Abstract：
:Drugs re-purposing due to COVID-19 virus has declared a number of useful candidates for treatment and prevention of the virus. Ivermectin (IVM) has gained much popularity due to a strong background of magical applications against a broad spectrum of pathogens. The in- vitro studies of ivermectin have shown promise, the thorough clinical trials of its efficacy in the treatment and prevention of SARS-CoV-2 are still warranted. Useful strategies for analyzing projected use of IVM in human coronaviruses might be developed. It may be done by concluding ongoing clinical trials and culturing lessons from IVM usage in veterinary practice. The potential toxicity and careful dosage analyses are urgently required before declaring it as an anti-SARS-CoV-2 drug candidate. This manuscript overviews the background and potential threats associated with the off-label use of IVM as prophylactic drug or treatment option against COVID-19 virus.
journal_name
J Mol Structjournal_title
Journal of molecular structureauthors
Zaheer T,Pal K,Abbas RZ,Torres MDPRdoi
10.1016/j.molstruc.2021.130808keywords:
["CVID-19 virus","Drug analysis","Ivermectin","Safety","Threats"]subject
Has Abstractpub_date
2021-11-05 00:00:00pages
130808eissn
0022-2860issn
1872-8014pii
S0022-2860(21)00941-8journal_volume
1243pub_type
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