当前位置： SCI文献检索 > MEDICAL SCIENCE MONITOR期刊下所有文献 > Human cytomegalovirus infection is associated with essential hypertension in Kazakh and Han Chinese populations.

Human cytomegalovirus infection is associated with essential hypertension in Kazakh and Han Chinese populations.

Abstract：

BACKGROUND:We aimed to study the association between cytomegalovirus (CMV) infection and hypertension in Kazakh and Han populations from Xinjiang Province, China. MATERIAL/METHODS:We analyzed data on 800 Kazakhs (467 hypertension patients and 333 healthy control participants) and 800 Hans (482 hypertension patients and 318 healthy control participants) aged 18-84 years old. ELISA and real-time quantitative PCR coupled with restriction fragment length polymorphism analysis were applied for determining CMV infection and glycoprotein B (gB) genotypes, respectively. RESULTS:Serologic evidence of CMV infection was obtained for 95.4% and 90.1% of the Kazakhs and Hans, respectively. The CMV seroprevalence rates among the Kazakh and Han participants with hypertension were 96.8% and 89.8%, respectively. Multiple logistic regression analyses revealed statistically significant independent associations between CMV seropositivity and hypertension in Kazakh males and between CMV antibody titers and hypertension in Hans; significant relationships also existed between CMV antibody titers and blood pressure in Hans. In Kazakhs, 3 CMV gB genotypes were identified: gB2 and genotype mixtures gB1+gB2 and gB2+gB3. In Hans, 4 CMV gB genotypes were identified: gB1, gB2, gB1+gB2, and gB2+gB3. Of the 4 studied genotypes, gB2+gB3 showed a significant independent association with hypertension in Kazakh females. CONCLUSIONS:CMV infection is associated with essential hypertension in Kazakh males and Hans in Xinjiang. CMV seropositivity is associated with hypertension in Kazakh males, and CMV antibody titers are associated with blood pressure and hypertension in Han males and females. Moreover, the CMV gB2+gB3 genotype mixture is associated independently with essential hypertension in Kazakh females.

journal_name

Med Sci Monit

journal_title

Medical science monitor : international medical journal of experimental and clinical research

authors

Tang N,Li JW,Liu YM,Zhong H,Wang LM,Deng FM,Qu YY,Hui J,Cheng J,Tang B,Huang G,Guo SX,Li XZ,Wei LL,He F

doi

10.12659/MSM.892861

subject

Has Abstract

pub_date

2014-12-02 00:00:00

pages

2508-19

eissn

1234-1010

issn

1643-3750

pii

892861

journal_volume

20

pub_type

杂志文章

相关文献

MEDICAL SCIENCE MONITOR文献大全
  • Increased plasma peroxides as a marker of oxidative stress in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).

    abstract：BACKGROUND:There is evidence that myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by activation of immune, inflammatory, oxidative and nitrosative stress (IO&NS) pathways. The present study was carried out in order to examine whether ME/CFS is accompanied by increased levels of plasma perox...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/msm.881699

    authors： Maes M,Kubera M,Uytterhoeven M,Vrydags N,Bosmans E

    更新日期：2011-04-01 00:00:00

  • Factors influencing the surgical process during shoulder joint replacement: time-action analysis of five different prostheses and three different approaches.

    abstract：BACKGROUND:To evaluate the per-operative process of shoulderjoint replacement, time-action analysis can be used. MATERIAL/METHODS:Forty procedures performed by 7 surgeons with different experience using 5 different prostheses and 3 different surgical approaches were analyzed. RESULTS:The surgical procedures showed a ...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：

    authors： Minekus JP,Valstar ER,Rozing PM,de Voss MJ,Diercks RL,Willems WJ,Dankelman J

    更新日期：2005-01-01 00:00:00

  • Does G2677T Polymorphism of the MDR1 Gene Make a Difference in the Therapeutic Response to Paroxetine in Depressed Patients in a Slovakian Population?

    abstract：:BACKGROUND The role of multidrug resistance 1 gene (MDR1 or ABCB1) polymorphism G2677T was studied in relation to paroxetine therapeutic efficacy and its side effects, as well as its association with selected demographic and clinical characteristics of patients with depressive disorder. MATERIAL AND METHODS To evaluat...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/MSM.907434

    authors： Vancova Z,Cizmarikova M,Dragasek J,Zofcakova S,Kolarcik P,Mojzis J

    更新日期：2018-05-13 00:00:00

  • Serum leptin levels in acromegaly--a significant role for adipose tissue and fasting insulin/glucose ratio.

    abstract：BACKGROUND:Leptin plays an important role in controlling satiety and maintaining energy balance. Acromegaly is characterized by decreased fat, which increases after the disease is cured. Our objective was to investigate serum leptin in acromegaly in terms of disease activity, body fat content, insulin and glucose level...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：

    authors： Bolanowski M,Milewicz A,Bidzińska B,Jedrzejuk D,Daroszewski J,Mikulski E

    更新日期：2002-10-01 00:00:00

  • Comparison of Role of Hand and Wrist Ultrasound in Diagnosis of Subclinical Synovitis in Patients with Systemic Lupus Erythematosus and Rheumatoid Arthritis: A Retrospective, Single-Center Study.

    abstract：:BACKGROUND This retrospective study aimed to compare the roles of hand and wrist ultrasound in diagnosing subclinical synovitis in patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) at a single center in Sichuan, China. MATERIAL AND METHODS Forty-one patients with SLE and 20 patients with R...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/MSM.926436

    authors： Tang H,Liu Y,Liu Y,Zhao H

    更新日期：2020-12-12 00:00:00

  • Altered Dynamic Neural Activity in the Default Mode Network in Lung Cancer Patients After Chemotherapy.

    abstract：:BACKGROUND Few studies have examined functional brain changes specifically associated with chemotherapy (CTx) in patients with lung cancer. This prospective longitudinal research aimed to explore the change in intrinsic brain activity by investigating patients with lung cancer after CTx. MATERIAL AND METHODS Sixteen p...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/MSM.921700

    authors： You J,Hu L,Zhang Y,Chen F,Yin X,Jin M,Chen YC

    更新日期：2020-02-18 00:00:00

  • Antioxidant vitamin C prevents decline in endothelial function during sitting.

    abstract：BACKGROUND:This study was designed to test the hypothesis that antioxidant Vitamin C prevents the impairment of endothelial function during prolonged sitting. MATERIAL AND METHODS:Eleven men (24.2 ± 4.4 yrs) participated in 2 randomized 3-h sitting trials. In the sitting without vitamin C (SIT) and the sitting with vi...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章,随机对照试验

    doi：10.12659/MSM.893192

    authors： Thosar SS,Bielko SL,Wiggins CC,Klaunig JE,Mather KJ,Wallace JP

    更新日期：2015-04-07 00:00:00

  • Type 1 diabetes: evidence of interaction between ACP1 and ADA1 gene polymorphisms.

    abstract：BACKGROUND:ACP1 (acid phosphatase locus 1, a cytosolic low-molecular-weight phosphotyrosin phosphatase) and ADA1 (adenosine deaminase locus 1) are two polymorphic systems involved in immune reactions. Observed interactions at the biochemical and clinical levels between the two systems prompted this investigation of a p...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：

    authors： Saccucci P,Manca Bitti ML,Bottini N,Rapini N,Piccinini S,D'Annibale F,Chiarelli F,Verrotti A,Bottini E,Gloria-Bottini F

    更新日期：2009-10-01 00:00:00

  • Higher Concentration of Hypertonic Saline Shows Better Recovery Effects on Rabbits with Uncontrolled Hemorrhagic Shock.

    abstract：:BACKGROUND Our previous study found a novel fluid combination with better resuscitation effects under hypotensive condition at the early stage of uncontrolled hemorrhagic shock (UHS). However, the optimal recovery concentration of hypertonic saline in this fluid combination remains unknown. This experiment aimed to ex...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/MSM.916937

    authors： Xu L,Kang F,Hu W,Liu X

    更新日期：2019-10-30 00:00:00

  • Ureteroscopic Diagnosis and Povidone Iodine Treatment for Chronic Unilateral Hematuria Caused by Benign Lesions.

    abstract：:BACKGROUND The management of chronic unilateral hematuria (CUH) caused by benign lesions is a therapeutic challenge to many urologists. The aims of this study were to evaluate the efficacy and safety of povidone iodine sclerotherapy for CUH. MATERIAL AND METHODS We identified 20 patients who underwent povidone iodine ...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/MSM.923552

    authors： Hu Z,Zhang Y,Liu J,Wu H,Wang F,Jin X

    更新日期：2020-07-21 00:00:00

  • Neopterin as a prognostic marker in patients with chronic heart failure.

    abstract：BACKGROUND:The study aimed at evaluating neopterin concentration in relation to heart failure etiology and determining basal neopterin concentration in relation to the clinical state of patients after 12 months of standard treatment. MATERIAL/METHODS:The examined group was composed of 47 patients with NYHA class II an...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：

    authors： Wietlicka-Kokoszanek I,Jablecka A,Smolarek I,Bogdanski P,Chmara E,Korzeniowska K,Kazmierczak M,Kazmierczak E,Musialik K

    更新日期：2010-05-01 00:00:00

  • Progress of the Anterior Transpedicular Screw in Lower Cervical Spine: A Review.

    abstract：:The anterior transpedicular screws (ATPS) fixation is a valuable discovery in the field of lower cervical spine (LCS) reconstruction, as it has the advantages of both anterior and posterior approaches. In recent years, with in-depth research on ATPS fixation related to anatomy, biomechanical tests, and clinical applic...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章,评审

    doi：10.12659/MSM.918061

    authors： Zhang YW,Zeng T,Gao WC,Xiao X,Xiao Y,Chen X,Zhang SL,Deng L

    更新日期：2019-08-21 00:00:00

  • Soluble cytokine receptors in renal vasculitis and lupus nephritis.

    abstract：BACKGROUND:The activation of various cytokines, e.g. TNFalpha, IL-1 and/or IL-6, may play an important role in the pathogenesis of renal vasculitis and lupus nephritis (LN). The systemic effect of these cytokines may be modulated by their circulating soluble receptors. The plasma levels of cytokine receptors may thus a...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：

    authors： Tesar V,Jirsa M Jr,Zima T,Kalousová M,Bartunková J,Stejskalová A,Dostál C,Zabka J

    更新日期：2002-01-01 00:00:00

  • Integrating theories of the etiology of Crohn's disease. On the etiology of Crohn's disease: questioning the hypotheses.

    abstract：:The most prominent theory describes the Crohn's Syndrome as a dysregulated, inappropriate immune response to otherwise innocuous bowel flora in a genetically susceptible host. The autoimmune theory assumes that a specific infectious agent does not exist. Data from mouse models, impairment of the mucosal epithelial bar...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章,评审

    doi：

    authors： Chamberlin WM,Naser SA

    更新日期：2006-02-01 00:00:00

  • Successful treatment of a critical burn patient with obstinate hyperglycemia and septic shock from pan-drug-resistant strains.

    abstract：BACKGROUND:The treatment of critical burn patients involves fluid resuscitation, homeostasis, prevention of infection, support and maintenance of organ functions, nutritional support, and wound repair. Correct management of these problems is a fierce challenge facing burn clinicians. This report presents a critical bur...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：

    authors： Xiao SC,Zhu SH,Xia ZF,Ma B,Cheng DS

    更新日期：2009-11-01 00:00:00

  • Does maternal height affect triplets' birth weight?

    abstract：BACKGROUND:In cases of triplet gestation where patients are reluctant to undergo multifetal pregnancy reduction, it would be helpful to identify predictive factors regarding poor or better outcomes. One such possible factor may be maternal height, which is possibly predictive of gestational age and neonatal birth weigh...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：

    authors： Blumenfeld Z,Lowenstein L,Brook O,Gonen R,Ophir E,Samueloff A

    更新日期：2006-01-01 00:00:00

  • Hypoxia-Induced Activation of JAK/STAT3 Signaling Pathway Promotes Trophoblast Cell Viability and Angiogenesis in Preeclampsia.

    abstract：:BACKGROUND To explore the effect of hypoxic preconditioning on the JAK/STAT3 signaling pathway and its effect on trophoblast cell viability and angiogenesis in preeclampsia (PE). MATERIAL AND METHODS Placental tissues from normal pregnant women and PE patients were collected to detect the expression levels of JAK and ...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/msm.905418

    authors： Xu C,Li X,Guo P,Wang J

    更新日期：2017-10-14 00:00:00

  • Apamin/charybdotoxin-sensitive endothelial K+ channels contribute to acetylcholine-induced, NO-dependent vasorelaxation of rat aorta.

    abstract：BACKGROUND:Activation of endothelial K+ channels and the subsequent increase in intracellular Ca2+, may be an important step in the release of relaxant factors in response to endothelium-dependent vasodilator agents. However, the type of K+ channel involved in hyperpolarization of the endothelium and the subsequent rel...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：

    authors： Qiu Y,Quilley J

    更新日期：2001-11-01 00:00:00

  • A Bibliometric Analysis Using CiteSpace of Publications from 1999 to 2018 on Patient Rehabilitation After Total Knee Arthroplasty.

    abstract：:BACKGROUND Following total knee arthroplasty (TKA), postoperative patient rehabilitation is important to achieve the optimal level of knee function and mobility. Clinical research in this field is growing, and bibliometric analysis of publication may provide direction for research clinicians and raise awareness of res...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/MSM.920795

    authors： Wang SQ,Gao YQ,Zhang C,Xie YJ,Wang JX,Xu FY

    更新日期：2020-03-17 00:00:00

  • A novel hypothesis: the application of platelet-rich plasma can promote the clinical healing of white-white meniscal tears.

    abstract：:The white-white tears (meniscus lesion completely in the avascular zone) are without blood supply and theoretically cannot heal. Basal research has demonstrated that menisci are unquestionably important in load bearing, load redistribution, shock absorption, joint lubrication and the stabilization of the knee joint. I...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/msm.883254

    authors： Wei LC,Gao SG,Xu M,Jiang W,Tian J,Lei GH

    更新日期：2012-08-01 00:00:00

  • Potential Role of Integrin α₅β₁/Focal Adhesion Kinase (FAK) and Actin Cytoskeleton in the Mechanotransduction and Response of Human Gingival Fibroblasts Cultured on a 3-Dimension Lactide-Co-Glycolide (3D PLGA) Scaffold.

    abstract：:BACKGROUND The stability of orthodontic treatment is thought to be significantly affected by the compression and retraction of gingival tissues, but the underlying molecular mechanism is not fully elucidated. The objectives of our study were to explore the effects of mechanical force on the ECM-integrin-cytoskeleton l...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/MSM.921626

    authors： Wei L,Chen Q,Zheng Y,Nan L,Liao N,Mo S

    更新日期：2020-02-08 00:00:00

  • Immediate speech fluency improvement after application of the Digital Speech Aid in stuttering patients.

    abstract：BACKGROUND:The Digital Speech Aid (DSA) is a pocket-sized device used for speech correction in stutterers. The device modifies the patient's auditory feedback with the use of Delayed Auditory Feedback (DAF) and Frequency-shifted Auditory Feedback (FAF). Both methods are well-known to improve speech fluency in stutterin...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/msm.882191

    authors： Ratyńska J,Szkiełkowska A,Markowska R,Kurkowski M,Mularzuk M,Skarżyński H

    更新日期：2012-01-01 00:00:00

  • Transforming growth factor-β1 rs1800470 polymorphism is associated with lung cancer risk: a meta-analysis.

    abstract：BACKGROUND:Transforming growth factor-β1 is a member of a large class of polypeptides that regulate the proliferation, differentiation, and carcinogenesis of epithelial cells. The rs1800470 polymorphism influences transforming growth factor-β1 expression and has been associated with lung cancer susceptibility. However,...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章,meta分析

    doi：10.12659/MSM.891122

    authors： Fan H,Yu H,Deng H,Chen X

    更新日期：2014-11-20 00:00:00

  • The role of Interleukin-17A and Interleukin-17E in multiple myeloma patients.

    abstract：BACKGROUND:Tumor growth in multiple myeloma (MM) is regulated by the cytokine networks which are produced by myeloma cells and the microenvironment of the bone marrow. Interleukin-17 (IL-17) is implicated in the increased angiogenesis in the bone marrow of MM. Recent studies reported elevated levels of interleukin 17A ...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/msm.882204

    authors： Lemancewicz D,Bolkun L,Jablonska E,Czeczuga-Semeniuk E,Kostur A,Kloczko J,Dzieciol J

    更新日期：2012-01-01 00:00:00

  • Skin rubdown with a dry towel activates natural killer cells in bedridden old patients.

    abstract：BACKGROUND:Skin rubdown using a dry towel to scrub the whole body is a traditional procedure. Because massage therapy is effective in improving cellular immunity, skin rubdown may also have the similar effects. MATERIAL/METHODS:Sixteen bedridden old patients, who had suffered a cerebral stroke, were studied. Skin rubd...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：

    authors： Iwama H,Akama Y

    更新日期：2002-09-01 00:00:00

  • Left Univentricular Pacing by Rate-Adaptive Atrioventricular Delay in Treatment of Chronic Heart Failure.

    abstract：:BACKGROUND Cardiac resynchronization therapy (CRT) is efficacious in the treatment of chronic heart failure (CHF); however, because it is non-physiological, some patients are unresponsive. The present study used rate-adaptive atrioventricular delay (RAAVD) to track the physiological atrioventricular delay and investig...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/msm.904348

    authors： Zhao L,Zhao L,Pu L,Hua B,Wang Y,Li S,Li Q,Guo T

    更新日期：2017-08-17 00:00:00

  • Outcomes of Laparoscopic Treatment in Women with Cesarean Scar Syndrome.

    abstract：:BACKGROUND The aim of this study was to evaluate the outcomes of laparoscopic treatment of women with severe defect of a Cesarean section (CS) scar and Cesarean scar syndrome. MATERIAL AND METHODS A prospective longitudinal study was conducted in 11 women who were treated for Cesarean scar syndrome. Ultrasound examina...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/msm.902720

    authors： Dosedla E,Calda P

    更新日期：2017-08-22 00:00:00

  • Circular RNA Myosin Light Chain Kinase (MYLK) Promotes Prostate Cancer Progression through Modulating Mir-29a Expression.

    abstract：:BACKGROUND In developed countries, prostate cancer (PCa) is a frequently diagnosed cancer with the second highest fatality rate. Circular RNAs (circRNAs) are a class of endogenous non-coding RNAs (ncRNAs) stably expressed in cells and involved in a series of carcinomas. However, few research studies have reported on t...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/MSM.908009

    authors： Dai Y,Li D,Chen X,Tan X,Gu J,Chen M,Zhang X

    更新日期：2018-05-25 00:00:00

  • The Role of Serine Peptidase Inhibitor Kazal Type 13 (SPINK13) as a Clinicopathological and Prognostic Biomarker in Patients with Clear Cell Renal Cell Carcinoma.

    abstract：:BACKGROUND The serine peptidase inhibitor Kazal type 13 (SPINK13) gene has tumor suppressor activity, but its role in renal cell carcinoma (RCC) remains unknown. This study aimed to investigate mRNA expression of SPINK13 in clear cell renal cell carcinoma (CCRCC) in human tissue and to use bioinformatics data to inves...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章

    doi：10.12659/MSM.917754

    authors： Xu WH,Shi SN,Wang J,Xu Y,Tian X,Wan FN,Cao DL,Qu YY,Zhang HL,Ye DW

    更新日期：2019-12-11 00:00:00

  • Womens heart health series: a mini-symposium.

    abstract：:Coronary artery disease is the leading cause of death for both men and women in the United States. While its incidence in men has been long appreciated, the impact on women has been underestimated for many years. This is in part because coronary artery disease generally appears later in women, the incidence increasing...

    journal_title：Medical science monitor : international medical journal of experimental and clinical research

    pub_type： 杂志文章,评审

    doi：

    authors： McLarty A,Mann N,Lawson WE,Foster A

    更新日期：2003-06-01 00:00:00