Abstract:
:This research aimed to prepare 166Dy₂O₃-iPSMA/166Ho₂O₃-iPSMA nanoparticles (166Dy₂O₃/166Ho₂O₃-iPSMA NPs) and assess the radiation absorbed dose produced by the nanosystem to hepatic cancer cells by using experimental in vitro and in vivo biokinetic data. Dy₂O₃NPs were synthesized and functionalized with the prostate-specific membrane antigen inhibitor peptide (iPSMA). Fourier transform infrared (FTIR) spectroscopy, transmission electron microscope (TEM), dynamic light scattering (DSL) and zeta potential analyses indicated the formation of Dy₂O₃-iPSMA NPs (46.11 ± 13.24 nm). After neutron activation, a stable 166Dy₂O₃/166Ho₂O₃- iPSMA nanosystem was obtained, which showed adequate affinity to the PSMA receptor in HepG2 cancer cells (K d = 9.87 ± 2.27 nM). in vitro studies indicated high 166Dy₂O₃/166Ho₂O₃-iPSMA internalization in cancer cells, with high radiation doses to cell nuclei (107 Gy) and cytotoxic effects, resulting in a significant reduction in HepG2 cell viability (decreasing to 2.12 ± 0.31%). After intratumoral administration in mice, the nanosystem biokinetic profile indicated significant retention into the tumoral mass, producing ablative radiation doses (>70 Gy).
journal_name
J Nanosci Nanotechnoljournal_title
Journal of nanoscience and nanotechnologyauthors
Canseco-Hernández O,Ferro-Flores G,Jimenez-Mancilla N,Aranda-Lara L,Ocampo-Garcia B,Trujillo-Benitez D,Ancira-Cortés A,Morales-Avila E,Santos-Cuevas Cdoi
10.1166/jnn.2021.19455subject
Has Abstractpub_date
2021-11-01 00:00:00pages
5449-5458issue
11eissn
1533-4880issn
1533-4899journal_volume
21pub_type
杂志文章abstract::Transition metal and nitrogen co-doped carbon-based catalysts (TM-N-C) have become the most promising catalysts for Pt/C due to their wide range of sources, low cost, high catalytic activity, excellent stability and strong resistance to poisoning, especially Fe-N-C metal-organic frameworks (MOFs), which are some of th...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19310
更新日期:2021-10-01 00:00:00
abstract::Carbon steel (CS) is the preferred base material for construction in various industries due to its low cost; however, industrial equipment failure caused by carbon steel corrosion can lead to several environmental risks and safety hazards, thus limiting its application scenarios. Enhancing the corrosion resistance of ...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19371
更新日期:2021-10-01 00:00:00
abstract::Herein, we report a surface modified TiO₂ nanowire arrays (NAs) photoanode based photocatalytic fuel cell (PFC) towards simultaneous enhancement of actual wastewater treatment and electricity generation under visible light irradiation. TiO₂ NAs were facile fabricated via two-step anodization process in ethylene glycol...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19442
更新日期:2021-10-01 00:00:00
abstract::The present study aims to prepare and And Characterization of zein nanofibers with simvastatin-loaded in it by electrospinning method using a polymeric matrix prepared from zein solution containing simvastatin antibiotics. The physical, cellular properties and drug release kinetics of the fibers were studied. Fiber fo...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19367
更新日期:2021-10-01 00:00:00
abstract::Nanofabrication of functional micro/nano-features is becoming increasingly relevant in various electronic, photonic, energy, and biological devices globally. The development of these devices with special characteristics originates from the integration of low-cost and high-quality micro/nano-features into 3D-designs. G...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19327
更新日期:2021-10-01 00:00:00
abstract::Two reactive energetic plasticizers, 3-((2,2-dinitropropoxy)methoxy)prop-1-yne and 4-((2,2-dinitropropoxy)methoxy)but-1-yne which can react with an azido-containing poly(glycidyl azide-co-tetramethylene glycol) prepolymer by cupper-free 1,3-dipolor cycloaddition ("Click") reaction, were synthesized and characterized, ...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19184
更新日期:2021-07-01 00:00:00
abstract::The complete oxidation of toluene (as a model volatile organic compound) was studied to determine the influence of adding a transition metal (Mn, Cr, Fe, Co, and Ni) to the 5 Cu/Al catalyst. The physcochemical properties of the catalysts were characterized by Brunauer-Emmett-Teller (BET) surface area analysis, X-ray d...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19177
更新日期:2021-07-01 00:00:00
abstract::A dense nanostructured 2HfB₂-SiC composite was simultaneously synthesized and consolidated by the pulsed current activated sintering method in one step within very short time (two minutes) from mechanically activated 2Hf, B₄C and Si powders. Simultaneous combustion synthesis and consolidation were achieved through the...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19243
更新日期:2021-07-01 00:00:00
abstract::Two immobilization methods (i.e., ice water-soaked using a digital temperature controller vs. freeze-dried using liquid nitrogen) were applied for mass production techniques of TiO₂-embedded expanded polystyrene (TiEPS) balls with nanoscale TiO₂ particles embedded on EPS balls. No significant changes in crystalline st...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19180
更新日期:2021-07-01 00:00:00
abstract::A simple light extraction method is reported to minimize the variation in emission spectrum with viewing angle by embedding a light extraction layer, consists of randomly dispersed nano-pillars on a substrate. Nano-imprint lithography technique was employed to fabricate the nano-pillars using ultra-violet curable acry...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19229
更新日期:2021-07-01 00:00:00
abstract::The effects of discharge conditions and catalysts on CO₂ methanation under the plasma were investigated via In-Situ transmission FTIR and OES analysis. The bare Al₂O₃, Ni/Al₂O₃ and Ru/Al₂O₃ catalysts were coated on the ZnSe window using the modified sol-gel method for In-Situ transmission FTIR analysis. It was confirm...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19187
更新日期:2021-07-01 00:00:00
abstract::In this investigation we report the formation of thin ZnO recombination barrier layer at TiO₂/CdS interface aimed for the improvement in performance of CdS sensitized solar cell. The film was deposited upon nanocrystalline mesoporous TiO₂ surface by following a simple chemical process and characterized, using UV-Visib...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19234
更新日期:2021-07-01 00:00:00
abstract::In this paper, we reported superior performance of solution-processed top-emission quantum dot light-emitting diodes (TE-QLEDs) with Mg-doped ZnO nanoparticle (NP) electron transport layer (ETL). The Mg-doped ZnO NPs were synthesized by the sol-gel method. Transmission electron microscopy (TEM) analysis of the Mg-dope...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19230
更新日期:2021-07-01 00:00:00
abstract::CDs are carbon fluorescent nanomaterials that have gained significant attention in recent years owing to their unique properties. In this work, we utilized a simple solution to produce CDs with func-tionalized amino groups via a one-step carbonization from a chitosan precursor. This simultaneous approach does not use ...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19178
更新日期:2021-07-01 00:00:00
abstract::CuO nanoparticles (NPs) have been used for the antimicrobial agent against different pathogenic microorganisms. In this study, CuO NPs are immobilized on the surface of activated carbon fiber (ACF) with the enhancement of (3-aminopropyl)triethoxysilane (APTES) as an organic binder. The obtained fibers are evaluated by...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19428
更新日期:2021-08-01 00:00:00
abstract::In this study, we investigated thermoelectric materials with durability against mechanical stress using Ag₂Se nanoparticle (NP) thin films and colorless polyimide (CPI) substrates. Ag₂Se NP thin films and CPI substrates were produced by spin-coating, and their thicknesses were 40 nm and 15 μm, respectively. A bendable...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19429
更新日期:2021-08-01 00:00:00
abstract::In this study, we examined the highly selective sensing of Fe3+ ions in water using metal complex-functionalized mesoporous silica materials. Metal complex-functionalized mesoporous silica materials were synthesized on the mesoporous surface of SBA-15 via complexation process between Eu3+ and aminosilane groups. Mesop...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19425
更新日期:2021-08-01 00:00:00
abstract::Highly efficient blue fluorescent 7,7-dimethyl-9-(10-phenylanthracen-9-yl)-7H-benzo[6,7]indeno[1,2- f]quinoline derivatives, based on benzo-indeno-quinoline and phenylanthracene were designed and synthesized. To test their electroluminescent properties, organic light-emitting diodes (OLEDs) were fabricated with the co...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19400
更新日期:2021-08-01 00:00:00
abstract::The switching characteristics of a vanadium dioxide (VO₂) thin-film device, in which the current flowing through the device can be switched through the photothermal effect using focused laser pulses, were investigated according to the dimensions of the sapphire substrate on which the VO₂ thin film was deposited throug...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19402
更新日期:2021-08-01 00:00:00
abstract::In this study, we report the self-nanostructured growth of 4,6-bis(3,5-di(pyridin-3-yl)phenyl)-2-methylpyrimidine (B3PyMPM), which is widely used as an electron transport layer for organic light-emitting diodes (OLEDs). B3PyMPM nanostructures were formed on the surface of a substrate using vacuum thermal evaporation, ...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19385
更新日期:2021-08-01 00:00:00
abstract::Zirconia ceramics has a bioinert property with low bioactivity. So, it is necessary to improve its low bioactivity by the surface modification using effective coating methods. In this study, we fabricated the hydroxyapatite-coated zirconia substrate by room temperature spray processing to improve the bioactivity of th...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19373
更新日期:2021-08-01 00:00:00
abstract::In the present study, a YBa₂Cu₃O7-y bulk superconductor added with 5~10 wt% Ag was fabricated employing Sm123 as a seed to produce a superconductive single crystal. Metallic silver was added to the single crystal of YBa₂Cu₃O7-y to remove defects such as cracks and pores. Electromagnetic properties of the bulk supercon...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19274
更新日期:2021-09-01 00:00:00
abstract::This study demonstrates a method to improve the surface quality by adding artificial vibration to the electrolyte in electrochemical polishing (ECP, electropolishing). ECP is a typical non-contact surface polishing process that has been used to improve surface quality without leaving any of the mechanical scratch mark...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19264
更新日期:2021-09-01 00:00:00
abstract::The new wood-plastic nanocomposites (WPC) based on acrylonitrile-butadiene-styrene (ABS) resin was successfully blended with ABS and poplar flour (PF) through a HAAKE rheomix. The mechanical properties of nanocomposites, except for flexural modulus, were reduced after increasing the PF content. SEM photos show the red...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19326
更新日期:2021-09-01 00:00:00
abstract::A cold roll-bonding process was applied to fabricate an AA1050/AA6061/AA5052/AA1050 four-layer clad sheet and subsequently annealed. Three types of aluminum alloy sheets such as AA1050, AA6061 and AA5052 with 2 mm thickness, 40 mm width and 300 mm length were stacked up each other after such surface treatment as degre...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19267
更新日期:2021-09-01 00:00:00
abstract::Multi-structured platinum nanoclusters have been prepared through a one-step aqueous synthetic process by controlling pHs. The included structures are closely packed 3-dimensional (3D) dendrites, loosely packed 3D dendrites, short-order dendritic chains, long-order dendritic chains, flatten nanoclusters and monodisper...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19287
更新日期:2021-09-01 00:00:00
abstract::This study prepared silicone hydrogel ophthalmic lenses using 2-hydroxyethylmethacrylate (HEMA), synthesized silicone monomer (SID), dimethylarsinic acid (DMA), N-hydroxyethyl acrylamide (HEA), ethylene glycol dimethacrylate (a crosslinking agent, EGDMA), and azobisisobutyronitrile (an initiator, AIBN). Also, Zirconiu...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19291
更新日期:2021-09-01 00:00:00
abstract::In this investigation, a sensitive sensor for ochratoxin A detection was designed based on graphene oxide (GO) and DNase I for amplified fluorescence signal. The outcomes of this investigation indicated that this exploratory platform exhibited efficient sensitivity and good selectivity for ochratoxin A when existence ...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19348
更新日期:2021-09-01 00:00:00
abstract::Norfloxacin (NF) is an emerging antibiotic contaminant due to its significant accumulation in the environment. Photocatalytic degradation is an effective method for removing emerging contaminant compounds in aqueous solution; however, it is not commonly applied because of the poor solubility of contaminant compounds i...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19150
更新日期:2021-05-01 00:00:00
abstract::Hierarchical nanoparticles are of great interest because they possess unique physicochemical properties and multiple functionalities, providing a wealth of possibilities for various applications. In this work, we have developed a well-designed method to prepare hierarchical magnetic nanoparticles Fe₃O₄@mSiO₂@CS by int...
journal_title:Journal of nanoscience and nanotechnology
pub_type: 杂志文章
doi:10.1166/jnn.2021.19154
更新日期:2021-05-01 00:00:00