当前位置： SCI文献检索 > BMC EVOLUTIONARY BIOLOGY期刊下所有文献 > Assortative mating and fragmentation within dog breeds.

Assortative mating and fragmentation within dog breeds.

Abstract：

BACKGROUND:There are around 400 internationally recognized dog breeds in the world today, with a remarkable diversity in size, shape, color and behavior. Breeds are considered to be uniform groups with similar physical characteristics, shaped by selection rooted in human preferences. This has led to a large genetic difference between breeds and a large extent of linkage disequilibrium within breeds. These characteristics are important for association mapping of candidate genes for diseases and therefore make dogs ideal models for gene mapping of human disorders. However, genetic uniformity within breeds may not always be the case. We studied patterns of genetic diversity within 164 poodles and compared it to 133 dogs from eight other breeds. RESULTS:Our analyses revealed strong population structure within poodles, with differences among some poodle groups as pronounced as those among other well-recognized breeds. Pedigree analysis going three generations back in time confirmed that subgroups within poodles result from assortative mating imposed by breed standards as well as breeder preferences. Matings have not taken place at random or within traditionally identified size classes in poodles. Instead, a novel set of five poodle groups was identified, defined by combinations of size and color, which is not officially recognized by the kennel clubs. Patterns of genetic diversity in other breeds suggest that assortative mating leading to fragmentation may be a common feature within many dog breeds. CONCLUSION:The genetic structure observed in poodles is the result of local mating patterns, implying that breed fragmentation may be different in different countries. Such pronounced structuring within dog breeds can increase the power of association mapping studies, but also represents a serious problem if ignored. In dog breeding, individuals are selected on the basis of morphology, behaviour, working or show purposes, as well as geographic population structure. The same processes which have historically created dog breeds are still ongoing, and create further subdivision within current dog breeds.

journal_name

BMC Evol Biol

journal_title

BMC evolutionary biology

authors

Björnerfeldt S,Hailer F,Nord M,Vilà C

doi

10.1186/1471-2148-8-28

subject

Has Abstract

pub_date

2008-01-28 00:00:00

pages

issn

1471-2148

pii

1471-2148-8-28

journal_volume

pub_type

杂志文章

在线工具

Assortative mating and fragmentation within dog breeds.