Abstract：
OBJECTIVE:congenital anosmia is extremely rare and tends to present late. We report on a series of patients with congenital anosmia to analyze its clinical characteristics and present illustrative cases. DESIGN:retrospective chart review. SETTINGS:tertiary care centre. METHODS:thirty-five patients with congenital anosmia were reviewed. A thorough medical history taking, physical examination, and nasal endoscopy were performed in all patients. T&T olfactory testing (n = 33), olfactory event-related potentials (OERPs) (n = 33), and sinonasal computed tomography (CT) (n = 35) were carried out. Magnetic resonance images (MRIs) of the olfactory pathway (n = 34) were available. Serum sex hormones were tested (n = 33). MAIN OUTCOME MEASURES:physical examination, olfactory testing, MRI of the olfactory pathway, and serum sex hormones. RESULTS:twenty cases were isolated congenital anosmia (ICA). Fifteen cases were congenital anosmia with other anomalies, including 12 cases with Kallmann syndrome (KS), two with CHARGE syndrome, and one with hypoplasia of the nasal cavity and nasal sinus. T&T olfactory testing indicated anosmia (n = 33). No OERP was obtained (n = 33). CT scans indicated three abnormal patients, including two with unilateral choanal atresia and one with hypoplasia of the nasal cavity and sinus. MRI demonstrated aplasia or hypoplasia of the olfactory bulbs, tracts, and olfactory sulci (n = 34). Serum sex hormones were low in 12 patients with KS. CONCLUSIONS:early diagnosis of congenital anosmia on the basis of olfactory symptoms is difficult. MRI of the olfactory pathway plays an important role in anatomic location. ICA is the most common congenital anosmia. KS is the primary presentation of congenital anosmia with other anomalies.
journal_name
J Otolaryngol Head Neck Surgjournal_title
Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-facialeauthors
Qu Q,Liu J,Ni D,Zhang Q,Yang D,Wang N,Wu X,Han Hsubject
Has Abstractpub_date
2010-12-01 00:00:00pages
723-31issue
6eissn
1916-0208issn
1916-0216journal_volume
39pub_type
杂志文章abstract：BACKGROUND:Operating room (OR) efficiency is related to minutes spared from surgical time and has been linked to the make up of surgical teams and operating room workplace. The research on the efficiency of surgical nursing staff members is scant. The current study evaluates the effect of ENT trained OR resource nurses...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-020-00431-8
更新日期：2020-07-23 00:00:00
abstract：INTRODUCTION:Adenoid cystic carcinoma (ACC) of the head and neck is a rare malignancy of salivary gland origin. Few epidemiologic studies exist assessing the incidence of this tumour. The purpose of the current study was to determine the incidence of ACC of the head and neck in Nova Scotia. Furthermore, we assessed sur...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND:Lip reconstruction for defects greater than 80 % present a challenge in maintaining acceptable oral function and good aesthetic results. Abbé flaps offer an excellent reconstructive option but are limited to defects under 65 %. METHODS:We describe a two-stage "modified Abbé island flap" technique whereby a ...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-016-0148-0
更新日期：2016-05-31 00:00:00
abstract：BACKGROUND:Despite significant anatomical variation amongst patients, cochlear implant frequency-mapping has traditionally followed a patient-independent approach. Basilar membrane (BM) length is required for patient-specific frequency-mapping, however cochlear duct length (CDL) measurements generally extend to the api...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-019-0398-8
更新日期：2020-01-06 00:00:00
abstract：BACKGROUND:Cocaine has traditionally been the topical decongestant most frequently used for visualization of the surgical field in Endoscopic Sinus Surgery (ESS). Alternatives include xylometazoline, oxymetazoline, and epinephrine. The understanding of the safety profile of each agent is changing, as are the practices ...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-019-0337-8
更新日期：2019-03-18 00:00:00
abstract：BACKGROUND:Tumours of the parotid gland are generally managed surgically without reconstruction. The usual long-term outcomes of these techniques are facial scars, asymmetry, and permanent contour deficits. These cosmetic deformities can significantly affect patients' self-image and negatively impact their quality of l...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:First branchial cleft anomalies are rare, accounting for only 10% of all branchial cleft anomalies. We report an even more rare and unique case of a branchial cleft cyst with features of both first and second arch derivatives. CASE PRESENTATION:A 6-year-old boy presented to us with a left conductive hearing...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-020-00426-5
更新日期：2020-05-29 00:00:00
abstract：BACKGROUND:Cochlear Duct Length (CDL) has been an important measure for the development and advancement of cochlear implants. Emerging literature has shown CDL can be used in preoperative settings to select the proper sized electrode and develop customized frequency maps. In order to improve post-operative outcomes, an...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章,评审
doi：10.1186/s40463-017-0194-2
更新日期：2017-03-07 00:00:00
abstract：OBJECTIVE:To assess the probability of nasopharyngeal carcinoma (NPC) being present among adults who appeared to suffer only from otitis media with effusion (OME). DESIGN AND SETTING:The clinical features of 87 adults suffering from OME but who demonstrated no other apparent symptoms and signs suggestive of NPC at the...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:Cisplatin-induced hearing loss is frequent and severe. Antioxidants such as sodium thiosulfate (STS) can neutralize the effects of cisplatin. The objective of the trial was to test the efficacy of trans-tympanic injections of a STS gel to prevent cisplatin-induced ototoxicity. METHODS:Eligible participants ...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章,随机对照试验
doi：10.1186/s40463-019-0327-x
更新日期：2019-01-16 00:00:00
abstract：OBJECTIVE:To evaluate the potential for hypothalamic-pituitary-adrenal (HPA) axis suppression by budesonide nasal irrigations in the treatment of refractory chronic rhinosinusitis with polyposis (CRSwP). STUDY DESIGN:Retrospective, descriptive review of patient charts. SETTING:Tertiary care rhinology practice in an a...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：
更新日期：2008-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the impact of socioeconomic status on the incidence of head and neck cancer using a population-based survey. METHODS:We employed pooled individual-level data from the US National Institutes of Health Survey for the years 1997 to 2006 inclusive. We performed a logistic regression analysis for four...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：
更新日期：2008-08-01 00:00:00
abstract：BACKGROUND:The American Thyroid Association published revised guidelines in 2015 on the management of differentiated thyroid cancer in adults. One of the key changes introduced in the revision proposes that diagnostic biopsy be based on ultrasound findings (i.e. size and nodule characteristics). The overall effect of t...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-018-0296-5
更新日期：2018-09-03 00:00:00
abstract：BACKGROUND:Sudden sensorineural hearing loss (SSHL) is a disease, which severely affects the patient's social and relational life. The underlying pathomechanisms have not been finally clarified yet and outcome is not predictable. METHODS:We conducted a retrospective study in order to identify parameters that influence...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-017-0207-1
更新日期：2017-04-04 00:00:00
abstract：BACKGROUND:Thyroid nodules are common but only a minority are malignant. Molecular testing can assist in helping determine whether indeterminate nodules are suspicious for malignancy or benign. The objective of the study was to determine if the analysis of mutations (BRAF, NRAS, KRAS and HRAS) using readily available m...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-015-0106-2
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:This prospective study investigated the change of swallowing ability using the Swallowing Ability Scale System (SASS) and swallowing-related quality of life (QOL) by Performance Status Scale for Head and Neck Cancer patients (PSS-H&N). This study also investigated the risk factors for postoperative dysphagia...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-020-00479-6
更新日期：2021-01-25 00:00:00
abstract：INTRODUCTION:Video teaching modules are proven effective tools for enhancing student competencies and technical skills in the operating room. Integration into post-graduate surgical curricula, however, continues to pose a challenge in modern surgical education. To date, video teaching modules for neck dissection have y...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/1916-0216-43-7
更新日期：2014-03-25 00:00:00
abstract：BACKGROUND:We have identified a cause of falsely elevated parathyroid hormone (PTH) levels after total parathyroidectomy with forearm auto-transplantation (TPT-ATx). Our cases highlight the need to draw PTH samples remotely, away from forearm graft sites, to ensure accurate levels. CASE PRESENTATIONS:We report on four...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-017-0226-y
更新日期：2017-06-23 00:00:00
abstract：OBJECTIVE:To assess wait times for surgery and radiotherapy in head and neck cancer patients from the Maritime provinces. METHODS:A retrospective chart review of 275 Maritime head and neck cancer patients treated between 2007 and 2009 by the tertiary Otolaryngology-Head and Neck Surgery Service at the Queen Elizabeth ...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND:The presence of a plane between the lingual tonsils and the underlying soft tissue has not been confirmed. The objective of this study is to ascertain the presence and the characteristics about this plane for surgical use. METHODS:Five cadaver heads were obtained for dissection of the lingual tonsils. Six p...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-016-0137-3
更新日期：2016-04-05 00:00:00
abstract：BACKGROUND:Oral cavity squamous cell carcinoma (OCSCC) is the most common head and neck cancer, affecting approximately 2000 Canadians yearly. Analysis of Canadian Cancer Registry data has shown that the incidence of oral cavity cancer is decreasing and survival outcomes are improving. There are significant health disp...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-015-0056-8
更新日期：2015-02-03 00:00:00
abstract：OBJECTIVE:To study the effects of various densities of middle ear fluids on acoustic immittance and elucidate the characteristics of this study that might be beneficial for clinical use in otitis media with effusion. STUDY DESIGN:Experimental, in vivo model. MATERIALS AND METHODS:The study was performed on 12 ears of...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：
更新日期：2008-02-01 00:00:00
abstract：BACKGROUND:The diagnosis of chronic rhinosinusitis (CRS) based on clinical presentation alone remains challenging. To improve the accuracy of clinical diagnosis, the Canadian Rhinosinusitis Guidelines recommend the use of specific symptom and endoscopic criteria. Our study objective was to determine whether symptom and...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-017-0243-x
更新日期：2017-12-04 00:00:00
abstract：BACKGROUND:Human papillomavirus (HPV) has recently been implicated as a causative agent in a rapidly growing number of oropharyngeal cancers. Emerging literature supports the hypothesis that HPV vaccination may protect against HPV-related head and neck cancer (HNC) in addition to HPV-related cervical and anogenital dis...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-017-0237-8
更新日期：2017-10-26 00:00:00
abstract：OBJECTIVE:To compare minimally invasive parathyroidectomy (MIP) under local anesthesia (MIPULA) to minimally invasive parathyroidectomy performed under general anesthesia (MIPUGA) in terms of postoperative pain, postanesthetic side effects, patient satisfaction, and overall outcome. DESIGN:Prospective comparative coho...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVE:To investigate effects of recreational noise exposure on olivocochlear efferent function. METHODS:efferent suppression of DPOAEs and acoustic reflexes were tested in 32 young personal listening device users with normal hearing and compared with that of healthy, non-noise-exposed young adults. RESULTS:The re...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：
更新日期：2010-08-01 00:00:00
abstract：:Following publication of the original article [1], the authors reported an error in one of the author names. In this Correction the incorrect and correct author names are listed. ...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章,已发布勘误
doi：10.1186/s40463-018-0294-7
更新日期：2018-08-02 00:00:00
abstract：INTRODUCTION:The purely endoscopic approach to sellar tumors is thought to offer improved visualization and decreased complications compared to the endoscopic assisted approach. METHODS:This retrospective study was approved by the Research Ethics Board (REB) of McMaster University. Seventy-one consecutive patients who...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:Benign vocal fold lesions identified in professional voice users, frequently require further treatment after failure of conservative measures. The role of vocal fold steroid injection as a treatment option for select benign lesions is the focus of this study. Steroid injection may avoid phonosurgery in some ...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：10.1186/s40463-020-00434-5
更新日期：2020-07-20 00:00:00
abstract：OBJECTIVE:The aim of the present study was to investigate cerebral hemodynamics in patients with sleep-disordered breathing of variable severity using cerebral near-infrared spectroscopy. DESIGN:Prospective study. SETTING:Tertiary training and research hospital. METHODS:The study was performed in patients referred f...
journal_title：Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
pub_type： 杂志文章
doi：
更新日期：2012-12-01 00:00:00
