An in vitro procedure for the estimation of thyroid hormone releasing factors in sera of thyrotoxic patients.

abstract：:Evaluation of thyroid status by measurement of free thyroid hormone concentrations seems particularly helpful in conditions with altered serum binding proteins. In pregnancy, a condition of increased thyroxine binding globulin, serum free thyroxine (FT4) and free triiodothyronine (FT3) concentrations have been reporte...

journal_title：Journal of endocrinological investigation

authors： Roti E,Gardini E,Minelli R,Bianconi L,Flisi M

更新日期：1991-01-01 00:00:00

abstract：:We investigated ACTH and cortisol responses after ovine CRF injection (1 microgram/kg one bolus) in a group of 11 drug-free patients suffering from major depression. When compared to sex- and age-matched normal controls, our depressed patients showed: Higher ACTH basal values (p less than 0.002); higher cortisol basal...

journal_title：Journal of endocrinological investigation

authors： Nerozzi D,Bersani G,Melia E,Magnani A,Antonozzi I,Frajese G

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Fine needle cytology aspirates (FNA) classified as THY4 are a heterogeneous group suspicious for malignancy [papillary thyroid cancer (PTC)], which is confirmed in 50-80% of cases after surgery. AIM:To better stratify THY4 FNA specimens for the relative risk of malignancy. METHODS:We retrospectively analyz...

journal_title：Journal of endocrinological investigation

authors： Arena S,Latina A,Marturano I,Muscia V,La Rosa GL,Stornello M,Squatrito S,Italia S,Vigneri R

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:We previously identified a four-generation family with medullary thyroid cancer (MTC) and a germline p.Y791F RET mutation whose cancer lacked a strong genotype-phenotype correlation. The entire gene coding region of the RET gene should be sequenced when genotype-phenotype discrepancies are observed in patien...

journal_title：Journal of endocrinological investigation

authors： Valente FO,Dias da Silva MR,Camacho CP,Kunii IS,Bastos AU,da Fonseca CC,Simião HP,Tamanaha R,Maciel RM,Cerutti JM

更新日期：2013-12-01 00:00:00

abstract：:Juvenile Rheumatoid Arthritis (JRA) is frequently associated with osteoporosis. In order to determine if JRA osteoporosis is related to reduced formation or to increased bone resorption or both, serum levels of calcium (Ca), phosphorus (PO4), magnesium (Mg), alkaline phosphatase (ALP), parathormone (PTHi), 25-hydroxyv...

journal_title：Journal of endocrinological investigation

authors： Falcini F,Ermini M,Bagnoli F

更新日期：1998-01-01 00:00:00

abstract：:The aim of acromegaly treatment is to control the disease by suppressing GH hyperactivity and reducing the size or impeding the growth of the pituitary GH secreting mass. Over recent years, many studies have emphasized the role of SS analogs in the treatment of acromegaly. In fact, SS analogs have been demonstrated to...

journal_title：Journal of endocrinological investigation

authors： Gola M,Bonadonna S,Mazziotti G,Amato G,Giustina A

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the hypothesis that interleukin-1beta (IL-1beta) might be involved in the increase of the circulating levels of placental-derived CRH leading to the initiation of pre-term labor. SUBJECTS AND METHODS:Forty-eight primigravidae with a singleton viable pregnancy between ...

journal_title：Journal of endocrinological investigation

authors： Vitoratos N,Mastorakos G,Kountouris A,Papadias K,Creatsas G

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:We did a meta-analysis with meta-regression to evaluate the relationship between hemoglobin A1c (A1C) reduction and the primary CV outcome of cardiovascular outcome trials (CVOTs). METHODS:We used a random effects meta-analysis of the 12 CVOTs to quantify the effect of A1C reduction on major cardiovascular eve...

journal_title：Journal of endocrinological investigation

authors： Giugliano D,Chiodini P,Maiorino MI,Bellastella G,Esposito K

更新日期：2019-10-01 00:00:00

abstract：:Seasonal plasma testosterone and androstenedione levels were determined by radioimmunoassay in the Gentile di Puglia ram. Androstenedione remains steady throughout the years, while testosterone shows seasonal changes. Testosterone is at high levels in winter, spring and summer and drops to a low concentration in autum...

journal_title：Journal of endocrinological investigation

authors： Dell'Aquila S,Crasto A,Alberico G,Varriale B,Pelosi A,Pierantoni R

更新日期：1985-06-01 00:00:00

abstract：:The occurrence of metabolic bone disease in patients with renal dysfunction is due to the key role played by the kidney in regulating calcium-phosphate metabolism. The incidence of hip fractures in end-stage renal disease is 3- to 4-fold higher than the general population, while poor data about vertebral fractures sho...

journal_title：Journal of endocrinological investigation

authors： Fusaro M,D'Angelo A,Scalzo G,Gallieni M,Giannini S,Guglielmi G

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Serum DHEAS has been found to be elevated in some women with polycystic ovary syndrome (PCOS). We wished to determine whether this prevalence is different in women with androgen excess who have different phenotypes and to correlate these findings with various cardiovascular and metabolic parameters. METHODS...

journal_title：Journal of endocrinological investigation

authors： Carmina E,Lobo RA

更新日期：2007-02-01 00:00:00

abstract：:The authors report the results of a correlation study between the direct Immunobead Test (d-IBT) and other techniques for antisperm antibodies detection. The Gelatin Agglutination Test (GAT) and Tray Agglutination Test (TAT) were used to detect antibodies in blood serum and seminal plasma ("indirect methods"). The Dir...

journal_title：Journal of endocrinological investigation

authors： Dondero F,Lenzi A,Gandini L,Lombardo F,Culasso F

更新日期：1991-06-01 00:00:00

abstract：:Thyroid-stimulating antibody (TSAb) activity and the TSH-binding inhibitory immunoglobulin (TBII) index were assessed in 158 patients with Graves' disease who had been treated with 131I 6-14 years earlier. Twenty-one patients (13%) were still hyperthyroid, 45 (28%) were euthyroid, 44 (28%) were subclinically hypothyro...

journal_title：Journal of endocrinological investigation

authors： Yoshida K,Aizawa Y,Kaise N,Fukazawa H,Kiso Y,Sayama N,Mori K,Hori H,Abe K

更新日期：1996-11-01 00:00:00

abstract：:Plasma levels and 24-h urinary excretion of cyclic AMP and cyclic GMP were measured in 18 patients with hyperthyroidism, 7 patients with hypothyroidism and 25 normal subjects. Mean plasma and urinary levels of both cyclic AMP and cyclic GMP were significantly positive correlations between the serum thyroid hormone lev...

journal_title：Journal of endocrinological investigation

authors： Peracchi M,Bamonti-Catena F,Lombardi L,Reschini E,Toschi V,Maiolo AT,Polli EE

更新日期：1983-06-01 00:00:00

abstract：:Forty-three euthyroid patients with a single, solid, nonfunctioning thyroid nodule were submitted to fine needle aspiration biopsy and serum thyroglobulin (Tg) was measured before and after (48h) 10 U of bovine TSH. Twenty-two normal subjects were also submitted to the bTSH test. Patients with nonfunctioning nodules w...

journal_title：Journal of endocrinological investigation

authors： Leite Z,Carneiro P,Halpern A,Medeiros-Neto G

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:Successful parathyroidectomy (PTX) often results in a dramatic drop in the parathyroid hormone (PTH) levels, relieves the patient from clinical symptoms, and reduces mortality. Although PTX is generally a successful treatment for progressive secondary hyperparathyroidism (SHPT) patients subjected to surgery,...

journal_title：Journal of endocrinological investigation

authors： Xu D,Yin Y,Hou L,Dai W

更新日期：2016-05-01 00:00:00

abstract：:Although the role of biogenic amines in the regulation of gonadotropin release has been studied extensively, the precise role of dopamine (DA) in stimulating LHRH and/or LH release is still controversial. In the present study 6 eugonadal women, aged 20-30, were given an LHRH infusion on day 6 of the menstrual cycle an...

journal_title：Journal of endocrinological investigation

authors： Pucci E,Franchi F,Kicovic PM,Sgrilli R,Barletta D,Argenio GF,Gasperi M,Bernini GP,Luisi M

更新日期：1981-01-01 00:00:00

abstract：:The present study reports the biochemical and immunohistochemical findings in the cytosol of a Hürthle cell carcinoma as compared with that of normal thyroid tissue. Sephadex G-200 chromatography of the extract derived from a Hürthle cell carcinoma and from normal thyroid tissue revealed three identical pools. Pool I ...

journal_title：Journal of endocrinological investigation

authors： De Keyser L,Layfield L,Van Herle A,Costin A,Lewin K

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:Type 1 diabetes (T1DM) is an autoimmune disease in which both genetic and environmental factors play a role in the etiology. AIM:The aim of this study was to analyze the incidence of T1DM. METHODS:A retrospective technique was used to register all newly diagnosed cases of T1DM in Belgrade (Serbia) children...

journal_title：Journal of endocrinological investigation

authors： Sipetic S,Maksimovic J,Vlajinac H,Ratkov I,Sajic S,Zdravkovic D,Sipetic T

更新日期：2013-05-01 00:00:00

abstract：:Hexarelin (Hex) is a synthetic hexapeptide with potent GH-releasing activity in both animals and men. Aim of this study was to evaluate the GH response to a maximal dose of Hex and GH-releasing hormone (GHRH) in a group of patients with Prader-Willi syndrome (PWS). Seven patients (4 boys and 3 girls, age 2.4-14.2 yr) ...

journal_title：Journal of endocrinological investigation

authors： Cappa M,Raguso G,Palmiotto T,Faedda A,Gurreri F,Neri G,Deghenghi R,Loche S

更新日期：1998-09-01 00:00:00

abstract：:Osteocalcin (OC) concentration, a specific index of bone formation, was measured in 29 female patients with microprolactinoma (serum prolactin, PRL: 105 +/- 10.9 ng/ml; mean +/- SE). Mean OC levels were significantly lower than in controls (1.7 +/- 0.2 vs 5.1 +/- 0.3 ng/ml; p less than 0.001), being below the normal r...

journal_title：Journal of endocrinological investigation

authors： Sartorio A,Conti A,Ambrosi B,Muratori M,Morabito F,Faglia G

更新日期：1990-05-01 00:00:00

abstract：:The effects of growth hormone-releasing hormone (GHRH) were studied on densely granulated somatotroph adenoma cells and sparsely granulated somatotroph adenoma cells in culture by measuring release of growth hormone (GH) as well as ultrastructural morphometrical parameters and comparing them with those of control aden...

journal_title：Journal of endocrinological investigation

authors： Kawakita S,Asa SL,Kovacs K

更新日期：1989-07-01 00:00:00

abstract：:Leptin, insulin, ghrelin, and IGF-I are circulating peptide hormones concerned with energy homeostasis and the regulation of GH axis. They are present in human milk, and are thought to promote neonatal development. The aim of the present study was to detect these substances in goat milk and determine whether their lev...

journal_title：Journal of endocrinological investigation

authors： Rosi F,Aufy AA,Magistrelli D

更新日期：2009-06-01 00:00:00

abstract：:Traumatic brain injury (TBI) combined with fractures of long bones or large joints is often associated with enhanced osteogenesis (early fracture healing accompanied by hypertrophic callus formation and/or heterotopic ossifications). Humoral factors that cause enhanced osteogenesis in patients with TBI are not yet ide...

journal_title：Journal of endocrinological investigation

authors： Wildburger R,Zarkovic N,Tonkovic G,Skoric T,Frech S,Hartleb M,Loncaric I,Zarkovic K

更新日期：1998-02-01 00:00:00

abstract：PURPOSE:Aims of this study were to evaluate the agreement between the short and long versions of the International Physical Activity Questionnaire (IPAQ: Italian versions), their reproducibility (agreement and reliability) and construct validity (relative to pedometry) in a clinical population. METHODS:Ninety patients...

journal_title：Journal of endocrinological investigation

authors： Minetto MA,Motta G,Gorji NE,Lucini D,Biolo G,Pigozzi F,Portincasa P,Maffiuletti NA

更新日期：2018-03-01 00:00:00

abstract：PURPOSE:Visceral adipose tissue-derived serine protease inhibitor (vaspin) is an adipocytokine with insulin-sensitizing effects. Accumulating data implied that vaspin represents a compensatory mechanism but it is unknown how vaspin change during ageing. This study was designed to examine the correlation between plasma ...

journal_title：Journal of endocrinological investigation

authors： Xu X,Wen J,Lu Y,Ji H,Zhuang J,Su Y,Liu B,Li H,Xu Y

更新日期：2017-02-01 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH)-like material was found in human retina obtained at autopsy from eyes used for corneal grafts. The TRH-like material was extracted with methanol and was found to be indistinguishable from synthetic TRH in its immunoreactivity and bioreactivity and in its proteolytic degradation by f...

journal_title：Journal of endocrinological investigation

authors： Martino E,Nardi M,Vaudagna G,Simonetti S,Cilotti A,Pinchera A,Venturi G,Seo H,Baschieri L

更新日期：1980-07-01 00:00:00

abstract：AIMS AND METHODS:Factor analysis is a multivariate correlation technique frequently employed to characterise the aggregation of abnormalities underlying the metabolic syndrome (MS), but scarcely used in obese adolescents. Aim of the study was to investigate the clustering of anthropometric and metabolic variables relat...

journal_title：Journal of endocrinological investigation

authors： Lafortuna CL,Adorni F,Agosti F,De Col A,Zennaro R,Caranti D,Sartorio A

更新日期：2009-06-01 00:00:00

abstract：:Thyroid diseases may lead to endothelial dysfunction; however, the mechanism underlying the endothelial dysfunction in thyroid disease is not clear yet. Asymmetric dimethylarginine (ADMA), a novel inhibitor of endothelial nitric oxide synthase (eNOS), blocks nitric oxide (NO) synthesis from L-arginine. Symmetric dimet...

journal_title：Journal of endocrinological investigation

authors： Arikan E,Karadag CH,Guldiken S

更新日期：2007-03-01 00:00:00

abstract：:There is increasing evidence that androgen therapy in men may be effectively applied in several conditions to improve well being and health. Classical indications for androgen therapy in males are represented by primary or secondary hypogonadism, delayed puberty, aplastic anemia and that secondary to chronic renal fai...

journal_title：Journal of endocrinological investigation

authors： Gambineri A,Pasquali R

更新日期：2000-03-01 00:00:00