Abstract:
OBJECTIVE:The aim of this study was to use morphological as well as biochemical (T2 and T2* relaxation times and diffusion-weighted imaging (DWI)) magnetic resonance imaging (MRI) for the evaluation of healthy cartilage and cartilage repair tissue after matrix-associated autologous chondrocyte transplantation (MACT) of the ankle joint. MATERIALS AND METHODS:Ten healthy volunteers (mean age, 32.4 years) and 12 patients who underwent MACT of the ankle joint (mean age, 32.8 years) were included. In order to evaluate possible maturation effects, patients were separated into short-term (6-13 months) and long-term (20-54 months) follow-up cohorts. MRI was performed on a 3.0-T magnetic resonance (MR) scanner using a new dedicated eight-channel foot-and-ankle coil. Using high-resolution morphological MRI, the magnetic resonance observation of cartilage repair tissue (MOCART) score was assessed. For biochemical MRI, T2 mapping, T2* mapping, and DWI were obtained. Region-of-interest analysis was performed within native cartilage of the volunteers and control cartilage as well as cartilage repair tissue in the patients subsequent to MACT. RESULTS:The overall MOCART score in patients after MACT was 73.8. T2 relaxation times (approximately 50 ms), T2* relaxation times (approximately 16 ms), and the diffusion constant for DWI (approximately 1.3) were comparable for the healthy volunteers and the control cartilage in the patients after MACT. The cartilage repair tissue showed no significant difference in T2 and T2* relaxation times (p > or = 0.05) compared to the control cartilage; however, a significantly higher diffusivity (approximately 1.5; p < 0.05) was noted in the cartilage repair tissue. CONCLUSION:The obtained results suggest that besides morphological MRI and biochemical MR techniques, such as T2 and T2* mapping, DWI may also deliver additional information about the ultrastructure of cartilage and cartilage repair tissue in the ankle joint using high-field MRI, a dedicated multichannel coil, and sophisticated sequences.
journal_name
Skeletal Radioljournal_title
Skeletal radiologyauthors
Quirbach S,Trattnig S,Marlovits S,Zimmermann V,Domayer S,Dorotka R,Mamisch TC,Bohndorf K,Welsch GHdoi
10.1007/s00256-009-0682-1subject
Has Abstractpub_date
2009-08-01 00:00:00pages
751-60issue
8eissn
0364-2348issn
1432-2161journal_volume
38pub_type
杂志文章abstract::We report a case of liposarcoma in a 17-year-old boy in which both the radiographs and histology demonstrated multiple punctate calcifications. In addition, this unusual variant consisting of myxoid, round cell and well-differentiated liposarcoma behaved aggressively resulting in the death of the patient. ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-002-0561-5
更新日期:2002-11-01 00:00:00
abstract::Peer-reviewed abstracts presented at the 2008 Society of Skeletal Radiology (SSR) Annual Meeting were reviewed again following oral presentation. Topics representing new concepts, new or novel imaging techniques and instructive case series involving the musculoskeletal system, felt to be of potential interest to inves...
journal_title:Skeletal radiology
pub_type:
doi:10.1007/s00256-008-0531-7
更新日期:2009-01-01 00:00:00
abstract::Computed tomography is increasingly utilized for the evaluation of scaphoid fracture, nonunion, and deformity. We have developed a new technique of positioning patients while performing longitudinal computed tomography of the scaphoid. With the wrist positioned in radial deviation and neutral flexion, greater patient ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00198413
更新日期:1995-05-01 00:00:00
abstract::The case of a 17-year-old girl with sickle cell anaemia who presented with extensive osteomyelitis due to actinomycetes is reported. Osteomyelitis in the long bones due to actinomycosis is extremely rare. A review of the literature reveals only six cases in which actinomycetes have been isolated from lesions affecting...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00351352
更新日期:1984-01-01 00:00:00
abstract::In part I, we reviewed the varied clinical presentations, pathogenesis, histologic findings, radiologic findings, and treatment of intramedullary cartilaginous lesions of bone. In this section, we will evaluate our cases and consultations of juxtacortical cartilaginous tumors. Radiographic differential diagnosis inclu...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s002560050466
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To determine the ultrasonographic changes after steroid injection in carpal tunnel syndrome (CTS) and to evaluate the diagnostic value of ultrasound in post-treatment examination with clinical correlation. MATERIALS AND METHODS:Twenty-seven wrists with idiopathic CTS after a single injection of 40 mg of pred...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-017-2738-y
更新日期:2017-11-01 00:00:00
abstract::The original version of this article unfortunately contained mistake. Fig. 13a (Anatomy of the Ulnar Digital nerve of the Thumb) as originally published erroneously depicts the ulnar digital nerve of the thumb as a branch of the ulnar nerve. ...
journal_title:Skeletal radiology
pub_type: 杂志文章,已发布勘误
doi:10.1007/s00256-018-3037-y
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:High-resolution real-time three-dimensional (3D) imaging of the moving wrist may provide novel insights into the pathophysiology of joint instability. The purpose of this work was to assess the feasibility of using retrospectively gated spiral computed tomography (CT) to perform four-dimensional (4D) imaging ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-007-0374-7
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate whether ultrasound allows precise assessment of a focal defect at the lateral patellar retinaculum (LPR) and to determine its anatomical significance. MATERIALS AND METHODS:This work was initially undertaken in four cadaveric specimens and followed by high-resolution...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-019-03209-w
更新日期:2019-11-01 00:00:00
abstract::The deltoid is a fascinating muscle with a significant role in shoulder function. It is comprised of three distinct portions (anterior or clavicular, middle or acromial, and posterior or spinal) and acts mainly as an abductor of the shoulder and stabilizer of the humeral head. Deltoid tears are not infrequently associ...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-013-1667-7
更新日期:2013-10-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-009-0687-9
更新日期:2009-07-01 00:00:00
abstract::Chromomycosis is primarily a skin disease that superficially presents as slowly growing, verrucous lesions, often warty or cauliflower-like in appearance. It may occasionally create a flat, plaque-like lesion in the skin but deep-seated tumorous presentation has not previously been reported. As the lesion is limited t...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-008-0580-y
更新日期:2009-02-01 00:00:00
abstract::Over the past four decades, articular cartilage imaging has developed rapidly. Imaging now plays a critical role not only in clinical practice and therapeutic decisions but also in the basic research probing our understanding of cartilage physiology and biomechanics. ...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-011-1226-z
更新日期:2011-09-01 00:00:00
abstract::Langerhans cell histiocytosis (LCH) is an uncommon disorder of unknown etiology with a wide spectrum of biological behavior. The most common sites of involvement are bone, skin, and lung. While osseous LCH can result in secondary soft tissue involvement, primary soft tissue LCH in extremities with secondary bone invol...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-013-1611-x
更新日期:2013-09-01 00:00:00
abstract::Two patients with osteosarcoma of a lower limb and presumed lymph node metastases are described. The metastases presented in both children as palpable masses, one in the inguinal region and the other in the pelvis. One was visible on plain radiography; both were demonstrated on computed tomography and bone scintigraph...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00361209
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:To determine the accuracy of MR imaging for the evaluation of the subscapularis tendon as well as define imaging findings that will increase accuracy. MATERIALS AND METHODS:Retrospective review of the MR and operative (OR) reports of 286 patients was conducted and reviewed for the presence/degree (partial (P...
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doi:10.1007/s00256-013-1669-5
更新日期:2013-09-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00191523
更新日期:1993-01-01 00:00:00
abstract::Hypertrophy of the talar beak is the product of traction of the insertion of the joint capsule. It is commonly seen in athletes and may be entirely asymptomatic despite its size. It should not be mistaken for spurring of the articular margin of the talus which is seen in tarsal coalition. ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00350593
更新日期:1979-04-10 00:00:00
abstract::We report 8 cases of clear cell chondrosarcoma from 350 cases of chondrosarcoma (2.2%) seen at Istituto Rizzoli. The lesion is always low grade in nature and occurs in an epiphyseal location, usually in the proximal femur or humerus. This relatively inaccessible location may hinder the exact diagnosis. Wide resection ...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00241664
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:The present study aims to provide orientation for clinicians and radiologists to recognize the most prevalent findings leading to diagnosis in mucolipidosis from a description of the natural history of five Brazilian cases. MATERIALS AND METHODS:We conducted an observational and retrospective study of five p...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-019-3159-x
更新日期:2019-08-01 00:00:00
abstract::Soft tissue sarcomas (STS) are rare. Affected patients are at increased risk of developing a second primary malignancy, particularly another primary STS. These rarely affect the extremities, tending to occur in the abdomen, head or neck. We describe a patient with myxofibrosarcoma of the buttock who developed a second...
journal_title:Skeletal radiology
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更新日期:2011-08-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s002560050551
更新日期:1999-08-01 00:00:00
abstract::Behcet's disease is a chronic inflammatory condition involving several organs, such as the skin, mucous membranes, eyes, joints, intestines, lungs and central nervous system. It rarely affects the spinal column. We describe a case of progressive atlanto-axial subluxation in a 44-year-old woman with Behcet's disease. T...
journal_title:Skeletal radiology
pub_type: 杂志文章
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更新日期:2010-03-01 00:00:00
abstract::Primary liposarcoma of bone is exceedingly rare. We report a case of primary pleomorphic liposarcoma in the humerus of a 38-year-old female. Radiographs demonstrated an expansile and osteolytic lesion extending from the head to the proximal part of the shaft in the right humerus. MR study showed a defined lesion in th...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-005-0018-8
更新日期:2006-07-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-017-2625-6
更新日期:2017-08-01 00:00:00
abstract::A syndrome of hyperostosis of the thoracic wall, nonspecific signs of inflammatory disease, and palmar and plantar pustulosis is described in eight patients (Table 1). Seven had intersternocostoclavicular ossification, and one had chronic recurrent multifocal osteomyelitis. This complex of findings has been called "pu...
journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/BF00366761
更新日期:1989-01-01 00:00:00
abstract::Hip resurfacing arthroplasty is an increasingly common procedure for osteoarthritis. Conventional radiographs are used routinely for follow-up assessment, however they only provide limited information on the radiological outcome. Various complications have been reported in the scientific literature although not all ar...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-010-1081-3
更新日期:2011-07-01 00:00:00
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journal_title:Skeletal radiology
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更新日期:2012-02-01 00:00:00
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journal_title:Skeletal radiology
pub_type: 杂志文章
doi:10.1007/s00256-002-0503-2
更新日期:2002-08-01 00:00:00
abstract::Tuberculosis remains a major international health problem despite advances in radiological diagnosis and antituberculous therapy. Disseminated tuberculous infection affecting a single bone and manifested as multifocal lytic cortical lesions is rare and unusual. We report on a 50-year-old man with multifocal involvemen...
journal_title:Skeletal radiology
pub_type: 杂志文章,评审
doi:10.1007/s00256-003-0714-1
更新日期:2004-04-01 00:00:00