当前位置： SCI文献检索 > RESUSCITATION期刊下所有文献 > Comparison of non-calibrated pulse-contour analysis with continuous thermodilution for cardiac output assessment in patients with induced hypothermia after cardiac arrest.

Comparison of non-calibrated pulse-contour analysis with continuous thermodilution for cardiac output assessment in patients with induced hypothermia after cardiac arrest.

Abstract：

AIM:Induced mild hypothermia after cardiac arrest interferes with clinical assessment of the cardiovascular status of patients. In this situation, non-invasive cardiac output measurement could be useful. Unfortunately, arterial pulse contour is altered by temperature, and the performance of devices using arterial blood pressure contour analysis to derive cardiac output may be insufficient. METHODS:Mild hypothermia (32-34°C) was induced in eight patients after out-of-hospital cardiac arrest and successful resuscitation. Cardiac output (CO) was measured simultaneously by continuous thermodilution using a pulmonary artery catheter and a cardiac output monitor (Vigilance II, Edwards Lifesciences) and by pulse contour analysis using an arterial line and the Vigileo monitor (Edwards Lifesciences) during both normothermia (>36°C) and hypothermia. Continuous CO from both monitors was compared (Bland-Altman) and concordance of changes measured in consecutive 8-min intervals was measured. RESULTS:Mean cardiac output was 3.9±1.2 l/min during hypothermia and 6.1±2.6 l/min during normothermia (p<0.001). During hypothermia (normothermia), bias was 0.23 (0.77)l/min, precision (1 SD) was 0.6 (0.72) l/min, and the limits of agreement were -1.06 to 1.51 (-0.64 to 2.18) l/min, corresponding to a percentage error of ±34% (±24%). Concordance of directional CO changes >10% was 53.9% in hypothermia and 51.4% in normothermia. CONCLUSION:Induced hypothermia was not associated with increased bias or limits of agreement for the comparison of Vigileo and continuous thermodilution, but percentage error was high during normothermia and increased further during hypothermia. Less than 50% of clinically relevant CO changes during hypothermia were concordant.

journal_name

Resuscitation

journal_title

Resuscitation

authors

Haenggi M,Barthelmes D,Ulmer H,Takala J,Jakob SM

doi

10.1016/j.resuscitation.2010.12.015

subject

Has Abstract

pub_date

2011-04-01 00:00:00

pages

423-6

issue

eissn

0300-9572

issn

1873-1570

pii

S0300-9572(11)00006-2

journal_volume

pub_type

杂志文章

在线工具

Comparison of non-calibrated pulse-contour analysis with continuous thermodilution for cardiac output assessment in patients with induced hypothermia after cardiac arrest.