CD44-targeted pH-responsive micelles for enhanced cellular internalization and intracellular on-demand release of doxorubicin.

abstract：:A composite electrode was prepared by modifying glassy carbon micro particles with gold nanoparticles and glucose oxidase enzyme for glucose detection. In terms of analytical characteristics, a linearity was obtained in the concentration range between 50.0 and 1000.0 µM with equation of y = 0.0015x + 0.2336 with the c...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Anik U,Cubukçu M,Yavuz Y

更新日期：2013-02-01 00:00:00

abstract：:In this study a novel composite cryogel column was synthesized for affinity depletion of immunoglobulin G (IgG) from human serum. The microsphere-embedding technique combines the large surface area of microspheres with excellent properties of cryogels. The poly(hydroxyethyl methacrylate- N-methacryloyl-L-histidine met...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Baydemir G,Odabaşı M

更新日期：2013-10-01 00:00:00

abstract：:Cellulose powder was oxidized by NO2 gas and the porous scaffold was fabricated by dry pressing. RGD peptide was immobilized on the surface of scaffold by grafting to make a hybrid scaffold. The hybrid scaffold was characterized by SEM and FTIR and its biocompatibility was examined through MTT assay. FTIR results prov...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Mahmoodi M,Hossainalipour SM,Naimi-Jamal MR,Samani S,Samadikuchaksaraei A,Rezaie HR

更新日期：2013-12-01 00:00:00

abstract：:The pure motor peripheral nerves animal model, obtained by ablating the dorsal root ganglions (DRGs), was used to investigate the accuracy of peripheral nerve selective regeneration using small gap sleeve bridging compared to epineurium neurorrhaphy. The results showed that the number of improperly regenerated motor a...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Kou Y,Peng J,Wu Z,Yin X,Zhang P,Zhang Y,Weng X,Qiu G,Jiang B

更新日期：2013-12-01 00:00:00

abstract：:HEMA-Lactate-Dextran cryogel scaffolds were produced by cryogelation. Mesencyhmal stem cells (MSC) were isolated from rat bone marrow. Critical sized cranial bone defects were created in rat cranium. Stem cells were injected inside the macropores of the cryogel scaffolds prepared from HEMA-Lactate-Dextran possessing t...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Bölgen N,Korkusuz P,Vargel İ,Kılıç E,Güzel E,Çavuşoğlu T,Uçkan D,Pişkin E

更新日期：2014-02-01 00:00:00

abstract：:The success of cell microencapsulation technology in tissue engineering and protein delivery applications depends on the viability and functionality of the encapsulated cells, which in turn are dependent upon cell/matrix interactions. In this work, we compared the viability of cord blood-derived mesenchymal stromal ce...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Sayyar B,Dodd M,Marquez-Curtis L,Janowska-Wieczorek A,Hortelano G

更新日期：2014-04-01 00:00:00

abstract：:The objective of this study is to investigate the effects of BML-111 on acute pancreatitis-associated lung injury (APALI) induced by cerulein with subsequent an LPS administration in mice and its possible mechanisms. One hundred and twenty-eight mice were randomly allocated to four groups, namely the APALI group, the ...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Wang YZ,Zhang YC,Cheng JS,Ni Q,Li PJ,Wang SW,Han W,Zhang YL

更新日期：2014-04-01 00:00:00

abstract：:In this study, a novel amperometric glucose biosensor with immobilization of glucose oxidase on electrochemically polymerized polyaniline-polyvinylsulphonate-potassium ferricyanide (Pani-Pvs-Fc) films has been accomplished via the entrapment technique. Potassium ferricyanide was used as the mediator. Determination of ...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Arslan F,Beskan U

更新日期：2014-08-01 00:00:00

abstract：:Controlled drug delivery system is a technique which has considerable recent potential in the fields of pharmacy and medicine. Mitomycin C is commonly used drug in the treatment of superficial bladder and breast cancers. In the present study, mitomycin C-imprinted magnetic poly(hydroxyethyl methacrylate)-based nanopar...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Türkmen D,Bereli N,Çorman ME,Shaikh H,Akgöl S,Denizli A

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:By in situ polymerization of poly-L-lactic acid (PLLA) and nano-hydroxyapatite (Nano-HA), and finding the best proportion of composite, so as to get ideal interface fixation material. METHODS:According to a certain ratio (the mass fraction of Nano-HA, respectively, is 0%, 10%, 20%, 30% and 40%), composite PL...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Zhu W,Huang J,Lu W,Sun Q,Peng L,Fen W,Li H,Ou Y,Liu H,Wang D,Zeng Y

更新日期：2014-10-01 00:00:00

abstract：:The selective binding of albumin on dye-affinity nanospheres was combined with magnetic properties as an alternative approach for albumin depletion from human plasma. Magnetic poly(hydroxyethyl methacrylate) (mPHEMA) nanospheres were synthesized using mini-emulsion polymerization method in the presence of magnetite po...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Gökay Ö,Karakoç V,Andaç M,Türkmen D,Denizli A

更新日期：2015-02-01 00:00:00

abstract：:A new approach to albumin removal for proteome studies involving human plasma samples was presented with dye affinity poly glycidyl methacrylate (PGMA) nanobeads in an average size of 45 nm. The specific surface area of PGMA nanobeads was calculated as 2616 m(2)/g. Cibacron Blue F3GA (CB) was immobilized onto PGMA nan...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Andaç M

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To study the clinical effect of bone defect treated with nano-hydroxyapatite(Nano-HA) artificial bone. METHODS:From September 2009 to June 2012, 27 cases of bone defect were analyzed retrospectively. The position of bone defect included humerus, radius, ulna, femur, tibia and calcaneus. The range of bone def...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Zhu W,Wang D,Xiong J,Liu J,You W,Huang J,Duan L,Chen J,Zeng Y

更新日期：2015-01-01 00:00:00

abstract：:Microscopic, fiber-shaped cell aggregates, have been used as building blocks for fabricating macroscopic three-dimensional tissue architectures, in the field of tissue engineering. In this study, we examined the occurrence of necrotic regions in the most widely used, fiber-shaped cell aggregates, approximately 100 μm ...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Takei T,Kitazono J,Tanaka S,Nishimata H,Yoshida M

更新日期：2016-01-01 00:00:00

abstract：:A novel biosensor for determination of L-glutamine in pharmaceutical glutamine powder was developed via immobilizing our produced glutaminase enzyme from Hypocria jecorina onto our prepared zinc oxide (ZnO) nanorod and chitosan. ZnO nanorods were prepared as surface-dependent and surface-independent and both were used...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Albayrak D,Karakuş E

更新日期：2016-01-01 00:00:00

abstract：:Present invention relates to design of nanostructured lipid carriers (NLC) to augment oral bioavailability of Carvedilol (CAR). In this attempt, formulations of CAR-NLCs were prepared with glyceryl-monostearate (GMS) as a lipid, poloxamer 188 as a surfactant and tween 80 as a co-surfactant using high pressure homogeni...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Patil GB,Patil ND,Deshmukh PK,Patil PO,Bari SB

更新日期：2016-01-01 00:00:00

abstract：:Cardiovascular disease is the disease that affects the cardiovascular system, vascular diseases of the brain and kidney, and peripheral arterial disease. Despite of all advances in pharmacological and clinical treatment, heart failure is a leading cause of morbidness and mortality worldwide. Many new therapeutic advan...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Singh B,Garg T,Goyal AK,Rath G

更新日期：2016-01-01 00:00:00

abstract：:The objectives were to study the potential of Pulicaria gnaphalodes (Vent.) Boiss. aerial parts in production of nanoparticles and the effect of the extraction solvent on the produced nanoparticles. Methanol and dichloromethane extracts were prepared by percolation of the plant powder. Both the extracts of P. gnaphalo...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Chitsazi MR,Korbekandi H,Asghari G,Bahri Najafi R,Badii A,Iravani S

更新日期：2016-01-01 00:00:00

abstract：:The construction of an L-lysine biosensor on ammonium-selective poly(vinylchloride) (PVC) membrane electrode is described in this study. The construction procedure occurs in two stages: (I) the preparation of ammonium-selective poly(vinylchloride) (PVC) membrane electrode and (II) the chemical immobilization of lysine...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Yarar S,Karakuş E

更新日期：2016-01-01 00:00:00

abstract：:Polyethyleneimine (PEI) coated-silica nanoparticles were prepared by the Stöber method. The formation and the structure of the nanoparticles were characterized by ATR-FT-IR spectroscopy and transmission electron microscopy (TEM). TEM images of the silica and PEI-coated nanoparticles revealed that they were well disper...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Tumturk H,Yüksekdag H

更新日期：2016-01-01 00:00:00

abstract：:The basic objective of this study was to prepare quercetin-loaded liposomes by the thin film hydration method. The liposomal formulation was optimized using response surface methodology (RSM). A rotation speed of 75 rpm and a water bath temperature of 46°C were finalized as the best for optimized drug-loaded liposomal...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Jangde R,Singh D

更新日期：2016-01-01 00:00:00

abstract：:The blending of polymers is of great interest, since the modification gives rise to diverse physical properties with the functionality of a polymer, without synthesis. Water-soluble antitumor-active poly(maleic anhydride-alt-acrylic acid) poly(MA-alt-AA) and poly(ethylene glycol) (PEG) blends were prepared by casting,...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Can HK,Parvizikhosroshahi S,Uluışık EC

更新日期：2016-01-01 00:00:00

abstract：:Induced pluripotent stem (iPS) cells are generated from differentiated adult somatic cells by reprogramming them. Unlimited self-renewal, and the potential to differentiate into any cell type, make iPS cells very promising candidates for basic and clinical research. Furthermore, iPS cells can be genetically manipulate...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Zare M,Soleimani M,Mohammadian M,Akbarzadeh A,Havasi P,Zarghami N

更新日期：2016-01-01 00:00:00

abstract：:The aim of the current investigation is to evaluate the potential of capsaicin (CAP)-containing liposomes, niosomes and emulsomes in providing localized and controlled delivery, to improve the topical delivery of drug. CAP-bearing systems were prepared by the film hydration method and compared through various in vitro...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Gupta R,Gupta M,Mangal S,Agrawal U,Vyas SP

更新日期：2016-05-01 00:00:00

abstract：:This paper aims to provide an effective, accurate, and specific diagnostic method for the diagnosis of pancreatic cancer. It discusses the diagnostic value of magnetic res retrograde cholangiopancreatography (MRCP) combined with the detection of tumor marker carbohydrate antigen 19-9 (CA19-9) for pancreatic cancer. A ...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Ma S,Duan J,Li W,Zhang H,Hou Z

更新日期：2016-01-01 00:00:00

abstract：:The new research tried to improve the distribution of molecular weight of Hb-based oxygen carriers (HBOC), a bottleneck of glutaraldehyde (GDA)-polymerization process. The orthogonal experiments were done on the basis of the early study of human placenta Hemoglobin (Hb)-crosslinked-GDA and three factors were selected ...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Zhou W,Li S,Hao S,Liu J,Wang H,Yang C

更新日期：2015-06-01 00:00:00

abstract：:Magnetic iron oxide nanoparticles (IONPs) were coated with gelatin type B by means of the two-step desolvation method. Drug loading by adsorption was studied under various conditions such as different temperature, contact time, pH, and initial gemcitabine concentration. Further, Langmuir isotherm curves were constract...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Hamarat Sanlıer S,Yasa M,Cihnioglu AO,Abdulhayoglu M,Yılmaz H,Ak G

更新日期：2016-05-01 00:00:00

abstract：:The extracellular environment is a complex network of functional and structural components that impart chemical and mechanical stimuli that affect cellular function and fate. Cell differentiation on three dimensional scaffolds is also determined by the modulus of the substrate. Electrospun PCL nanofibers, which mimic ...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Elamparithi A,Punnoose AM,Kuruvilla S,Ravi M,Rao S,Paul SF

更新日期：2016-05-01 00:00:00

abstract：:A biosensor was developed using glutathione peroxidase (GSH-Px) as the enzyme. Firstly, platinum (Pt) nanoparticles were deposited onto a glassy carbon paste electrode (GCPE), and then GSH-Px was immobilized by means of gelatin that was then crosslinked with glutaraldehyde. The measurement was based on the electrochem...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Anik Ü,Çubukçu M,Ertaş FN

更新日期：2016-05-01 00:00:00

abstract：:The method based on integrating the principles of solid dispersion and nanocrystal techniques was developed to prepare polymer crystals (PCs) of mebendazole (MBZ) and polyethylene glycol (PEG). Powder X-Ray diffraction (PXRD) of the PC crystals shows the required integrated crystalline and amorphous regions. The in vi...

journal_title：Artificial cells, nanomedicine, and biotechnology

authors： Chaudhary S,Garg T,Rath G,Murthy RR,Goyal AK

更新日期：2016-05-01 00:00:00