Bone turnover is reduced in children with juvenile rheumatoid arthritis.

abstract：:In order to precise the relationships between TSH, FT3, and FT4 nycthemeral variations and the relationships between thyroid hormone variations and sleep, 8 healthy young males were studied twice, once during a 24-h experiment with normal nocturnal sleep, and once during a night of sleep deprivation. The subjects rece...

journal_title：Journal of endocrinological investigation

authors： Goichot B,Brandenberger G,Saini J,Wittersheim G,Follenius M

更新日期：1994-03-01 00:00:00

abstract：:Excess production of proopiomelanocortin (POMC)-derived peptides with aldosterone-stimulating activity has been suggested to play a pathogenetic role in idiopathic hyperaldosteronism (IHA). To further investigate this issue, the opiate receptor antagonist naloxone was administered to 14 patients with primary aldostero...

journal_title：Journal of endocrinological investigation

authors： Fallo F,Boscaro M,Sonino N,Mantero F

更新日期：1988-04-01 00:00:00

abstract：:Plasma levels and 24-h urinary excretion of cyclic AMP and cyclic GMP were measured in 18 patients with hyperthyroidism, 7 patients with hypothyroidism and 25 normal subjects. Mean plasma and urinary levels of both cyclic AMP and cyclic GMP were significantly positive correlations between the serum thyroid hormone lev...

journal_title：Journal of endocrinological investigation

authors： Peracchi M,Bamonti-Catena F,Lombardi L,Reschini E,Toschi V,Maiolo AT,Polli EE

更新日期：1983-06-01 00:00:00

abstract：PURPOSE:To investigate the effects of metabolic abnormalities, hyperandrogenemia and ovulation induction by clomiphene/acupuncture on liver function parameters among women with polycystic ovary syndrome (PCOS). METHODS:This is a secondary analysis of a randomized controlled trial. All 1000 subjects were diagnosed as P...

journal_title：Journal of endocrinological investigation

authors： Cai WY,Gao JS,Luo X,Ma HL,Ge H,Liu N,Xia Q,Wang Y,Han BW,Wu XK

更新日期：2019-05-01 00:00:00

abstract：:Pyridinoline (Pyr) and deoxypyridinoline (D-Pyr) are two cross-links of collagen molecules, that are present in the extracellular matrix and released during its degradation. Pyr is present in bone and cartilage, but not in significant amounts in other connective tissues and D-Pyr appears to be specific for bone tissue...

journal_title：Journal of endocrinological investigation

authors： Calabresi E,Lasagni L,Franceschelli F,de Leonardis V,Becorpi A,Serio M,Brandi ML

更新日期：1994-09-01 00:00:00

abstract：:Reportedly, the responsiveness of somatotrope cells to GHRH is reduced in elderly humans but it is totally restored by arginine (ARG) which likely acts by inhibiting hypothalamic release of somatostatin. As this effect was observed after infusion of high doses of the amino acid, in this study, we compared the effect o...

journal_title：Journal of endocrinological investigation

authors： Ghigo E,Ceda GP,Valcavi R,Goffi S,Zini M,Mucci M,Valenti G,Cocchi D,Müller EE,Camanni F

更新日期：1994-02-01 00:00:00

abstract：:1-123 metaiodobenzylguanidine (1-123 MIBG) scintigraphy is known for its high specificity in detecting pheochromocytoma and other tumors of neural crest origin. In this rare case report, we describe a definite adrenocortical adenoma that demonstrated false-positive uptake at I-123 MIBG scintigraphy and a remarkable ac...

journal_title：Journal of endocrinological investigation

authors： Letizia C,De Toma G,Massa R,Corsi A,Caliumi C,Subioli S,D'Erasmo E

更新日期：1998-12-01 00:00:00

abstract：:The assessment of growth hormone (GH) secretory status is often difficult because of the intermittent nature of GH release and resulting wide swings in plasma GH levels. Urinary GH excretion holds promise as an index of integrated plasma GH free of this limitation, but technical problems have prevented its use until r...

journal_title：Journal of endocrinological investigation

authors： Winer LM,Shaw MA,Baumann G

更新日期：1989-07-01 00:00:00

abstract：:Finding that estrogen plays an important role in bone homeostasis in men prompted research on relationship of polymorphism at the CYP19 gene and the bone mass. Therefore, influence of 3-bp deletion/insertion polymorphism of CYP19 (TTTA)7 allele on the peak bone mass attainment in males was studied. Fifty-eight unrelat...

journal_title：Journal of endocrinological investigation

authors： Kastelan D,Grubic Z,Kraljevic I,Duric K,Kardum I,Dusek T,Stingl K,Giljevic Z,Kerhin-Brkljacic V,Suchanek E,Korsic M

更新日期：2007-06-01 00:00:00

abstract：:Basal IGF-I levels and the GH response to at least two among provocative stimuli such as clonidine (CLO, Catapresan, 150 mcg/m2 p.o.), GHRH (1 mcg/kg i.v.)+arginine (ARG, 0.5 g/kg i.v. infusion during 30 min) and GHRH+pyridostigmine (PD, Mestinon cpr 60 mg p.o.) have been evaluated in 43 children with Prader-Willi syn...

journal_title：Journal of endocrinological investigation

authors： Corrias A,Bellone J,Beccaria L,Bosio L,Trifirò G,Livieri C,Ragusa L,Salvatoni A,Andreo M,Ciampalini P,Tonini G,Crinò A

更新日期：2000-02-01 00:00:00

abstract：:Human amniotic fluid (HAF) contains multipotent stem cells [amniotic fluid-derived stem cells (AFSC)] which can differentiate into a variety of different cell types. Recently, we demonstrated that obestatin, a peptide encoded by the ghrelin gene, exerts anti-apoptotic effects in pancreatic beta-cells and human islets ...

journal_title：Journal of endocrinological investigation

authors： Trovato L,De Fazio R,Annunziata M,Sdei S,Favaro E,Ponti R,Marozio L,Ghigo E,Benedetto C,Granata R

更新日期：2009-12-01 00:00:00

abstract：:The prevalence of primary aldosteronism has increased since many patients who were previously considered as being affected by low renin essential hypertension are actually satisfying the new diagnostic criteria using plasma aldosterone/ plasma renin activity (PRA) ratio. Many of these cases could be classified as subc...

journal_title：Journal of endocrinological investigation

authors： Armanini D,Fiore C

更新日期：2009-07-01 00:00:00

abstract：:Dopamine agonists have been associated with increased risk of cardiac valve regurgitation in patients with Parkinson's disease. Whether these drugs might be harmful for patients with hyperprolactinemia is still unsettled. Occasional case reports and 7 studies on the relationship between cabergoline and cardiac valve r...

journal_title：Journal of endocrinological investigation

authors： Bogazzi F,Manetti L,Raffaelli V,Lombardi M,Rossi G,Martino E

更新日期：2008-12-01 00:00:00

abstract：:We describe a patient with Cushing's syndrome and metastatic small cell lung cancer. The plasma ACTH concentrations were markedly elevated (91.6 pmol/L), and the AM cortisol did not suppress by > 50% overnight after administration of 8 mg dexamethasone, both consistent with the ectopic ACTH syndrome. Immunohistochemic...

journal_title：Journal of endocrinological investigation

authors： Auchus RJ,Mastorakos G,Friedman TC,Chrousos GP

更新日期：1994-06-01 00:00:00

abstract：:The renin-angiotensin-aldosterone system (RAAS) plays a well-recognized role in the regulation of BP and in salt and water balance. Since hypertension affects a considerable proportion of obese patients, circulating RAAS has been studied in obese subjects with and without hypertension, albeit with conflicting results....

journal_title：Journal of endocrinological investigation

authors： Faloia E,Gatti C,Camilloni MA,Mariniello B,Sardu C,Garrapa GG,Mantero F,Giacchetti G

更新日期：2002-04-01 00:00:00

abstract：:Scavenger receptor A (SR-A) is the main receptor through which oxidized LDL (oxLDL) and advanced glycation end products get into the cells. The aim of the present study was to investigate the effect of an ACE inhibitor, perindopril, on the expression of SR-A in renal tubulointerstitium of diabetic rats. Diabetes was i...

journal_title：Journal of endocrinological investigation

authors： Sun L,Wen JH,Sun HL,Shu XC,Hu F,Yin DC,Yang Q,Zeng YJ,Sun Y,Liu L

更新日期：2012-05-01 00:00:00

abstract：:Recently, bromocriptine has been successfully introduced as medical therapy for the pituitary hypersecreting syndromes of hyperprolactinemia and acromegaly. Subsequently, an inhibitory effect on ACTH secretion was reported using bromocriptine in Cushing's disease. While most studies have focused on the acute response ...

journal_title：Journal of endocrinological investigation

authors： Kapcala LP,Jackson IM

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:Activation of the farnesoid X receptor (FXR), a member of the nuclear receptor steroid superfamily, leads to anti-inflammatory and anti-fibrotic effects in several tissues, including the lung. We have recently demonstrated a protective effect of the farnesoid X receptor (FXR) agonist obeticholic acid (OCA) i...

journal_title：Journal of endocrinological investigation

authors： Comeglio P,Filippi S,Sarchielli E,Morelli A,Cellai I,Corno C,Adorini L,Vannelli GB,Maggi M,Vignozzi L

更新日期：2019-08-01 00:00:00

abstract：:American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi, and European Thyroid Association medical guidelines for clinical practice for the diagnosis and management of thyroid nodules are systematically developed statements to assist health care professionals in medical decision making for ...

journal_title：Journal of endocrinological investigation

authors： Gharib H,Papini E,Paschke R,Duick DS,Valcavi R,Hegedüs L,Vitti P,AACE\/AME\/ETA Task Force on Thyroid Nodules.

更新日期：2010-01-01 00:00:00

abstract：:Final height was evaluated in 47 patients with classical 21-hydroxylase treated since diagnosis, and in 29 patients with nonclassical (NC) 21-hydroxylase deficiency who had never been treated before reaching final adult height. Classical patients achieved final heights consistently below the mean for the general popul...

journal_title：Journal of endocrinological investigation

authors： New MI,Gertner JM,Speiser PW,Del Balzo P

更新日期：1989-01-01 00:00:00

abstract：:GH response to an iv bolus of growth-hormone-releasing hormone (GHRH 1-44, 2 micrograms/kg iv) was evaluated in 17 prepubertal children with total GH deficiency (GHD), 6 with partial GHD and in 7 prepubertal normal but short children tested as control. GH response to conventional pharmacological (insulin and arginine ...

journal_title：Journal of endocrinological investigation

authors： Bozzola M,Tatò L,Cisternino M,Nava C,Valtorta A,Chiesa M,Severi F,Gaburro D

更新日期：1986-12-01 00:00:00

abstract：:A 45-year-old man presented with gynecomastia, hypertension and a large left adrenal mass. Further evaluation revealed elevated serum concentrations of estrogen, estrone sulfate, androstenedione, dehydroepiandrosterone, dehydroepiandrosterone sulfate, deoxycorticosterone, and aldosterone and increased 24-hour urinary ...

journal_title：Journal of endocrinological investigation

authors： Zayed A,Stock JL,Liepman MK,Wollin M,Longcope C

更新日期：1994-04-01 00:00:00

abstract：:We report here on the isolation and repertoire characterization of a Graves' thyroid T cell population which, unlike most Graves' thyroid T cell isolates reported before, was rich in CD4-CD8- T cells (16%, all TcR gamma delta+) and CD8+ T cells (75%) [TcR alpha beta+ (59%) and TcR gamma delta+ (16%)]. Only 7% of the i...

journal_title：Journal of endocrinological investigation

authors： Santamaria P,Lewis C,Barbosa JJ

更新日期：1993-12-01 00:00:00

abstract：:The pineal gland contains many peptides known to be implicated in melatonin production. We examined the effects of a synthetic pineal tetrapeptide Ala-Glu-Asp-Gly on melatonin secretion by the pineal gland. The tetrapeptide effects on pineal gland melatonin secretion were studied in young (9 weeks) and old (27 months)...

journal_title：Journal of endocrinological investigation

authors： Djeridane Y,Khavinson VKh,Anisimov VN,Touitou Y

更新日期：2003-03-01 00:00:00

abstract：:Follicular thyroid carcinoma may spread distant metastases in sites such as bone, lung and brain. In our series of 448 patients with follicular thyroid carcinoma, distant metastases were present in 25% of cases. We report here a case of follicular thyroid carcinoma with a single metastasis at the right adrenal gland, ...

journal_title：Journal of endocrinological investigation

authors： Girelli ME,Casara D,Rubello D,Piccolo M,Piotto A,Pelizzo MR,Busnardo B

更新日期：1993-02-01 00:00:00

abstract：:Severe vitamin D deficiency has been found to be prevalent in institutionalized elderly persons in several countries. The aim of the present work was to assess the vitamin D status of institutionalized elderly and compare it to that of community-living independent elderly in southern Greece during summer. Serum 25-hyd...

journal_title：Journal of endocrinological investigation

authors： Papapetrou PD,Triantafyllopoulou M,Korakovouni A

更新日期：2008-09-01 00:00:00

abstract：:Exhaustive graded exercise leads to changes of hormones, carbohydrate, and lipid metabolism in normal controls and obese patients after prolonged starvation. Concomitant with a large increase of plasma catecholamines, insulin concentration is reduced and blood glucose levels slowly increase. More glucose is made avail...

journal_title：Journal of endocrinological investigation

authors： Jakober B,Schmülling RM,Müller PH,Eggstein M

更新日期：1983-12-01 00:00:00

abstract：:According to recent studies showing the presence of estrogens receptors (ERs) in the human female lower urinary tract, we performed ER and progesterone receptor (PR) assays in fresh frozen and paraffin embedded biopsies taken from the urinary bladder. Fourteen females undergoing endoscopy during staging for gynecologi...

journal_title：Journal of endocrinological investigation

authors： Pacchioni D,Revelli A,Casetta G,Cassoni P,Piana P,Tizzani A,Bussolati G,Massobrio M

更新日期：1992-11-01 00:00:00

abstract：:Prolactin, growth hormone and thyroid stimulating hormone responses to thyrotropin releasing hormone (TRH) and metoclopramide were determined in 12 alcoholic men with biopsy proven liver disease and were compared to those of 8 age matched normal controls. All subjects were challenged with TRH (400 micrograms) and meto...

journal_title：Journal of endocrinological investigation

authors： Van Thiel DH,Gavaler JS,Sanghvi A

更新日期：1982-09-01 00:00:00

abstract：:We examined the distribution of nuclear T3 in mature rat brain with the aim of determining specific targets of thyroid hormones within this tissue. Saturation experiments, performed in 9 different structures of the brain and in 4 parts of the cortex, revealed the presence of a single class of binding sites with a mean...

journal_title：Journal of endocrinological investigation

authors： Ruel J,Faure R,Dussault JH

更新日期：1985-08-01 00:00:00