Abstract:
:Plant viruses of the recently recognized family Amalgaviridae have monopartite double-stranded (ds) RNA genomes and encode two proteins: an RNA-dependent RNA polymerase (RdRp) and a putative capsid protein (CP). Whereas the RdRp of amalgaviruses has been found to be most closely related to the RdRps of dsRNA viruses of the family Partitiviridae, the provenance of their CP remained obscure. Here we show that the CP of amalgaviruses is homologous to the nucleocapsid proteins of negative-strand RNA viruses of the genera Phlebovirus (Bunyaviridae) and Tenuivirus. The chimeric genomes of amalgaviruses are a testament to the effectively limitless gene exchange between viruses that shaped the evolution of the virosphere.
journal_name
Biol Directjournal_title
Biology directauthors
Krupovic M,Dolja VV,Koonin EVdoi
10.1186/s13062-015-0047-8subject
Has Abstractpub_date
2015-03-29 00:00:00pages
12issn
1745-6150pii
10.1186/s13062-015-0047-8journal_volume
10pub_type
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