Abstract：
:Folic acid (FA) is the natural form of water-soluble vitamins widely found in most plants and animal products and its deficiency leads to several human body abnormalities. The advancements of metal nanoclusters are highly increasing due to their molecule-like optical properties and attractive applications. Because of increasingly demand of noble metal nanoclusters as sensing templates, different synthesis methods have been developed for facile synthesis of noble metal nanoclusters. Herein, red-emitting fluorescent bovine serum albumin (BSA)-capped Au-Ag bimetallic NCs are facilely synthesized through green one-pot synthetic approach. The effect of silver on the fluorescence properties of Au NCs was investigated and it was found that introduction of silver can enhance the fluorescence intensity. The fluorescence intensity of the as-prepared Au-Ag nanoclusters gets quenched in the presence of folic acid in an aqueous medium and it was used as ultrasensitive sensing probe for FA detection. The developed Au-Ag NCs-based sensing probe shows linear response in the wide range of 0-100 μM and the detection limit is as low as 0.47 nM. Its applicability has also been confirmed successfully in real human serum, urine and FA tablet samples. Due to the high stability, sensitivity and selectivity, the developed bimetallic cluster sensing system is highly promising to be applied in the pharmaceutical and clinical laboratories.
journal_name
Talantajournal_title
Talantaauthors
Fereja SL,Li P,Guo J,Fang Z,Zhang Z,Zhuang Z,Zhang X,Liu K,Chen Wdoi
10.1016/j.talanta.2021.122469keywords:
["Bovine serum albumin","Fluorescence","Folic acid","Metal nanocluster","Quenching","Sensing probe"]subject
Has Abstractpub_date
2021-10-01 00:00:00pages
122469eissn
0039-9140issn
1873-3573pii
S0039-9140(21)00390-8journal_volume
233pub_type
杂志文章相关文献
TALANTA文献大全abstract：:Urine is a biofluid easy to collect through a non-invasive technique that allows collecting a large volume of sample. The use of urine for disease diagnosis is not yet well explored. However, it has gained attention over the last three years. It has been applied in the diagnosis of several illnesses such as kidney dis...
journal_title：Talanta
pub_type： 杂志文章,评审
doi：10.1016/j.talanta.2021.122345
更新日期：2021-08-01 00:00:00
abstract：:The complex natural organic matter of the Suwannee River fulvic acid (SRFA) standard was analyzed by online reversed-phase chromatography with Orbitrap MS/MS using collision-induced dissociation (CID). The number of isobars per nominal mass could be reduced to a single dominantly abundant species in a chromatographic ...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122320
更新日期：2021-08-01 00:00:00
abstract：:In this study, sarcosine metal-coded hydrogel magnetic molecularly imprinted polymer (Hydro-MeC-MMIP) has been fabricated and coupled to on-column derivatization capillary electrophoresis (CE). As a metal-coding approach, sarcosine-Cu2+-ligand (Sar-Cu2+-L) chelate complex was introduced as a template to overcome the p...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122309
更新日期：2021-08-01 00:00:00
abstract：:Exposure to colorless ammonia gas may lead to damage in human organs or even death. Herein, we describe facile fabrication of an environmentally-friendly, portable, reversible, and sensitive solid-state colorimetric cellulose (Cell)/anthocyanin (Anth) vapochromic sensor that exhibits instant visual color change to bot...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122292
更新日期：2021-08-01 00:00:00
abstract：:Iron speciation in seawater is of the utmost importance as this element plays a central role in the regulation of primary productivity. Here we present the development of a CLE-CSV (Competitive Ligand Equilibration-Cathodic Stripping Voltammetry) procedure for iron speciation in seawater avoiding for the first time th...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122300
更新日期：2021-07-01 00:00:00
abstract：:Aberrant transcription factors (TFs) activities are closely related to the occurrence and development of various diseases. Herein, we presented a fluorescence-encoded microsphere-based approach for TFs detection coupling with common DNA footprinting assay. Target TFs specifically bound the binding sites of double-stra...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122272
更新日期：2021-07-01 00:00:00
abstract：:The majority of existing advanced automated cell counter instruments used in laboratory settings are complex, expensive, and bulky. As a result, applications of these instruments have been limited to such laboratories. Meanwhile, in many rural areas and developing countries, clinical laboratories equipped with optical...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122244
更新日期：2021-06-01 00:00:00
abstract：:Developing efficient and sensitive cytosensing method has great significance for the detection of low abundant circulating tumor cells (CTCs). Electrochemiluminescence (ECL) biosensor, as an attractive analytical tool, has shown a great potential in sensitive cell counting. Its detection efficiency is strongly depende...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122230
更新日期：2021-06-01 00:00:00
abstract：:Flexible transparent SERS substrates have aroused great interest as a rapid and in situ detection method for trace chemicals. We demonstrate a one-step and environmentally friendly method to fabricate flexible fluorinated ethylene propylene (FEP) surface plasmon resonance film by femtosecond laser induced plasma assis...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122204
更新日期：2021-06-01 00:00:00
abstract：:Gold nanoparticles are known to exhibit appealing intrinsic plasmon-modulated photoluminescence (PL) properties which can be explored in various fluorescence-based sensing applications. In this paper, we evaluate the PL of different-sized gold nanospheres (AuNSs) under one-photon excitation (1PE) and develop a sensiti...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122242
更新日期：2021-06-01 00:00:00
abstract：:It is widely accepted that nanotechnology attracted more interest because of various values that nanomaterial applications offers in different fields. Recently, researchers have proposed nanomaterials based electrochemical sensors and biosensors as one of the potent alternatives or supplementary analytical tools to th...
journal_title：Talanta
pub_type： 杂志文章,评审
doi：10.1016/j.talanta.2020.122075
更新日期：2021-06-01 00:00:00
abstract：:High-resolution continuum source molecular absorption spectrometry (HR-CS MAS) has been developing fast for fluorine determination, but neither flame nor graphite furnace technique have ever been applied for the analysis of petroleum or its products. Hydrogen fluoride can be applied in technologies of gasoline compone...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122205
更新日期：2021-05-15 00:00:00
abstract：:Seven artworks representing the diversity of paints used around the 1960s and created by German and Italian painters (J. Albers, A. Bonalumi, L. Boille, T. Scialoja and M. Schifano) were studied on-site at the Galleria Nazionale d'Arte Moderna (Rome) with mobile instruments. We present a methodology based on Specular ...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122159
更新日期：2021-05-15 00:00:00
abstract：:Lung cancer is one of the common malignant tumors with a high incidence and mortality rate. Targeted therapies are efficient on lung cancer patients with specific gene mutations. Circulating tumor cells (CTCs) are used for liquid biopsy, providing genetic information for lung cancer treatment selection and prognosis. ...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122172
更新日期：2021-05-01 00:00:00
abstract：:In this work, two microwave-assisted sample preparation methods based on combustion and ultraviolet digestion for futher determination of Br, Cl, and I in blood by inductively coupled plasma mass spectrometry were proposed. For microwave-induced combustion (MIC), blood was spotted on square pieces of Munktell TFN pape...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122157
更新日期：2021-05-01 00:00:00
abstract：:Many phosphoprotein biomarkers have been proved to exist in body fluids such as serum and urine, however, there is absence of rapid and efficient separation and identification method. In this study, we proposed to combine metal oxide affinity chromatography (MOAC), molecular imprinting technology (MIT) and matrix-assi...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122143
更新日期：2021-05-01 00:00:00
abstract：:In this work, nanoporous gold (NPG) was prepared according to three different approaches, such as (i) anodization-electrochemical reduction (A-ECR, NPGA), (ii) dynamic hydrogen bubble template (DHBT, NPGB), and (iii) the combination of both methods (NPGA+B). Field-emission scanning electron microscopy (FE-SEM) and cyc...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122130
更新日期：2021-05-01 00:00:00
abstract：:Chemical speciation is a relevant topic in environmental chemistry since the (eco)toxicity, bio (geo)chemical cycles, and mobility of a given element depend on its chemical forms (oxidation state, organic ligands, etc.). Maintaining the chemical stability of the species and avoiding equilibrium disruptions during the ...
journal_title：Talanta
pub_type： 杂志文章,评审
doi：10.1016/j.talanta.2021.122119
更新日期：2021-05-01 00:00:00
abstract：:A revolutionary impact on the pharmaceutical and biomedical applications has been arisen in the few years to come as a result of the advances made in magnetic nanoparticles (MNPs) research. The use of MNPs opens wide opportunities in diagnostics, drug and gene delivery, in vivo imaging, magnetic separation, and hypert...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122108
更新日期：2021-05-01 00:00:00
abstract：:Standard two/three dimensional (2D/3D)-cell culture platforms have facilitated the understanding of the communications between various cell types and their microenvironments. However, they are still limited in recapitulating the complex functionalities in vivo, such as tissue formation, tissue-tissue interface, and me...
journal_title：Talanta
pub_type： 杂志文章,评审
doi：10.1016/j.talanta.2021.122097
更新日期：2021-05-01 00:00:00
abstract：:Cigarette smoking is considered to be a risk factor for several chronic diseases and even premature death. However, despite the importance of this detrimental habit, little seems known in terms of the overall toxicity potential of its ingredients in humans. In this study, a panel of genetically modified bioluminescent...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2020.122076
更新日期：2021-05-01 00:00:00
abstract：:In pesticide residues analysis, the drift is the difference between the concentration of two bracketing calibrations in the same batch. According to the SANTE/12682/2019 guideline a criterion of ±30% must be met or positive samples should be reanalyzed. This study aimed to investigate, for the first time, the efficien...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2020.121970
更新日期：2021-04-01 00:00:00
abstract：:Recent advances in benchtop vacuum ultraviolet (VUV) spectrometers have yielded effective universal detectors for gas chromatography (GC). The ability of these detectors to acquire absorbance spectra from 125 nm to 430 nm poses an alternative to the gold standard of mass spectrometry (MS) as a sensitive and selective ...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2021.122081
更新日期：2021-04-01 00:00:00
abstract：:The development of convenient and efficient fluorescence techniques is of great significance for selective detection and precise determination of biotoxic N2H4 in human health and environmental sciences. By the pre-organization-assisted template synthesis, disclosed here is a luminescent Sm(III) macrocycle-based probe...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2020.122065
更新日期：2021-04-01 00:00:00
abstract：:Drugs in the bloodstream are available in both free and bound forms in which the free drug is responsible for pharmacological activities. Since protein binding determines the amount of free concentration of the drug in the blood, determining the protein binding in the early stages of drug discovery and development is ...
journal_title：Talanta
pub_type： 杂志文章,评审
doi：10.1016/j.talanta.2020.122052
更新日期：2021-04-01 00:00:00
abstract：:Although many copper-based antimicrobial compounds have been developed to control pathogenic bacteria and fungi in plants and applied for crop protection, there is evidence that several plant pathogens have developed resistance to copper-based antimicrobial compounds, including some Xanthomonas species. Xylella is a b...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2020.122040
更新日期：2021-04-01 00:00:00
abstract：:Understanding mechanisms of materials deterioration during service life is fundamental for their confident use in the building sector. This work presents analysis of time series of data related to wood weathering acquired at three scales (molecular, microscopic, macroscopic) with different sensors. By using several co...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2020.122024
更新日期：2021-04-01 00:00:00
abstract：:Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the cause of Coronavirus Disease 2019 (COVID-19), poses extraordinary threats and complex challenges to global public health. Quantitative measurement of SARS-CoV-2 antibody titer plays an important role in understanding the patient-to-patient variability o...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2020.122004
更新日期：2021-04-01 00:00:00
abstract：:Diagnostic tools play significant roles in the fight against COVID-19 and other pandemics. Existing tests, such as RT-qPCR, have limitations including long assay time, low throughput, inadequate sensitivity, and suboptimal portability. Emerging biosensing technologies hold the promise to develop tests that are rapid, ...
journal_title：Talanta
pub_type： 杂志文章,评审
doi：10.1016/j.talanta.2020.121986
更新日期：2021-04-01 00:00:00
abstract：:The present study describes the development of a novel solvent-free vortex-assisted dispersive liquid-liquid microextraction alternative based on a natural essential oil as extracting solvent (VA-EO-DLLME) for the determination of N,N-dimethyltryptamine (DMT), harmine (HRM), harmaline (HRL) and tetrahydroarmine (THH) ...
journal_title：Talanta
pub_type： 杂志文章
doi：10.1016/j.talanta.2020.121976
更新日期：2021-04-01 00:00:00
