听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览Genetic Testing and Molecular Biomarkers期刊下所有文献
  • Methylation of the Sclerostin (SOST) Gene in Serum Free DNA: A New Bone Biomarker?

    abstract:: Introduction: Cell-free DNA (cfDNA) methylation is an important molecular biomarker, which provides information about the regulation of gene expression in the tissue of origin. There is an inverse correlation between SOST gene methylation and expression levels. ...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2020.0172

    authors: Del Real A,Perez-Campo FM,Perez-Nuñez MI,Sañudo C,Santurtun A,Garcia-Ibarbia C,Garcia-Unzueta MT,Fraga MF,Fernandez AF,Valero MC,Laguna E,Riancho JA

    更新日期:2021-01-01 00:00:00

  • Improvement of a Rapid and Highly Sensitive Method for the Diagnosis of the Mitochondrial m.1555A>G Mutation Based on a Single-Stranded Tag Hybridization Chromatographic Printed-Array Strip.

    abstract:: Aims: Pathogenic variants in mitochondrial DNA are known to be associated with sensorineural hearing loss (SNHL) and aminoglycoside-induced HL. Among them, the m.1555A>G mutation is the most common. Thus, a rapid and easy companion diagnostic method for this mutation would...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章,随机对照试验

    doi:10.1089/gtmb.2020.0105

    authors: Isaka Y,Nishio SY,Hishinuma E,Hiratsuka M,Usami SI

    更新日期:2021-01-01 00:00:00

  • Possible Association of PER2/PER3 Variable Number Tandem Repeat Polymorphism Variants with Susceptibility and Clinical Characteristics in Pancreatic Cancer.

    abstract:: Objective: Pancreatic cancer (PC) is a serious disease with poor outcomes, and its prevalence has been increasing steadily. The circadian rhythm (CR) is involved in multiple physiological events and maintains homeostasis. Alterations in the CR elevate the risk of developin...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2020.0179

    authors: Dagmura H,Yiğit S,Nursal AF,Duman E,Gumusay O

    更新日期:2020-12-29 00:00:00

  • The SELS rs34713741 Polymorphism Is Associated with Susceptibility to Colorectal Cancer and Gastric Cancer: A Meta-Analysis.

    abstract:: Aims: The selenoprotein S (SELS) gene has been suggested to be an important factor in the development of multiple diseases, including gastric cancer (GC) and colorectal cancer (CRC). However, the association between the SELS gene rs34713741 polymorphism and risk of GC and ...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2020.0099

    authors: Li J,Zhu Y,Zhou Y,Jiang H,Chen Z,Lu B,Shen X

    更新日期:2020-12-01 00:00:00

  • Clinical Significance of POM121 Expression in Lung Cancer.

    abstract:: Aims: The aim of this study was to examine the RNA and protein expression levels and clinical significance of the pore membrane protein 121 kDa (POM121) in lung cancer. Materials and Methods: Paired lung cancer and adjacent non...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2020.0053

    authors: Zhang S,Zheng C,Li D,Bei C,Zhang H,Tian R,Song X,Zhu X,Tan S

    更新日期:2020-12-01 00:00:00

  • A Novel Mutation in the IL6R Gene Identified in a Family with Asthma Patients.

    abstract:: Background: Allergic diseases, including asthma, atopic dermatitis, allergic rhinitis, and food allergies, are caused by both environmental and genetic factors. The allergic condition, where genetic factors make up the largest proportion (up to 95%), is asthma. ...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2020.0081

    authors: Trueb B,Zhuang L,Villiger PM

    更新日期:2020-10-01 00:00:00

  • Overexpression of Fatty Acid 2-Hydroxylase is Associated with an Increased Sensitivity to Cisplatin by Ovarian Cancer and Better Prognoses.

    abstract:: Background: Recent discoveries indicate that the enzyme fatty acid 2-hydroxylase (FA2H) is associated with biological behavior and can be used for outcome prediction in several types of cancers. Such relevancy, however, between FA2H and ovarian cancer is not clear. Therefo...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2019.0259

    authors: Qi T,Wu D,Duan Z,Chen C,Qiu J,Kang J

    更新日期:2020-10-01 00:00:00

  • Sequence Variants in the WNT10B and TP63 Genes Underlying Isolated Split-Hand/Split-Foot Malformation.

    abstract:: Aims: Split-hand/split-foot malformation (SHFM) is a developmental and congenital limb malformation characterized by variable degrees of medial clefting or absence of one or more digits in hands and/or feet. The aim of this study was to identify the underlying cause of thr...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2020.0024

    authors: Bilal M,Hayat A,Umair M,Ullah A,Khawaja S,Malik E,Burmeister M,Bibi N,Umm-E-Kalsoom,Memon MI,Basit S,Ahmad W,Khan B

    更新日期:2020-09-01 00:00:00

  • Identification of Potential Hub Genes and Signal Pathways Promoting the Distinct Biological Features of Cord Blood-Derived Endothelial Progenitor Cells Via Bioinformatics.

    abstract:: Background: Numerous studies, ranging from the alleviation of tissue ischemia to the assessment of cancer prognosis, have demonstrated the fundamental biological differences between human umbilical cord blood-derived endothelial progenitor cells (CB-EPCs) and adult periphe...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2019.0272

    authors: Wang Q,Chen S,Wu J,Liu D,Jiang N,Wang B,Zhai J,Liu Z

    更新日期:2020-09-01 00:00:00

  • Intelligent Ratio: A New Method for Carrier and Newborn Screening in Spinal Muscular Atrophy.

    abstract:: Aim: Spinal muscular atrophy (SMA) is an inherited, autosomal recessive neuromuscular disease that causes high morbidity and mortality. The prevalence is 1-2/100,000, while the incidence is 1/6000-1/10,000 among live births. Due to the high carrier frequency (1/40-1/60) of...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2020.0085

    authors: Cavdarli B,Ozturk FN,Guntekin Ergun S,Ergun MA,Dogan O,Percin EF

    更新日期:2020-09-01 00:00:00

  • Association of the Genetic Polymorphisms rs6259 and rs727428 of the SHBG Gene with Polycystic Ovary Syndrome Risk: A Meta-Analysis.

    abstract:: Background: Studies investigating the relationship between polymorphisms of the sex hormone-binding globulin (SHBG) gene and polycystic ovary syndrome (PCOS) have reported differing results. Therefore, the present meta-analysis was performed to clarify the effects of the S...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2019.0229

    authors: Liao X,Cao S

    更新日期:2020-08-01 00:00:00

  • Serum Level and Gene Expression of Interleukin-15 Do Not Correlate with Villous Atrophy in Celiac Disease Patients.

    abstract:: Background and Aims: Interleukin-15 (IL-15) is a key player in the pathogenesis of celiac disease (CD). We investigated the functional role of IL-15 in the process of epithelial cell phenotypic modification at different stages of CD. Materials and ...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2019.0265

    authors: Aghamohamadi E,Kokhaei P,Rostami-Nejad M,Pak F,Rostami K,Moradi A,Pourhoseingholi MA,Chaleshi V,Masotti A,Zali MR

    更新日期:2020-08-01 00:00:00

  • Association of Single Nucleotide Polymorphisms of the IL-6, IL-10, and TNF-α Genes with Susceptibility to Gestational Diabetes Mellitus.

    abstract:: Objective: To investigate any associations between the single nucleotide polymorphisms (SNPs) at the interleukin-6 (IL-6) rs1800796, interleukin-10 (IL-10) rs1800896, and the tumor necrosis factor-alpha (TNF-α) rs1800629 loci with gestational diabetes mellitus (GDM) suscep...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2020.0069

    authors: Wei Q,Chen X,Chen H

    更新日期:2020-07-01 00:00:00

  • The Frequency of the Minor Polymorphisms in the CYP2C19, VEGFR-2 Genes, and Clinical Outcomes in Russian and Buryat Patients with Acute Coronary Syndrome.

    abstract::Aim: To determine the differences in the frequencies of polymorphic variants at the rs4244285(*2), rs4986893 (*3), rs12248560 (*17), loci of the CYP2C19 gene, and the rs2305948 locus of the VEGFR-2 gene in patients receiving clopidogrel treatment as part of a 30-day clinical outcome trial in the Russian and Buryat reg...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2019.0216

    authors: Zelenskaya EM,Lifshits GI,Nikolaev KY,Donirova OS,Altayev VD,Apartsin KA,Voronina EN,Protasov KV,Sychev DA

    更新日期:2020-06-01 00:00:00

  • A Novel PAX3 Mutation in a Chinese Family with Waardenburg Syndrome Type 1.

    abstract:: Aims: To determine the clinical characteristics and genetic cause of Waardenburg syndrome type 1 (WS1) in a Chinese family. Materials and Methods: Evaluations, including history, clinical features, and audiological tests, were ...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2019.0231

    authors: Li S,Guo M,Ruan B,Liu Y,Cui X,Han W,Li R

    更新日期:2020-05-01 00:00:00

  • DEFB4A Promoter Polymorphism Is Associated with Chronic Periodontitis: A Case-Control Study.

    abstract:: Background: Human β-defensin-2 is an antimicrobial peptide with antibiotic properties secreted by the oral cavity to protect the host against microbial attack. The inter-individual differences in defensin expression profiles due to genetic variation might be partly respons...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2019.0218

    authors: Kurt-Bayrakdar S,Ozturk A,Kara N

    更新日期:2020-03-01 00:00:00

  • Applications of Next-Generation Sequencing in Neoantigen Prediction and Cancer Vaccine Development.

    abstract::Next-generation sequencing has changed the face of cancer immunotherapy research by making tumor-specific cancer vaccines a reality. Whole exome sequencing and RNA sequencing combined with bioinformatic pipelines allow the prediction of neoantigen targets for cancer vaccines. In this review, we discuss the preclinical...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章,评审

    doi:10.1089/gtmb.2018.0211

    authors: Lancaster EM,Jablons D,Kratz JR

    更新日期:2020-02-01 00:00:00

  • Analysis of Polymorphisms in the MATN3 and DOT1L Genes and CTX-II Urinary Levels in Patients with Knee Osteoarthritis in a Northeast Mexican-Mestizo Population.

    abstract:: Aims: To investigate the possible roles of the single nucleotide polymorphisms (SNPs) MATN3 (rs77245812) and DOT1L (rs12982744) with susceptibility to knee osteoarthritis (KOA) among mestizos from the northeast region of Mexico. In addition, we analyzed the relationship of...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 临床试验,杂志文章

    doi:10.1089/gtmb.2019.0179

    authors: García-Alvarado FJ,Delgado-Aguirre HA,Rosales-González M,González-Martínez MDR,Ruiz-Flores P,González-Galarza FF,Arellano Perez Vertti RD

    更新日期:2020-02-01 00:00:00

  • Exploration of the Serum Interleukin-17 and Interleukin-27 Expression Levels in Children with Bronchial Asthma and Their Correlation with Indicators of Lung Function.

    abstract:: Aims: To investigate the expression levels of serum interleukin-17 (IL-17) and interleukin-27 (IL-27) in children with bronchial asthma and to correlate these expression levels with lung function indicators. Methods: A total of...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2019.0155

    authors: Liu Z,Niu C,Ying L,Zhang Q,Long M,Fu Z

    更新日期:2020-01-01 00:00:00

  • κ Opioid Receptor 1 Single Nucleotide Polymorphisms were Associated with the Methadone Dosage.

    abstract:: Background: Heroin use disorder (HUD) is a complex brain disease that includes multiple phenotypes. Heroin acts primarily as a mu-opioid receptor (OPRM1) agonist. The κ opioid receptor 1 (OPRK1) is critically involved in abstinence and remission. Multiple studies confirm t...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2019.0159

    authors: Zhang Q,Shi M,Tang H,Zhong H,Lu X

    更新日期:2020-01-01 00:00:00

  • Association Between Period 3 Gene Polymorphisms and Adverse Effects of Antidepressants for Major Depressive Disorder.

    abstract:: Aims: Circadian rhythm genes including Period 3 (Per3) are associated with major depressive disorder (MDD) and have an effect on the patient's response to selective serotonin reuptake inhibitor (SSRI) antidepressants. The aim of this study was to identify possible associat...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2019.0065

    authors: Xu Y,Ma H,Zhao T,Wen D,Wen Y,Qiao D,Liu Z

    更新日期:2019-12-01 00:00:00

  • A Comparative Study of ARHI Imprinted Gene Detection and Fine-Needle Aspiration Cytology in the Differential Diagnosis of Benign and Malignant Thyroid Nodules.

    abstract:: Aims: To compare fine-needle aspiration cytology (FNAC) with imprinted gene detection in the differential diagnosis of benign and malignant thyroid nodules. Methods: A total of 34 patients (35 cases of thyroid nodules) were exa...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2019.0028

    authors: Zou D,Wu C,Miao J,Shao Q,Huang W,Huang J,Wu G,Zhang Q

    更新日期:2019-09-01 00:00:00

  • The Impact of Vitamin D Receptor Gene Polymorphisms on the Susceptibility of Diabetic Vascular Complications: A Meta-Analysis.

    abstract:: Background: To determine whether vitamin D receptor (VDR) gene polymorphisms are correlated with susceptibility to diabetic vascular complications. Methods: We included all eligible studies, and used Stata12.0 to calculate the ...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章,meta分析

    doi:10.1089/gtmb.2019.0037

    authors: Song N,Yang S,Wang YY,Tang SQ,Zhu YQ,Dai Q,Zhang H

    更新日期:2019-08-01 00:00:00

  • Mutation Analysis of the IDUA Gene in Iranian Patients with Mucopolysaccharidosis Type 1: Identification of Four Novel Mutations.

    abstract:: Background and Purpose: Mucopolysaccharidosis 1 (MPS1) is an autosomal recessive disorder of a lysosomal enzyme called alpha-l-iduronidase caused by mutations in the IDUA gene. This enzyme is responsible for the degradation of the mucopolysaccharides, heparan sulfate, and ...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2019.0022

    authors: Kamranjam M,Alaei M

    更新日期:2019-08-01 00:00:00

  • Molecular Prognostic Value of Circulating Epstein-Barr Viral DNA in Nasopharyngeal Carcinoma: A Meta-Analysis of 27,235 Cases in the Endemic Area of Southeast Asia.

    abstract:: Aims: This meta-analysis evaluated the value of using Epstein-Barr virus (EBV) DNA titers as a predictive factor in assessing the clinical course of nasopharyngeal carcinoma (NPC) patients in Southeast Asia. Methods: A systemat...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章,meta分析

    doi:10.1089/gtmb.2018.0304

    authors: Xie X,Ren Y,Wang K,Yi B

    更新日期:2019-07-01 00:00:00

  • Genetic Polymorphisms of miR-149 Associated with Susceptibility to Both Pulmonary and Extrapulmonary Tuberculosis.

    abstract:: Background: Single nucleotide polymorphisms (SNPs) within precursor microRNAs (miRNAs) can affect the expression of the miRNAs and may be involved in the pathogenesis of pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB). Aims: ...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2019.0003

    authors: Chen WW,Wan B,Zhang R,Cao W,Liang L,Zhao YL,Chen J,Yue J

    更新日期:2019-07-01 00:00:00

  • Identification of a Novel Frameshift Variant of POU3F4 and Genetic Counseling of Korean Incomplete Partition Type III Subjects Based on Detailed Genotypes.

    abstract:: Aim: The aim of this study was to report a novel POU Class 3 Homeobox 4 (POU3F4) variant and to provide further guidance on genetic counseling for incomplete partition (IP) type III families in the Korean population by showing two new contrasting cases in terms of genotype...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2018.0296

    authors: Jang JH,Oh J,Han JH,Park HR,Kim BJ,Lee S,Kim MY,Lee S,Oh DY,Choung YH,Choi BY

    更新日期:2019-06-01 00:00:00

  • Skin Autofluorescence Is Associated with Diabetic Peripheral Neuropathy in Chinese Patients with Type 2 Diabetes: A Cross-Sectional Study.

    abstract:: Background: Diabetic peripheral neuropathy (DPN) affects nearly 50% of the diabetic population. Advanced glycation end products, measured through skin autofluorescence (SAF), play an important role in the diagnosis and prevention of DPN. To date, however, no relevant study...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2018.0328

    authors: Wan L,Qin G,Yan W,Sun T

    更新日期:2019-06-01 00:00:00

  • Association Between the IL-10-1082G/A, IL-10-592A/C, and IL-10-819G/A Polymorphisms and Atopic Dermatitis Susceptibility: A Meta-Analysis.

    abstract:: Aims: The aim of this study was to summarize the currently available evidence on the associations between the IL-10-1082G/A, IL-10-592A/C, and IL-10-819G/A polymorphisms and susceptibility to atopic dermatitis (AD). Materials and Methods: ...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章,meta分析

    doi:10.1089/gtmb.2018.0276

    authors: Zhao J,Chen ZY,Li LF

    更新日期:2019-05-01 00:00:00

  • Design of a Targeted Sequencing Assay to Detect Rare Mutations in Circulating Tumor DNA.

    abstract:BACKGROUND:Qualitative and quantitative detection of circulating tumor DNA (ctDNA) is a liquid biopsy technology used for early cancer diagnosis. However, the plasma ctDNA content is extremely low, so it is difficult to detect somatic mutations of tumors using conventional sequencing methods. Target region sequencing (...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2018.0173

    authors: Chen J,Chen J,He F,Huang Y,Lu S,Fan H,Wang M,Xu R

    更新日期:2019-04-01 00:00:00

  • Dual-Targeting of miR-124-3p and ABCC4 Promotes Sensitivity to Adriamycin in Breast Cancer Cells.

    abstract:AIMS:Increasing evidence links the abnormal expression of microRNAs and ATP-binding cassette subfamily C member 4 (ABCC4) with tumor development and progression, as well as with chemoresistance. Our aims were to determine the therapeutic potential of targeting both miR-124-3p and ABCC4 in breast cancer cells and to det...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2018.0259

    authors: Hu D,Li M,Su J,Miao K,Qiu X

    更新日期:2019-03-01 00:00:00

  • Carrying the T Allele of the SNP rs574344, an eQTL of GSTM1, Contributes to Longevity in the Han Chinese Population.

    abstract:BACKGROUND:There has been recent recognition that the GSTM1 gene is associated with successful aging and longevity. It has been hypothesized that individuals with a GSTM1 deletion are at a greater risk for developing a plethora of diseases. This study was carried out to investigate the association between the rs574344 ...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2018.0178

    authors: Zhang Y,Zhang S,Yan D,Pan H,Liu B,Li T,Wang X,Cai W,Wang B

    更新日期:2019-01-01 00:00:00

  • Higher DNA Yield for Epidemiological Studies: A Better Method for DNA Extraction from Blood Clot.

    abstract:BACKGROUND:Blood clots can be used to extract DNA, but they are not as widely used as whole blood or buffy coats. This is due not only because of the relatively low DNA yields and quality obtained from blood clots, but also because sampling prior to DNA extraction is more difficult. METHODS:To solve these problems, we...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2018.0131

    authors: Zhou G,Du Y,Wu Y,Wang WC

    更新日期:2019-01-01 00:00:00

  • Screening of AIP Gene Variations in a Cohort of Turkish Patients with Young-Onset Sporadic Hormone-Secreting Pituitary Adenomas.

    abstract:: Aims: Aryl hydrocarbon receptor-interacting protein (AIP) gene mutations have long been associated with apparently sporadic pituitary adenomas (PAs) with a prevalence range of 0-12%. The aim of this study was to evaluate the frequency of germline AIP variations in a large ...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2018.0133

    authors: Tuncer FN,Çiftçi Doğanşen S,Serbest E,Tanrıkulu S,Ekici Y,Bilgiç B,Yarman S

    更新日期:2018-12-01 00:00:00

  • Genetic and Functional Analyses of Two Missense Mutations in the Transcription Factor FOXL2 in Two Chinese Families with Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome.

    abstract:BACKGROUND:Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES) is a rare autosomal-dominant inherited disease. This study was carried out to investigate the genetic and functional changes within the FOXL2 gene in two Chinese families with BPES. MATERIALS AND METHODS:DNA was extracted from the peripheral blood ...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2018.0064

    authors: Li H,Gu Y

    更新日期:2018-10-01 00:00:00

  • Association of Desmin Gene Variant rs1058261 with Cardiovascular Disease, the TAMRISK Study.

    abstract:AIMS:Since desmin expression is diminished in vascular smooth muscle cells during reparative processes, we wanted to study whether a common intragenic single nucleotide polymorphism at nucleotide position 828 (rs1058261) of the DES gene associates with hypertension, cerebrovascular complications, and all cardiovascular...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2018.0118

    authors: Piesanen J,Kunnas T,Nikkari ST

    更新日期:2018-09-01 00:00:00

  • Association Between the SNP rs143383 + 104T/C in the GDF5 Gene and the Risk of Knee Osteoarthritis in a Population from Northern Mexico-A Case-Control Study.

    abstract:BACKGROUND:Previous studies have found an association between the SNP rs143383 + 104T/C in the growth differentiation factor 5 (GDF5) gene and the risk of developing knee osteoarthritis (KOA) in various populations worldwide. OBJECTIVE:To discover if there is an association between the SNP rs143383 + 104T/C, in the GD...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2018.0142

    authors: García-Alvarado F,Rosales-González M,Arellano-Pérez-Vertti D,Espino-Silva P,Meza-Velazquez M,Ruiz-Flores P

    更新日期:2018-08-01 00:00:00

  • PARP-1 Overexpression as an Independent Prognostic Factor in Adult Non-M3 Acute Myeloid Leukemia.

    abstract:AIMS:Poly (ADP-ribose) polymerase-1 (PARP-1) plays an important role in the repair of damaged DNA and has prognostic significance in a variety of human malignancies. However, little is known about its expression levels and clinical implication in patients with acute myeloid leukemia (AML). MATERIALS AND METHODS:Quanti...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2018.0085

    authors: Pashaiefar H,Yaghmaie M,Tavakkoly-Bazzaz J,Ghaffari SH,Alimoghaddam K,Momeny M,Izadi P,Izadifard M,Kasaeian A,Ghavamzadeh A

    更新日期:2018-06-01 00:00:00

  • Low Expression of Long Noncoding RNA IRAIN Is Associated with Poor Prognosis in Non-M3 Acute Myeloid Leukemia Patients.

    abstract:AIMS:Deregulation of the long noncoding RNA IRAIN has been identified in several cancers. However, the expression pattern of IRAIN and its clinical implication in acute myeloid leukemia (AML) are unknown. The purpose of this study was to investigate the expression status of IRAIN and its clinical significance in non-M3...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2017.0281

    authors: Pashaiefar H,Izadifard M,Yaghmaie M,Montazeri M,Gheisari E,Ahmadvand M,Momeny M,Ghaffari SH,Kasaeian A,Alimoghaddam K,Ghavamzadeh A

    更新日期:2018-05-01 00:00:00

  • Identification of a Novel Nonsense ASPM Mutation in a Large Consanguineous Pakistani Family Using Targeted Next-Generation Sequencing.

    abstract:AIMS:To identify the pathogenic mutation underlying microcephaly primary hereditary (MCPH) in a large consanguineous Pakistani family. METHODS:A five-generation family with an autosomal recessive transmission of MCPH was recruited. Targeted next-generation DNA sequencing was carried out to analyze the genomic DNA samp...

    journal_title:Genetic testing and molecular biomarkers

    pub_type: 杂志文章

    doi:10.1089/gtmb.2017.0229

    authors: Khan A,Wang R,Han S,Ahmad W,Zhang X

    更新日期:2018-03-01 00:00:00

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