Abstract:
OBJECTIVES:Ischaemic preconditioning and postconditioning, which consist of one or a series of short ischaemic events. This study aimed to determine the efficiency of post-conditioning a flap in the minimisation of flap loss after a preconditioned skin flap. METHODS:The rats were divided into five groups: sham group, control group, pre-con group, post-con group, and pre + post-con group. On postoperative days 3 and 7, the entire flaps along with the margins of necrosis were traced onto transparent sheets. The areas of intact skin and tissue were recorded. RESULTS:The flap necrosis area and percentage of necrosis were calculated for each animal. The necrotic area percentage of the control group was found to be significantly higher than those of the other groups on Days 3 and 7 (p = 0.01 and p = 0.03, respectively). The necrotic area percentage of the pre-con group was significantly higher than the pre + post-con group on Day 7 (p = 0.01). VEGFR-3 expression was observed at a rate of more than 50% in the post-con group. The presence of a protective effect in the late period was separately investigated by immunohistochemical staining of VEGFR-3 in the proliferating vessels. The necrotic areas was reduced in the flaps of the pre-con, post-con, and pre + post-con groups and the combined preconditioning and postconditioning group has reduced necrotic area compared to preconditioning of the skin flap. CONCLUSION:The protective effect was observed on day 7 for combined ischaemic preconditioning and postconditioning. The presence of a protective effect in the late period was separately investigated by immunohistochemical staining of VEGFR-3 in the proliferating vessels.
journal_name
J Plast Surg Hand Surgjournal_title
Journal of plastic surgery and hand surgeryauthors
Akcal A,Sirvan SS,Karsidag S,Görgülü T,Akcal MA,Ozagari A,Tatlidede Sdoi
10.3109/2000656X.2016.1154468subject
Has Abstractpub_date
2016-08-01 00:00:00pages
233-8issue
4eissn
2000-656Xissn
2000-6764journal_volume
50pub_type
杂志文章abstract:BACKGROUND:Breast reduction is a procedure with a high rate of patient satisfaction. Many techniques can be used for this type of surgery; patient satisfaction can vary from one technique to another. The main aim of this study was to use Breast-Q for initial evaluation of patient satisfaction after breast reduction by ...
journal_title:Journal of plastic surgery and hand surgery
pub_type: 杂志文章
doi:10.1080/2000656X.2017.1291432
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abstract::Previous studies assessing the costs associated with two stage expander/implant (E/I) reconstruction rarely include the cost of complications. The purpose of this study is to analyze the complication costs associated with a single institution experience with immediate E/I reconstruction. All immediate two stage E/I re...
journal_title:Journal of plastic surgery and hand surgery
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doi:10.3109/2000656X.2014.970639
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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abstract:BACKGROUND:An ability to reliably assess excess skin after massive weight loss using well-described and transferrable methods is important. The aim of this trial was to evaluate inter-rater reliability of ptosis and circumference measurements in patients with excess skin after bariatric surgery. MATERIALS AND METHODS:...
journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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doi:10.3109/2000656X.2011.569198
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abstract:BACKGROUND:While Realdo Colombo from Cremona, Italy has, to date, been acknowledged to be the first to describe the possible absence of the palmaris longus muscle in men in 1559, the authors found this absence to be recorded in the first edition of "De Humani Corporis Fabrica Libri Septum" by Andreas Vesalius, publishe...
journal_title:Journal of plastic surgery and hand surgery
pub_type: 历史文章,杂志文章
doi:10.3109/2000656X.2015.1073156
更新日期:2016-01-01 00:00:00
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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doi:10.3109/2000656X.2013.819003
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journal_title:Journal of plastic surgery and hand surgery
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doi:10.3109/2000656X.2013.779801
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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journal_title:Journal of plastic surgery and hand surgery
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