听力与言语-语言病理学

行为科学

医学伦理学

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  • mTOR-driven neural circuit changes initiate an epileptogenic cascade.

    abstract::Mutations in genes regulating mTOR pathway signaling are now recognized as a significant cause of epilepsy. Interestingly, these mTORopathies are often caused by somatic mutations, affecting variable numbers of neurons. To better understand how this variability affects disease phenotype, we developed a mouse model in ...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.pneurobio.2020.101974

    authors: LaSarge CL,Pun RYK,Gu Z,Riccetti MR,Namboodiri DV,Tiwari D,Gross C,Danzer SC

    更新日期:2020-12-09 00:00:00

  • The art of lineage tracing: From worm to human.

    abstract::Reconstructing the genealogy of every cell that makes up an organism remains a long-standing challenge in developmental biology. Besides its relevance for understanding the mechanisms underlying normal and pathological development, resolving the lineage origin of cell types will be crucial to create these types on-dem...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2020.101966

    authors: Garcia-Marques J,Espinosa-Medina I,Lee T

    更新日期:2020-11-26 00:00:00

  • Neuronal and astroglial monocarboxylate transporters play key but distinct roles in hippocampus-dependent learning and memory formation.

    abstract::Brain lactate formation, intercellular exchange and utilization has been implicated in memory formation. However, the individual role of either neuronal or astroglial monocarboxylate transporters for the acquisition and consolidation of information remains incomplete. Using novel transgenic mice and a viral vector app...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.pneurobio.2020.101888

    authors: Netzahualcoyotzi C,Pellerin L

    更新日期:2020-11-01 00:00:00

  • Hippocampal network dysfunction as a mechanism of early-onset dementia after preeclampsia and eclampsia.

    abstract::Preeclampsia is a hypertensive disorder of pregnancy that can involve dangerous neurological symptoms such as spontaneous seizures (eclampsia). Despite being diseases specific to the pregnant state, preeclampsia and eclampsia have long-lasting neurological consequences later in life, including changes in brain structu...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.pneurobio.2020.101938

    authors: Johnson AC,Li Z,Orfila JE,Herson PS,Cipolla MJ

    更新日期:2020-10-29 00:00:00

  • BDNF and Netrin-1 repression by C/EBPβ in the gut triggers Parkinson's disease pathologies, associated with constipation and motor dysfunctions.

    abstract::Chronic constipation is one of the most prominent prodromal symptoms in Parkinson's disease (PD), and Lewy bodies, enriched with aggregated α-Synuclein (α-Syn), propagation from the gut into the brain has been proposed to play a key role in PD etiopathogenesis. BDNF (Brain-derived neurotrophic factor) and Netrin-1 pro...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.pneurobio.2020.101905

    authors: Ahn EH,Kang SS,Liu X,Cao X,Choi SY,Musazzi L,Mehlen P,Ye K

    更新日期:2020-09-07 00:00:00

  • Using high spatial resolution fMRI to understand representation in the auditory network.

    abstract::Following rapid methodological advances, ultra-high field (UHF) functional and anatomical magnetic resonance imaging (MRI) has been repeatedly and successfully used for the investigation of the human auditory system in recent years. Here, we review this work and argue that UHF MRI is uniquely suited to shed light on h...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.pneurobio.2020.101887

    authors: Moerel M,Yacoub E,Gulban OF,Lage-Castellanos A,De Martino F

    更新日期:2020-08-01 00:00:00

  • Changes in human brain dynamics during behavioral priming and repetition suppression.

    abstract::Behavioral responses to a perceptual stimulus are typically faster with repeated exposure to the stimulus (behavioral priming). This implicit learning mechanism is critical for survival but impaired in a variety of neurological disorders, including Alzheimer's disease. Many studies of the neural bases for behavioral p...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.pneurobio.2020.101788

    authors: Korzeniewska A,Wang Y,Benz HL,Fifer MS,Collard M,Milsap G,Cervenka MC,Martin A,Gotts SJ,Crone NE

    更新日期:2020-06-01 00:00:00

  • Cysteine string proteins.

    abstract::Cysteine string protein (CSP) was discovered by use of a synapse-specific, monoclonal antibody to screen a cDNA expression library in Drosophila. A vertebrate CSP homolog was later identified and shown to co-purify with synaptic vesicles. CSP-α is now recognized as a membrane constituent of many regulated secretory or...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2020.101758

    authors: Gundersen CB

    更新日期:2020-05-01 00:00:00

  • White matter structure and myelin-related gene expression alterations with experience in adult rats.

    abstract::White matter (WM) plasticity during adulthood is a recently described phenomenon by which experience can shape brain structure. It has been observed in humans using diffusion tensor imaging (DTI) and myelination has been suggested as a possible mechanism. Here, we set out to identify molecular and cellular changes ass...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章

    doi:10.1016/j.pneurobio.2020.101770

    authors: Sampaio-Baptista C,Vallès A,Khrapitchev AA,Akkermans G,Winkler AM,Foxley S,Sibson NR,Roberts M,Miller K,Diamond ME,Martens GJM,De Weerd P,Johansen-Berg H

    更新日期:2020-04-01 00:00:00

  • Small cells with big implications: Microglia and sex differences in brain development, plasticity and behavioral health.

    abstract::Brain sex differences are programmed largely by sex hormone secretions and direct sex chromosome effects in early life, and are subsequently modulated by early life experiences. The brain's resident immune cells, called microglia, actively contribute to brain development. Recent research has shown that microglia are s...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2018.09.002

    authors: Nelson LH,Saulsbery AI,Lenz KM

    更新日期:2019-05-01 00:00:00

  • Effects of estrogens and androgens on mitochondria under normal and pathological conditions.

    abstract::Several lines of evidence have suggested that mitochondrial dysfunction plays a key role in neurodegeneration. The mitochondrial function is a potential target for steroid hormones, which could exert protective activities in the brain and other tissues. The decrease of some sex steroids with aging has been associated ...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2019.03.001

    authors: Mohajeri M,Martín-Jiménez C,Barreto GE,Sahebkar A

    更新日期:2019-05-01 00:00:00

  • Exercise as a therapeutic intervention for motor and non-motor symptoms in Parkinson's disease: Evidence from rodent models.

    abstract::Parkinson's disease (PD) is characterised by degeneration of dopaminergic neurons of the nigrostriatal pathway, which leads to the cardinal motor symptoms of the disease - tremor, rigidity and postural instability. A number of non-motor symptoms are also associated with PD, including cognitive impairment, mood disturb...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2018.11.003

    authors: Crowley EK,Nolan YM,Sullivan AM

    更新日期:2019-01-01 00:00:00

  • The role of neuro-epithelial-like and radial-glial stem and progenitor cells in development, plasticity, and repair.

    abstract::Neural stem and progenitor cells (NSPCs) are the primary source of new neurons in the brain and serve critical roles in tissue homeostasis and plasticity throughout life. Within the vertebrate brain, NSPCs are located within distinct neurogenic niches differing in their location, cellular composition, and proliferativ...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2018.06.004

    authors: Lindsey BW,Hall ZJ,Heuzé A,Joly JS,Tropepe V,Kaslin J

    更新日期:2018-11-01 00:00:00

  • The role of T cells in the pathogenesis of Parkinson's disease.

    abstract::Recent evidence has shown that neuroinflammation plays a key role in the pathogenesis of Parkinson's disease (PD). However, different components of the brain's immune system may exert diverse effects on neuroinflammatory events in PD. The adaptive immune response, especially the T cell response, can trigger type 1 pro...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2018.08.002

    authors: Chen Z,Chen S,Liu J

    更新日期:2018-10-01 00:00:00

  • Pluripotent stem cell-based therapy for Parkinson's disease: Current status and future prospects.

    abstract::Parkinson's disease (PD) is one of the most common neurodegenerative disorders, which affects about 0.3% of the general population. As the population in the developed world ages, this creates an escalating burden on society both in economic terms and in quality of life for these patients and for the families that supp...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2018.04.005

    authors: Sonntag KC,Song B,Lee N,Jung JH,Cha Y,Leblanc P,Neff C,Kong SW,Carter BS,Schweitzer J,Kim KS

    更新日期:2018-09-01 00:00:00

  • KCC2, epileptiform synchronization, and epileptic disorders.

    abstract::The K+-Cl- co-transporter KCC2 is a neuron-specific, Cl- extruder that uses K+ gradient for maintaining low intracellular [Cl-]. It is indeed well established that sustaining an outwardly-directed electrochemical Cl- gradient across the neuronal membrane is fundamental for a proper function of postsynaptic GABAA recep...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2017.11.002

    authors: Di Cristo G,Awad PN,Hamidi S,Avoli M

    更新日期:2018-03-01 00:00:00

  • Nano- and neurotoxicology: An emerging discipline.

    abstract::The present critical review analyzes the question of how nanoparticles from continuously growing industrial production and use of nanomaterials may impact human brain health. Available evidence suggests incomplete effectiveness of protective barriers of the brain against nanoparticles translocation to the brain. This ...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2017.10.003

    authors: Bencsik A,Lestaevel P,Guseva Canu I

    更新日期:2018-01-01 00:00:00

  • And yet it moves: Recovery of volitional control after spinal cord injury.

    abstract::Preclinical and clinical neurophysiological and neurorehabilitation research has generated rather surprising levels of recovery of volitional sensory-motor function in persons with chronic motor paralysis following a spinal cord injury. The key factor in this recovery is largely activity-dependent plasticity of spinal...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2017.10.004

    authors: Taccola G,Sayenko D,Gad P,Gerasimenko Y,Edgerton VR

    更新日期:2018-01-01 00:00:00

  • Modelling iron mismanagement in neurodegenerative disease in vitro: paradigms, pitfalls, possibilities & practical considerations.

    abstract::Although aberrant metabolism and deposition of iron has been associated with aging and neurodegeneration, the contribution of iron to neuropathology is unclear. Well-designed model systems that are suited to studying the putative pathological effect of iron are likely to be essential if such unresolved details are to ...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2017.08.004

    authors: Healy S,McMahon JM,FitzGerald U

    更新日期:2017-11-01 00:00:00

  • The application of information theory for the research of aging and aging-related diseases.

    abstract::This article reviews the application of information-theoretical analysis, employing measures of entropy and mutual information, for the study of aging and aging-related diseases. The research of aging and aging-related diseases is particularly suitable for the application of information theory methods, as aging proces...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2016.03.005

    authors: Blokh D,Stambler I

    更新日期:2017-10-01 00:00:00

  • Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots.

    abstract::Brain has exceptional high requirement for energy metabolism with glucose as the exclusive energy source. Decrease of brain energy metabolism and glucose uptake has been found in patients of Alzheimer's, Parkinson's and other neurodegenerative diseases, providing a clear link between neurodegenerative disorders and en...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2015.10.005

    authors: Yang SH,Li W,Sumien N,Forster M,Simpkins JW,Liu R

    更新日期:2017-10-01 00:00:00

  • Astrocyte elevated gene-1 (AEG-1) and the A(E)Ging HIV/AIDS-HAND.

    abstract::Recent attempts to analyze human immunodeficiency virus (HIV)-1-induced gene expression changes in astrocytes uncovered a multifunctional oncogene, astrocyte elevated gene-1 (AEG-1). Our previous studies revealed that AEG-1 regulates reactive astrocytes proliferation, migration and inflammation, hallmarks of aging and...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2016.03.006

    authors: Vartak-Sharma N,Nooka S,Ghorpade A

    更新日期:2017-10-01 00:00:00

  • Stem cell transplantation therapy for multifaceted therapeutic benefits after stroke.

    abstract::One of the exciting advances in modern medicine and life science is cell-based neurovascular regeneration of damaged brain tissues and repair of neuronal structures. The progress in stem cell biology and creation of adult induced pluripotent stem (iPS) cells has significantly improved basic and pre-clinical research i...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2017.03.003

    authors: Wei L,Wei ZZ,Jiang MQ,Mohamad O,Yu SP

    更新日期:2017-10-01 00:00:00

  • Anesthesia, brain changes, and behavior: Insights from neural systems biology.

    abstract::Long-term consequences of anesthetic exposure in humans are not well understood. It is possible that alterations in brain function occur beyond the initial anesthetic administration. Research in children and adults has reported cognitive and/or behavioral changes after surgery and general anesthesia that may be short ...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2017.01.005

    authors: Colon E,Bittner EA,Kussman B,McCann ME,Soriano S,Borsook D

    更新日期:2017-06-01 00:00:00

  • Synaptopathic mechanisms of neurodegeneration and dementia: Insights from Huntington's disease.

    abstract::Dementia encapsulates a set of symptoms that include loss of mental abilities such as memory, problem solving or language, and reduces a person's ability to perform daily activities. Alzheimer's disease is the most common form of dementia, however dementia can also occur in other neurological disorders such as Hunting...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2017.03.008

    authors: Tyebji S,Hannan AJ

    更新日期:2017-06-01 00:00:00

  • Adaptive and maladaptive neural compensatory consequences of sensory deprivation-From a phantom percept perspective.

    abstract::It is suggested that the brain undergoes plastic changes in order to adapt to changing environmental needs. Sensory deprivation results in decreased input to the brain leading to adaptive or maladaptive changes. Although several theories hypothesize the mechanism of these adaptive and maladaptive changes, the course o...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2017.03.010

    authors: Mohan A,Vanneste S

    更新日期:2017-06-01 00:00:00

  • Challenges in the development of therapeutics for narcolepsy.

    abstract::Narcolepsy is a neurological disorder that afflicts 1 in 2000 individuals and is characterized by excessive daytime sleepiness and cataplexy-a sudden loss of muscle tone triggered by positive emotions. Features of narcolepsy include dysregulation of arousal state boundaries as well as autonomic and metabolic disturban...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2015.12.002

    authors: Black SW,Yamanaka A,Kilduff TS

    更新日期:2017-05-01 00:00:00

  • Deep brain stimulation of the subthalamic nucleus in Parkinson's disease: From history to the interaction with the monoaminergic systems.

    abstract::Parkinson's disease is the second most common neurodegenerative disorder, characterized by the manifestation of motor symptoms, which are mainly attributed to the degeneration of dopamine neurons in the pars compacta of substantia nigra. Based on advancements in the understanding of the pathophysiology of the disease,...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2016.07.003

    authors: Faggiani E,Benazzouz A

    更新日期:2017-04-01 00:00:00

  • Interaction of language, auditory and memory brain networks in auditory verbal hallucinations.

    abstract::Auditory verbal hallucinations (AVH) occur in psychotic disorders, but also as a symptom of other conditions and even in healthy people. Several current theories on the origin of AVH converge, with neuroimaging studies suggesting that the language, auditory and memory/limbic networks are of particular relevance. Howev...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2016.11.002

    authors: Ćurčić-Blake B,Ford JM,Hubl D,Orlov ND,Sommer IE,Waters F,Allen P,Jardri R,Woodruff PW,David O,Mulert C,Woodward TS,Aleman A

    更新日期:2017-01-01 00:00:00

  • Alzheimer's disease due to loss of function: A new synthesis of the available data.

    abstract::Alzheimer's Disease (AD) is a highly complex disease involving a broad range of clinical, cellular, and biochemical manifestations that are currently not understood in combination. This has led to many views of AD, e.g. the amyloid, tau, presenilin, oxidative stress, and metal hypotheses. The amyloid hypothesis has do...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.pneurobio.2016.06.004

    authors: Kepp KP

    更新日期:2016-08-01 00:00:00

  • Polypharmacology of dopamine receptor ligands.

    abstract::Most neurological diseases have a multifactorial nature and the number of molecular mechanisms discovered as underpinning these diseases is continuously evolving. The old concept of developing selective agents for a single target does not fit with the medical need of most neurological diseases. The development of desi...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2016.03.011

    authors: Butini S,Nikolic K,Kassel S,Brückmann H,Filipic S,Agbaba D,Gemma S,Brogi S,Brindisi M,Campiani G,Stark H

    更新日期:2016-07-01 00:00:00

  • ALS: A bucket of genes, environment, metabolism and unknown ingredients.

    abstract::The scientific scenario of amyotrophic lateral sclerosis (ALS) has dramatically changed since TDP-43 aggregates were discovered in 2006 as the main component of the neuronal inclusions seen in the disease, and more recently, when the implication of C9ORF72 expansion in familial and sporadic cases of ALS and frontotemp...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2016.05.004

    authors: Zufiría M,Gil-Bea FJ,Fernández-Torrón R,Poza JJ,Muñoz-Blanco JL,Rojas-García R,Riancho J,López de Munain A

    更新日期:2016-07-01 00:00:00

  • Behavior, neuropsychology and fMRI.

    abstract::Cognitive neuroscientists in the late 20th century began the task of identifying the part(s) of the brain concerned with normal behavior as manifest in the psychological capacities as affective powers, reasoning, behaving purposively and the pursuit of goals, following introduction of the 'functional magnetic resonanc...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2016.07.001

    authors: Bennett MR,Hatton S,Hermens DF,Lagopoulos J

    更新日期:2016-01-01 00:00:00

  • The functional organization of motor nerve terminals.

    abstract::Neuromuscular junctions (NMJs) have long been studied as particularly accessible examples of chemical synapses. Nonetheless, some important features of neuromuscular transmission are still poorly understood. One of these is the low statistical variability of the number of transmitter quanta released from motor nerve t...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2015.09.004

    authors: Slater CR

    更新日期:2015-11-01 00:00:00

  • Multiple functions of neuronal plasma membrane neurotransmitter transporters.

    abstract::Removal from receptors of neurotransmitters just released into synapses is one of the major steps in neurotransmission. Transporters situated on the plasma membrane of nerve endings and glial cells perform the process of neurotransmitter (re)uptake. Because the density of transporters in the membranes can fluctuate, t...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2015.08.002

    authors: Raiteri L,Raiteri M

    更新日期:2015-11-01 00:00:00

  • The ventral pallidum: Subregion-specific functional anatomy and roles in motivated behaviors.

    abstract::The ventral pallidum (VP) plays a critical role in the processing and execution of motivated behaviors. Yet this brain region is often overlooked in published discussions of the neurobiology of mental health (e.g., addiction, depression). This contributes to a gap in understanding the neurobiological mechanisms of psy...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2015.03.005

    authors: Root DH,Melendez RI,Zaborszky L,Napier TC

    更新日期:2015-07-01 00:00:00

  • Neuronal stathmins: a family of phosphoproteins cooperating for neuronal development, plasticity and regeneration.

    abstract::Nervous system development, plasticity and regeneration require numerous, coordinated and finely tuned subcellular mechanisms. Phosphoproteins of the stathmin family, originally identified as intracellular signal relay proteins, are mostly or exclusively expressed in the nervous system with a high level of expression ...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2014.09.002

    authors: Chauvin S,Sobel A

    更新日期:2015-03-01 00:00:00

  • Action control processes in autism spectrum disorder--insights from a neurobiological and neuroanatomical perspective.

    abstract::Autism spectrum disorders (ASDs) encompass a range of syndromes that are characterized by social interaction impairments, verbal and nonverbal communication difficulties, and stereotypic or repetitive behaviours. Although there has been considerable progress in understanding the mechanisms underlying the changes in th...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2014.11.002

    authors: Chmielewski WX,Beste C

    更新日期:2015-01-01 00:00:00

  • Brain alterations in paedophilia: a critical review.

    abstract::Psychosocial and biological factors have been implicated in paedophilia, such as alterations in brain structure and function. The purpose of this paper is to review the expanding body of literature on this topic including brain abnormality case reports, as well as structural and functional neuroimaging studies. Case s...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2014.07.005

    authors: Mohnke S,Müller S,Amelung T,Krüger TH,Ponseti J,Schiffer B,Walter M,Beier KM,Walter H

    更新日期:2014-11-01 00:00:00

  • Metabolism and functions of copper in brain.

    abstract::Copper is an important trace element that is required for essential enzymes. However, due to its redox activity, copper can also lead to the generation of toxic reactive oxygen species. Therefore, cellular uptake, storage as well as export of copper have to be tightly regulated in order to guarantee sufficient copper ...

    journal_title:Progress in neurobiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pneurobio.2014.01.002

    authors: Scheiber IF,Mercer JF,Dringen R

    更新日期:2014-05-01 00:00:00

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