Bone density and risk of hip fracture in men and women: cross sectional analysis.

abstract：OBJECTIVE:To examine doctors' perspectives about their experiences with handheld computers in clinical practice. DESIGN:Qualitative study of eight focus groups consisting of doctors with diverse training and practice patterns. SETTING:Six practice settings across the United States and two additional focus group sessi...

journal_title：BMJ (Clinical research ed.)

authors： McAlearney AS,Schweikhart SB,Medow MA

更新日期：2004-05-15 00:00:00

abstract：OBJECTIVE:To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as an instrument to investigate the causal role of alcohol in cardiovascular disease. DESIGN:Mendelian randomisation meta-analysis of 56 epidemiological studies. PARTICIPANTS:261 991 individuals of European descent, including 20 259 c...

journal_title：BMJ (Clinical research ed.)

authors： Holmes MV,Dale CE,Zuccolo L,Silverwood RJ,Guo Y,Ye Z,Prieto-Merino D,Dehghan A,Trompet S,Wong A,Cavadino A,Drogan D,Padmanabhan S,Li S,Yesupriya A,Leusink M,Sundstrom J,Hubacek JA,Pikhart H,Swerdlow DI,Panayiotou

更新日期：2014-07-10 00:00:00

abstract：OBJECTIVE:To determine whether short-term, oral low dose prednisolone (< or = 15 mg daily) is superior to placebo and non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis. DESIGN:Meta-analysis of randomised trials of oral corticosteroids compared with placebo or a non-steroidal anti-inflammatory...

journal_title：BMJ (Clinical research ed.)

authors： Gøtzsche PC,Johansen HK

更新日期：1998-03-14 00:00:00

abstract：OBJECTIVE:To evaluate the effect of intensive geriatric rehabilitation on demented patients with hip fracture. DESIGN:Preplanned subanalysis of randomised intervention study. Settting: Jyväskylä Central Hospital, Finland. PARTICIPANTS:243 independently living patients aged 65 years or older admitted to hospital with ...

journal_title：BMJ (Clinical research ed.)

authors： Huusko TM,Karppi P,Avikainen V,Kautiainen H,Sulkava R

更新日期：2000-11-04 00:00:00

abstract：OBJECTIVE:To determine the relative importance of appropriate prescribing for asthma in explaining high rates of hospital admission for asthma among east London general practices. DESIGN:Poisson regression analysis describing relation of each general practice's admission rates for asthma with prescribing for asthma an...

journal_title：BMJ (Clinical research ed.)

authors： Griffiths C,Sturdy P,Naish J,Omar R,Dolan S,Feder G

更新日期：1997-02-15 00:00:00

abstract：OBJECTIVE:To describe the progression of HIV disease in a haemophilic cohort and to show the influence of treatment. DESIGN:11 year longitudinal clinical and laboratory study. SETTING:A haemophilia centre. PATIENTS:111 patients infected with HIV during October 1979 to July 1985. MAIN OUTCOME MEASURES:Symptoms of HI...

journal_title：BMJ (Clinical research ed.)

authors： Lee CA,Phillips AN,Elford J,Janossy G,Griffiths P,Kernoff P

更新日期：1991-11-02 00:00:00

abstract：OBJECTIVE:To explore genetic and environmental contributions to the influence of parental social class and region of upbringing on adult human fatness. DESIGN:Survey of sample of adults who had been adopted in childhood to relate their body mass index to sociodemographic variables in a series of multiple linear regres...

journal_title：BMJ (Clinical research ed.)

authors： Teasdale TW,Sørensen TI,Stunkard AJ

更新日期：1990-06-23 00:00:00

abstract：OBJECTIVE:To cost the relation between socioeconomic status and various measures of primary care workload and assess the adequacy of current "deprivation" payments in relation to actual costings for patients living in qualifying areas. DESIGN:Retrospective data on primary care were collected over a 4.5 year period fro...

journal_title：BMJ (Clinical research ed.)

authors： Worrall A,Rea JN,Ben-Shlomo Y

更新日期：1997-01-04 00:00:00

abstract：OBJECTIVE:To investigate the risks of adverse pregnancy and birth outcomes for treated and untreated bipolar disorder during pregnancy. DESIGN:Population based cohort study using data from national health registers. SETTING:Sweden. PARTICIPANTS:332,137 women with a last menstrual period anytime after 1 July 2005 and...

journal_title：BMJ (Clinical research ed.)

authors： Bodén R,Lundgren M,Brandt L,Reutfors J,Andersen M,Kieler H

更新日期：2012-11-08 00:00:00

abstract：OBJECTIVE:To determine whether the link suggested between growth in utero and during infancy and death from cardiovascular disease in men is also present in women. DESIGN:Follow up study of women and men whose birth weight and weight at 1 year of age had been recorded. SETTING:Hertfordshire, England. SUBJECTS:5585 w...

journal_title：BMJ (Clinical research ed.)

authors： Osmond C,Barker DJ,Winter PD,Fall CH,Simmonds SJ

更新日期：1993-12-11 00:00:00

abstract：OBJECTIVE:To examine the associations between neuraxial anaesthesia or general anaesthesia and clinical outcomes, length of hospital stay, and readmission in adults undergoing lower limb revascularisation surgery. DESIGN:Comparative effectiveness study using linked, validated, population based databases. SETTING:Onta...

journal_title：BMJ (Clinical research ed.)

authors： Roberts DJ,Nagpal SK,Kubelik D,Brandys T,Stelfox HT,Lalu MM,Forster AJ,McCartney CJ,McIsaac DI

更新日期：2020-11-25 00:00:00

abstract：OBJECTIVES:To review completed trials assessing effect of hormone replacement therapy on subsequent risk of stroke, assessing stroke by pathological type, severity, and outcome. DESIGN:Systematic review of randomised controlled trials identified from the Cochrane Library, Embase, and Medline; reviews; and reference li...

journal_title：BMJ (Clinical research ed.)

authors： Bath PM,Gray LJ

更新日期：2005-02-12 00:00:00

abstract：OBJECTIVES:To calculate socioeconomic and health status measures for the primary care groups in London and to examine the association between these measures and hospital admission rates. DESIGN:Cross sectional study. SETTING:66 primary care groups in London, total list size 8.0 million people. MAIN OUTCOME MEASURES:...

journal_title：BMJ (Clinical research ed.)

authors： Majeed A,Bardsley M,Morgan D,O'Sullivan C,Bindman AB

更新日期：2000-10-28 00:00:00

abstract：:A random sample of 133 elderly patients who had an unplanned readmission to a district general hospital within 28 days of discharge from hospital was studied and compared with a matched control sample of patients who were not readmitted. The total group was drawn from all specialties in the hospital, and by interviewi...

journal_title：BMJ (Clinical research ed.)

authors： Williams EI,Fitton F

更新日期：1988-09-24 00:00:00

abstract：OBJECTIVES:To quantify the relative contribution of premorbid and episode specific factors in determining the long term persistence of disabling symptoms of low back pain. DESIGN:Prospective cohort study. SETTING:Two general practices in the south Manchester area. PARTICIPANTS:180 patients, who previously participat...

journal_title：BMJ (Clinical research ed.)

authors： Thomas E,Silman AJ,Croft PR,Papageorgiou AC,Jayson MI,Macfarlane GJ

更新日期：1999-06-19 00:00:00

abstract：OBJECTIVE:To test the hypothesis of an association between neonatal intramuscular vitamin K and childhood leukaemia and other cancers. DESIGN:Population based case-control study with data abstracted from hospital records. SETTING:Scotland. SUBJECTS:Children aged 0-14 years resident in Scotland from 1991-4 and diagno...

journal_title：BMJ (Clinical research ed.)

authors： McKinney PA,Juszczak E,Findlay E,Smith K

更新日期：1998-01-17 00:00:00

abstract：OBJECTIVES:To assess the incidence, time of day, and driver morbidity associated with vehicle accidents where the most likely cause was the driver falling asleep at the wheel. DESIGN:Two surveys were undertaken, in southwest England and the midlands, by using police databases or on the spot interviews. SUBJECTS:Drive...

journal_title：BMJ (Clinical research ed.)

authors： Horne JA,Reyner LA

更新日期：1995-03-04 00:00:00

abstract：OBJECTIVE:Detailed analysis of primary cutaneous melanoma first diagnosed in Scotland in patients aged 65 and over. DESIGN:Comparison of changing incidence, sex distribution, site, histogenetic type, tumour thickness, and prognosis of all primary cutaneous melanomas in patients aged 65 and over diagnosed in Scotland i...

journal_title：BMJ (Clinical research ed.)

authors： McHenry PM,Hole DJ,MacKie RM

更新日期：1992-03-21 00:00:00

abstract：OBJECTIVE:To examine the relation between diameters of the retinal arterioles and 10 year incidence of hypertension. DESIGN:Population based prospective cohort study. SETTING:Beaver Dam eye study. PARTICIPANTS:2451 normotensive people aged 43 to 84 years. MAIN OUTCOME MEASURES:Diameters of retinal arterioles and ve...

journal_title：BMJ (Clinical research ed.)

authors： Wong TY,Shankar A,Klein R,Klein BE,Hubbard LD

更新日期：2004-07-10 00:00:00

abstract：:The treatment of renal cell carcinoma (RCC) has changed greatly over the past 15 years. Progress in the surgical management of the primary tumor and increased understanding of the molecular biology and genomics of the disease have led to the development of new therapeutic agents. The management of the primary tumor ha...

journal_title：BMJ (Clinical research ed.)

authors： Jonasch E,Gao J,Rathmell WK

更新日期：2014-11-10 00:00:00

abstract：OBJECTIVE:To compare the effectiveness of manipulative therapy, physiotherapy, treatment by the general practitioner, and placebo therapy in patients with persistent non-specific back and neck complaints. DESIGN:Randomised clinical trial. SETTING:Primary health care in the Netherlands. PATIENTS:256 patients with non...

journal_title：BMJ (Clinical research ed.)

authors： Koes BW,Bouter LM,van Mameren H,Essers AH,Verstegen GM,Hofhuizen DM,Houben JP,Knipschild PG

更新日期：1992-03-07 00:00:00

abstract：:In the wake of the death of an 11-year-old girl the Egyptian government has banned any government-affiliated medical staff from performing female circumcision. Egyptian health policy has shifted from trying to control the practice by keeping it under government supervision towards condemnation. In October 1995 the h...

journal_title：BMJ (Clinical research ed.)

authors： Wiens J

更新日期：1996-08-03 00:00:00

abstract：OBJECTIVE:To assess the risk of bias associated with missing outcome data in systematic reviews. DESIGN:Imputation study. SETTING:Systematic reviews. POPULATION:100 systematic reviews that included a group level meta-analysis with a statistically significant effect on a patient important dichotomous efficacy outcome...

journal_title：BMJ (Clinical research ed.)

authors： Kahale LA,Khamis AM,Diab B,Chang Y,Lopes LC,Agarwal A,Li L,Mustafa RA,Koujanian S,Waziry R,Busse JW,Dakik A,Schünemann HJ,Hooft L,Scholten RJ,Guyatt GH,Akl EA

更新日期：2020-08-26 00:00:00

abstract：:Prediction models are developed to aid health care providers in estimating the probability or risk that a specific disease or condition is present (diagnostic models) or that a specific event will occur in the future (prognostic models), to inform their decision making. However, the overwhelming evidence shows that th...

journal_title：BMJ (Clinical research ed.)

authors： Collins GS,Reitsma JB,Altman DG,Moons KG

更新日期：2015-01-07 00:00:00

abstract：OBJECTIVE:To quantify the association between exposure to higher temperatures and the risk of myocardial infarction at an hourly temporal resolution. DESIGN:Case-crossover study. SETTING:England and Wales Myocardial Ischaemia National Audit Project (MINAP) database. PARTICIPANTS:24,861 hospital admissions for myocar...

journal_title：BMJ (Clinical research ed.)

authors： Bhaskaran K,Armstrong B,Hajat S,Haines A,Wilkinson P,Smeeth L

更新日期：2012-12-13 00:00:00

abstract：OBJECTIVE:To examine whether there are too many hospital beds in London. DESIGN:Analysis of data from the Hospital In-Patient Enquiry, Mental Health Enquiry, health service indicators, and Emergency Bed Service. SETTING:England, London, and inner London. RESULTS:Hospital admission rates for acute plus geriatric serv...

journal_title：BMJ (Clinical research ed.)

authors： Jarman B

更新日期：1993-04-10 00:00:00

abstract：OBJECTIVE:To determine the effect of withdrawing diuretic drugs on oedema in patients prescribed them for only ankle oedema, excluding patients with cardiac, hepatic, or renal failure. DESIGN:Randomised controlled trial. SETTING:15 general practices in the Netherlands. PATIENTS:1202 patients aged 65 years or older a...

journal_title：BMJ (Clinical research ed.)

authors： de Jonge JW,Knottnerus JA,van Zutphen WM,de Bruijne GA,Struijker Boudier HA

更新日期：1994-02-19 00:00:00

abstract：OBJECTIVE:Although the Polypill concept (proposed in 2003) is promising in terms of benefits for cardiovascular risk management, the potential costs and adverse effects are its main pitfalls. The objective of this study was to identify a tastier and safer alternative to the Polypill: the Polymeal. METHODS:Data on the ...

journal_title：BMJ (Clinical research ed.)

authors： Franco OH,Bonneux L,de Laet C,Peeters A,Steyerberg EW,Mackenbach JP

更新日期：2004-12-18 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of a two year exercise programme of progressive balance retraining in reducing injurious falls among women aged 75-85 at increased risk of falls and injuries and living in the community. DESIGN:Pragmatic multicentre, two arm, parallel group, randomised controlled trial. SETTING:2...

journal_title：BMJ (Clinical research ed.)

authors： El-Khoury F,Cassou B,Latouche A,Aegerter P,Charles MA,Dargent-Molina P

更新日期：2015-07-22 00:00:00

abstract：OBJECTIVES:To examine the individual and combined associations of unhealthy behaviours (low/intermediate physical activity, consuming fruit and vegetables less than once a day, current smoking/short term ex-smoking, never/former/heavy alcohol drinking), assessed at start of follow-up, with hazard of disability among ol...

journal_title：BMJ (Clinical research ed.)

authors： Artaud F,Dugravot A,Sabia S,Singh-Manoux A,Tzourio C,Elbaz A

更新日期：2013-07-23 00:00:00