Efficacy and safety of the covered Wallstent in patients with distal malignant biliary obstruction.

Abstract:

BACKGROUND:The aim of this study was to evaluate the efficacy and the safety of the covered Wallstent, a commercially available silicone-covered, self-expandable metallic stent (covered Wallstent), for the treatment of distal malignant biliary obstruction. METHODS:Sixty-nine consecutive patients with unresectable distal malignant biliary obstruction who underwent covered Wallstent placement between October 2001 and October 2003 were studied at 4 affiliated hospitals. RESULTS:Mean stent patency and mean survival were 139.1 days and 200.9 days, respectively. Stent occlusion occurred in 7 cases (10.1%), but tumor ingrowth was not observed. Seventeen complications, including 5 cholangitis (7.2%), 4 stent migration (5.8%), 4 cholecystitis (5.8%), and 4 pancreatitis (5.8%) were observed in 16 patients (23.2%). Stent misplacement was observed in 7 patients (10.1%). CONCLUSIONS:Covered Wallstent is effective in preventing tumor ingrowth for the treatment of distal malignant biliary obstruction. However, the overall complication rate may be higher than uncovered self-expanding metal stents and covered self-expanding metal stents of different design.

journal_name

Gastrointest Endosc

authors

Nakai Y,Isayama H,Komatsu Y,Tsujino T,Toda N,Sasahira N,Yamamoto N,Hirano K,Tada M,Yoshida H,Kawabe T,Omata M

doi

10.1016/j.gie.2005.06.030

keywords:

subject

Has Abstract

pub_date

2005-11-01 00:00:00

pages

742-8

issue

5

eissn

0016-5107

issn

1097-6779

pii

S0016-5107(05)02293-5

journal_volume

62

pub_type

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