Abstract：
:The lifetime risks for both breast and ovarian cancer for BRCA mutation carriers far exceeds the general population risk of 13% for breast cancer and 1.4% for ovarian cancer. BRCA carriers have unique and medically complicated decisions to make regarding their cancer treatment or risk reduction. As BRCA testing becomes increasingly common among unaffected individuals in families with a previously documented BRCA mutation, there are a growing number of individuals with unique psychosocial needs and concerns. This review paper describes the BRCA 1/2 population, discusses preimplantation genetic diagnosis (PGD), and describes the decisions and ethical issues related to PGD among the BRCA 1/ 2 population.
journal_name
Minerva Medjournal_title
Minerva medicaauthors
Quinn GP,Vadaparampil ST,Bower B,Friedman S,Keefe DLsubject
Has Abstractpub_date
2009-10-01 00:00:00pages
371-83issue
5eissn
0026-4806issn
1827-1669pii
R10092984journal_volume
100pub_type
杂志文章,评审相关文献
MINERVA MEDICA文献大全abstract：:PRA (in the supine and erect subject) and urinary sodium before and after acute treatment (100 mg i.m.) and chronic treatment (100 mg per os for 8 days) were examined in two groups of subjects with no signs of cardiovascular or renal disease. It was found that indomethacin, which is a well-known inhibitor of prostagla...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1978-09-15 00:00:00
abstract：:The present paper deals with an ischaemic syndrome which may affect an area of lower limb vessels with latent arteriopathy if limbs or whole body are immersed in very warm water. Two cases are described in which ischaemia appeared when the limbs involved were immersed in warm water (38 degrees C). Ischaemia may be exp...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1984-10-27 00:00:00
abstract：:Following the observation of a high percentage of bacterial resistance to antibiotics, the mechanisms of the establishment and transmission of such resistances on an extra-chromosomal basis (R factors) are examined in detail. After noting that the increased incidence and spread of bacterial strains resistant to chemot...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1975-04-28 00:00:00
abstract：:Data from 1848 cases of attempted suicide on the files of the Milan University Emergency Psychiatry Ward and 990 suicides recorded by the Milan Legal Medicine Department in the period 1964-1969 were computerised on specially prepared cards, designed to permit objective study of acts of self-destruction in the light of...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1977-09-08 00:00:00
abstract：METHODS:The peripheral blood lymphocytes and lung function have been studied in 25 patients: 12 affected by atopic asthma and 13 affected by non atopic asthma. RESULTS:The results obtained indicate that peripheral blood CD3 and CD4 cell as well as HLA-DR marker are higher in the extrinsic asthma group. CONCLUSIONS:Th...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:Urine and stool total nitrogen was measured using the Carlo Erba Strumentazione NA 1500 nitrogen analyzer. Determinations were carried out on 10 mcl, 20 mcl and 50 mcl urine samples and on 20-50 mg stool samples. Both urine and stool data distributions were normal, thus indicating the reliability of the method. The NA...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1986-04-28 00:00:00
abstract：:The thyroid activity of twenty euthyroid patients, with single or multiple "cold" nodules was investigated, with determination of seric T3, T4, reverse-T3 (rT3) and TSH. The blood-drags were performed respectively, during (with seric samples from the inferior thyroid vein ipsilateral to the affected lobe) and after (1...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1986-05-19 00:00:00
abstract：BACKGROUND:Up to 50% of patients suffering from acute decompensated heart failure show normal or slightly reduced left ventricular ejection fraction (LVEF). This syndrome, which is known as "heart failure with preserved ejection fraction" (HFpEF) is associated with increasing age. Epidemiological studies could portrait...
journal_title：Minerva medica
pub_type： 杂志文章
doi：10.23736/S0026-4806.20.06447-2
更新日期：2020-03-12 00:00:00
abstract：:The most frequent causes of the feeling of "being a burden" in elderly people dependent on others due to chronic disabling pathologies are described. Often this feeling is the main, and sometimes the only reason for their isolation from the community. Suggestions are made for the removal of this feeling, which is felt...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1983-05-19 00:00:00
abstract：:Serum levels of carcinoembryonic antigen (CEA) and tissue polypeptide antigen (TPA) were investigated in 53 lung cancer patients. The higher percentage of patients with serum CEA positivity was observed within the anaplastic lung cancer group. TPA serum positivity was found in similar percentage in all the examined gr...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1986-03-17 00:00:00
abstract：:The IATA regulations on the scheduled flight transportation of sick passengers is presented and the problems involved illustrated. Among other recommendations it is suggested that collaboration with the patients' doctors in filling up the MEDIF form is essential for the sick passenger's comfort and safety. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1983-08-25 00:00:00
abstract：:A case of dyslipoproteinaemia of type V in a woman suffering from primary hypothyroidism, florid diabetes mellitus and obesity is reported. The case is commented on in general and as regards possible correlations between the diseases and the dyslipoproteinaemic picture. The various therapeutic treatment employed and r...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1976-07-21 00:00:00
abstract：:15 male heroin addicts, 19-26 yr, were given 20 hospital treatments for detoxifying. Therapeutic program was based on GABAergic drugs (1-glutamine, sodium valproate, pyridoxine), low doses psychodrugs and acupuncture, added from the 3rd day. A full avoidance of the withdrawal syndrome was reached in 15 out of 18 Ss so...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1982-03-31 00:00:00
abstract：:Radiation treatment using low power laser beams is recommended for chronic or recurring lesions. Personal experience is reported with emphasis on the fact that He-Ne laser treatment should be employed when topical or surgical therapy fails. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1984-02-11 00:00:00
abstract：:Mucositis is the result of the cytotoxic effects of many treatments given for hematological malignancies (HMs); it represents a major source of potentially devastating clinical complications and portrays negative consequences on the patient's management, such as a longer hospitalization, the need of analgesic and tota...
journal_title：Minerva medica
pub_type： 杂志文章,评审
doi：
更新日期：2011-02-01 00:00:00
abstract：:A marker of neuroendocrine differentiation, neuron-specific enolase (NSE) is assessed in the diagnosis of small cell lung cancer (SCLC). The market was found to be highly sensitive and extremely specific in high risk groups (smokers and chronic bronchitics). ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1987-04-15 00:00:00
abstract：:Measurement of influenza A/Torino/1/75, A/MRC 11 and A/Scotland/840/74 viruses h.i. antibodies in a sample of the Turin population represented by 200 non-vaccinated adults, showed that the percentage of subjects carrying antibiodies at the minimum titre of 1/10 was respectively 83, 78,5 and 52 and respective mean titr...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1977-02-11 00:00:00
abstract：: ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：10.23736/S0026-4806.19.06102-0
更新日期：2019-05-06 00:00:00
abstract：:Determination of serum bile acids has long been regarded as the most sensitive indicator of liver function. An assessment was made of the clinical applicability of RIA evaluation of two of these acids, cholylglycine (CG) and sulpholithochocholyglycine (SLGG), on an empty stomach and 2hr after a cholecystokinetic meal ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1984-01-28 00:00:00
abstract：:Colorimetry was used to assay blood copper levels in 13 asbestosis patients (mean age 55.5) selected by excluding all cases with an evident clinical anamnesis of dietary imbalances or other significant pathologies. The results show increased blood copper in 11 out of 13 patients, the mean level in this group being sig...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1988-10-01 00:00:00
abstract：:308 mammary needle aspirations for suspected clinical forms of mammary cystitis were performed between 1971 and 1980 at the Savona Oncological Centre. The evacuated cystic cavity was always treated with a concentrated Lugol solution, the sclerosing and modifying properties of which foster wall adherence and prevent re...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1982-11-17 00:00:00
abstract：:Sixty cases of mammary secretion were studied using cytological examinations of the mammary secretion, traditional mammography, galactography and histological examination of bioptic samples. Comparison of the results produced by the different techniques highlighted the importance of galactography for the description o...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：:In this present research work the Authors think that a preliminary echocardiography study may be useful to evoluate the type of answer of the cardiac muscle to the artificial stimulus; they deem, forthmore, thot, among the ecocardiografic obtainable parameters the principle importance must be attributed to the velocit...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1980-08-25 00:00:00
abstract：:Progressive systemic sclerosis (PSS), a disease still of unknown origin, is a generalized autoimmune disorder characterized by immunological abnormalities, microvascular dysfunction, and tissue fibrosis. The mechanism leading to selective microvascular injury in PSS is not completely known, however it is now clear tha...
journal_title：Minerva medica
pub_type： 杂志文章,评审
doi：
更新日期：1998-05-01 00:00:00
abstract：AIM:Adequate postoperative analgesia is a prerequisite for successful ambulatory surgery and continues to be a challenge for anesthesiologists. The goal of the study was to analyze what are determinants of patients' overall satisfaction in postoperative pain management after ambulatory hand surgery. METHODS:Patients u...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：2011-06-01 00:00:00
abstract：:A number of pathogenetic moments have been identified in primary or essential hypertension in recent years. Marked variations have been noted in plasma volume, cardiac output, neurosympathetic tone, the renin-angiotensin system, and the aldosterone-adrenal neurosympathetic regulation system. Biological and clinical st...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1975-02-21 00:00:00
abstract：:The literature reports many cases of eosinophilic pulmonary infiltrations, with different etiology. In our case clinical pictures were not very clear and specific at first and the clinical course was altered by an ex adjuvantibus steroid treatment before admission to hospital. It was new and unusual because it present...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：:The aim of this study is to evaluate the effectiveness of fluoxetin associated with cyclobenzaprine vs cyclobenzaprine in the treatment of fibromyalgia. Twenty-one females with fibromyalgia were randomly assigned to 2 groups: group A (11 patients) was treated over 12 weeks with fluoxetin (20 mg/die) and cyclobenzaprin...
journal_title：Minerva medica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1994-03-01 00:00:00
abstract：:Data reported in the literature on the existence of a circadian rhythm in PTH secretion are contradictory. In order to assess whether haematic PTH levels vary over a 24 hour period, the plasma levels of the hormone were evaluated at 6 different times during the day (12, 19, 24, 2, 4, 6 hours) in a group of 10 healthy ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1985-06-30 00:00:00
abstract：:The case of a sixteen year old girl with hereditary spherocytosis, submitted to splenectomy, is presented. After operation the patient had four serious infections; for this reason she is now treated by antibiotic prophylaxis. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1990-09-01 00:00:00
