Abstract：
:Levodopa (biological precursor of dopamine) is sometimes used instead of dopamine for synthesis of highly adhesive polycatecholamine coatings on different materials. However, in comparison of polydopamine, little is known about biological safety of poly(levodopa) coatings and their efficacy in binding of therapeutically active substances. Therefore, thermally polymerized curdlan hydrogel was modified via two different modes using levodopa instead of commonly used dopamine and then coupled with gentamicin - aminoglycoside antibiotic. Physicochemical properties, biological safety and antibacterial potential of the hydrogels were evaluated. Poly(levodopa) deposited on curdlan exhibited high stability in wide pH range and blood or plasma, were nontoxic in zebrafish model and favored blood clot formation. Simultaneously, one of hydrogel modification modes allowed to observe high gentamicin binding capacity, antibacterial activity, relatively high nontoxicity for fibroblasts and was unfavorable for fibroblasts adhesion. Such modified poly(levodopa)-modified curdlan showed therefore high potential as wound dressing biomaterial.
journal_name
Carbohydr Polymjournal_title
Carbohydrate polymersauthors
Michalicha A,Roguska A,Przekora A,Budzyńska B,Belcarz Adoi
10.1016/j.carbpol.2021.118485keywords:
["Antibacterial activity","Danio rerio","Fibroblasts","Poly(levodopa)-based modification","β-Glucan"]subject
Has Abstractpub_date
2021-11-15 00:00:00pages
118485eissn
0144-8617issn
1879-1344pii
S0144-8617(21)00872-9journal_volume
272pub_type
杂志文章abstract：:Hydrogels have been widely used for various applications, and thus addressing the challenges associated with the design of sustainable hydrogels has become an important issue. However, little attention has been devoted toward the design of crosslinkers which are often toxic, lack self-healing capabilities, and derived...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117978
更新日期：2021-07-15 00:00:00
abstract：:Hydrogels are an attractive system for a myriad of applications. While most hydrogels are usually formed from synthetic materials, lignocellulosic biomass appears as a sustainable alternative for hydrogel development. The valorization of biomass, especially the non-woody biomass to meet the growing demand of the subst...
journal_title：Carbohydrate polymers
pub_type： 杂志文章,评审
doi：10.1016/j.carbpol.2021.118036
更新日期：2021-07-15 00:00:00
abstract：:The safe and effective drug delivery system is important for cancer therapy. Here in, we first constructed a delivery system Cabazitaxel(Cab)@MPN/CS between metal-polyphenol (MPN) and chitosan (CS) to deliver Cab for melanoma therapy. The preparation process is simple, green, and controllable. After introducing CS coa...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.118000
更新日期：2021-07-15 00:00:00
abstract：:This study focuses on the production and characterization of electrosprayed cashew gum (CG) microparticles that encapsulate β-carotene. CG is an inexpensive, non-toxic polysaccharide obtained from Anacardium occidentale trees. Encapsulation of β-carotene in CG was performed by electrospraying from two emulsion formula...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.118060
更新日期：2021-07-15 00:00:00
abstract：:Green seaweeds of the genus Ulva are rich in the bioactive sulfated polysaccharide ulvan. Herein we characterise ulvan from Ulva species collected from the Bay of Plenty, Aotearoa New Zealand. Using standardised procedures, we quantified, characterised, and compared ulvans from blade (U. australis, U. rigida, U. sp. B...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.118010
更新日期：2021-07-15 00:00:00
abstract：:To develop a biomaterial to lift the lesion and promote wound healing in endoscopic submucosal dissection (ESD), we used lactobionic acid (LA) to improve the water solubility of chitosan (CS) and prepared a new three-phase hydrogel system with lactobionic acid-modified chitosan/chitosan/β-glycerophosphate (CSLA/CS/GP)...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.118001
更新日期：2021-07-01 00:00:00
abstract：:We prepared a self-dispersed cellulose-based microgel via chemically bonding hydrophilic gelatin peptide chain onto cellulose glucose chain. Following, a variety of highly transparent, foldable, and writable photoluminescent polymer films was obtained through loading organic dyes and inorganic pigments onto cellulose-...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117977
更新日期：2021-07-01 00:00:00
abstract：:The molecular structure of sulfonated chitosan is similar to heparin, and it has been proved to have some heparin functions. Studies have shown that heparin and bone morphogenetic protein-2 (BMP-2) have synergistic effects, but heparin has limitations in clinical application. In this paper, the synergistic effect of 2...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117888
更新日期：2021-07-01 00:00:00
abstract：:A fucosylated chondroitin sulfate was isolated from the body wall of sea cucumber Stichopus japonicus (FCSsj), whose structure was characterized by NMR spectroscopy and HILIC-FTMS. At the ratio of 1.00:0.26:0.65, three fucosyl residues were found: 2,4-disulfated-fucose (Fuc2,4S), 4-sulfated-fucose (Fuc4S) and 3,4-disu...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117969
更新日期：2021-06-15 00:00:00
abstract：:The linear anionic polysaccharide alginate (ALG) has been comprehensively studied for biomedical applications, yet thus far the in vivo fate of this polymer has not been explored in detail. The current study therefore evaluates the biodistribution of ultrapure ALG (M/G ratio ≥ 0.67 with a measured Mw of 530 kg/mol and...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117947
更新日期：2021-06-15 00:00:00
abstract：:Antibacterial property for scaffolds is an urgent problem to prevent infections in bone repair. Ag nanoparticles possess excellent bactericidal activities, whereas their agglomeration restricts the full play of antibacterial property in scaffold. Herein, a mace-like nanosystem was constructed to improve their dispersi...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117937
更新日期：2021-06-15 00:00:00
abstract：:Two pectic polysaccharides (WRSP-A2b and WRSP-A3a) have been obtained from Radix Sophorae Tonkinensis and comparatively investigated in terms of their physical properties and antioxidant activities. Monosaccharide composition, FT-IR, NMR and enzymatic analyses indicate that both WRSP-A2b (13.6 kDa) and WRSP-A3a (44.6 ...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117925
更新日期：2021-06-15 00:00:00
abstract：:Silver nanoparticle (AgNP) incorporated chitosan-Polyvinyl alcohol (Ch/PVA) hydrogel nanocomposite was fabricated by repeated freeze-thaw treatment using glutaraldehyde as crosslinker for removal of herbicide butachlor from aqueous solution. Ch/PVA hydrogel provided a matrix for in-situ immobilization of AgNPs and wer...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117906
更新日期：2021-06-15 00:00:00
abstract：:In this study, copper oxide nanoparticles, prepared using pistacia vera hull extract, were immobilized onto chitosan. FT-IR spectrum of copper oxide-chitosan exhibited chemical shifting of the main peaks of the biopolymer indicating that hydroxyl and amino groups were reacted with copper oxide nanoparticles. SEM featu...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117908
更新日期：2021-06-01 00:00:00
abstract：:Liver glycogen is a branched glucose polymer that functions as a blood-sugar buffer in animals. Previous studies have shown that glycogen's molecular structure affects its properties. This makes it important to develop a technique that extracts and purifies a representative sample of glycogen. Here we aim to optimize ...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117887
更新日期：2021-06-01 00:00:00
abstract：:Zein films incorporated with catechin/β-cyclodextrin inclusion complex nanoparticles (CINPs) were developed, and the structure, physicochemical, antioxidant and release properties of the films were characterized. FT-IR results indicated that intermolecular hydrogen bonds were formed between the CINPs and zein. XRD ana...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117877
更新日期：2021-06-01 00:00:00
abstract：:Almost all plant cells are surrounded by a wall constructed of co-extensive networks of polysaccharides and proteoglycans. The capability to analyse cell wall components is essential for both understanding their complex biology and to fully exploit their numerous practical applications. Several biochemical and immunol...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117866
更新日期：2021-06-01 00:00:00
abstract：:The properties of aqueous suspensions of cellulose nanocrystals (CNC) and their casted films are revised. The bio-nanoparticles are briefly introduced, including modifications of the crystals and the suspending media. The formation of CNC-derived liquid crystals (LC) and their resulting rheological behavior are presen...
journal_title：Carbohydrate polymers
pub_type： 杂志文章,评审
doi：10.1016/j.carbpol.2021.117848
更新日期：2021-06-01 00:00:00
abstract：:In this study, a polysaccharide from marine alga Acanthophora spicifera (PAs) was isolated and structurally characterized. Its protective potential against chemically-induced gastric mucosa injury was evaluated. The gel permeation chromatography experiments and spectroscopy spectrum showed that PAs is a sulfated polys...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117829
更新日期：2021-06-01 00:00:00
abstract：:The efficacy and mode of action of biodegradable chitosan (CS) and carboxymethyl chitosan (CMCS) organic polymer nanoparticles (NPs) on insects were studied. The prepared CS/CMCS-NPs were spherical with a particle size of 142.1 ± 2.0 nm. The swelling test showed that they were pH-sensitive, and the swelling rate was 5...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117839
更新日期：2021-05-15 00:00:00
abstract：:A bio-based pressure-responsive sensor with adjustable structural color is prepared by combining aerogel skeleton of cellulose nanocrystals (CNCs)/poly(ethylene glycol) (PEG) obtained via the ice-templating method with flexible polyacrylamide (PAAM) elastomer. The white aerogel is composed of consecutive ribbons, demo...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117823
更新日期：2021-05-15 00:00:00
abstract：:In the present study, a novel synthetic tissue adhesive material capable of sealing wounds without the use of any crosslinking agent was developed by conjugating thermosensitive hexanoyl glycol chitosan (HGC) with gallic acid (GA). The degree of N-gallylation was manipulated to prepare GA-HGCs with different GA conten...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117808
更新日期：2021-05-15 00:00:00
abstract：:The polysaccharide (DRP) was gained from dandelion roots by ultrasonic-assisted enzymatic extraction (UAEE) followed by two-step column purification. Then selenylation of DRP has been accomplished by HNO3-Na2SeO3 method. sDRP-1 and sDRP-2 with the selenium content of 170 ± 1.13 and 710 ± 4.00 μg/g were prepared for fu...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117796
更新日期：2021-05-15 00:00:00
abstract：:To deal with serious environmental damage resulting from plastic packaging materials, biodegradable films using natural products have gained considerable attention. Here, we provide a simple, fast, and environmentally-friendly route to construct a biodegradable film using chitosan (CS), bacterial cellulose (BC), and c...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117778
更新日期：2021-05-15 00:00:00
abstract：:Acceptance of new rice genotypes demanded by rice value chain depends on premium value of varieties that match consumer demands of regional preferences. High throughput prediction tools are not available to breeders to classify cooking and eating quality (CEQ) ideotypes and to capture texture of varieties. The pasting...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117766
更新日期：2021-05-15 00:00:00
abstract：:This study reports the performance of FucoPol, a fucose-containing bacterial polysaccharide, as a photostable agent with high absorption yield at concentrations as low as 0.02 % (w/v). FucoPol is non-cytotoxic, efficiently protects from UVA and UVB at concentrations of 0.02-2 % (w/v) and 0.2-2 % (w/v), respectively, h...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117761
更新日期：2021-05-01 00:00:00
abstract：:In this work, hydroxypropyl-β-cyclodextrin-polyurethane magnetic nanoconjugates/reduced graphene oxide (HPMNPU/GO) supramolecules were prepared. The adsorbent was characterized using FTIR and SEM. The adsorbent was evaluated for its efficiency to remove Cr6+ and Pb2+ from aqueous solutions through batch adsorption stu...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117731
更新日期：2021-05-01 00:00:00
abstract：:Sufficient hydroxyl moiety, ease of accessibility, biodegradability and reaction compatibility with other molecules make starch a basic ingredient for polymeric synthesis and to prepare encapsulated controlled release fertilizers. This article aims to prepare biodegradable clay-polymeric (starch/PVA) blended encapsula...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117679
更新日期：2021-05-01 00:00:00
abstract：:This study introduces a hydrophobically modified bacterial cellulose nanofibrils (BCNF)-stabilized Pickering emulsion system, which can limit the influx of metal ions through the interface. We showed that the C18 alkyl chain-grafted BCNF (C18BCNF) can readily associate to generate a resilient thin membrane at the oil-...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117730
更新日期：2021-04-15 00:00:00
abstract：:In comparison to conventional nanoparticles biopolymer like chitosan based nanoparticles will be of much lower cost, non-toxic and more compatible with polymer membranes. As a cationic polymer surfactant chitosan is able to generate polymer nanoparticles during emulsion polymerization of methyl methacrylate. According...
journal_title：Carbohydrate polymers
pub_type： 杂志文章
doi：10.1016/j.carbpol.2021.117704
更新日期：2021-04-15 00:00:00
