Calcium-sensing receptor promotes calcium oxalate crystal adhesion and renal injury in Wistar rats by promoting ROS production and subsequent regulation of PS ectropion, OPN, KIM-1, and ERK expression.

abstract：:The objective of this study was to look for the occurrence of catastrophic antiphospholipid syndromes (APS) and to try to detect discriminating factors for predicting a worse prognosis, related to Lupus anticoagulant (LA) and antiphospholipid antibodies (aPL), in systemic lupus erythematosus (SLE) with main renal invo...

journal_title：Renal failure

authors： Stratta P,Canavese C,Ferrero S,Grill A,Salomone M,Schinco PC,Fusaro E,Montaruli B,Santi S,Piccoli G

更新日期：1999-01-01 00:00:00

abstract：:The differential diagnosis of acute renal failure (ARF) and chronic renal failure (CRF) may be possible by measuring urinary dipeptidase (Udpase) activity and serum creatinine (Scr) concentration. When the mass test of 246 individuals was examined on a 2-dimensional plot of Udpase (y-axis) versus Scr (x-axis) with the...

journal_title：Renal failure

authors： Lee SH,Kang BY,We JS,Park SK,Park HS

更新日期：1999-03-01 00:00:00

abstract：:The current investigation is the largest to date concerned with the assessment of the value of different urinary biomarkers to detect nephrotoxic effects in children exposed to cadmium and lead. A battery of tests which had proved valuable in previous studies on men and women where used, together with a number of more...

journal_title：Renal failure

authors： Price RG,Patel S,Chivers I,Milligan P,Taylor SA

更新日期：1999-05-01 00:00:00

abstract：:The aim of this study was to investigate the effects of known papillotoxins using cultures of human renal interstital medullary cells (hRMIC). The culture of hMIC was based on the primary culture of human renal medullary explants, selective detachment of interstitial cells and selective overgrowth of these cells in a ...

journal_title：Renal failure

authors： Whiting PH,Tisocki K,Hawksworth GM

更新日期：1999-05-01 00:00:00

abstract：:The acute effects of acetaminophen, a commonly used as analgesic drug, upon the urinary excretion of some proteins and enzymes as markers of kidney damage, was investigated. Patients with chronic glomerulonephritis (GN) and Balkan endemic nephropathy (BEN), having kidney vulnerable to toxic drugs, were enrolled in the...

journal_title：Renal failure

authors： Mitić-Zlatković M,Stefanović V

更新日期：1999-09-01 00:00:00

abstract：:Female Sprague-Dawley rats underwent right nephrectomy and 40 min left renal artery occlusion (RAO). After 15 min of reflow, polyethylene glycol 1000 (PEG1000) was infused to induce osmotic diuresis and to enable glomerular filtration rate (GFR) measurements. Urine was collected during a 90 min period, and the concent...

journal_title：Renal failure

authors： Druid H,Nilsson I,Rammer L,Skude G

更新日期：1999-11-01 00:00:00

abstract：:Calcium antagonists have a potential for beneficial effects on kidney function unrelated to their antihypertensive action. In this study we have investigated the efficacy of calcium antagonists compounds (verapamil, nifedipine and diltiazem) on reversible acute renal insufficiency, proteinuria and interstitial nephrit...

journal_title：Renal failure

authors： Martin A,Cuevas B,Escudero E,Nieto E,Cuevas P,Pascual J,Ortuño J,Orte L,Mampaso F

更新日期：2000-01-01 00:00:00

abstract：:We studied whether plasma endothelin (ET)-1 concentrations are altered in patients with septic shock who are undergoing hemodialysis and whether polymyxin B-immobilized fiber (PMX-F) treatment affects on these concentrations. Fifteen hemodialysis patients with septic shock treated with PMX-F (group A), 10 such patient...

journal_title：Renal failure

authors： Nakamura T,Ushiyama C,Suzuki S,Shoji H,Shimada N,Ebihara I,Koide H

更新日期：2000-03-01 00:00:00

abstract：:Rhabdomyolysis may account for about 10% of all cases of acute renal failure (ARF). This study was performed to explore the protective influence of proanthocyanidins from seeds of grape in an experimental model of myoglobinuric ARF. Rats were injected with 50% glycerol (8 mL/kg, im) followed immediately and daily in t...

journal_title：Renal failure

authors： Stefanovic V,Savic V,Vlahovic P,Cvetkovic T,Najman S,Mitic-Zlatkovic M

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Femoral, subclavian, and internal jugular veins access have been widely used for temporary vascular access for hemodialysis, but their use has been associated with a significant complication rate. We report in three selected hemodialysis patients with the procedure of direct peripheral venopuncture as tempor...

journal_title：Renal failure

authors： Chen YC,Fang JT,Chang CT,Chang MY

更新日期：2000-05-01 00:00:00

abstract：:Reactive oxygen species are generated during ischemia-reperfusion tissue injury. Oxidation of thymidine by hydroxyl radicals (HO*) causes formation of 5,6-dihydroxy-5,6-dihydrothymidine (thymidine glycol). Thymidine glycol excreted in urine can be used as a biomarker of oxidative DNA damage. The aim of this study was ...

journal_title：Renal failure

authors： Makropoulos W,Kocher K,Heintz B,Schwarz ER,Mertens PR,Stefanidis I

更新日期：2000-01-01 00:00:00

abstract：:Psychoactive drugs provide essential intervention in the care of transplant recipients, yet little is known of their interaction with immunosuppressants such as cyclosporin (CSA). Lithium (Li) is an invaluable drug for the treatment of manic disorders in organ transplant patients. As both these drugs are known to prod...

journal_title：Renal failure

authors： Tariq M,Morais C,Sobki S,Al Sulaiman M,Al Khader A

更新日期：2000-01-01 00:00:00

abstract：:Tubulointerstitial involvement is well recognized in systemic lupus erythematosus. The tubular dysfunction is usually latent and usually presents after diagnosis of systemic lupus erythematosus. We report a case presenting that she is well previously and initially diagnosed as periodic paralysis of hypokalemia at emer...

journal_title：Renal failure

authors： Fang JT,Chen YC

更新日期：2000-01-01 00:00:00

abstract：:The podocyte has diverse functions including glomerular filtration, biosynthesis and maintenance of the glomerular capillary architecture. It discharges these functions by virtue of a unique morphology, an intimate relationship with the capillary wall, and diverse synthetic and membrane specializations. Despite the co...

journal_title：Renal failure

authors： Schwartz MM

更新日期：2000-11-01 00:00:00

abstract：:Mildly elevated serum creatinine concentration was proposed to be a marker for increased risk of cardiovascular disease mortality. The aim of our prospective study was to evaluate a possible association between serum creatinine concentration and extent of coronary atherosclerosis together with conventional risk factor...

journal_title：Renal failure

authors： Cerne D,Kaplan-Pavlovcic S,Kranjec I,Jurgens G

更新日期：2000-11-01 00:00:00

abstract：:We have evaluated the potential of urinary uronic acid measurement as an early indicator in the development of renal papillary necrosis (RPN). Urinary uronic acid was quantified with a range of other urinary biochemical parameters in rats given multiple doses of N-phenylanthranilic acid (NPAA) or mefenamic acid (MFA),...

journal_title：Renal failure

authors： Nguyen TK,Obatomi DK,Bach PH

更新日期：2001-01-01 00:00:00

abstract：:We previously demonstrated that Opuntia megacantha leaves' extracts can reduce blood glucose levels in diabetes mellitus. For O. megacantha leaves' extracts to have potential in the management of diabetes mellitus, it is necessary to establish its detailed effects on renal function since diabetes is associated with re...

journal_title：Renal failure

authors： Bwititi PT,Machakaire T,Nhachi CB,Musabayane CT

更新日期：2001-03-01 00:00:00

abstract：:Continuous Renal Replacement Therapy (CRRT) indication is still discussed. We report our experience on 98 patients affected with Multiple Organ System Failure (MOSF) and renal failure (acute or chronic) requiring dialysis and timely treated by CRRT. Mortality after 5 days of ICU permanence was 60.2%; the remaining 39 ...

journal_title：Renal failure

authors： Splendiani G,Mazzarella V,Cipriani S,Zazzaro D,Casciani CU

更新日期：2001-03-01 00:00:00

abstract：:Aldo-keto reductases (AKRs) are a family of monomeric oxido-reductases with molecular weight ranging from 35-40 kDa and currently includes upwards of 60 members. They are expressed in a wide variety of tissues, where they catalyze the NADPH-dependent reduction of various aliphatic and aromatic aldehydes and ketones. T...

journal_title：Renal failure

authors： Wallner EI,Wada J,Tramonti G,Lin S,Srivastava SK,Kanwar YS

更新日期：2001-05-01 00:00:00

abstract：INTRODUCTION:Beta 2 microglobulin (beta2M) is filtered by the glomeruli and reabsorbed by the proximal tubular cells where it is metabolized. Its plasma concentration increases with decreasing renal function. AIM:To compare serum creatinine (Cr) and serum beta2M as markers of GFR. PATIENTS AND METHODS:In 160 adult pa...

journal_title：Renal failure

authors： Bianchi C,Donadio C,Tramonti G,Consani C,Lorusso P,Rossi G

更新日期：2001-05-01 00:00:00

abstract：:The clinical course of primary Focal Segmental Glomerulosclerosis (FSGS) is frequently complicated by nephrotic range proteinuria and progression to renal failure. The high recurrence rate of the disease in transplanted kidney suggests the hypothesis that such patients have a circulating factor that alters glomerular ...

journal_title：Renal failure

authors： Moriconi L,Lenti C,Puccini R,Pasquariello A,Rindi P,Batini V,Carraro M,Zennaro C

更新日期：2001-05-01 00:00:00

abstract：:In order to assess the effects of mycophenolate mofetil (MMF) on the development of adriamycin-induced nephropathy, the development of this nephropathy in rats treated with MMF was compared to that in non-treated animals (group ADR + V) over 28 weeks. At weeks 8, 16 and 20, 24-h proteinuria of the treated group statis...

journal_title：Renal failure

authors： Ryuzo M,Soares V

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:We undertook this study to evaluate the incidence and outcome of HELLP in Irish patients. In addition, duration and trends of the abnormal laboratory results were studied. STUDY DESIGN:This prospective observational study screened 12068 pregnant women between January 1995 and March 1997. Any pregnant woman w...

journal_title：Renal failure

authors： Abraham KA,Connolly G,Farrell J,Walshe JJ

更新日期：2001-09-01 00:00:00

abstract：:We sought to determine the prevalence, recognition, and consequences of mental impairment among chronic hemodialysis patients. We administered the Mini Mental Status Exam (MMSE), a brief validated method for assessing cognitive mental status that is commonly used by clinicians, to 84 patients from our dialysis units. ...

journal_title：Renal failure

authors： Kutlay S,Nergizoglu G,Duman N,Atli T,Keven K,Ertürk S,Ates K,Karatan O

更新日期：2001-11-01 00:00:00

abstract：:High interdialytic weight gain (IDWG) is considered as an indicator of noncompliance but could also be interpreted as an index of appetite. This study was designed to investigate the relationship IDWG with malnutrition and mortality risk in hemodialysis (HD) patients through a follow-up of 24 months. We divided HD pat...

journal_title：Renal failure

authors： Sezer S,Ozdemir FN,Arat Z,Perim O,Turan M,Haberal M

更新日期：2002-01-01 00:00:00

abstract：:Some experiments on uremia in rats may require an overnight fast in order to empty the gastrointestinal tract, or for other reasons. Previous investigation of normal rats showed that an overnight fast is not completely innocuous and that feeding pure sucrose is a valuable alternative. In the present study, anephric ur...

journal_title：Renal failure

authors： Levine S,Saltzman A

更新日期：2002-03-01 00:00:00

abstract：:Acute tumor lysis syndrome (ATLS), a condition which results from a rapid destruction of tumor cells with massive release of cellular breakdown products, has been well described. However, only a few cases of spontaneous ATLS have been reported in the literature. Acute renal failure (ARF) from spontaneous ATLS has been...

journal_title：Renal failure

authors： Alkhuja S,Ulrich H

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Intravenous iron therapy is now the standard modality of iron supplementation in hemodialysis patients, but its role in predialysis chronic renal failure patients is less well established. The efficacy and safety of intravenous iron dextran as a total dose infusion in predialysis chronic renal failure patien...

journal_title：Renal failure

authors： Anuradha S,Singh NP,Agarwal SK

更新日期：2002-05-01 00:00:00

abstract：:Renal infection, including acute and chronic pyelonephritis, focal bacterial nephritis, renal and perinephric abscess, pyonephrosis and others, represents a spectrum of interrelated conditions. In recent years, computed tomography, ultrasound, nuclear scintigraphy, excretory urography (IVP) and magnetic resonance imag...

journal_title：Renal failure

authors： Yap HJ,Lin CL,Huang CC

更新日期：2002-07-01 00:00:00

abstract：:There is good evidence that by improving dialysis adequacy, morbidity, and mortality of hemodialysis (HD) patients decrease. Dialysis adequacy has also been related to the better control of arterial blood pressure (BP), anemia and improvement of patients' nutritional status. This is a self-control study of 34 HD patie...

journal_title：Renal failure

authors： Panagoutsos SA,Yannatos EV,Passadakis PS,Thodis ED,Galtsidopoulos OG,Vargemezis VA

更新日期：2002-09-01 00:00:00