Prolactin bioassay and hyperprolactinemia.

abstract：:The 1865 volume of the "II Morgagni", one of the most important Italian medical journals of the 19th century, presented two important articles, milestones for further scientific studies in the field of sexual differentiation. One was the original description of the "ramified cells" of testicular tubules by E. Sertoli,...

journal_title：Journal of endocrinological investigation

authors： Virdis R

更新日期：2005-11-01 00:00:00

abstract：:Endemic goiter in Morocco is localized in the Rif and Atlas mountains. In this study, performed in the Skoura-Toundoute areas (high Atlas), we demonstrate that iodine deficiency is the main factor involved in the development of endemic goiter. However it may not constitute the only etiological factor. The median urina...

journal_title：Journal of endocrinological investigation

authors： Aquaron R,Zarrouck K,el Jarari M,Ababou R,Talibi A,Ardissone JP

更新日期：1993-01-01 00:00:00

abstract：:This study examined the association of depression, anxiety, and stress with Type 2 diabetes (T2DM) in Bahrain, an island-country with a very high prevalence of T2DM. This was a cross-sectional study involving administering Depression Anxiety Stress Scales (DASS)-21 structured depression, anxiety, and stress scale to 1...

journal_title：Journal of endocrinological investigation

authors： Almawi W,Tamim H,Al-Sayed N,Arekat MR,Al-Khateeb GM,Baqer A,Tutanji H,Kamel C

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:The coexistence of insulin and ACTH hypersecretion in the same patient is extremely rare. A diabetic patient with a pancreatic endocrine tumor (PET) co-secreting insulin and ACTH is even rarer and has never been described. The combination of these two endocrine syndromes results in a peculiar clinical pictur...

journal_title：Journal of endocrinological investigation

authors： Filippella M,Davì MV,Doveri G,Lillaz E,Ciccarelli A,Massimetti E,Toaiari M,Falconi M,Colao A,Faggiano A

更新日期：2011-03-01 00:00:00

abstract：:Six-day treatment of neonatal rats with T3 or T4 resulted in a considerable depression of T4 production in response to exogenous TSH in adulthood. This supports the hypothetical conclusion that hormonal imprinting, i.e. the presence of the hormone and its interaction with the cell during the period of receptor maturat...

journal_title：Journal of endocrinological investigation

authors： Csaba G,Nagy SU

更新日期：1985-12-01 00:00:00

abstract：PURPOSE:To report the long-term effectiveness and safety of the recombinant human growth hormone Omnitrope®, a somatropin biosimilar to Genotropin®, in Italian patients with growth hormone deficiency (GHD) enrolled in the PATRO Adults study. METHODS:The PATRO Adults study is an ongoing observational, longitudinal, non...

journal_title：Journal of endocrinological investigation

authors： Ferone D,Profka E,Gasco V,Ambrosio MR,Colao A,Di Somma C,Puxeddu E,Arnaldi G,Pagano C,Zecchi E,Pietropoli A,Beck-Peccoz P

更新日期：2017-06-01 00:00:00

abstract：:Circulating TSH bioactivity may vary in several clinical and experimental conditions. Since the reliability of the current methods for the measurement of TSH bioactivity is limited, a new bioassay based on cAMP accumulation in Chinese Hamster Ovary cells transfected with recombinant human TSH receptor (CHO-R) was set ...

journal_title：Journal of endocrinological investigation

authors： Persani L,Tonacchera M,Beck-Peccoz P,Vitti P,Mammoli C,Chiovato L,Elisei R,Faglia G,Ludgate M,Vassart G

更新日期：1993-07-01 00:00:00

abstract：:Vitamin D via its receptor has essential actions on parathyroid cells, inhibiting PTH secretion, and parathyroid cell proliferation. While the effects of vitamin D depletion in the pathogenesis of secondary hyperparathyroidism in elderly individuals or in the occurrence of parathyroid hyperplasia in patients with rena...

journal_title：Journal of endocrinological investigation

authors： Nuti R,Merlotti D,Gennari L

更新日期：2011-07-01 00:00:00

abstract：:Central hypothyroidism (CH) is a rare cause of hypothyroidism characterized by a defect of thyroid hormone production due to an insufficient TSH stimulation. CH can be congenital in the case of genetic defects or acquired in the case of lesions affecting either pituitary or hypothalamus. Diagnosis is usually made on a...

journal_title：Journal of endocrinological investigation

authors： Lania A,Giavoli C,Ferrante E,Beck-Peccoz P

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Results of circulating Ghrelin levels in hyper- or hypothyroidism are conflicting and only overt thyroid dysfunction has been evaluated. AIM:To evaluate in a large number of patients with thyroid disfunction whether: a) hyper- and hypothyroidism (clinical or subclinical) are associated with variations in bo...

journal_title：Journal of endocrinological investigation

authors： Tanda ML,Lombardi V,Genovesi M,Ultimieri F,Lai A,Gandolfo M,Dalle Mule I,Grasso L,Bogazzi F,Broglio F,Ghigo E,Martino E,Bartalena L

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The aim of the study was to evaluate diurnal blood pressure (BP) profiles in patients with primary aldosteronism and to compare them to those in subjects with essential hypertension. The effects of specific therapy on the circadian BP profiles have been studied. MATERIALS AND METHODS:Sixty-four patients wit...

journal_title：Journal of endocrinological investigation

authors： Zacharieva S,Orbetzova M,Elenkova A,Stoynev A,Yaneva M,Schigarminova R,Kalinov K,Nachev E

更新日期：2006-01-01 00:00:00

abstract：:Leptin, insulin, ghrelin, and IGF-I are circulating peptide hormones concerned with energy homeostasis and the regulation of GH axis. They are present in human milk, and are thought to promote neonatal development. The aim of the present study was to detect these substances in goat milk and determine whether their lev...

journal_title：Journal of endocrinological investigation

authors： Rosi F,Aufy AA,Magistrelli D

更新日期：2009-06-01 00:00:00

abstract：:The multiple effects of vitamin D on skeletal and extra-skeletal tissues increased the attention of scientists and public to the possible relationship between hypovitaminosis D and a variety of acute and chronic diseases. However, several points are still largely debated. In particular, the definition of optimal vitam...

journal_title：Journal of endocrinological investigation

authors： Romagnoli E,Carnevale V,Biondi P,Minisola S

更新日期：2014-07-01 00:00:00

abstract：CONTEXT:The latest guidelines of the 4th International Workshop on Asymptomatic Primary Hyperparathyroidism (aPHPT) reintroduced hypercalciuria (i.e. urinary calcium > 400 mg/day) as criterion for surgery. However, the value of hypercalciuria as a predictor of nephrolithiasis and the correct cut-off values still need t...

journal_title：Journal of endocrinological investigation

authors： Saponaro F,Cetani F,Mazoni L,Apicella M,Di Giulio M,Carlucci F,Scalese M,Pardi E,Borsari S,Bilezikian JP,Marcocci C

更新日期：2020-05-01 00:00:00

abstract：:The prevalence of primary aldosteronism has increased since many patients who were previously considered as being affected by low renin essential hypertension are actually satisfying the new diagnostic criteria using plasma aldosterone/ plasma renin activity (PRA) ratio. Many of these cases could be classified as subc...

journal_title：Journal of endocrinological investigation

authors： Armanini D,Fiore C

更新日期：2009-07-01 00:00:00

abstract：:Neurological disorders, such as seizures, are not infrequently associated with anti-leukemic therapy. It has been hypothesized that a disrupted peptidergic transmission between neurons could be the cellular basis of the neurological dysfunction. Since endogenous opioids have been recently found to alter neuronal funct...

journal_title：Journal of endocrinological investigation

authors： Iannetti P,Fabbri A,Meloni G,Moleti ML,Ulisse S,Mandelli F,Isidori A,Imperato C

更新日期：1989-10-01 00:00:00

abstract：:Obesity and insulin resistance are common features of Type 2 Diabetes. A new protein called resistin has been shown to be secreted by adipocytes in mice and to influence insulin sensitivity. The goal of the present study was to investigate the associations between one polymorphism (g-420C>G) of the human resistin gene...

journal_title：Journal of endocrinological investigation

authors： Bouchard L,Weisnagel SJ,Engert JC,Hudson TJ,Bouchard C,Vohl MC,Pérusse L

更新日期：2004-12-01 00:00:00

abstract：PURPOSE:Leptin is associated with cardiovascular risk factors (e.g. hypertension, insulin resistance, kidney disease and excess body weight). Experimental studies showed that leptin might affect serum uric acid, by modulation of the uric acid excretion. However, there are few observational data on the relationship betw...

journal_title：Journal of endocrinological investigation

authors： D'Elia L,Giaquinto A,Cappuccio FP,Iacone R,Russo O,Strazzullo P,Galletti F

更新日期：2020-05-01 00:00:00

abstract：:The research suggests that adiponectin plays an important role in sensitizing insulin action. It is interesting to find that the lower levels of adiponectin exist in the plasma of obese and Type 2 diabetes subjects and in the adipose tissue of obese, db/db mice, and insulin-resistant individuals. However, the underlyi...

journal_title：Journal of endocrinological investigation

authors： Sun S,Liu Y,Lu J,Omar A,Sun S,Bi Y,Wang C

更新日期：2011-01-01 00:00:00

abstract：:The IGFs are ubiquitous and have pleoitropic effects. They are critical for normal growth and development, and for normal functioning of adult tissues. A liver-specific gene-deletion knockout of the IGF-I gene resulted in a mouse model with reduced circulating IGF-I levels, that led to insulin resistance due to the se...

journal_title：Journal of endocrinological investigation

authors： Yakar S,Pennisi P,Kim CH,Zhao H,Toyoshima Y,Gavrilova O,LeRoith D

更新日期：2005-01-01 00:00:00

abstract：UNLABELLED:ABSTRACT. Several data show that meal intake and nutritional status regulate circulating ghrelin concentrations in humans. Ghrelin mainly circulates in two different forms: octanoyl and des-octanoyl ghrelin. Most circulating ghrelin is des-octanoyl ghrelin which is considered inactive because it lacks endocr...

journal_title：Journal of endocrinological investigation

authors： Lucidi P,Murdolo G,Di Loreto C,Parlanti N,De Cicco A,Ranchelli A,Fatone C,Taglioni C,Fanelli C,Santeusanio F,De Feo P

更新日期：2004-05-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the prevalence and risk factors associated with female sexual dysfunction (FSD) in young women with type 1 diabetes treated with different intensive insulin regimens. METHODS:Type 1 diabetic women aged 18-35 years were included in this study if they had stable couple relat...

journal_title：Journal of endocrinological investigation

authors： Maiorino MI,Bellastella G,Castaldo F,Petrizzo M,Giugliano D,Esposito K

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:Elimination of thyroid antigens by total thyroid ablation (TTA), namely, thyroidectomy followed by radioiodine, may be beneficial for Graves' Orbitopathy (GO). TTA is usually performed with a 131I dose of 30 mCi. In Italy, this dose must be followed by a 24-h protected hospitalization, with increase in the wa...

journal_title：Journal of endocrinological investigation

authors： Leo M,Sabini E,Ionni I,Sframeli A,Mazzi B,Menconi F,Molinaro E,Bianchi F,Brozzi F,Santini P,Elisei R,Nardi M,Vitti P,Marcocci C,Marinò M

更新日期：2018-03-01 00:00:00

abstract：:Aim of the study was to compare urinary galactosyl-hydroxylysine (GHyl), deoxypyridinoline (D-Pyr) and pyridinoline (Pyr) before and after 5 to 9 months of hormone replacement therapy (HRT) in postmenopausal women. The urinary markers were measured by HPLC in the second void of fasting samples and were expressed as ra...

journal_title：Journal of endocrinological investigation

authors： Marabini R,Sirtori P,Chionna R,Barzizza L,Rubinacci A

更新日期：1996-03-01 00:00:00

abstract：:The AA. studied the glycometabolic activity of prazosin, a hypotensive drug with an adrenergic blocking activity of alpha-1-selective type. Twenty-two moderately hypertensive subjects were studied. Their ages ranged from 37 to 57 years; 10 of the patients had non-insulin dependent diabetes mellitus. After overnight fa...

journal_title：Journal of endocrinological investigation

authors： Ferlito S,Puleo F,Carrà G,Damante G,Di Vincenzo S,Del Campo F

更新日期：1983-06-01 00:00:00

abstract：:In addition to growth hormone (GH), sex hormones are important determinants of body composition. Aging is accompanied by a decrease in free testosterone levels and, as BMI as well as fat mass increase with age (with a redistribution of body fat), whereas muscle mass decreases, it is tempting to attribute a causal role...

journal_title：Journal of endocrinological investigation

authors： Vermeulen A,Goemaere S,Kaufman JM

更新日期：1999-01-01 00:00:00

abstract：:The association of several risk factors, obesity, dyslipoproteinemia, hepatic steatosis, insulin resistance and hypertension with Type 2 (non-insulin-dependent) diabetes mellitus and myocardial infarction has long been known and has been termed the "metabolic syndrome". In 1988 Reaven introduced syndrome X as the link...

journal_title：Journal of endocrinological investigation

authors： Johannsson G,Bengtsson BA

更新日期：1999-01-01 00:00:00

abstract：:The DAZ (deleted in azoospermia) gene family is considered the major AZFc ("azoospermia factor" c) candidate responsible for male infertility. However, other genes have been recently mapped to this region and they could contribute to the AZFc phenotype. In particular, the testis-specific CDY1 (chromadomain protein 1) ...

journal_title：Journal of endocrinological investigation

authors： Ferlin A,Moro E,Rossi A,Foresta C

更新日期：2001-02-01 00:00:00

abstract：PURPOSE:Although men with spinal cord injury (SCI) exhibit a prostate volume significantly smaller compared to age-matched able-bodied men, the independent association of lower prostate volume with its putative determinants has never been analyzed in this population. This study was designed to identify variables indepe...

journal_title：Journal of endocrinological investigation

authors： D'Andrea S,Castellini C,Minaldi E,Totaro M,Felzani G,Francavilla S,Francavilla F,Barbonetti A

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:Testosterone replacement therapy (TRT) is recommended for the treatment of most cases of male hypogonadism. Transdermal testosterone (T) gels are commonly used in clinical practice; however, there is little evidence concerning how to monitor dosage to bring and maintain serum T levels in the normal physiologic ...

journal_title：Journal of endocrinological investigation

authors： Sansone A,Sansone M,Selleri R,Schiavo A,Gianfrilli D,Pozza C,Zitzmann M,Lenzi A,Romanelli F

更新日期：2019-12-01 00:00:00