Abstract:
:The biological effects of static magnetic fields, and their combined effects with ionizing radiation, were studied using a cultured mammalian cell line (FM3A). The three different modes of magnetic fields evaluated in this report were the 0.3 Tesla (T) field with a gradient of 0.3T/m, the 0.7T field with a gradient of 0.7T/m and the 6.34T field with no gradient. Exposure to the 0.3T and 0.7T fields had no effect on cell survival. Exposure to the 6.34T field decreased cell survival. Survival curves showing the combined effect of the 0.3T and 0.7T fields with radiation had a smaller mean lethal dose (D37) value. The survival curve of the 6.34T field was influenced by the interval between magnetic exposure and ionizing irradiation. When the interval was 6 or 12 h, the survival curve showing the combined effect of the 6.34T field had smaller D37 and quasithreshold dose (Dq) values, indicating the potentiation of the radiation effect. Flow cytometric analysis indicated that exposure to the 0.3T and 0.7T fields showed no change and that exposure to the 6.34T field showed an increase in the percentage of G1 phase cells. Our conclusions were as follows: 1) magnetic fields decreased the colony-forming abilities of cultured mammalian cells; 2) magnetic fields can affect the cell cycle; 3) a stronger magnetic field strength does not always have stronger biological effects and 4) the gradient of a magnetic field may be an important factor when combined with ionizing radiation. Despite the foregoing analysis, the biological effects of magnetic fields on mammalian cells remains a complex phenomena.
journal_name
Nagoya J Med Scijournal_title
Nagoya journal of medical scienceauthors
Zhang XR,Kobayashi H,Hayakawa A,Ishigaki Tsubject
Has Abstractpub_date
1995-12-01 00:00:00pages
157-64issue
3-4eissn
0027-7622issn
2186-3326journal_volume
58pub_type
杂志文章abstract::The distribution of nerve fibers containing either calcitonin gene-related peptide (CGRP) and substance P (SP) was investigated in rat skin with special reference to their relationship to the lymphatic vessels. These nerve fibers exhibited a similar distribution pattern but the former were more numerous than the latte...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::Yokukansankachimpihange (YKSCH), a traditional Japanese medicine, is widely used for the amelioration of the behavioral and psychological symptoms of dementia with digestive dysfunction. Regardless of its successful use for digestive dysfunction, the effect of YKSCH on body weight was unknown. Furthermore, if YKSCH in...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.79.3.351
更新日期:2017-08-01 00:00:00
abstract::The catalytic subunit of human DNA polymerase (pol) delta, p125, was expressed in recombinant baculovirus-infected insect cells, separated from a baculovirus-encoded DNA polymerase, and was purified to homogeneity by affinity trapping with a histidine-octapeptide at the C-terminus of p125 as the ligand. Purified p125 ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract::Aging is accelerated by metabolic and cardiovascular diseases, and the risk of these diseases increases with age. Obesity is an important risk factor for many age-related diseases and is linked to reduced telomere length in white blood cells. We investigated whether cardiac senescence might be enhanced in DahlS.Z-Lepr...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2014-02-01 00:00:00
abstract::A 67-year-old man underwent posterior cervical decompression surgery for ossification of the posterior longitudinal ligament (OPLL) with fixation using cervical pedicle screws (CPSs) guided by intraoperative 3D image-based navigation. Intraoperatively, while creating the screw hole using the navigation probe, the virt...
journal_title:Nagoya journal of medical science
pub_type:
doi:10.18999/nagjms.82.4.799
更新日期:2020-11-01 00:00:00
abstract::Respiratory exposure to asbestos fibers has been associated with diffuse malignant mesothelioma (DMM) in humans. Despite advancements in the molecular analyses of human DMM and the development of animal models, the carcinogenic mechanisms of the disease remain unclear. There are basically three hypotheses regarding th...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章,评审
doi:
更新日期:2009-02-01 00:00:00
abstract::Metabolic syndrome (MetS) is characterized by the presence of atherogenic risk factors, and is associated with a marked increase in the risk of cardiovascular disease. Recently, the criteria of MetS were newly defined in Japan. We examined the relationship between MetS and the various metabolic parameters in Japanese ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract::Stereotactic radiosurgery for large brain metastases (BM) not amenable to surgical resection is associated with limited local control and neurotoxicity, while hypofractionated stereotactic radiotherapy (HFSRT) has emerged as a promising option. We retrospectively evaluated 61 patients with BM larger than 2 cm in the m...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.81.3.397
更新日期:2019-08-01 00:00:00
abstract::Anastomotic leakage after esophagectomy is associated with prolonged hospitalization and increased medical cost. Additionally, it sometimes leads to a fatal condition and impaired postoperative quality of life. During the process of wound healing, β-hydroxy-β-methylbutyrate (HMB) is important for collagen biosynthesis...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.82.1.33
更新日期:2020-02-01 00:00:00
abstract::To evaluate the adaptability of children with cleft lip and/or palate to school, their mental images of the school environment were investigated in a semantic differential method survey using 23 pairs of adjectives. The following eight places on and off the school grounds were chosen as environmental factors; classroo...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract::The increasing burden of noncommunicable diseases (NCDs) in Bangladesh can be attributable to rapid urbanization and coinciding changes in lifestyle accompanied by nutrition transition. The objective of this study is to explore respondents' lived experiences and perceptions relating to NCDs and nutrition change in an ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.80.4.559
更新日期:2018-11-01 00:00:00
abstract::Temporary threshold shifts (TSSs) in vibrotactile perception produced by continuous vibration and repetitive shocks having one complete cycle of a 100 Hz sine wave and exponential decays. The repetition rate of the cycles was 5, 25, 50, or 100/s, while the root-mean-square (r.m.s.) acceleration measured over exposure ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::We investigated the differences in Japanese and United States medical and legal professional opinions on ethical support for clinical ethical issues using the refusal of blood transfusions on the grounds of religious principles as an example of a clinical ethical issue. In ethical support systems for medical instituti...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.82.2.193
更新日期:2020-05-01 00:00:00
abstract::Hyperperfusion syndrome occurs after treatment of a large or giant cerebral aneurysm. Recently, flow-diverter stent placement has emerged as an effective treatment method for a large cerebral aneurysm, but postoperative ipsilateral delayed intraparenchymal hemorrhage occurs in a minority of cases. The mechanism underl...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.81.4.629
更新日期:2019-11-01 00:00:00
abstract::Malignant lymphoma is a heterogeneous category embracing three major types of lymphoid neoplasms: B cell neoplasms, T and NK cell neoplasms, and Hodgkin lymphoma. Within each type, distinct disease entities are defined based on a combination of morphology, immunophenotype, genetic features and clinical syndromes, the ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章,评审
doi:
更新日期:2006-01-01 00:00:00
abstract::Wrapping and graft replacement are two optional procedures for the treatment of dilated ascending aorta at the time of aortic valve replacement (AVR). Wrapping is considered less invasive. The aim of this study was to compare the short- and long-term clinical outcomes as well as the long-term quality of life in patien...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.79.4.443
更新日期:2017-11-01 00:00:00
abstract::A total of 483 hips treated by primary total hip arthroplasty (THA) were investigated to evaluate the surgical skill of the performing surgeon. Surgical trainees operated on 259 hips and instructors on 224 hips. The average age of the patients at the time of THA in the trainee and instructor group was 61.9 and 60.8 ye...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2015-02-01 00:00:00
abstract::Surgical intervention for the treatment of acetabular fracture non-union is often challenging. Here, we present a case of acetabular fracture non-union with pelvic discontinuity in a patient who underwent cemented total hip arthroplasty (THA) after intra- and extra-articular plate fixation. The case was a 70-year-old ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.81.1.113
更新日期:2019-02-01 00:00:00
abstract::The Japan Agency of Medical Research and Development (AMED) has approved the budget for the 5-year project called Establishment of the JAPAN Brain Bank Network, which commenced in 2016. This project was established with the aim of storing brain tissue samples to enable research on the etiologies and mechanisms of psyc...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章,评审
doi:10.18999/nagjms.80.3.309
更新日期:2018-08-01 00:00:00
abstract::To evaluate the circulatory disturbances, sensory disturbances and damage to muscles and joints by chain saw vibration exposure, the process of the deterioration of the symptoms with chain saw operating time was studied. Subjects were classified into eight groups according to TOT (Total Operating Time): Group 0, 46 co...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::Binding of epidermal growth factor (EGF) to its receptor was evaluated in the four cultured choriocarcinoma cell lines BeWo, NaUCC-1, NaUCC-2, and NaUCC-3. Also, the effect of the anti-tumor drugs actinomycin-D (Act-D) and methotrexate (MTX) on the EGF receptor binding was investigated in these cell lines. Incubation ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
abstract::Disorientation responses of animals exposed to microgravity produced by parabolic aircraft flights and also in-space experiments were reviewed. Disoriented postures in floating are largely species-dependent. Reflexive lowered tone of gravity-bearing extensor muscles by labyrinthectomy is not seen in mammals (hamster a...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:1995-12-01 00:00:00
abstract::Prostate specific antigen (PSA) testing plays a major role in prostate cancer screening; however, the low positive predictive value of PSA testing leads to many unnecessary biopsies. Genetic background is one of factors that could cause it. That's why an association between genetic background and PSA levels should be ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章,多中心研究
doi:
更新日期:2013-02-01 00:00:00
abstract::Argon-plasma coagulation, high-frequency electrosurgical snare, laser therapy, and microwave treatment are therapeutic options to reduce tumor-related stenosis of the central airway. These treatments may cause airway fire under a high concentration of oxygen, so FiO2 levels must be ≤40%. This restriction may be danger...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.80.3.411
更新日期:2018-08-01 00:00:00
abstract::The survey involves examining the applications from 142 institutions that have consented to make available all certification applications from 2015 and 2016 to a research project for building a certification system for an ethics committee run by the Agency for Medical Research and Development. The number of certified ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.81.3.501
更新日期:2019-08-01 00:00:00
abstract::We conducted a study of the effect of intravitreal plasmin on retinal thickness in rabbits. Forty rabbit eyes were injected with 0.4, 1, 2, and 5 IU of plasmin (8 eyes/group). The same volume of BSS-plus(®) was injected in control eyes. Four eyes in each group underwent vitrectomy 60 minutes after the injections. The ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2015-02-01 00:00:00
abstract::Communication errors are the most important cause of adverse events in healthcare. The current study aimed to improve hospital-wide employee teamwork and reduce adverse medical events for patients arising from miscommunication. In our hospital, when patient safety incidents and accidents occur, staff from various occu...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.82.4.697
更新日期:2020-11-01 00:00:00
abstract::The Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study) is a long-term cohort study to investigate the interactions among genotypes, lifestyles, and lifestyle-related diseases, especially cancer. This article reports the outline of the baseline survey of the Daiko Study, one site of the J-MICC Study. T...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2011-08-01 00:00:00
abstract::The Japanese Orthopaedic Association has proposed the term "locomotive syndrome" to designate a condition that places a person at high risk for long-term care. However, in daily clinical practice, even when a diagnosis of locomotive syndrome is made, exercise therapy often cannot be successfully performed in some pati...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:10.18999/nagjms.79.1.43
更新日期:2017-02-01 00:00:00
abstract::Little is known about the carbohydrate structure of the platelet von Willebrand factor (vWf). We have analyzed N-linked oligosaccharides from both plasma and platelet vWf by Fluorophore-Assisted-Carbohydrate Electrophoresis (FACE) and isoelectric focusing before and after digestion of the proteins with neuraminidase. ...
journal_title:Nagoya journal of medical science
pub_type: 杂志文章
doi:
更新日期:2000-05-01 00:00:00