Abstract：
PURPOSE:There is a paucity of recent evidence regarding long-term urological and sexual outcomes following surgery for Hirschsprung disease (HD). We aimed to undertake a systematic review of all HD literature to define these outcomes. MATERIALS AND METHODS:A systematic literature search was conducted on studies from 1966 to 2014. Relevant articles were assessed for urological/sexual operative complications and functional sequelae. Studies were analysed in qualitative (Rangel score) and quantitative syntheses. RESULTS:Initially 257 reports were assessed, with 24 studies were eligible for inclusion (1972-2014). Mean study quality was 16.5 ± SD 4.8 (range 6-23), indicating overall fair/poor quality. Ten studies (1021 patients) reported operative complications, with ureteric/urethral/vaginal injury occurring in seven (0.7%) patients. In three studies, the primary outcome was urological functional assessment. From 17 studies, 52/2546 patients (2.0%) had reported urinary incontinence. In infants, absent spontaneous erections post-operatively was reported in 3/203 patients (1.5%, 5 studies); of these 3, parents did not note spontaneous erections pre-operatively either. In older patients, erectile dysfunction occurred in 6/498 (1.2%) males. Other sexual outcomes were reported in 10 studies, with 5/10 studies (416 patients) reporting no erectile dysfunction. In the other studies reports ranged from non-specified sexual dysfunction in one study to diverse sexual related problems in nine (7.8%) of their patients in another. CONCLUSIONS:Urological/sexual outcomes are rarely reported after HD surgery (24 studies over 42 years). Study quality is usually poor and a large proportion of the studies are more than 30 years old. In the majority of series it is unclear whether urological and sexual function impairments were not present or if they were not assessed. Prospective reporting of urological/sexual outcome is required, in particular in the era of new surgical techniques/approaches to HD.
journal_name
J Pediatr Uroljournal_title
Journal of pediatric urologyauthors
Versteegh HP,Johal NS,de Blaauw I,Stanton MPdoi
10.1016/j.jpurol.2016.07.019subject
Has Abstractpub_date
2016-12-01 00:00:00pages
352-360issue
6eissn
1477-5131issn
1873-4898pii
S1477-5131(16)30273-Xjournal_volume
12pub_type
杂志文章,评审abstract：INTRODUCTION:The use of administrative health data for research has prompted questions about its validity for this purpose. OBJECTIVE/STUDY DESIGN:The purpose of this study was to determine the concordance of Pediatric Health Information System (PHIS) perioperative antibiotic charges with the institution's medication ...
journal_title：Journal of pediatric urology
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更新日期：2017-04-01 00:00:00
abstract：OBJECTIVE:To assess the effectiveness and safety of intradetrusor injections of botulinum toxin type A (BTA) used to treat neurogenic detrusor overactivity in children. PATIENTS AND METHODS:We retrospectively reviewed the records of seven children treated at least once (7/7: one injection; 4/7: two and three injection...
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abstract：INTRODUCTION:Non-Wilms renal tumors represent a compelling subset of childhood renal tumors. However, their relative rarity renders accurate diagnosis, and therapy challenging which in some instance is inferred from their adult counterparts. OBJECTIVE:To describe the incidence and analyze the diagnostic challenges, th...
journal_title：Journal of pediatric urology
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更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:To investigate preoperative urinary flow patterns in hypospadic infants and compare them to those from normal infant boys. PATIENTS AND METHODS:Twenty-one boys (median age 14.0, range 12.8-21.6 months) referred for distal hypospadias surgery were compared to 19 healthy boys (median age 12.0, 9.2-19.8 months)...
journal_title：Journal of pediatric urology
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abstract：:This study demonstrates significantly improved bowel symptoms and satisfaction with Peristeen® use in pediatric patients with neurogenic bowel. The longer patients used Peristeen®, the greater the reduction in severity of their Neurogenic bowel and the greater the satisfaction with their bowel management. ...
journal_title：Journal of pediatric urology
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更新日期：2019-12-01 00:00:00
abstract：INTRODUCTION AND OBJECTIVE:Vesicoureteral reflux (VUR) has been associated with the development and progression of reflux nephropathy (RN). Management of VUR has become more conservative over time as therapies have not been reliably proven to prevent renal scarring. We sought to examine the incidence of end stage renal...
journal_title：Journal of pediatric urology
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doi：10.1016/j.jpurol.2020.06.023
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:Our aim was to assess the outcomes of infant robot-assisted laparoscopic (RAL) upper urinary tract reconstruction. MATERIALS AND METHODS:The medical records of all infants who underwent RAL upper urinary tract reconstruction were reviewed. Patients less than 1 year of age at surgery were included. Patient de...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2014.01.029
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVES:To undertake a baseline audit of our pediatric urodynamic service, identifying areas for improvement, and to determine whether clinical management was affected by urodynamic results. PATIENTS AND METHODS:All pediatric urodynamic studies during one calendar year were reviewed to determine the quality of repo...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2004.11.004
更新日期：2005-02-01 00:00:00
abstract：OBJECTIVE:Urolithiasis in children can cause considerable morbidity. Our aim was to evaluate the impact of intervention on the recoverability of kidney functions. MATERIALS AND METHODS:This prospective study included 93 children (66 boys and 27 girls) with median age of 3 years (range 0-14). Inclusion criteria were pr...
journal_title：Journal of pediatric urology
pub_type： 杂志文章,多中心研究
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更新日期：2011-06-01 00:00:00
abstract：OBJECTIVE:Our study was planned based on the hypothesis that epididymal anomalies may be more incidental and more severe in cases with bilateral undescended testicles compared to unilateral undescended cases. We also aimed to review the classifications of epididymal anomalies in the literature and to establish a simple...
journal_title：Journal of pediatric urology
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doi：10.1016/j.jpurol.2020.09.002
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abstract：:The Mitrofanoff procedure, first described in 1980, has been widely adopted for pediatric continent urinary diversion to increase patient independence and continence, decrease morbidity and infections, and preserve renal function. Although this principle employs the appendix primarily, numerous other tissue conduits h...
journal_title：Journal of pediatric urology
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doi：10.1016/j.jpurol.2005.02.001
更新日期：2005-10-01 00:00:00
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journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2018.12.001
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVES:It has been suggested that infants with dilating vesicoureteral reflux (VUR) often have lower urinary tract (LUT) dysfunction. Signs such as high voiding pressure levels, low bladder capacity and dyscoordination at voiding have previously been thought to be indicative of dysfunction. However, these findings ...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2014.08.010
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVE:Renal disorders can cause hypertension, but less is known about the influence of hydronephrosis on blood pressure. Hydronephrosis due to pelvo-ureteric junction obstruction (PUJO) is a fairly common condition (incidence in newborns of 0.5-1%). Although hypertensive effects of hydronephrosis have been suggeste...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2015.01.008
更新日期：2015-04-01 00:00:00
abstract：OBJECTIVE:Extravesical robot-assisted laparoscopic ureteral reimplantation (RALUR) is a popular alternative to open surgery. We report our experience with RALUR and evaluate clinical variables as predictors for failure. METHODS:We retrospectively evaluated the records of patients who underwent RALUR by a single surgeo...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2014.01.028
更新日期：2014-10-01 00:00:00
abstract：OBJECTIVE:Hydrocele and testicular edema caused by division of lymphatic vessels during varicocelectomy could lead to decrease in testicular function. In-vivo methylene blue mapping of testicular lymphatic vessels should prevent damage to the lymphatic system. MATERIALS AND METHODS:We retrospectively compared outcomes...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2007.09.005
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVE:Acquired recto-urethral fistula is an uncommon entity in children and occurs as a consequence of pelvic disorder, including trauma, iatrogenic injury, inflammatory bowel disease, pelvic neoplasm and infection. We have reviewed our experience with treatment of recto-urethral fistula and focussed on the outcome...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2009.03.001
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVE:To compare and evaluate dissection and Plastibell(®) circumcision techniques for the treatment of phimosis. METHODS:In 2006-2007, 125 children were submitted to circumcision by the same surgeon. The children were randomly divided into two groups (PD: Plastibell(®) and DC: dissection). In both groups the surg...
journal_title：Journal of pediatric urology
pub_type： 杂志文章,随机对照试验
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journal_title：Journal of pediatric urology
pub_type： 杂志文章,评审
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abstract：INTRODUCTION:Complications remain the top evaluation priority subsequent to hypospadias repair. Complications vary in further management, and usually require one or more reoperations. Patients and/or their parents concern not only with the success rate of reoperation, but also with the risk of numerous reoperations. O...
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abstract：BACKGROUND:Congenital adrenal hyperplasia (CAH) consists of a group of diseases characterized by an enzyme deficiency, particularly 21-hydroxylase deficiency. The condition may present in the simple virilizing form or in the salt-wasting form, with varying degrees of genital ambiguity. The non-heterosexual orientation ...
journal_title：Journal of pediatric urology
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pub_type： 杂志文章,多中心研究
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journal_title：Journal of pediatric urology
pub_type： 杂志文章,meta分析,评审
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更新日期：2012-06-01 00:00:00
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journal_title：Journal of pediatric urology
pub_type： 杂志文章
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abstract：AIM:Evaluation of cosmetic and functional outcome of single-stage exstrophy-epispadias complex repair in older children and those with previously failed repair. MATERIALS AND METHODS:This study comprised 15 children (12 boys and 3 girls) with classic bladder exstrophy and a mean age at repair of 8.6 months (range 2-24...
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abstract：INTRODUCTION:Successful surgical therapy for pediatric upper urinary tract calculi (UUTC) minimizes the need for repeat surgical interventions. However, staged procedures, whether planned or unplanned, are sometimes necessary. We assessed predictors of repeat intervention for children with UUTC using a nationwide admin...
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pub_type： 杂志文章,多中心研究
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更新日期：2018-06-01 00:00:00
