Dynamics of annual influenza A epidemics with immuno-selection.

Abstract:

:The persistence of Influenza A in the human population relies on continual changes in the viral surface antigens allowing the virus to reinfect the same hosts every few years. The epidemiology of such a drifting virus is modeled by a discrete season-to-season map. During the epidemic season only one strain is present and its transmission dynamics follows a standard epidemic model. After the season, cross-immunity to next year's virus is determined from the proportion of hosts that were infected during the season. A partial analysis of this map shows the existence of oscillations where epidemics occur at regular or irregular intervals.

journal_name

J Math Biol

authors

Andreasen V

doi

10.1007/s00285-002-0186-2

keywords:

subject

Has Abstract

pub_date

2003-06-01 00:00:00

pages

504-36

issue

6

eissn

0303-6812

issn

1432-1416

journal_volume

46

pub_type

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