Abstract:
:Lung cancer is globally the second most common form of cancer in both men and women and the single largest cause of cancer-related mortality in the world. It is a disease with poor prognosis and the survival statistics have scarcely improved since historical times. The advent of targeted therapies has caused an incremental increase in survival figures. Nevertheless, significant progress in treatment outcomes need to be achieved before any perceptible improvement in overall survival of lung cancer patients becomes evident. The use of active-specific immunotherapy or cancer vaccines for the treatment of lung cancer is still in its infancy. Nevertheless several cancer vaccines have demonstrated clinical effects and improvements in overall survival in phase II and phase III trials and several more clinical trials are currently ongoing. This review summarizes the recent developments in NSCLC vaccines.
journal_name
Minerva Chirjournal_title
Minerva chirurgicaauthors
Palma M,Choudhury A,Mellstedt Hsubject
Has Abstractpub_date
2009-12-01 00:00:00pages
643-53issue
6eissn
0026-4733issn
1827-1626pii
R06095173journal_volume
64pub_type
杂志文章,评审abstract::Carotid-jugular arteriovenous fistulas (AVF) are extremely rare with only 20 cases reported in the literature up to December 1996. The case of a 74-year-old man (the oldest reported in the literature) with abnormal communications between the external carotid artery and the internal jugular vein is reported. The condit...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract::The authors evaluate the incidence of varicocele after having examined 18,800 healthy white men members of the Italian Army Corps born in 1966 and visited in 1985. They found a varicocele in 775 patients (4.12%), in 5 was present bilaterally, and in 770 in the left side. In 45 patients the surgical treatment was alrea...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1990-03-31 00:00:00
abstract::The aneurysm of the popliteal artery is the most commonly treated non-aortoiliac aneurysm, accounting for more than 70% of all peripheral aneurysms. The rupture of a popliteal aneurysm is rare and it is often misdiagnosed. In the case of a 46-year old female patient here reported, the patient was referred to our depar...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2012-08-01 00:00:00
abstract::Twenty-two patients undergoing major head and neck surgery were included in a randomized trial to value the efficacy and side effects of parenteral short-term antibiotic prophylaxis of post-operative infections. Two different antibiotic regimens were compared: group A, ceftazidime i.v. (2 g) in three doses (half an ho...
journal_title:Minerva chirurgica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1989-11-30 00:00:00
abstract::Pancreatic pseudocysts are a rare pathology in pancreas diseases. Their incidence has been increasing in recent years and the man-woman ratio is equal. The aetiopathogenetic mechanism is attributable to dilation of the pancreatic ducts with later formation of a cyst due to blocked flow. Symptomatology is bound up prev...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1989-04-30 00:00:00
abstract::The authors report a case of gastric leiomyoblastoma, a rare benign neoplasm that can sometimes undergo a malignant course. The main clinical an pathological issues are reviewed, in order to offer guidance as to the best suited surgical approach. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1992-11-01 00:00:00
abstract:BACKGROUND:Surgeon's position during open cholecystectomy operation has been standardized since more than 100 years, being traditionally fixed at the right side of the patient. Only a few French authors adopted the "left location" just for the time requested for the common bile duct exploration. METHODS:In this paper ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00
abstract:INTRODUCTION AND METHODS:After reviewing the literature on the subject, the authors analysed the patients suffering from intestinal infarction selected from those examined between 1-1-1985 and 31-12-1995. It was found that out of 11,500 patients only 9 (0.07%) suffered from this pathology. RESULTS:The authors found th...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract::The authors report a case of severe revascularization syndrome which occurred following traumatic vascular lesion to a lower limb. They focus attention on the mechanisms which make this syndrome more frequent and more severe in traumatic lesions as opposed to that observed following acute arterial obstruction secondar...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract::Non-hypertrophic breast ptosis are common diseases. Various degree of ptosis and different involutions of the breast tissue can condition the surgical treatment. Plastic surgery must provide the best surgical treatment in any case. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1994-11-01 00:00:00
abstract::A retrospective series of 30 (2.8%) cases of cholelithiasis out of 1064 abdominal aortic aneurysmectomies is presented. 21 subjects underwent aneurysmectomy and prosthetic grafting combined with cholecystectomy. Complications related to the combined operation, early or late (6 months to 8 years follow-up was available...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract::Echotomography was used in the diagnosis of abdominal disease in children. The results obtained were compared with those given by conventional methods. The soundness of echotomography in the location and indication of the size and structure of lesions was demonstrated in a series of 20 cases. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1978-05-15 00:00:00
abstract::In the present study the A. try to assess the usefulness of ultrasound in detecting blending risk in portal hypertension. Endoscopic and sonographic findings of 35 cirrhotic patients with esophageal varices were compared to a control group of 27 hepatopathy patients without portal hypertension, observed in the same de...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Spontaneous rupture is a life-threatening complication of HCC, occurring in 4.8-26% of cases. Liver failure is the main cause of death. Debates still remain on the most appropriate treatment in such patients because of the high operative mortality of emergency surgery and the high risk of rebleeding and less...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2002-06-01 00:00:00
abstract::The aim of this work is to assess the list of fine needle aspiration in the diagnosis of lesions of the parotid. Thirty-nine patients suffering from parotid pathology were subjected to cytology examination through fine needle aspiration. Thirty seven patients subjected to surgical operation have a histological compari...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1993-10-31 00:00:00
abstract::Anaplastic carcinoma of the thyroid is a highly aggressive neoplasm with quickly total course. It is characterized by an average survival of 4-12 months. It infiltrates precociously into the windpipe, oesophagus, vessels of the neck and gives distant metastases in 10-48% of cases. In 30.8 to 80% of cases, this carcino...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1993-11-01 00:00:00
abstract::Typical sites of bronchogenic carcinoma metastases are liver, brain, bones or adrenal glands. Rarely and in advanced dissemination phase it could involve the skeletal muscle. Two cases of metastases in the skeletal muscle from bronchogenic carcinoma, one of which revealed this neoplasia, are reported. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1999-06-01 00:00:00
abstract::Boerhaave's syndrome or postemetic rupture of the esophagus, carries a high morbidity and mortality. The authors report a delayed Boerhaave's syndrome diagnosis (3 days), successfully treated by right thoracoscopic debridement in prone position. Thanks to gravity the cardiopulmonary bloc drops back and the access to t...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:The aim of this article is to describe the technique used in the treatment of ventral hernia using the laparoscopic method and at the same time to evaluate the possible advantages of this surgical approach. METHODS:The clinical case we present regards a case of a patient who had undergone a double eventratio...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2001-12-01 00:00:00
abstract::A case of distal volvulus of the stomach as a cause of acute intestinal obstruction in a paraesophageal hernia is presented. The patient, an old woman aged 82, had been suffering from abdominal pain and vomiting for about 48 hours. She successfully underwent emergency operation for the reduction of hernia and plasty o...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1989-10-31 00:00:00
abstract::A case of a young male operated on for acute appendicitis due to a carcinoid of the base is reported. Since the tumor was infiltrating the resection margin of the appendix, the patient was later treated with a right hemicolectomy. Carcinoid tumor is unusual, but can be encountered several times during the career of a ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::The authors report a case of urachal fistula diagnosed after repeated omphalitis, this disease was associated with coronal hypospadias. Diagnosis was done thanks to a fistulography; subsequently, during the operation, to evidence the fistula, this was injected with methylene blue, this expedient showed that the fistul...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1997-10-01 00:00:00
abstract::The Authors analyse 121 cases of patients affected by abdominal malignant tumors, who underwent a palliative operation. Although the number of the examinated cases is small, it appears clear that the longest survival requires, when possible, the removal of most of the malignant tissue. This seems to be in accordance w...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1979-02-15 00:00:00
abstract:BACKGROUND:Meconium ileus (MI) is a form of neonatal intestinal obstruction due to an abnormal thickened meconium within the terminal ileum. The aim of this retrospective paper is to review our experience with neonates affected from MI treated at our institute over a twenty year period. METHODS:This report deals with ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
abstract::Among the other complications of enterostomy, prolapse deserves particular mention on account of the therapeutic problems involved in its correction. Based on a report of the authors' personal experience, the paper focuses on the mechanisms of onset and, above all, on the most appropriate forms of treatment, before co...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1990-05-15 00:00:00
abstract::The key concepts regarding nutrition of elderly patients prior to surgery are outlined. The main metabolic changes that occur during surgical stress, paying special attention to the characteristics of elderly patients, are described. Lastly, the caloric-energy intake required by postoperative geriatric patients is eva...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1999-01-01 00:00:00
abstract::The paper describes a case of traumatic hernia of the diaphragm, complicated by mixed gastric volvulus, with a rapid onset and severe clinical symptoms. The etiopathogenesis, diagnosis and therapeutic methods inherent in this rare affliction are discussed. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1989-11-15 00:00:00
abstract:BACKGROUND:Gastroduodenal obstruction is a preterminal event in patients with advanced and recurrent malignancies of the stomach, pancreas, and duodenum. It severely limits the quality of life in affected patients due to constant vomiting and associated malnutrition. Gastroduodenal stent placement is a very safe and ef...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:10.23736/S0026-4733.16.06457-9
更新日期:2017-06-01 00:00:00
abstract::The authors report their experience on 313 liver transplantations performed in 255 patients. In 51.7% the indication to liver transplant was the cirrhosis, post alcoholic in 39.5% and post-hepatitis in 24.1%. The global mortality was 34.9% (89/255) with an actuarial survival of 53% at 74 months. We registered 10 cases...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1993-09-30 00:00:00
abstract::Mechanistic reasoning suggests that since antireflux surgery treats the gastroesophageal reflux that is the major known risk factor for Barrett's esophagus, it should have a beneficial effect on the biology of Barrett's disease. Due to a lack of adequate data, whether this is the case remains uncertain. Most studies, ...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:2011-02-01 00:00:00