital readmission at the time of discharge to a SNF. DESIGN:Retrospective cohort stud...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2019.01.137

    authors: Chandra A,Rahman PA,Sneve A,McCoy RG,Thorsteinsdottir B,Chaudhry R,Storlie CB,Murphree DH Jr,Hanson GJ,Takahashi PY

    更新日期:2019-04-01 00:00:00

  • There Are No Nonresponders to Resistance-Type Exercise Training in Older Men and Women.

    abstract:OBJECTIVE:To assess the proposed prevalence of unresponsiveness of older men and women to augment lean body mass, muscle fiber size, muscle strength, and/or physical function following prolonged resistance-type exercise training. DESIGN/SETTING/PARTICIPANTS:A retrospective analysis of the adaptive response to 12 (n = ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2015.01.071

    authors: Churchward-Venne TA,Tieland M,Verdijk LB,Leenders M,Dirks ML,de Groot LC,van Loon LJ

    更新日期:2015-05-01 00:00:00

  • The Prevalence and Determinants of Using Traditional Chinese Medicine Among Middle-aged and Older Chinese Adults: Results From the China Health and Retirement Longitudinal Study.

    abstract:BACKGROUND:Although traditional Chinese medicine (TCM) is known as an integrative part of China's health care system, little is known on the prevalence and determinants of using TCM among the middle-aged and older Chinese population, especially among those with chronic conditions. METHODS:The nationwide survey data of...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2015.07.011

    authors: Liu T,Li X,Zou ZY,Li C

    更新日期:2015-11-01 00:00:00