Association of cardiovascular disease risk factors with socioeconomic position during childhood and during adulthood.

abstract：OBJECTIVE:To investigate whether an important football match increases stress to such an extent that it triggers acute myocardial infarction and stroke. DESIGN:Longitudinal study of mortality around 22 June 1996 (the day the Dutch football team was eliminated from the European football championship). Mortality on 22 J...

journal_title：BMJ (Clinical research ed.)

authors： Witte DR,Bots ML,Hoes AW,Grobbee DE

更新日期：2000-12-23 00:00:00

abstract：OBJECTIVE:To examine the effectiveness of day hospital attendance in prolonging independent living for elderly people. DESIGN:Systematic review of 12 controlled clinical trials (available by January 1997) comparing day hospital care with comprehensive care (five trials), domiciliary care (four trials), or no comprehen...

journal_title：BMJ (Clinical research ed.)

authors： Forster A,Young J,Langhorne P

更新日期：1999-03-27 00:00:00

abstract：OBJECTIVE:To determine the efficacy and safety of the anticoagulant fondaparinux in older acute medical inpatients at moderate to high risk of venous thromboembolism. DESIGN:Double blind randomised placebo controlled trial. SETTING:35 centres in eight countries. PARTICIPANTS:849 medical patients aged 60 or more admi...

journal_title：BMJ (Clinical research ed.)

authors： Cohen AT,Davidson BL,Gallus AS,Lassen MR,Prins MH,Tomkowski W,Turpie AG,Egberts JF,Lensing AW,ARTEMIS Investigators.

更新日期：2006-02-11 00:00:00

abstract：OBJECTIVE:To describe the progression of HIV disease in a haemophilic cohort and to show the influence of treatment. DESIGN:11 year longitudinal clinical and laboratory study. SETTING:A haemophilia centre. PATIENTS:111 patients infected with HIV during October 1979 to July 1985. MAIN OUTCOME MEASURES:Symptoms of HI...

journal_title：BMJ (Clinical research ed.)

authors： Lee CA,Phillips AN,Elford J,Janossy G,Griffiths P,Kernoff P

更新日期：1991-11-02 00:00:00

abstract：:Stroke is the leading cause of long term disability in developed countries and one of the top causes of mortality worldwide. The past decade has seen substantial advances in the diagnostic and treatment options available to minimize the impact of acute ischemic stroke. The key first step in stroke care is early identi...

journal_title：BMJ (Clinical research ed.)

authors： Phipps MS,Cronin CA

更新日期：2020-02-13 00:00:00

abstract：:Physical examination of the cardiovascular system is central to contemporary teaching and practice in clinical medicine. Evidence about its value focuses on its diagnostic accuracy and varies widely in methodological quality and statistical power. This makes collation, analysis, and understanding of results difficult ...

journal_title：BMJ (Clinical research ed.)

authors： Elder A,Japp A,Verghese A

更新日期：2016-07-27 00:00:00

abstract：OBJECTIVE:To identify and estimate the population costs and effects of a selected set of enforcement strategies for reducing the burden of road traffic injuries in developing countries. DESIGN:Cost effectiveness analysis based on an epidemiological model. SETTING:Two epidemiologically defined World Health Organizatio...

journal_title：BMJ (Clinical research ed.)

authors： Chisholm D,Naci H,Hyder AA,Tran NT,Peden M

更新日期：2012-03-02 00:00:00

abstract：OBJECTIVES:To examine the association between environmental exposure to takeaway food outlets, takeaway food consumption, and body weight, while accounting for home, work place, and commuting route environments. DESIGN:Population based, cross sectional study, using data on individual participants' diet and weight, and...

journal_title：BMJ (Clinical research ed.)

authors： Burgoine T,Forouhi NG,Griffin SJ,Wareham NJ,Monsivais P

更新日期：2014-03-13 00:00:00

abstract：OBJECTIVES:To gain insight into people's thoughts on stroke and to inform the development of educational strategies in the community. DESIGN:Focus group discussions: two groups of people who had a stroke and their carers, and two groups of members of the general public. SETTING:New South Wales, Australia. PARTICIPAN...

journal_title：BMJ (Clinical research ed.)

authors： Yoon SS,Byles J

更新日期：2002-05-04 00:00:00

abstract：OBJECTIVES:To determine the strength of evidence for the effectiveness of mental health interventions for patients with three common somatic conditions (chronic fatigue syndrome, irritable bowel syndrome, and chronic back pain). To assess whether results obtained in secondary care can be extrapolated to primary care an...

journal_title：BMJ (Clinical research ed.)

authors： Raine R,Haines A,Sensky T,Hutchings A,Larkin K,Black N

更新日期：2002-11-09 00:00:00

abstract：:A study was conducted to investigate a novel approach to the prophylaxis of schizophrenic relapse. The treatment strategy comprised brief intermittent courses of neuroleptic agents begun as soon as non-psychotic symptoms believed to be early signs of relapse appeared. Fifty four stable, remitted outpatients meeting th...

journal_title：BMJ (Clinical research ed.)

authors： Jolley AG,Hirsch SR,McRink A,Manchanda R

更新日期：1989-04-15 00:00:00

abstract：OBJECTIVE:To determine whether abnormal results for liver function tests are investigated in primary care and findings on full investigation. DESIGN:Retrospective audit and prospective clinical investigation. SETTING:University hospital and surrounding general practices serving around 330 000 people. SUBJECTS:Adults...

journal_title：BMJ (Clinical research ed.)

authors： Sherwood P,Lyburn I,Brown S,Ryder S

更新日期：2001-02-03 00:00:00

abstract：OBJECTIVES:To compare the efficacy and tolerability of butterbur (Petasites hybridus) with cetirizine in patients with seasonal allergic rhinitis (hay fever). DESIGN:Randomised, double blind, parallel group comparison. SETTING:Four outpatient general medicine and allergy clinics in Switzerland and Germany. PARTICIPA...

journal_title：BMJ (Clinical research ed.)

authors： Schapowal A,Petasites Study Group.

更新日期：2002-01-19 00:00:00

abstract：OBJECTIVE:To examine differences in morbidity and mortality due to non-insulin dependent diabetes in African Caribbeans and Europeans. DESIGN:Cohort study of patients with non-insulin dependent diabetes drawn from diabetes clinics in London. Baseline investigations were performed in 1975-7; follow up continued until 1...

journal_title：BMJ (Clinical research ed.)

authors： Chaturvedi N,Jarrett J,Morrish N,Keen H,Fuller JH

更新日期：1996-10-05 00:00:00

abstract：OBJECTIVE:To assess the cost-effectiveness of low dose statins for primary prevention of vascular disease, incorporating current prices, non-adherence (reduced clinical efficacy while maintaining healthcare costs), and the results of the recently published JUPITER trial. DESIGN:Cost-effectiveness analysis using a Mark...

journal_title：BMJ (Clinical research ed.)

authors： Greving JP,Visseren FL,de Wit GA,Algra A

更新日期：2011-03-30 00:00:00

abstract：OBJECTIVE:To determine whether screening Danish men aged 65 or more for abdominal aortic aneurysms reduces mortality. DESIGN:Single centre randomised controlled trial. SETTING:All five hospitals in Viborg County, Denmark. PARTICIPANTS:All 12,639 men born during 1921-33 and living in Viborg County. In 1994 we include...

journal_title：BMJ (Clinical research ed.)

authors： Lindholt JS,Juul S,Fasting H,Henneberg EW

更新日期：2005-04-02 00:00:00

abstract：OBJECTIVE:To evaluate the association between migraine and cognitive decline among women. DESIGN:Prospective cohort study. SETTING:Women's Health Study, United States. PARTICIPANTS:6349 women aged 65 or older enrolled in the Women's Health Study who provided information about migraine status at baseline and particip...

journal_title：BMJ (Clinical research ed.)

authors： Rist PM,Kang JH,Buring JE,Glymour MM,Grodstein F,Kurth T

更新日期：2012-08-08 00:00:00

abstract：OBJECTIVES:To provide a contemporary account of the treatment and outcomes of acute coronary attacks in England and Wales and to identify strategies that might improve the outcome. DESIGN:Two year community and hospital based study in three British health districts. SETTING:Health districts of Brighton (population 28...

journal_title：BMJ (Clinical research ed.)

authors： Norris RM

更新日期：1998-04-04 00:00:00

abstract：OBJECTIVE:To assess the association between genitourinary infections in the month before conception to the end of the first trimesterand gastroschisis. DESIGN:Case-control study with self reported infections from a computer assisted telephone interview. SETTING:National birth defects prevention study, a multisite, po...

journal_title：BMJ (Clinical research ed.)

authors： Feldkamp ML,Reefhuis J,Kucik J,Krikov S,Wilson A,Moore CA,Carey JC,Botto LD

更新日期：2008-06-21 00:00:00

abstract：OBJECTIVE:To characterise the complete case series of influenza A/H7N9 infections as of 27 May 2013, detected by China's national sentinel surveillance system for influenza-like illness. DESIGN:Case series. SETTING:Outpatient clinics and emergency departments of 554 sentinel hospitals across 31 provinces in mainland ...

journal_title：BMJ (Clinical research ed.)

authors： Ip DK,Liao Q,Wu P,Gao Z,Cao B,Feng L,Xu X,Jiang H,Li M,Bao J,Zheng J,Zhang Q,Chang Z,Li Y,Yu J,Liu F,Ni MY,Wu JT,Cowling BJ,Yang W,Leung GM,Yu H

更新日期：2013-06-24 00:00:00

abstract：OBJECTIVE:To determine whether elderly people can learn to use the inhaler used to deliver zanamivir (Relenza Diskhaler) as effectively as the Turbohaler and to identify which aspects of inhaler technique are most problematic. DESIGN:Randomised, controlled, intervention study. SETTING:Wards for acute elderly care in ...

journal_title：BMJ (Clinical research ed.)

authors： Diggory P,Fernandez C,Humphrey A,Jones V,Murphy M

更新日期：2001-03-10 00:00:00

abstract：:Molecular techniques have revolutionised our knowledge of cell and tissue function in both health and disease. We already have new and powerful treatments based on an understanding of communication between cells by messenger molecules called cytokines. Furthermore, there is great therapeutic promise in defining molecu...

journal_title：BMJ (Clinical research ed.)

authors： Savill J

更新日期：1997-01-18 00:00:00

abstract：OBJECTIVE: To measure the association between a surgeon's degree of specialization in a specific procedure and patient mortality. DESIGN: Retrospective analysis of Medicare data. SETTING: US patients aged 66 or older enrolled in traditional fee for service Medicare. PARTICIPANTS: 25 152 US surgeons who performed one...

journal_title：BMJ (Clinical research ed.)

authors： Sahni NR,Dalton M,Cutler DM,Birkmeyer JD,Chandra A

更新日期：2016-07-21 00:00:00

abstract：OBJECTIVE:To review the evidence base from randomised controlled trials of combined cardiac resynchronisation therapy and implantable cardioverter defibrillator therapy in left ventricular impairment and symptomatic heart failure. DESIGN:Bayesian network meta-analysis. DATA SOURCES:Medline, Embase, and Cochrane datab...

journal_title：BMJ (Clinical research ed.)

authors： Lam SK,Owen A

更新日期：2007-11-03 00:00:00

abstract：:The development of a molecular genetics diagnostic service over a three year period was studied in a National Health Service region with a population of three million. Starting from a time when few diagnostic applications were possible, the number of disorders and the overall demand had grown rapidly. Conditions for w...

journal_title：BMJ (Clinical research ed.)

authors： Meredith AL,Upadhyaya M,Harper PS

更新日期：1988-10-01 00:00:00

abstract：OBJECTIVES:To investigate whether routinely collected data from hospital episode statistics could be used to identify the gynaecologist Rodney Ledward, who was suspended in 1966 and was the subject of the Ritchie inquiry into quality and practice within the NHS. DESIGN:A mixed scanning approach was used to identify se...

journal_title：BMJ (Clinical research ed.)

authors： Harley M,Mohammed MA,Hussain S,Yates J,Almasri A

更新日期：2005-04-23 00:00:00

abstract：:Research in general practice is becoming increasingly popular, and most general practitioners will sooner or later have to decide whether to become involved with clinical trials sponsored by drug companies. This paper outlines the advantages and disadvantages of multicentre research--based on experience of running a r...

journal_title：BMJ (Clinical research ed.)

authors： Waldron HA,Cookson RF

更新日期：1993-11-20 00:00:00

abstract：OBJECTIVES:To investigate whether sending patients a copy of their referral letter can reduce non-attendance at outpatient departments. DESIGN:Blinded randomised controlled trial. SETTING:13 general practices in Exeter, Devon. SUBJECTS:2078 new consultant referrals from 26 doctors. MAIN OUTCOME MEASURES:Non-attenda...

journal_title：BMJ (Clinical research ed.)

authors： Hamilton W,Round A,Sharp D

更新日期：1999-05-22 00:00:00

abstract：OBJECTIVE:To determine the effect of four monthly vitamin D supplementation on the rate of fractures in men and women aged 65 years and over living in the community. DESIGN:Randomised double blind controlled trial of 100 000 IU oral vitamin D3 (cholecalciferol) supplementation or matching placebo every four months ove...

journal_title：BMJ (Clinical research ed.)

authors： Trivedi DP,Doll R,Khaw KT

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To assess the association between macrolide antibiotics prescribing during pregnancy and major malformations, cerebral palsy, epilepsy, attention deficit hyperactivity disorder, and autism spectrum disorder in children. DESIGN:Population based cohort study. SETTING:The UK Clinical Practice Research Datalink...

journal_title：BMJ (Clinical research ed.)

authors： Fan H,Gilbert R,O'Callaghan F,Li L

更新日期：2020-02-19 00:00:00