Abstract:
:Anal squamous dysplasia is recognized as a spectrum of disease that ranges from low-grade intraepithelial lesions (LSIL) to high-grade squamous intraepithelial lesions (HSIL) to invasive anal squamous cell carcinoma (SCC). Recent reports have shown a significant increase in both the incidence and prevalence of both HSIL and anal SCC, particularly in immunocompromised patients and in men who have sex with men. These lesions are associated with chronic infection with the human papillomavirus. The natural history is unknown, yet reports of untreated patients have shown progression rates of up to 50% in high risk patients. There are controversies as to the optimal management of patients with HSIL. However, there is evidence that screening of high-risk patients with anal cytology is useful in identifying those that require further evaluation. Examination of the anorectal region is enhanced with the use of high resolution anoscopy. Treatment modalities vary in terms of morbidity and success rates. Wide local excision is associated with significant morbidity. Newer therapies such as topical immunomodulation, photodynamic therapy and therapeutic vaccines have been proposed, but long-term follow-up is unavailable. High resolution anoscopy can be used in the office or in the operating room to direct therapy. Using a comprehensive approach of cytology and office-based and/or operating room procedures directed with high resolution anoscopy results in clearance of HSIL in up to 80% of patients, malignant progression in 1%, and less morbidity than wide local excision.
journal_name
Minerva Chirjournal_title
Minerva chirurgicaauthors
Pineda CE,Welton MLsubject
Has Abstractpub_date
2008-10-01 00:00:00pages
389-99issue
5eissn
0026-4733issn
1827-1626journal_volume
63pub_type
杂志文章,评审abstract::Following the exclusion of the ventilation of a lung, perfusion is arrested as a consequence of the Von Euler and Liljestrand vasoconstrictive reflex. However it is as yet unknown how long this phenomenon takes to manifest itself in human beings. In order to verify whether hypoxic pulmonary vasoconstriction follows im...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1993-06-15 00:00:00
abstract::The key concepts regarding nutrition of elderly patients prior to surgery are outlined. The main metabolic changes that occur during surgical stress, paying special attention to the characteristics of elderly patients, are described. Lastly, the caloric-energy intake required by postoperative geriatric patients is eva...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1999-01-01 00:00:00
abstract::Retrospective analysis of risk-factors in 241 patients with large abdominal incisional hernia collected in a 16-year period at the Department of Surgery, University of Pavia, allows the Authors to identify the aetiological mechanism of herniation and to discuss the fundamental technical skills in wall reconstruction. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1992-02-01 00:00:00
abstract::Acute aortic dissection (AAD) is an uncommon lethal cardiovascular emergency demanding prompt diagnosis and aggressive therapeutic intervention. Although it usually affects males over 60 years of age, it may also occur in young adults with specific risk factors such as Marfan syndrome, bicuspid aortic valve and larger...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2007-08-01 00:00:00
abstract::The role of some so-called primary and secondary (or oligo-elements) elements in the physiopathology of the cardiocirculatory system has been well known from a number of years and they have been regularly included in the treatment protocols. Some, including K, Ca, Mg and Zn, are extremely well known and widely used in...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract::A rare case of gastric schwannoma is reported. A 36-year-old woman whose endoscopy showed a mucosa tumor, biopsy findings were suggestive for leiomyoma. Diagnosis was made only with postoperative histology that revealed the benign schwannoma. Immunohistochemical staining showed positivity for S-100 protein and the neu...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1997-07-01 00:00:00
abstract::The early surgical reexploration to check the viability of intestinal loops in patients operated on for acute mesenteric ischaemia (the so called "second-look"), has contributed in improving the prognosis of this disease. However, since there are no certain predictive criteria for the progression of ischaemia, and not...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1997-05-01 00:00:00
abstract::The incidence of esophageal adenocarcinoma is on the rise. With advances in endoscopic techniques and imaging technology, early neoplastic lesions are being increasingly detected and treated. Managing early esophageal adenocarcinoma with endoscopic techniques is now considered the cornerstone of therapy, offering an a...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4733.18.07764-7
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Soft tissue defects are mostly managed surgically by free microvascular flaps. The progressive development of techniques and the availability and reliability of new different and free flaps encouraged this surgical approach. Thus, there is a constant need of free flap models to reproduce in laboratory. The e...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract::The management of patients with cervical injuries is highly controversial. Some authorities advocate mandatory exploration for all such injuries, while others advocate selective exploration. This paper will objectively review the evidence supporting each approach. The non-operative approach may be pursued through a va...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Obesity has an impact on health-related quality of life (HRQoL) and bariatric surgery may improve HRQoL in addition to severe obesity-related comorbidities. Aim of the study was to evaluate HRQoL following sleeve gastrectomy and the sensitivity of two HRQoL questionnaires: the Impact of Weight on Quality Of ...
journal_title:Minerva chirurgica
pub_type: 杂志文章,多中心研究
doi:
更新日期:2016-08-01 00:00:00
abstract::Following a review of the literature, the paper reports a case of duodenal injury. This rare pathology most frequently affects the second half of the organ and may cause damage ranging from a simple hematoma to parietal laceration with peritonitis and/or retroperitonitis. Symptoms are often confusing and delayed, and ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1991-09-15 00:00:00
abstract::Esophagectomy is a surgical operation which requires technical expertise to decrease the morbidity and mortality frequently associated with this advance procedure. Various minimally invasive esophagectomy techniques have been developed to decrease the negative impact of esophageal resection. Recently, robotic assisted...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2013-10-01 00:00:00
abstract::This paper is a critical review of the clinical records of 20 patients who underwent a Transduodenal Sphincteroplasty (PSP), from October 1990 to January 1992 at our Department (General Surgery). The age was 64.9 (14.2) years (mean and standard deviation), but 14 (70%) of those patients were older than 60 (range: 63 t...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract::A series of cases of acute pancreatitis treated between 1-XI-1972 and 1-XI-1975 is presented. A division is made between cases acute ab initio and postoperative pancreatitis, the latter further subdivided into pancreatic necroses, oedemas, and slight affections. The question of diagnosis is examined and elements indic...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1976-10-31 00:00:00
abstract::Between January 1989 and December 1994 we accomplished 130 CT-guided transthoracic fine needle aspirations (FNA) in 120 patients. Ten patients underwent a second FNA because of the negativity and doubts of the first. Diagnosis was targeted in 114 (95%) patients and 89% showed cytological evidence of malignancy. FNA-CT...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The authors report their experience on 313 liver transplantations performed in 255 patients. In 51.7% the indication to liver transplant was the cirrhosis, post alcoholic in 39.5% and post-hepatitis in 24.1%. The global mortality was 34.9% (89/255) with an actuarial survival of 53% at 74 months. We registered 10 cases...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1993-09-30 00:00:00
abstract::The aneurysm of the popliteal artery is the most commonly treated non-aortoiliac aneurysm, accounting for more than 70% of all peripheral aneurysms. The rupture of a popliteal aneurysm is rare and it is often misdiagnosed. In the case of a 46-year old female patient here reported, the patient was referred to our depar...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2012-08-01 00:00:00
abstract::In the present study the A. try to assess the usefulness of ultrasound in detecting blending risk in portal hypertension. Endoscopic and sonographic findings of 35 cirrhotic patients with esophageal varices were compared to a control group of 27 hepatopathy patients without portal hypertension, observed in the same de...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::The authors report a case of gastric leiomyoblastoma, a rare benign neoplasm that can sometimes undergo a malignant course. The main clinical an pathological issues are reviewed, in order to offer guidance as to the best suited surgical approach. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1992-11-01 00:00:00
abstract:AIM:Anorectal dysfunction is routinely treated at the Center for Pelvic Floor Rehabilitation, San Giovanni University Hospital, Turin, Italy. Of a total of 147 patients treated between April 2007 and May 2008, 44 (30%) received pelvic floor rehabilitation following anorectal surgery. With this study we wanted to evalua...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2009-04-01 00:00:00
abstract::The Authors report a case of benign mucocele which was brought to their attention for emergency treatment. Following a review of the literature, they examine the clinical, anatomopathological, pathogenetic and therapeutic problems related to this rare disease. In conclusion, it is important to assess the benign nature...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1990-10-31 00:00:00
abstract::Meckel's diverticulum occurs in approximately 2 percent of the population and may present at any age. Although Meckel's diverticulum may produce an intestinal obstruction or perforation, simulating an appendicitis, hemorrhage is its most important clinical presentation. From 1989 to 1994, Meckel's diverticulum was dis...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1997-12-01 00:00:00
abstract::Primitive tumor of the liver, associated with cirrhosis with 40-80% of incidence, isn't one of the most common malignant neoplasms in the western area but it holds low survival and diminished possibilities of radical exeresis. A few years ago it has enrolled several non-invasive imaging-guided techniques, alternative ...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1996-05-01 00:00:00
abstract::In the clinical office, during surgical planning, or in the operating room, neurosurgeons have been surrounded by the digital world either recreating old tools or introducing new ones. Technological refinements, chiefly based on the use of computer systems, have altered the modus operandi for neurosurgery. In the emer...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:2010-08-01 00:00:00
abstract::The authors make a wide-ranging review of the literature, examine the epidemiological aspect of fail chest and underline the importance of its correct anatomopathological classification for a more qualified physiopathologist, diagnostic and therapeutic approach. They make a historical excursion on volet's treatment an...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1994-03-01 00:00:00
abstract::Reference is made to the literature and personal experience in an assessment of the rôle of total parenteral nutrition in ulcerative colitis. An estimate is made of the position of this form of treatment with respect to conventional medical and surgical management, and its influence on the natural course of the diseas...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1979-01-15 00:00:00
abstract::The authors discuss the question of the reappearance of esophageal peristalsis following surgical or dilating treatment in patients with a diagnosis of cardiospasm. On the basis of their experience and an extensive review of the literature, the authors affirm that the reappearance of motor activity should not be attri...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1993-10-31 00:00:00
abstract::The paper describes a case of traumatic hernia of the diaphragm, complicated by mixed gastric volvulus, with a rapid onset and severe clinical symptoms. The etiopathogenesis, diagnosis and therapeutic methods inherent in this rare affliction are discussed. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1989-11-15 00:00:00
abstract:BACKGROUND:Procalcitonin (PCT) is a new marker for severe infection that is supposed to have a useful role in the early detection of bacterial infection in the perioperative period. AIM OF THE STUDY:to test the hypothesis that PCT is useful as an early marker of postoperative infectious complications. METHODS:Thirty-...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2002-02-01 00:00:00