Abstract：
BACKGROUND:Studies evaluating the association between bisphosphonates exposure and gastric cancer (GC) risk have reached inconsistent conclusions. The purpose of this updated meta-analysis was to assess whether bisphosphonates exposure were associated with an increased risk of GC. EVIDENCE ACQUISITION:We searched PubMed and Embase database and reviewed reference lists of retrieved articles to identify potential studies. Study selection and data abstraction were performed by two independent observers. We calculated pooled odds ratios and 95% CIs using the random effects models. EVIDENCE SYNTHESIS:The pooled relative risk showed no significant relationship between bisphosphonates exposure and GC risk (adjusted OR, 0.996, 95% CI, 0.860-1.152). The results were stable across stratified analysis on study design, sex, and duration of follow-up and geographic locations. We also investigated whether different types of bisphosphonates affected the pooled RR. Neither use of bisphosphonates, alendronate, nor etidronate was associated with GC risk. CONCLUSIONS:Our meta-analysis found no overall association between GC risk and bisphosphonates use. Further studies with large sample size and more covariate adjustments are needed.
journal_name
Minerva Medjournal_title
Minerva medicaauthors
Cai D,Qin J,Chen G,Feng W,Liu Jdoi
10.23736/S0026-4806.17.05055-8subject
Has Abstractpub_date
2017-10-01 00:00:00pages
464-472issue
5eissn
0026-4806issn
1827-1669pii
S0026-4806.17.05055-8journal_volume
108pub_type
杂志文章,评审相关文献
MINERVA MEDICA文献大全abstract：:A rare case of skin tumour, Merkel cell carcinoma, is reported. The histopathological and clinical features and surgical treatment are reported. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：:Following the observation of a high percentage of bacterial resistance to antibiotics, the mechanisms of the establishment and transmission of such resistances on an extra-chromosomal basis (R factors) are examined in detail. After noting that the increased incidence and spread of bacterial strains resistant to chemot...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1975-04-28 00:00:00
abstract：:Data reported in the literature on the existence of a circadian rhythm in PTH secretion are contradictory. In order to assess whether haematic PTH levels vary over a 24 hour period, the plasma levels of the hormone were evaluated at 6 different times during the day (12, 19, 24, 2, 4, 6 hours) in a group of 10 healthy ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1985-06-30 00:00:00
abstract：:Sixty cases of mammary secretion were studied using cytological examinations of the mammary secretion, traditional mammography, galactography and histological examination of bioptic samples. Comparison of the results produced by the different techniques highlighted the importance of galactography for the description o...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：:Left ventricular performance has been studied in 50 patients affected by primary polycythemia (P.V.) by determining systolic time intervals. 50 normal subjects were used as control group. All cases underwent a pharmacodynamic test with Amyl Nitrite. The results indicate that patients with P.V. present an abnormal beha...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1984-11-17 00:00:00
abstract：AIM:The aim of this analysis was to investigate the clinical characteristics and prognosis of patients with serum alpha-fetoproteinpositive gastric cancer (AFPGC) in order to improve the diagnosis and treatment. METHODS:A retrospective analysis was performed on the clinical characteristics and survival data of patient...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：2015-08-01 00:00:00
abstract：:After a short survey of the main tubercolinic cutaneous tests the Author dwells particularly upon Tine test and intradermoreaction. Then it's produced a casuistics about two groups of it's people with different stories as for B. Kock infection. The results obtained checking up the two groups with Tine test or with int...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1981-06-23 00:00:00
abstract：:The authors stress the actuality of percutaneous transhepatic cholangiography (P.T.C.) in differential diagnosis of jaundice, for absence of complications, low cost, simplicity of execution, and high percent of success. They derive their technique by Okuda et al., with some proper variations. Particular stress is plac...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1981-03-10 00:00:00
abstract：BACKGROUND:Skin tumours represent about 11% of all the malignant neoplasms and their frequency is increasing annually. Skin tumours (melanoma, basal and squamous cell carcinoma, etc.) can be used for a good screening activity, but in relation to breast or cervix uteri cancer needs to be better defined. A test on a popu...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：:Description of a clinical case diagnosed in the first hours of life in apparently well newborn. Diagnostic suspicion by palpation and transillumination. Absence of any subjective sign. Inspective symptom the light scrotal swelling. The neonate received an immediate surgical exploration with subsequent orchiectomy. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：:Although mammary pain is the most common reason prompting women to seek breast examination, it is considered to unimportant to be fully investigated and often treatment is extremely superficial. A projected investigation of the natural history of mammary pain through examination of the symptomatology of the commonest ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1985-01-28 00:00:00
abstract：:A synchronised programme consisting of VCR, CTX and MTX has been employed in 57 patients suffering fom lung carcinoma. Average survival was 10.6 months and overall tolerance was good. The best indications are intermittent long-term treatment and retreatment of patients with cancer recalcitrant to the same drugs. With ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1981-06-23 00:00:00
abstract：:Between December 1986 and December 1991, the Italian Cooperative Group on AIDS-related tumours documented 94 HIV related solid tumours. Of 21 germinal testicular tumours collected, ten were seminomas. Cervical carcinoma was observed observed in 28 IVDAs (intraepithelial in 8 and advanced, with rapid progression, in on...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：:A new technique for recording His bundle and right branch potential through the veins of the arm instead of by the femoral route is described. Recordings were carried out in 70 patients. In 10, His potential was recorded simultaneously by the femoral and brachial routes. Potentials proved to be similar as regards morp...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：:Platelets play an essential role in the pathogenesis of atherosclerosis; by impedance method we valued in whole blood platelet aggregation induced by collagen in 40 healthy subjects and in 40 type II and type IV hyperlipemic subjects. Meanwhile by radioimmunoassay we dosed thromboxane B2, a stable product of thromboxa...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1987-12-15 00:00:00
abstract：:Cough is an essential protective mechanism for the airways and lungs. Cough receptors are situated in the larynx and tracheobronchial tree, and are mediated by rapidly-adapting (irritant) Adelta fibers, although other receptors such as C-fiber receptors may contribute. Cough plasticity and interactions of cough pathwa...
journal_title：Minerva medica
pub_type： 杂志文章,评审
doi：
更新日期：2005-02-01 00:00:00
abstract：:Vascular access is the commonest invasive procedure in secondary care. Vascular access is understood as being access to the bloodstream of acute and chronic patients for diagnostic and therapeutic purposes such as blood sampling, vessel pressure monitoring, fluid infusions (blood transfusions, parenteral nutrition), p...
journal_title：Minerva medica
pub_type： 杂志文章
doi：10.23736/S0026-4806.18.05552-0
更新日期：2018-06-01 00:00:00
abstract：:Longitudinal research has shown that social failure to adjust can be prevented by early removal of ambiental factors encouraging pathological development of the Ego, and the detection and treatment of psychological tendencies towards the acquisition of deviant stimuli. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1975-09-12 00:00:00
abstract：:A psychological interview and the MHQ, Koch, Rorschach, TAT, Machover and family design psychological tests were conducted in pneumopathic patients. The results obtained with the MHQ were compared with those of the other tests with respect to the diagnosis of psychoneurosis. A perfect fit was observed. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1977-05-19 00:00:00
abstract：INTRODUCTION:HOX transcript antisense intergenic RNA (HOTAIR), a long non-coding RNA transcribed from the antisense strand of the HOXC gene locus, has been reported to be overexpressed in various carcinomas and is thought to be an indicator of poor prognosis. EVIDENCE ACQUISITION:We performed a meta-analysis using qua...
journal_title：Minerva medica
pub_type： 杂志文章,meta分析,评审
doi：
更新日期：2016-12-01 00:00:00
abstract：:In view of the present state of the Central ECG Department serving the "San Giovanni" group of hospitals in Turin and in consideration of the ever growing number of ECG's required daily, a reorganization of the department has become necessary. Such a reorganization must be based on the latest facilities offered by ele...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1976-10-01 00:00:00
abstract：:The most frequent causes of the feeling of "being a burden" in elderly people dependent on others due to chronic disabling pathologies are described. Often this feeling is the main, and sometimes the only reason for their isolation from the community. Suggestions are made for the removal of this feeling, which is felt...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1983-05-19 00:00:00
abstract：:As the use of cross-sectional imaging increases so does the incidence of asymptomatic pancreatic cysts. Pancreatic neoplastic cysts can be broadly grouped into mucinous lesions and solid pseudopapillary neoplasms, which have malignant potential and serous lesions, which have negligible malignant potential. Non-neoplas...
journal_title：Minerva medica
pub_type： 杂志文章,评审
doi：
更新日期：2014-10-01 00:00:00
abstract：:The Authors describe the clinical symptoms of malignant brain tumors emphasizing the relationship to raised intracranial pressure and to their different localizations. Problems involved in surgical therapy are described stating the limits and aims of conventional oncologic neurosurgery. The need for adequate pre and p...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1984-05-19 00:00:00
abstract：:A case of myelofibrosis developing in a peripheral leukaemia-type situation after splenectomy is presented. An examination of the hypotheses on the pathogenesis of myeloid metaplasia during myelofibrosis lead to the proposition that it may be caused by the "seeding" of medullary precursors in the spleen. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1983-10-13 00:00:00
abstract：AIM:The aim of this paper was to evaluate the effect of carbon dioxide (CO2) vs. air insufflation on post-endoscopic retrograde cholangiopancreatography (ERCP) abdominal pain and distension. In addition, we investigated the changes in the partial pressure of end-tidal CO2 (PetCO2) and the partial pressure of arterial C...
journal_title：Minerva medica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2011-08-01 00:00:00
abstract：:A case of Caroli's disease is presented. Stress is laid on the importance of transcutaneous cholangiography in the diagnosis of this morbid form, and the usefulness of both echotomography and computed tomography. The latter permits visualisation of the intra- and extrahepatic bile ducts and indicates the extent of the...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1984-06-30 00:00:00
abstract：:Hyperbaric oxygen may provoke lesions in various organs and tissues depending on the dose and application time. The toxic action mechanisms of oxygen are manifold. The pulmonary lesions that occur in mice submitted to various oxygen pressures are investigated. Anatomo-pathological examination revealed numerous alterat...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1976-05-12 00:00:00
abstract：:Recent progress in the field of neurochemical and neuropharmacological research into food intake control by the central nervous system is discussed. Particular emphasis is laid on the fundamental role played by the hypothalamus as the integration centre for the various afferent impulses and the processor of behavioura...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1984-07-31 00:00:00
abstract：:The new developed histamine H2-receptor antagonist ranitidine has proven to be a more potent and longer acting anti-secretory compound than cimetidine both after intravenous as well as oral administration. A daily dose of 200-300 mg ranitidine should correspond to 1.0-1.2 g cimetidine in the acute therapy of duodenal ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1981-10-20 00:00:00
