Abstract:
BACKGROUND:As clinical data are increasingly collected and stored electronically, their potential use for comparative effectiveness research (CER) grows. Despite this promise, challenges face those wishing to leverage such data. In this paper we aim to enumerate some of the knowledge management and informatics issues common to such data reuse. DESIGN:After reviewing the current state of knowledge regarding biomedical informatics challenges and best practices related to CER, we then present 2 research projects at our institution. We analyze these and highlight several common themes and challenges related to the conduct of CER studies. Finally, we represent these emergent themes. RESULTS:The informatics challenges commonly encountered by those conducting CER studies include issues related to data information and knowledge management (eg, data reuse, data preparation) as well as those related to people and organizational issues (eg, sociotechnical factors and organizational factors). Examples of these are described in further detail and a formal framework for describing these findings is presented. CONCLUSIONS:Significant challenges face researchers attempting to use often diverse and heterogeneous datasets for CER. These challenges must be understood in order to be dealt with successfully and can often be overcome with the appropriate use of informatics best practices. Many research and policy questions remain to be answered in order to realize the full potential of the increasingly electronic clinical data available for such research.
journal_name
Med Carejournal_title
Medical careauthors
Embi PJ,Hebert C,Gordillo G,Kelleher K,Payne PRdoi
10.1097/MLR.0b013e31829b1de1subject
Has Abstractpub_date
2013-08-01 00:00:00pages
S38-44issue
8 Suppl 3eissn
0025-7079issn
1537-1948pii
00005650-201308001-00008journal_volume
51pub_type
杂志文章相关文献
MEDICAL CARE文献大全abstract:BACKGROUND:While standard methods for conducting economic evaluations have evolved, little attention has been paid to the conduct of these studies in special populations such as children. OBJECTIVES:To build a database of pediatric economic evaluations and to examine trends in publication characteristics over a 20-yea...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/01.MLR.0000088451.56688.65
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:Quality improvement organizations (QIOs) are contracted to improve the quality of care delivered to Medicare beneficiaries. The purpose of this study was to determine whether provider participation in New York State QIO activities resulted in significant improvements in the quality of diabetes care during th...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/01.mlr.0000237420.30406.ea
更新日期:2006-12-01 00:00:00
abstract::The authors provide brief information about the Department of Veterans Affairs (VA) and the Veterans Health Administration, to establish an understanding of this large, multifaceted organization. They then offer an overview of the VA's Office of Research and Development, with particular emphasis on recent and ongoing ...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/01.MLR.0000023950.96307.BD
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:The practice of ordering "Do-Not-Resuscitate" (DNR) varies across hospitals. No research has explored how the DNR variation would affect cross-institutional performance reporting when DNR status is used as a risk adjustor. OBJECTIVE:We sought to assess the impact of DNR variation on performance reporting. ...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/01.mlr.0000167106.09265.4e
更新日期:2005-07-01 00:00:00
abstract::Whereas previous authors have used a variety of strategies to identify use of mental health services, the sensitivity of estimates to the definition of a visit has been little studied. The authors examined the sensitivity of estimates of use of outpatient mental health services in both HMO and fee-for-service plans to...
journal_title:Medical care
pub_type: 杂志文章
doi:
更新日期:1987-09-01 00:00:00
abstract:BACKGROUND:Spinal mobilization and manipulation are 2 therapies found to be generally safe and effective for chronic low back pain (CLBP). However, the question remains whether they are appropriate for all CLBP patients. RESEARCH DESIGN:An expert panel used a well-validated approach, including an evidence synthesis an...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/MLR.0000000000001108
更新日期:2019-05-01 00:00:00
abstract::As part of a comprehensive evaluation of care received by enrollees in a prepaid community health care project, we studied the process of care for enrollees reported to have a urinary tract infection. The care given to 98 patients enrolled in a large prepaid group practice (PGP) and 69 patients seen by 45 physicians i...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/00005650-197806000-00005
更新日期:1978-06-01 00:00:00
abstract:BACKGROUND:Cardiac risk assessment may not be routinely performed. Electronic health records (EHRs) offer the potential to automate risk estimation. We compared EHR-based assessment with manual chart review to determine the accuracy of automated cardiac risk estimation and determination of candidates for antiplatelet o...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/MLR.0b013e31818dce21
更新日期:2009-04-01 00:00:00
abstract::The ability of a medical self-care program to have an impact on the utilization and cost of in-clinic and referral visits in a prepaid group practice was studied by following the medical encounter records of 900 HMO members in 217 families during a 12-month period. A control group selected by randomization after accep...
journal_title:Medical care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005650-198207000-00006
更新日期:1982-07-01 00:00:00
abstract::Data from the Cancer Control Supplement of the 1987 Health Interview Survey (NHIS), a nationally representative sample of the United States population, was used to examine rates of six screening tests for cancer. The rates of screening were compared for people who receive their usual source of medical care in an HMO o...
journal_title:Medical care
pub_type: 杂志文章
doi:
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND:A need exists for adapting existing perioperative risk stratification methods such as the Charlson Comorbidity Index (CCI) for application with hospital administrative data in noncardiac surgery populations. OBJECTIVE:Develop and validate outcome-specific CCIs for predicting inpatient mortality, and cardiac...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/MLR.0000000000000592
更新日期:2016-12-01 00:00:00
abstract::This article summarizes tests of the appropriateness of aggregating specific categories of physical capacities and limitations into aggregate functional status indexes. Self-administered questionnaires were used to gather data from 4,603 people between 14 and 66 years of age. Cumulative indexes defining ranked levels ...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/00005650-198105000-00001
更新日期:1981-05-01 00:00:00
abstract:OBJECTIVE:To compare mental health service utilization and its associated factors between African Americans and whites in the 1980s and 1990s. DESIGN:Household-based longitudinal study with baseline interviews in 1981 and follow-up interviews from 1993 to 1996. SETTING:The Baltimore Epidemiologic Catchment Area (ECA)...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/00005650-199910000-00007
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVES:To investigate the temporal association between symptoms of psychiatric disorder and physical aspects of health-related quality of life (HRQOL) in a sample of HIV-positive adults. METHODS:Sample included 2431 participants at baseline and the first follow-up (FU1; approximately 8 months later). Measures incl...
journal_title:Medical care
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::The increased demand for health status measures in evaluating medical interventions has increased the importance of clarifying when to use generic versus disease-specific health status measures. The authors compared the performance of a well known generic health status measure, the Sickness Impact Profile (SIP), and a...
journal_title:Medical care
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract:BACKGROUND:In Ontario, Canada, the 70/90 regulations were instituted in May 1993 to establish provincial government procurement prices for generic drugs. Accordingly, the first generic entrant's price could not exceed 70% of the incumbent's branded price. Subsequent entrants' prices could not exceed 90% of the first en...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/00005650-200301000-00015
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:In 2007 Cancer Care Ontario (CCO) implemented standardized systematic symptom evaluation in all cancer patients in Ontario using the Edmonton Symptom Assessment System. The initial implementation did not include symptom management guidance and this limited the success of the implementation. Within a short ti...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/MLR.0000000000001084
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Loving-kindness meditation (LKM) is a practice intended to enhance feelings of kindness and compassion for self and others. OBJECTIVES:To assess whether participation in a 12-week course of LKM for veterans with posttraumatic stress disorder (PTSD) is associated with improved positive emotions, decentering,...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/MLR.0000000000000221
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to determine whether parents rate their children's care differently when they also rate their own care than when they do not. METHODS:Subjects were employees of Washington State who had been enrolled in a health plan for at least 6 months and who had at least one covered child. Sub...
journal_title:Medical care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005650-199903001-00007
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:Care for patients with chronic conditions often requires coordination between multiple physicians and delivery sites. Electronic Health Record (EHR) use could improve care quality and efficiency in part by facilitating care coordination. OBJECTIVE:We examined the association between EHR use and clinician pe...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/MLR.0000000000000245
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVES:The present study evaluated alternative patient classification systems for skilled nursing facility and rehabilitation facility patients. METHODS:Medicare patients were selected from a random sample of 27 rehabilitation facilities and 65 skilled nursing facilities participating in a national longitudinal st...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/00005650-199805000-00009
更新日期:1998-05-01 00:00:00
abstract:OBJECTIVE:This paper describes the history of the Department of Veterans Affairs (VA) Community-Based Outpatient Clinics (CBOCs), CBOC Performance Evaluation Project, and characteristics of CBOCs within the VA, and summarizes the findings and implications of the CBOC Performance Evaluation Project. SUBJECTS:There were...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/00005650-200207000-00001
更新日期:2002-07-01 00:00:00
abstract::A new technique for identifying inefficient hospitals, Data Envelopment Analysis (DEA), is field tested by application to a group of teaching hospitals. DEA is found to provide meaningful insights into the location and nature of hospital inefficiencies as judged by the opinion of a panel of hospital experts. DEA provi...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/00005650-198410000-00005
更新日期:1984-10-01 00:00:00
abstract:BACKGROUND:Emergency Department (ED) boarding threatens patient safety. It is unclear whether boarding differentially affects patients admitted to intensive care units (ICUs) versus non-ICU settings. RESEARCH DESIGN AND SUBJECTS:We performed a 2-hospital, 18-month, cross-sectional, observational, descriptive study of ...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/MLR.0000000000000902
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Minority breast cancer patients tend to have higher rates of adjuvant treatment underuse. We implemented a web-based intervention that closes referral loops between surgeons and oncologists at inner-city safety-net hospitals serving high volumes of minority breast cancer patients to assist these hospitals an...
journal_title:Medical care
pub_type: 杂志文章,多中心研究
doi:10.1097/MLR.0000000000000458
更新日期:2016-02-01 00:00:00
abstract::In a large randomized trial involving over 2,000 women with abnormal cervical cytology (pap smear), three clinic-based interventions were tested as strategies to increase return rates for screening follow-up: 1) a personalized follow-up letter and pamphlet; 2) a slide-tape program on pap smears; and 3) transportation ...
journal_title:Medical care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005650-199203000-00004
更新日期:1992-03-01 00:00:00
abstract::A factorial design randomized controlled trial to test several clinically feasible strategies primary-care practitioners may use in routine practice to increase patient participation in occult blood testing for colorectal cancer is reported. Three compliance-enhancing intervention strategies (physician/nurse talk, and...
journal_title:Medical care
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00005650-198610000-00004
更新日期:1986-10-01 00:00:00
abstract::This study, like two earlier studies by the author, examines the effects of changing medical technologies on medical care costs by comparing the costs of treatment of a number of common illnesses at two points in time, 1971 and 1981. While the earlier studies, covering the periods 1951-1964 and 1964-1971, showed that ...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/00005650-198512000-00004
更新日期:1985-12-01 00:00:00
abstract:OBJECTIVE:A number of health care initiatives seek to improve health outcomes by increasing access to outpatient services while reducing preventable acute events. We evaluated disparities between American Indian and Alaska Native (AI/AN) and non-Hispanic white (white) Medicare enrollees in access to outpatient preventi...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/MLR.0000000000000698
更新日期:2017-06-01 00:00:00
abstract::Physicians who participate in preferred provider organizations (PPOs) usually agree to various types of utilization review and sometimes discount their charges or agree to accept lower fees. This study was performed to determine whether they provided more or fewer services to their PPO patients than to their indemnity...
journal_title:Medical care
pub_type: 杂志文章
doi:10.1097/00005650-199010000-00004
更新日期:1990-10-01 00:00:00