Abstract:
OBJECTIVE:This study examined the effect of basic fibroblast growth factor (FGF)-2 with an absorbable collagen sponge on angiogenesis and bone regeneration in rat calvarial critical-sized bone defects using microcomputed tomography. METHODS:Forty 7-week-old male Fischer rats were used. The symmetrical critical-sized calvarial bone defects (5 mm diameter) were created. An absorbable collagen sponge with or without FGF-2 (0.1% or 0.3%) was implanted into each bone defect. RESULTS:Blood vessel and bone volumes were significantly higher in the 0.3% FGF-2 group compared with the control and 0.1% FGF-2 groups on day 28. Significantly more osteoblast- and osteoclast-like cells were seen in the 0.3% FGF-2 group. CONCLUSIONS:Thus, FGF-2 increased blood vessel and bone formation in rat calvarial critical-sized bone defects.
journal_name
Implant Dentjournal_title
Implant dentistryauthors
Kigami R,Sato S,Tsuchiya N,Yoshimakai T,Arai Y,Ito Kdoi
10.1097/ID.0b013e31829d19f0subject
Has Abstractpub_date
2013-08-01 00:00:00pages
422-7issue
4eissn
1056-6163issn
1538-2982journal_volume
22pub_type
杂志文章abstract::Factors affecting cell and tissue responses to dental implant biomaterials are typically characterized as spatial and temporal. Spatially, a dental implant must form an interface with both bone tissue for the development and maintenance of biomechanical stability and soft tissue for the prevention of microbial infecti...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/00008505-199807040-00012
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:The aim of this investigation was to assess the efficacy of using subepithelial connective tissue graft (CTG) over the buccal plate in conjunction with 2 different bone graft materials in fresh extraction sites. MATERIALS AND METHODS:Five mongrel dogs were used. Bilateral third (P3) mandibular premolars were e...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0000000000000307
更新日期:2015-12-01 00:00:00
abstract::A case report is presented describing the laboratory fabrication and clinical use of an innovative template. This template was designed to function as a radiographic implant positioning guide, accurate bone sounding guide, and surgical guide. This appliance is intended to serve additional roles as an aid in flap refle...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/00008505-199807020-00005
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:This study evaluated the effect of the platform-switching phenomenon, the use of a smaller diameter abutment on a larger diameter implant platform. Clinical and histological outcomes of the periimplant mucosa around titanium abutments in a nonsubmerged implant were evaluated. MATERIALS AND METHODS:Ten healthy ...
journal_title:Implant dentistry
pub_type: 临床试验,杂志文章
doi:10.1097/ID.0000000000000209
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:To compare the long-term marginal implant bone loss, survival, and radiographic success of single dental implants among current, past smokers, and nonsmokers. PARTICIPANTS AND METHODS:The study was based on a consecutive cohort of patients who received single implants between 2 adjacent natural teeth. Only imp...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0b013e31818c4a24
更新日期:2008-12-01 00:00:00
abstract:PURPOSE:To evaluate the influence of bone marrow aspirate when added to bone block allograft to repair osseous defects. BACKGROUND:Bone-marrow aspirate has been combined with xenograft and allograft particulate material and has produced a significant quantity of new bone growth. However, the use of allograft bone bloc...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0b013e31815c8ef4
更新日期:2007-12-01 00:00:00
abstract::Immediate loading of oral implants has been extensively described in the international literature and the requirements for long-term success are evaluated. The author presents here the critical aspects of the criteria for success as well as describes the characteristics of an implant macro- and microdesign for immedia...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0b013e3181991248
更新日期:2009-06-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to evaluate retrospectively the 3-year outcome of implants placed in augmented maxillary sinuses with minimal residual alveolar bone heights (≤3 mm). MATERIALS AND METHOD:A total of 28 sinus floors were augmented with xenograft, and 58 implants were placed. The outcome measures w...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0000000000000360
更新日期:2016-04-01 00:00:00
abstract:AIMS:The primary aim of this study was to evaluate the 1-year crestal bone loss and success rate of an immediately placed single-stage implant placed and restored by novice operators. A secondary aim was to determine the patient's assessment of the appearance of the final restoration. METHODS:Fifty-one patients receiv...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0b013e3181bcd36b
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVES:The purpose of this article was to introduce a new technique for minimally invasive lateral window sinus augmentation, developed to maximize the amount of residual lateral wall after the procedure. MATERIALS AND METHODS:Fourteen consecutive patients requiring maxillary sinus augmentation by a lateral approa...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0000000000000119
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:This study was performed to investigate the histologic and histomorphometric findings of 2 different types of implant. MATERIALS AND METHODS:Resorbable blasting media (RBM) and sandblasted with larger grit and acid etched (SLA) surfaced implants (24 fixtures in each group) were installed in posterior maxilla o...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0000000000000292
更新日期:2015-10-01 00:00:00
abstract::A calcified alloplast was evaluated as a gap-filling material around implants placed immediately into fresh extraction sockets. Periodontal measurements and computed tomography scans were obtained to evaluate the clinical effectiveness of the alloplast when compared with demineralized freeze-dried bone. To determine w...
journal_title:Implant dentistry
pub_type: 临床试验,杂志文章
doi:10.1097/00008505-200107000-00016
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:To examine periimplant reaction of transplanted soft tissues foreign to oral cavity when compared with local gingiva. METHODS:In 58 oral cancer patients, 210 dental implants were inserted mainly in the mandible after radical surgery and reconstruction. Ninety-six implants penetrated transplants (split skin, mu...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/01.id.0000433935.76603.0a
更新日期:2013-12-01 00:00:00
abstract::The ability to generate 3-dimensional volumetric images of the maxillofacial area has allowed surgeons to evaluate anatomy before surgery and plan for the placement of implants in ideal positions. However, the ability to transfer that information to surgical reality has been the most challenging part of implant dentis...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/01.id.0000202637.61180.2b
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVE:The purpose of this report is to compare satisfaction of patients rehabilitated with full-mouth fixed prostheses using computer-aided flapless implant placement and immediate loading with patients rehabilitated with conventional removable prostheses. MATERIALS AND METHODS:The study included 30 consecutive fu...
journal_title:Implant dentistry
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1097/ID.0000000000000492
更新日期:2017-02-01 00:00:00
abstract::Defects of the oral and maxillofacial region may arise from several reasons such as trauma, infection, cyst, tumor, medication related osteonecrosis of the jaw, and misuse of some irritant agents. For reconstruction, autogenous grafts remain the gold standard among the alternatives. In our case, a 42-year-old woman re...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0000000000000910
更新日期:2019-10-01 00:00:00
abstract:PURPOSE:Bone augmentation is frequently used to create sufficient bone volume for ideal implant placement. Severely resorbed ridges require extensive bone augmentation in the form of block allografts. A 3-dimensional graft technique has been developed to augment atrophic areas. This technique involves modifying the gra...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0b013e31826f7a67
更新日期:2012-12-01 00:00:00
abstract::In the last 30 years, dental implantology has undergone widespread advances in technology and now complex, high-risk procedures are routine. Patients are becoming more vocal in their requests for this service from dentists in private practice and academic institutions. Unfortunately, although treatment modalities have...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/00008505-200101000-00018
更新日期:2001-01-01 00:00:00
abstract::Many of the presently used methods of evaluating osseointegration at second-stage surgery are highly subjective. The Periotest is claimed to offer a more objective means to assess osseointegration by means of microcomputer-controlled percussion. In 1991 the Dental Implant Clinical Research Group initiated a long-term ...
journal_title:Implant dentistry
pub_type: 临床试验,杂志文章
doi:10.1097/00008505-199409000-00003
更新日期:1994-10-01 00:00:00
abstract:OBJECTIVE:To assess the potential of using autologous demineralized tooth matrix (aDTM) in combination with platelet-rich fibrin (PRF) membrane (aDTM/PRF) or PRF membrane alone (control) to preserve the ridge dimension and facilitate bone healing after tooth extraction. MATERIALS AND METHODS:Forty premolar sockets wer...
journal_title:Implant dentistry
pub_type: 杂志文章,随机对照试验
doi:10.1097/ID.0000000000000918
更新日期:2019-10-01 00:00:00
abstract:PURPOSE:This study investigated the bone integration ability of a biphasic calcium phosphate bioceramic implanted in dental alveolus of rats. MATERIALS AND METHODS:A total of 21 male rats were submitted to upper right incisor extraction and implanted with a synthetic bioceramic (Straumann Bone Ceramic). The animals we...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0000000000000172
更新日期:2014-12-01 00:00:00
abstract::Maxillary alveolar atrophy often limits the placement of dental implants. This article reports on a refinement of a technique for widening the atrophic ridge by splitting the alveolar bone longitudinally. Treatment of a patient with a severely resorbed edentulous maxilla is described. Six 4-mm wide by 13-mm long threa...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/01.id.0000156390.58391.64
更新日期:2005-03-01 00:00:00
abstract:INTRODUCTION:The mechanisms by which the loads exerted on implants that support prostheses are modulated during mastication remain unclear. The purpose of this study was to evaluate the effects of food texture on 3-dimensional loads measured at a single implant using a piezoelectric transducer. MATERIALS AND METHODS:T...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0000000000000443
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:To introduce a user-friendly protocol for implant-retained prosthetic rehabilitation of fully edentulous patients based on facial profile and the cephalometric intermaxillary relationship. MATERIALS AND METHODS:The prosthetic rehabilitation of edentulous patients with implants based on facial profile assessmen...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0000000000000856
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:The predictability and success of endosseous dental implants has secured their place as a standard treatment modality. Nevertheless, a small number of implants will fail regardless of operator experience or clinically recognizable cause. This article presents two cases of early failure of two-stage dental im...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/00008505-200207000-00007
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:To document the clinical and histologic outcomes of sinus augmentation using a novel allogenic bone substitute as a sole grafting material. MATERIALS:Patients in need of sinus augmentation before implant placement were recruited for this study. Sinus augmentation procedures were performed following a lateral a...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0b013e3181e59b32
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:To investigate the influence of hierarchical hybrid micro/nano-textured titanium surface features on osteoblast differentiation. MATERIALS AND METHODS:In this study, 3 different implant discs were produced: a hierarchical hybrid micro-/nanostructured titanium surface topography was modified using electrolytic ...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/01.id.0000434273.22605.78
更新日期:2013-12-01 00:00:00
abstract::Passive-fitting mesostructures and superstructures are required to be superimposed on osseointegrated endosseous implants. The tightening of an inaccurate framework to the abutments will transmit stresses to the bone-implant interface. Precision, until now, has been inconsistent and unpredictable with conventional met...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/00008505-200009010-00016
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVES:To investigate whether a different implant geometry with the same potential contact surface area (PCSA) affects the principal stress and strains in bone. MATERIAL AND METHODS:Three-dimensional finite-element models were created with a single endosseous implant embedded in bone. The irregular (IR) dental roo...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0000000000000662
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:The main objective of this study, involving 11 patients, is to share our experience on an integrated treatment modality, namely, the use of cellular therapy simultaneously with surgical reconstruction. Published works show that the implantation of monocytes in ischemic tissue enhances healing by providing neo-a...
journal_title:Implant dentistry
pub_type: 杂志文章
doi:10.1097/ID.0000000000000813
更新日期:2018-10-01 00:00:00