Abstract:
BACKGROUND:Perinatal anoxia rarely causes myoclonus as the main neurologic abnormality. The exact neuronal mechanism underlying myoclonus induced by perinatal anoxia remains unknown. Some studies have indicated that the development of involuntary movements may be related to the maturation of the thalamus after birth. OBJECTIVES AND METHODS:Here, we describe the first case of a patient who developed action myoclonus after experiencing perinatal anoxia and was successfully treated by chronic deep brain stimulation (DBS) of the thalamus (thalamic DBS). RESULTS AND CONCLUSION:The effectiveness of chronic thalamic DBS in this patient supports the concept of involvement of the thalamus in post-perinatal anoxic myoclonus.
journal_name
Stereotact Funct Neurosurgjournal_title
Stereotactic and functional neurosurgeryauthors
Kobayashi K,Katayama Y,Otaka T,Obuchi T,Kano T,Nagaoka T,Kasai M,Oshima H,Fukaya C,Yamamoto Tdoi
10.1159/000315464subject
Has Abstractpub_date
2010-01-01 00:00:00pages
259-63issue
4eissn
1011-6125issn
1423-0372pii
000315464journal_volume
88pub_type
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journal_title:Stereotactic and functional neurosurgery
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