Blood pro-oxidant/antioxidant balance in young men with class II obesity after 20 sessions of whole body cryostimulation: a preliminary study.

abstract：:Although the importance of glutathione in protection against oxidative stress is well recognized, the role of physiological levels of glutathione and other endogenous antioxidants in protecting against exercise-induced oxidative stress is less clear. We evaluated the role of glutathione and selected antioxidant enzyme...

journal_title：Redox report : communications in free radical research

authors： Laaksonen DE,Atalay M,Niskanen L,Uusitupa M,Hänninen O,Sen CK

更新日期：1999-01-01 00:00:00

abstract：:Smoking has been associated with a large number of diseases, in particular cancers. Among the many substances identified in tobacco smoke, reactive oxygen species (ROS) are major carcinogens. We have previously reported that exposure of mammalian cells to tobacco smoke induces the expression of stress proteins, as wel...

journal_title：Redox report : communications in free radical research

authors： Banzet N,François D,Polla BS

更新日期：1999-01-01 00:00:00

abstract：:From a panel of 24 alleged antioxidants the most suitable antioxidants (AO) for use with chemiluminescence (CL) experiments were determined. Superoxide dismutase (SOD), using luminol as the chemiluminescence probe (Lum-CL), was inhibitory only towards O2*- and not HO* or (1)O2. SOD was thus a suitable antioxidant for ...

journal_title：Redox report : communications in free radical research

authors： Oosthuizen MM,Greyling D

更新日期：1999-01-01 00:00:00

abstract：:The ADVIA (Bayer) haematological system differentiates leukocytes by their volume and their peroxidase (MPO and EPO) activity. It thus allows specific counting of the eosinophils and detection of totally EPO and MPO deficient individuals. EPO activity is determined by the coordinates of the eosinophil cluster on the o...

journal_title：Redox report : communications in free radical research

authors： Kutter D,Janecki J,Verstraeten L

更新日期：2000-01-01 00:00:00

abstract：:The 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulphonic acid) radical (ABTS(.+)) can be generated by the enzymatic system formed by hydrogen peroxide and horseradish peroxidase in an organic medium. The ABTS radical is easily generated in acidified ethanol medium in about 100 s with a stability of 1.7 x 10(-3) (-deltaab...

journal_title：Redox report : communications in free radical research

authors： Cano A,Acosta M,Arnao MB

更新日期：2000-01-01 00:00:00

abstract：:Reactive oxygen species (ROS) are frequently associated with cytotoxicity, often being described as damaging, harmful or toxic. It is generally assumed that, under pathological circumstances, ROS elicit wide-spread and random acts of oxidation. This passive attack of cellular components by ROS, in conditions where oxi...

journal_title：Redox report : communications in free radical research

authors： Carmody RJ,Cotter TG

更新日期：2001-01-01 00:00:00

abstract：:It has been suggested that sequestration of parasitized red blood cells might contribute to the pathogenesis of cerebral malaria (CM), by hypoxia causing either: (i) compensatory vasodilatation with a resultant increase in the brain volume; or (ii) enhancing cytokine-induced nitric oxide (NO) production via induction ...

journal_title：Redox report : communications in free radical research

authors： Sanni LA

更新日期：2001-01-01 00:00:00

abstract：:The aim of this study was to determine whether disulfides could serve as protective antioxidants for alpha-tocopherol or vice versa. The chosen reaction system was a co-oxidation of the model compound of alpha-tocopherol, 2,2,5,7,8-pentamethyl-6-chromanol (PMC), and diphenyl disulfide (1) by 3-chloroperoxybenzoic acid...

journal_title：Redox report : communications in free radical research

authors： Srikendari EW,Sunthomphanich S,Southwell-Keely PT

更新日期：2001-01-01 00:00:00

abstract：:The aim of this investigation was to compare an improved fluorometric method with an UV absorbance assay for their ability to monitor low density lipoprotein (LDL) modification by myeloperoxidase (MPO) and to evaluate determining factors influencing the modification of LDL. Using absorbance at 234 nm to study the kine...

journal_title：Redox report : communications in free radical research

authors： Jerlich A,Hammel M,Horakova L,Schaur RJ

更新日期：2001-01-01 00:00:00

abstract：:This study was undertaken to investigate the nitric oxide synthase (NOS) activity in the striatum following 6-hydroxydopamine (6-OHDA) induced neurodegeneration in rats. Constitutive NOS (cNOS) activity remained unaltered at 3, 7 and 14 days after lesion, while a 43% and 45% decrease was observed at 30 and 50 days, re...

journal_title：Redox report : communications in free radical research

authors： Barthwal MK,Srivastava N,Dikshit M

更新日期：2001-01-01 00:00:00

abstract：:We have determined that the MIN mouse, which is predisposed to adenomas of the small and large intestine, exhibits chronic inflammation characterized by the induction of haptoglobin (HP), as well as other acute phase proteins. Inflammation is initiated at about 40-70 days of age, and is maintained throughout the life ...

journal_title：Redox report : communications in free radical research

authors： Barbour KW,Davis T,White A,Baumann H,Berger FG

更新日期：2001-01-01 00:00:00

abstract：:Surgical stress is difficult to evaluate quantitatively. It has been reported that mitochondrial membrane potential (delta psi(m)) in the peripheral blood lymphocytes (PBLs) is decreased by surgical stress. Thioredoxin (TRX), a small protein with redox-active dithiol/disulfide in the active site, is induced by a varie...

journal_title：Redox report : communications in free radical research

authors： Sugawara K,Nakamura H,Kanai M,Iwata S,Kawai Y,Taki Y,Yodoi J,Takabayashi A

更新日期：2002-01-01 00:00:00

abstract：:The modification of low-density lipoprotein (LDL) by normal, myeloperoxidase (MPO)-deficient and NADPH oxidase-deficient granulocytes was investigated using the monoclonal antibody (mAb) OB/04, which was originally generated against copper-oxidized LDL. Incubation of LDL with normal granulocytes increased the reactivi...

journal_title：Redox report : communications in free radical research

authors： Gerber CE,Bruchelt G,Ledinski G,Greilberger J,Niethammer D,Jürgens G

更新日期：2002-01-01 00:00:00

abstract：:Oxygen free radicals have been proposed to be major causative agents in secondary brain damage in traumatic and ischemic brain injury. Edarabone (3-methyl-1-phenyl-2-pyrazolin-5-one), a powerful antioxidative radical scavenger, is the only drug currently available in clinical practice for the treatment of cerebral inf...

journal_title：Redox report : communications in free radical research

authors： Satoh K,Ikeda Y,Shioda S,Tobe T,Yoshikawa T

更新日期：2002-01-01 00:00:00

abstract：:Electrochemical analysis has been widely used to assess activities of reductant antioxidants, but the mechanistic factors that determine reducing ability and their corresponding correlations remain to be explored further. In the present paper, the reactivity of a selection of phenolic compounds in anodic oxidation was...

journal_title：Redox report : communications in free radical research

authors： Cheng Z,Ren J,Li Y,Chang W,Chen Z

更新日期：2002-01-01 00:00:00

abstract：:It has been suggested that reactive oxygen species (ROS) may be involved in the regulation of vascular tone. However, the nature of ROS effects on vascular sensitivity remains to be elucidated. The present study was designed to investigate the effects of ROS, especially 1O2, on neurotransmission at the sympathetic neu...

journal_title：Redox report : communications in free radical research

authors： Yoshino F,Shoji H,Lee MC

更新日期：2002-01-01 00:00:00

abstract：:Yeast cells were used as a model system to study the inter-relationship among free radicals, antioxidants and UV-induced cell damage. In particular, the effects of UV-radiation in newly isolated yeasts from the Antarctic have been studied. ...

journal_title：Redox report : communications in free radical research

authors： Tsimako M,Guffogg S,Thomas-Hall S,Watson K

更新日期：2002-01-01 00:00:00

abstract：:We investigated the radical scavenging activity of propolis by ESR spectroscopy using spin trapping method. In addition, we examined the influence of a diet of 2% propolis on mice under oxidative stress. At low concentrations, the methanolic extract of propolis exhibited strong scavenging activity in vitro towards bot...

journal_title：Redox report : communications in free radical research

authors： Ichikawa H,Satoh K,Tobe T,Yasuda I,Ushio F,Matsumoto K,Endo K,Ookubo C

更新日期：2002-01-01 00:00:00

abstract：:The anemia in beta-thalassemia major is caused by a combination of hemolysis and ineffective erythropoiesis, with the latter being more important. Studies of the underlying cause of the hemolysis have indicated that oxidant injury to circulating red blood cells (RBCs) was of critical importance, with evidence of oxida...

journal_title：Redox report : communications in free radical research

authors： Schrier SL,Centis F,Verneris M,Ma L,Angelucci E

更新日期：2003-01-01 00:00:00

abstract：:The production of nitrogen monoxide (NO(*)) contributes to defence mechanisms of the immune system to fight infectious agents like bacteria and protozoa. The respective gene producing the NO(*) has to be carefully regulated so that an overwhelming response kills the pathogen but does not harm the host. A strong increa...

journal_title：Redox report : communications in free radical research

authors： Kun JF

更新日期：2003-01-01 00:00:00

abstract：:Amifostine (2-[(3-aminopropyl)amino]ethane-thiol dihydrogen phosphate ester; WR-2721) is a radioprotective agent used clinically to minimize damage from radiation therapy to adjacent normal tissues. This inorganic thiophosphate requires dephosphorylation to produce the active, cell-permeant thiol metabolite, WR-1065. ...

journal_title：Redox report : communications in free radical research

authors： Yu Z,Eaton JW,Persson HL

更新日期：2003-01-01 00:00:00

abstract：:The present study was designed to investigate the possible effects of peroxynitrite (ONOO(-)) on the intracellular calcium concentration ([Ca(2+)](i)) of mesenteric arteriolar smooth muscle cells (ASMCs), and to reveal the underlying mechanisms by using fluorescence imaging analysis. The results showed that ONOO(-) co...

journal_title：Redox report : communications in free radical research

authors： Pan BX,Zhao GL,Huang XL,Zhao KS

更新日期：2004-01-01 00:00:00

abstract：:Probucol, a clinically used cholesterol lowering and antioxidant drug, was investigated for possible protection against lipid peroxidation and DNA damage induced by iron nitrilotriacetate (Fe-NTA) plus hydrogen peroxide (H2O2). Fe-NTA is a potent nephrotoxic agent and induces acute and subacute renal proximal tubular ...

journal_title：Redox report : communications in free radical research

authors： Iqbal M,Sharma SD,Okada S

更新日期：2004-01-01 00:00:00

abstract：:Quinolinic acid increased the generation of lipid peroxidation products by isolated rat brain microvessels in vitro. The effect was inhibited both by a specific NMDA receptor antagonist D-2-amino-5-phosphonovaleric acid and by reduced glutathione (GSH). Furthermore, quinolinic acid displaced specific binding of [(3)H]...

journal_title：Redox report : communications in free radical research

authors： St'astný F,Lisý V,Mares V,Lisá V,Balcar VJ,Santamaría A

更新日期：2004-01-01 00:00:00

abstract：:Some 80 years after its discovery, vitamin E has experienced a renaissance which is as surprising as it is trivial. Although vitamin E is essential for reproduction, in rats at least, and deficiency causes neurological disorders in humans, the main interest in the last decades has concentrated on its antioxidant funct...

journal_title：Redox report : communications in free radical research

authors： Pfluger P,Kluth D,Landes N,Bumke-Vogt C,Brigelius-Flohé R

更新日期：2004-01-01 00:00:00

abstract：:Singlet oxygen is regarded as contributing to the pathogenesis of various diseases including light-induced skin disorders and inflammatory response. In this study, the correlation between singlet oxygen quenching activity (SOQA) of human serum and blood biochemistry or life-style was evaluated. Healthy volunteers were...

journal_title：Redox report : communications in free radical research

authors： Kon T,Tanigawa T,Hayamizu K,Shen M,Tsuji T,Naito Y,Yoshikawa T

更新日期：2004-01-01 00:00:00

abstract：:Myoglobin (Mb) is a haem protein present in skeletal, cardiac and smooth muscle where it facilitates the transfer of O(2) from the extracellular matrix to the cell cytosol in a cycle termed 'facilitated O(2)-diffusion'. In addition, we showed recently that recombinant human Mb binds endothelium-derived relaxant factor...

journal_title：Redox report : communications in free radical research

authors： Rayner BS,Wu BJ,Raftery M,Stocker R,Witting PK

更新日期：2004-01-01 00:00:00

abstract：:We investigated the inhibitory effect of para-masticatory activity, namely biting, on restraint stress-induced oxidative stress. A blood brain barrier-permeable nitroxyl spin probe, 3-methoxycarbonyl-2,2,5,5,-tetramethylpyrrolidine-1-oxyl (MC-PROXYL), was administered to rats and L-band electron spin resonance (ESR) a...

journal_title：Redox report : communications in free radical research

authors： Miyake S,Sasaguri K,Hori N,Shoji H,Yoshino F,Miyazaki H,Anzai K,Ikota N,Ozawa T,Toyoda M,Sato S,Lee MC

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:To evaluate the possible influence of topotecan therapy on lipid peroxidation and antioxidant enzymes in rabbit liver tissue, the levels of thiobarbituric acid reactive substances (TBARS) and activities of the antioxidant enzymes superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT)...

journal_title：Redox report : communications in free radical research

authors： Kisa U,Caglayan O,Kacmaz M

更新日期：2005-01-01 00:00:00

abstract：:Ubiquinone is inhomogenously distributed in subcellular biomembranes. Apart from mitochondria, where ubiquinone has bioenergetic and pathophysiological functions, unusually high levels of ubiquinone have also been reported in Golgi vesicles and lysosomes. In lysosomes, the interior differs from other organelles in its...

journal_title：Redox report : communications in free radical research

authors： Nohl H,Gille L

更新日期：2005-01-01 00:00:00