Abstract:
BACKGROUND:The clinico-surgical implication and successful management of a rare case of factor five (V) deficiency with portal hypertension and hypersplenism due to idiopathic extra-hepatic portal venous obstruction is presented. CASE PRESENTATION:A 16-year old boy had gastro-esophageal variceal bleeding, splenomegaly and hypersplenism. During preoperative workup prolonged prothrombin time and activated partial thromboplastin time were detected, which on further evaluation turned out to be due to factor V deficiency. Proximal lieno-renal shunt and splenectomy were successfully performed with transfusion of fresh frozen plasma during and after the surgical procedure. At surgery there was no excessive bleeding. The perioperative course was uneventful and the patient is doing well on follow up. CONCLUSION:Surgical portal decompressive procedures can be safely undertaken in clotting factor deficient patients with portal hypertension if meticulous surgical hemostasis is achieved at operation and the deficient factor is adequately replaced in the perioperative period.
journal_name
BMC Surgjournal_title
BMC surgeryauthors
Chava SP,Pal S,Ghatak S,Kumar R,Sahni P,Chattopadhyay TKdoi
10.1186/1471-2482-6-7subject
Has Abstractpub_date
2006-05-19 00:00:00pages
7issn
1471-2482pii
1471-2482-6-7journal_volume
6pub_type
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