Decreases in CD8+ T, naive (CD4+CD45RA+) T, and B (CD19+) lymphocytes by exposure to manganese fume.

Abstract:

:To examine the effects of exposure to manganese (Mn) on the cellular and humoral immune system in men, T lymphocyte subpopulations, B (CD19+) lymphocytes, natural killer (NK) cells, and serum immunoglobulins (i.e., IgG, IgA and IgM) together with total T (CD3+) lymphocytes and total lymphocytes were measured in blood samples from 21 welders mainly exposed to Mn fume with blood Mn (BMn) concentrations of 0.6-2.3 (mean 1.4) microg/dl and 21 healthy controls working in the same factory (BMn concentrations: 0.7 to 1.7, mean 1.1 microg/dl). The workers engaged in welding for 6 to 36 (mean 17) yr. All the study subjects were divided into 3 equally sized groups (n=14 for each group) according to BMn concentrations. Numbers of CD8+ T, total T (CD3+), B (CD19+), and total lymphocytes were significantly lower in high-BMn group than those in low-BMn group; the numbers of CD8+ T lymphocytes were significantly lower in moderate-BMn group compared to low-BMn group. After adjusting for age and smoking, significant inverse correlations between BMn concentrations and CD4+CD45RA+ T, CD4+ T, CD8+ T, CD3+ T, and total lymphocytes were found. We conclude that T lymphocytes, especially CD8+ and CD4+CD45RA+ T lymphocytes, as well as CD19+ B lymphocytes are affected by exposure to Mn fume.

journal_name

Ind Health

journal_title

Industrial health

authors

Nakata A,Araki S,Park SH,Park JT,Kim DS,Park HC,Yokoyama K

doi

10.2486/indhealth.44.592

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

592-7

issue

4

eissn

0019-8366

issn

1880-8026

pii

JST.JSTAGE/indhealth/44.592

journal_volume

44

pub_type

杂志文章
  • Measurement of dioxins in human blood: improvement of analytical method.

    abstract::We have improved the method of measuring dioxins in the blood of Yusho patients; with this improved method, it is possible to take measurements quickly and precisely, using as little as 5g of blood. The specific points of improvement of this method are the extraction of lipids from blood by accelerated solvent extract...

    journal_title:Industrial health

    pub_type: 杂志文章,评审

    doi:10.2486/indhealth.41.197

    authors: Iida T,Todaka T

    更新日期:2003-07-01 00:00:00

  • Exposure reconstruction of trichloroethylene among patients with occupational trichloroethylene hypersensitivity syndrome.

    abstract::Occupational trichloroethylene (TCE) exposure can induce life-threatening generalized dermatitis accompanied by hepatitis: TCE hypersensitivity syndrome (HS). Since the patients' exposure levels have not been fully clarified, this study estimated end-of-shift urinary concentrations of trichloroacetic acid (TCA) and th...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.2017-0202

    authors: Nakajima T,Wang H,Ito Y,Naito H,Wang D,Zhao N,Li H,Qiu X,Xia L,Chen J,Wu Q,Li L,Huang H,Kamijima M

    更新日期:2018-07-27 00:00:00

  • Respiratory morbidity induced by occupational inhalation exposure to formaldehyde.

    abstract::The potential of formaldehyde to produce chronic respiratory tract disease remains a controversial issue. The main purpose of this study was to investigate the respiratory effects, if any, of long term occupational exposure to formaldehyde. This cross-sectional study was carried out at a local melamine-formaldehyde re...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.ms1197

    authors: Neghab M,Soltanzadeh A,Choobineh A

    更新日期:2011-01-01 00:00:00

  • Biomechanical and physiological analyses of a luggage-pulling task.

    abstract::The purpose of this study was to identify the degree of physical stresses on two-wheeled carry-on luggage users in terms of biomechanics and work physiology. Based on 3D kinematics, a 3D inverse dynamic biomechanical model having fifteen segments was developed to evaluate a one-hand pulling task. Joint reaction forces...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.45.756

    authors: Jung MC,Haight JM,Hallbeck MS

    更新日期:2007-12-01 00:00:00

  • Maximum acceptable weight of manual load carriage for young Taiwanese males.

    abstract::This study examined the maximum acceptable weight of carriage (MAWC) for young Taiwanese males experienced in manual load carriage tasks. The elements of the examined load carriage tasks included lifting a box from the floor to the waist height, turning around while holding the box, carrying the box at the waist heigh...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.44.200

    authors: Cheng TS,Lee TH

    更新日期:2006-01-01 00:00:00

  • Work-related cerebrovascular and cardiovascular diseases (WR-CVDs) in Korea.

    abstract::The effects of work on the heart are mediated by chemical, physical, and psychological stressors. It is standard clinical practice to assess personal risk factors such as cigarette smoking, hypertension, and cholesterol. Evaluation of a patient's acute symptoms and activity level at the time of presentation is also st...

    journal_title:Industrial health

    pub_type: 杂志文章,评审

    doi:10.2486/indhealth.ms1191

    authors: Park J,Kim Y,Hisanaga N

    更新日期:2011-01-01 00:00:00

  • Association of active and passive smoking with occupational injury in manual workers: a cross-sectional study of the 2011 Korean working conditions survey.

    abstract::This study was conducted to investigate the relationship of active and passive smoking with occupational injury among manual workers. Data from the 2011 Korean Working Conditions Survey were analyzed for 12,507 manual workers aged ≥15 yr. Overall, 60.4% of men and 5.8% of women were current smokers. The prevalence of ...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.2015-0011

    authors: Kim HC,Lamichhane DK,Jung DY,Kim HR,Choi EH,Oh SS,Kang HT,Rhee KY,Chang SJ

    更新日期:2015-01-01 00:00:00

  • The nighttime nap strategies for improving night shift work in workplace.

    abstract::Nighttime napping is an effective measure to prevent adverse effects due to night shift work. A characteristic of nighttime nap is that it can result in considerably deeper sleep. Several studies have shown that taking nighttime naps suppressed increasing sleepiness, decreasing alertness during the period following aw...

    journal_title:Industrial health

    pub_type: 杂志文章,评审

    doi:10.2486/indhealth.43.24

    authors: Takeyama H,Kubo T,Itani T

    更新日期:2005-01-01 00:00:00

  • Postures and movements in the most common tasks of power line workers.

    abstract::The repair and maintenance of electrical power lines involves awkward postures, which are known risk factors for developing musculoskeletal disorders. The aim of the present study was to quantify postures and movements of upper arm, head, upper back and neck in the main tasks performed by line workers. Posture of twel...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.ms1252

    authors: Moriguchi CS,Carnaz L,Alencar JF,Miranda Júnior LC,Granqvist L,Hansson GÅ,Gil Coury HJ

    更新日期:2011-01-01 00:00:00

  • Case study on possible falling patterns of a fatal fall from stairs.

    abstract::Considering a fatal case of an aged individual, who died due to falling down stairs, the cause of the fatal fall was investigated through experiments. A witness, who was with the victim, when the fatal accident occurred, stated that the aged individual had miss-footed, lost balance at the top of the stairs, and fell a...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.2014-0092

    authors: Nagata H

    更新日期:2014-01-01 00:00:00

  • Absence of mutagenicity in peripheral lymphocytes of workers occupationally exposed to methyl methacrylate.

    abstract::Chromosome aberration rates and sister chromatid exchange frequency were examined in the peripheral lymphocytes of 38 male workers who were engaged in organic glass production and exposed to methyl methacrylate (MMA) vapors at the concentrations of 0.9 ppm to 71.9 ppm. The results were compared with the findings in th...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.32.97

    authors: Seiji K,Inoue O,Kawai T,Mizunuma K,Yasugi T,Moon CS,Takeda S,Ikeda M

    更新日期:1994-01-01 00:00:00

  • Hazardous workplace review program in Taiwan.

    abstract::In Taiwan, relevant mid-term plans and projects of mitigating occupational hazards have been launched in recent years in the hopes of lowering the incidence of occupational hazards. In light of the lack of objective methodologies for researches on issues pertaining occupational safety and health, this research aims to...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.2012-0053

    authors: Chang YK,Chuang KY,Tseng JM,Lin FC,Su TS

    更新日期:2013-01-01 00:00:00

  • Occupational hypersensitivity pneumonitis reported to the Czech National Registry Of Occupational Diseases in the period 1992-2005.

    abstract::Between 1992 and 2005, 72 cases of occupational hypersensitive pneumonitis were reported to the Czech National Registry of Occupational Diseases. This represented 0.24% of all occupational diseases reported in the Czech Republic during that period. The greatest number of cases occurred in 1997 (10 cases), of which men...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.47.443

    authors: Fenclová Z,Pelclová D,Urban P,Navrátil T,Klusácková P,Lebedová J

    更新日期:2009-08-01 00:00:00

  • Exposure to organic solvents among handicraft car painters: A pilot study in Italy.

    abstract::Car repair painters usually experience long-term exposure to many different solvents. In Italy, the greater part of car painting shops are "handicraft", i.e. 2-5 workers and small premises. Usually workers do not have specific duties, but everyone takes part in all different operations. Moreover, working time is not s...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.44.310

    authors: Vitali M,Ensabella F,Stella D,Guidotti M

    更新日期:2006-04-01 00:00:00

  • Job dissatisfaction as a contributor to stress-related mental health problems among Japanese civil servants.

    abstract::Although studies on the association of job dissatisfaction with mental health have been conducted in the past, few studies have dealt with the complicated links connecting job stress, job dissatisfaction, and stress-related illness. This study seeks to determine how job dissatisfaction is linked to common mental healt...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.2012-0058

    authors: Tatsuse T,Sekine M

    更新日期:2013-01-01 00:00:00

  • Precarious employment and health: analysis of the Comprehensive National Survey in Japan.

    abstract::Recent studies suggest that unstable employment contracts may affect the health of workers. Many Japanese workers working full time in ostensibly permanent positions actually operate within unstable and precarious employment conditions. We compared the health status of Japanese workers with precarious employment contr...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.ms1260

    authors: Tsurugano S,Inoue M,Yano E

    更新日期:2012-01-01 00:00:00

  • Genotoxic effects in workers exposed to benzene: with special reference to exposure biomarkers and confounding factors.

    abstract::The aim of the study was to establish a correlation between biomarkers of exposure and cytogenetic test results in workers occupationally exposed to benzene and toluene, with special reference to confounding factors influencing the outcome of the cytogenetic test. The incidence of structural chromosome aberrations and...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.35.367

    authors: Bogadi-Sare A,Brumen V,Turk R,Karacić V,Zavalić M

    更新日期:1997-07-01 00:00:00

  • Less quick returns--greater well-being.

    abstract::The aim of this study was to design ergonomically improved shift schedules for nurses in primary health care shift work in order to enhance their health and well-being. The main change made was the reduction of quick returns (i.e., no more morning shifts immediately after an evening shift) in order to ensure more reco...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.mssw-02

    authors: Hakola T,Paukkonen M,Pohjonen T

    更新日期:2010-01-01 00:00:00

  • The economic impact of loss of performance due to absenteeism and presenteeism caused by depressive symptoms and comorbid health conditions among Japanese workers.

    abstract::We aimed to determine the economic impact of absenteeism and presenteeism from five conditions potentially comorbid with depressive symptoms-back or neck disorders, depression, anxiety, or emotional disorders, chronic headaches, stomach or bowel disorders, and insomnia-among Japanese workers aged 18-59 yr. Participant...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.2013-0016

    authors: Wada K,Arakida M,Watanabe R,Negishi M,Sato J,Tsutsumi A

    更新日期:2013-01-01 00:00:00

  • Intragroup and intergroup conflict at work, psychological distress, and work engagement in a sample of employees in Japan.

    abstract::The possible associations of intragroup and intergroup conflict at work with psychological distress and work engagement were investigated in a cross-sectional study in a manufacturing factory in Japan. A self-administered questionnaire was sent to all employees, and 255 responses were returned (a response rate of 84%)...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.47.640

    authors: Tsuno K,Kawakami N,Inoue A,Ishizaki M,Tabata M,Tsuchiya M,Akiyama M,Kitazume A,Kuroda M,Shimazu A

    更新日期:2009-12-01 00:00:00

  • Harmonizing work with the treatment and prevention of sleep disordered breathing in commercial motor vehicle drivers: implications for health and productivity management.

    abstract::The desastrous traffic accidents to date have provided the relevance for promotion of harmonization of work with treatment and prevention of sleep disordered breathing (SDB) in transport sectors. SDB is highly prevalent in commercial motor vehicle (CMV) drivers and is one cause of cognitive impairment and consequent t...

    journal_title:Industrial health

    pub_type: 杂志文章,评审

    doi:10.2486/indhealth.2018-0083

    authors: Wada H,Kimura M,Shirahama R,Tajima T,Maruayama K,Endo M,Ikeda A,Tanigawa T

    更新日期:2019-02-05 00:00:00

  • Magnetometric evaluation of the effects of gallium arsenide on the clearance and relaxation of iron particles.

    abstract::Intratracheal instillation of GaAs suspension has been histopathologically shown to induce a diffuse pulmonary response. In the present study, magnetometry was used to evaluate the effects of intratracheally instilled GaAs on the behavior of externally magnetized iron particles instilled in rabbit lung. Magnetometric ...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.31.143

    authors: Aizawa Y,Takata T,Karube H,Tatsumi H,Inokuchi N,Kotani M,Chiyotani K

    更新日期:1993-01-01 00:00:00

  • Involvement of caspase 3 mediated apoptosis in hematopoietic cytotoxicity of metabolites of ethylene glycol monomethyl ether.

    abstract::The hematopoietic toxicity of ethylene glycol monomethyl ether (EGME) and its metabolites, methoxy acetaldehyde (MALD) and methoxyacetic acid (MAA), was analyzed using human bone marrow cells from a lymphoma patient without bone marrow involvement and a human leukemia cell line, HL60. After 24-hour incubation, the con...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.40.371

    authors: Takagi A,Yamada T,Hayashi K,Nakade Y,Kojima T,Takamatsu J,Shibata E,Ichihara G,Takeuchi Y,Murate T

    更新日期:2002-10-01 00:00:00

  • A prospective observation of onsets of health defects associated with working hours.

    abstract::A prospective study examined whether working 50 hours or less per week was associated with an increase of mental and circulatory disorders, and if so, whether it was significant for managing workers' health. White-collar workers aged 20 to 60 working at an office of a Japanese company were surveyed from August 1997 to...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.41.101

    authors: Tarumi K,Hagihara A,Morimoto K

    更新日期:2003-04-01 00:00:00

  • Time domain detection of shocks and impacts in whole-body vibration.

    abstract::A method for detecting shocks and impacts in whole-body vibration time histories has been developed that is suitable for implementation as a computer algorithm. The procedure consists of comparing the magnitudes of a higher-order mean value and the impulsiveness calculated for successive time segments of the accelerat...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.mswbvi-01

    authors: Brammer AJ,Roddan G,Morrison JB

    更新日期:2010-01-01 00:00:00

  • Does cognitive function predict changes in perception of stressful working conditions?

    abstract::Cognitive health is a key resource for individuals to nurture their employability. We studied the longitudinal association of cognitive function with changes in stressful working conditions, testing a possible reversed causation. We used a sample of employees (N=1,355) participating in two surveys (2006 and 2011) with...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.2019-0017

    authors: Li J,Wege N,Loerbroks A,Riedel N

    更新日期:2020-02-04 00:00:00

  • Heat stress standard ISO 7243 and its global application.

    abstract::This paper presents heat stress Standard ISO 7243, which is based upon the wet bulb globe temperature index (WBGT), and considers its suitability for use worldwide. The origins of the WBGT index are considered and how it is used in ISO 7243 and across the world as a simple index for monitoring and assessing hot enviro...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.44.368

    authors: Parsons K

    更新日期:2006-07-01 00:00:00

  • Relationship between depressive symptoms and perceived individual level occupational stress among Japanese schoolteachers.

    abstract::Japanese teachers are mentally and physically burdened with various work stressors. This cross-sectional study examined the relationship between depressive symptoms and perceived individual level occupational stress including role problems among Japanese schoolteachers. This study included 1,006 teachers working in pu...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.2015-0195

    authors: Nakada A,Iwasaki S,Kanchika M,Nakao T,Deguchi Y,Konishi A,Ishimoto H,Inoue K

    更新日期:2016-10-08 00:00:00

  • Lung cancer probably related to talc exposure: a case report.

    abstract::Industrial talc has been widely circulated in the world for a long time. The pure talc has little effects on humans, but inhalation of talc contaminated with asbestos can causes severe asbestos-related diseases such as lung cancer and malignant mesothelioma. Herein, we represent a case of lung cancer after occupationa...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.ms1385

    authors: Kim J,Oak C,Jang T,Jung M,Chun B,Park EK,Takahashi K

    更新日期:2013-01-01 00:00:00

  • Exposure to airborne endotoxin in Italian greenhouses: environmental analyses.

    abstract::The peculiar characteristics of the greenhouses as confined spaces, microclimate and poor air exchange with the outside environment, encourage the development of a large number of biological agents. Endotoxin, is probably a major causative agent of occupational health problems. The objective of this study was to measu...

    journal_title:Industrial health

    pub_type: 杂志文章

    doi:10.2486/indhealth.2017-0080

    authors: Gioffrè A,Marramao A,Gesu ID,Samele P,Paba E,Marcelloni AM,Chiominto A,Iavicoli S

    更新日期:2018-04-07 00:00:00