Clinically relevant cholesterol elevation in anxiety disorders: a comparison with normal controls.

Abstract:

:Recently, several studies reported elevated cholesterol levels in panic disorder, agoraphobia, and general anxiety disorder, but the clinical relevance is still unsettled. All studies so far have disregarded the possible influence of dietary and physical exercise factors. In this study, 30 patients with different anxiety disorders and 30 normal controls were compared for total cholesterol, low-density lipoprotein (LDL), and cholesterol high-density lipoprotein (HDL) ratio. Dietary and physical exercise habits were measured by self-rating questionnaires. Patients with anxiety disorders had significantly elevated total cholesterol, LDL, and cholesterol/HDL ratios. Patients showed borderline-high or high cholesterol levels almost 3 times as often as control participants. Anxiety-specific avoidance of physical exercise and special dietary habits of anxiety patients had a significant but minor impact on differences in cholesterol between both groups. Our data support the assumption that serum cholesterol elevations in anxiety disorder patients are within a clinically relevant range.

journal_name

Int J Behav Med

authors

Peter H,Goebel P,Müller S,Hand I

doi

10.1207/s15327558ijbm0601_3

keywords:

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

30-9

issue

1

eissn

1070-5503

issn

1532-7558

journal_volume

6

pub_type

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