Abstract：
:We report a boy with acute lymphoblastic leukaemia (ALL) treated with chemotherapy and prophylactic cranial irradiation to a dose of 24 Gy. Six years after diagnosis he developed a glioma and died. Prior to 1979, four cases of second malignant neoplasm (SMN) of the brain had been reported in children treated for ALL. These SMNs occurred within 2 years of the original diagnosis (median 1.3 years) and at least two of four patients had not received prior radiotherapy. Since 1979, 28 cases of SMN of the brain have been reported including nine of 468 (1.9%) long-term survivors in one study. All occurred more than 3.7 years from diagnosis (median 6.5 years; range 4-13 years) and all received cranial irradiation (median 24 Gy; range 20-48 Gy). These data indicate a change in the pattern of SMNs which is most likely due to the introduction of cranial irradiation. As well, the frequency of SMNs in children treated for ALL appears to have increased, although it is still no greater than the risk of SMNs developing following the treatment of any other primary childhood neoplasm.
journal_name
J Paediatr Child Healthjournal_title
Journal of paediatrics and child healthauthors
Vowels MR,Tobias V,Mameghan Hdoi
10.1111/j.1440-1754.1991.tb00344.xsubject
Has Abstractpub_date
1991-02-01 00:00:00pages
43-6issue
1eissn
1034-4810issn
1440-1754journal_volume
27pub_type
杂志文章,评审abstract：:Two hundred and seven Australian paediatricians were sent a questionnaire to determine whether they undertook developmental screening and/or assessment. Replies were received from 140 (68%) paediatricians of whom 115 (82%) stated they did developmental screening and 58 (41%) said they did developmental assessment. The...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1993.tb00534.x
更新日期：1993-10-01 00:00:00
abstract：AIM:Currently, there are no population-based or hospital-based studies on the full spectrum of paediatric head injuries (HIs) in Australia. We set out to provide detailed information on the incidence rates, causes and clinical management of all severities of HI in children and adolescents at an Australian tertiary refe...
journal_title：Journal of paediatrics and child health
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journal_title：Journal of paediatrics and child health
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abstract：:A male neonate with partial monosomy 10q and partial trisomy 11q, due to paternal balanced translocation, and who had cerebellar and olfactory lobe hypoplasia, cardiovascular defects, duodenal atresia and imperforate anus, is presented. To the best of our knowledge, this is the first report on this combination of chro...
journal_title：Journal of paediatrics and child health
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doi：10.1046/j.1440-1754.2001.00587.x
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abstract：:Congenital chylothorax is the accumulation of lymphatic fluid within the pleural space. Cases unresponsive to conservative management usually require surgery. Octreotide has been used successfully to treat post-traumatic chylothoraces in the paediatric and adult population. Its exact mode of action is uncertain but it...
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.15289
更新日期：2020-12-09 00:00:00
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更新日期：2012-03-01 00:00:00
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pub_type： 杂志文章
doi：10.1111/j.1440-1754.2004.00461.x
更新日期：2004-09-01 00:00:00
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pub_type： 杂志文章
doi：10.1111/j.1440-1754.2008.01373.x
更新日期：2008-11-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12708
更新日期：2014-10-01 00:00:00
abstract：AIM:This study examined the prevalence and risk factors of fine motor delay in Australian pre-school children from low-income communities. METHODS:Children from the Early Start Baseline Study completed the Ages and Stages Questionnaire (3rd edn.). Age, sex, executive function and family characteristics were assessed a...
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doi：10.1111/jpc.15152
更新日期：2021-01-01 00:00:00
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doi：10.1111/jpc.12794
更新日期：2015-07-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,评审
doi：10.1111/jpc.12497
更新日期：2014-07-01 00:00:00
abstract：AIM:Investigate the incidence, etiological pattern and the antimicrobial resistance of late-onset neonatal infections over a period of 5 years. METHODS:Longitudinal audit of neonatal sepsis from January 2005 to December 2009, in the main maternity hospital in Kuwait. Late-onset neonatal infection was defined as the cu...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2012.02432.x
更新日期：2012-07-01 00:00:00
abstract：OBJECTIVE:To discuss treatment modalities for subglottic haemangioma (SGH). METHODOLOGY:Case report of two children definitively managed by different modalities. RESULTS:Management by CO2 laser vaporization in one child, and laser followed by interferon 2-alpha in the second child were both successful in controlling ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：
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abstract：AIM:To describe the prevalence and risk factors of recurrent otitis media (rOM) in an urban Australian population at 3 years of age. METHODS:Cross-sectional examination of prevalence and risk factors of rOM in 2280 participants from the Raine Study enrolled from public and private hospitals in Perth, Western Australia...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12741
更新日期：2015-04-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2005.00583.x
更新日期：2005-04-01 00:00:00
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journal_title：Journal of paediatrics and child health
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doi：10.1111/jpc.12516
更新日期：2014-07-01 00:00:00
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doi：10.1111/j.1440-1754.2008.01429.x
更新日期：2009-01-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2020-04-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2011.02178.x
更新日期：2011-09-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.13024
更新日期：2016-04-01 00:00:00
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journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,随机对照试验
doi：10.1111/jpc.12277
更新日期：2013-07-01 00:00:00
abstract：:A baby with ambiguous genitalia and 46XY chromosomes was raised as a female. Sudden and unexpected death at 11 months of age led to a post-mortem diagnosis of Drash syndrome. ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1990.tb02436.x
更新日期：1990-08-01 00:00:00
abstract：OBJECTIVE:To identify which clinical situations are the most difficult to manage for general paediatricians in Victoria, Australia. METHODS:Self-administered questionnaires were sent to general paediatricians in Victoria. They were asked their opinions regarding what were the most difficult and the most dangerous clin...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2002.00017.x
更新日期：2002-10-01 00:00:00
abstract：:Circumcision has been the traditional treatment for phimosis, but now is not the only management option, the best of which appears to be topical steroid application. Importantly, the literature suggests that phimosis probably is over-diagnosed, indicating that a prospective, randomized controlled study is needed to co...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,评审
doi：10.1111/j.1440-1754.1996.tb02554.x
更新日期：1996-08-01 00:00:00
abstract：:The birthweight and gestational age specific mortality of singleton Aboriginal and White infants born in Western Australia during the period 1980-86 is described. The analyses are based on the approximately 8000 Aboriginal and 143,000 White births notified through the Western Australia Midwives' system, which were lin...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1993.tb00439.x
更新日期：1993-02-01 00:00:00
abstract：OBJECTIVE:To determine the common features of small bowel injury (SBI) in childhood and the consequences of delayed diagnosis. METHODOLOGY:A retrospective case review was performed of children with traumatic SBI between January 1988 and November 1999. RESULTS:Twenty-eight patients were identified with SBI. Road traum...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2000.00502.x
更新日期：2000-06-01 00:00:00
