Abstract：
:The biological effects of static magnetic fields, and their combined effects with ionizing radiation, were studied using a cultured mammalian cell line (FM3A). The three different modes of magnetic fields evaluated in this report were the 0.3 Tesla (T) field with a gradient of 0.3T/m, the 0.7T field with a gradient of 0.7T/m and the 6.34T field with no gradient. Exposure to the 0.3T and 0.7T fields had no effect on cell survival. Exposure to the 6.34T field decreased cell survival. Survival curves showing the combined effect of the 0.3T and 0.7T fields with radiation had a smaller mean lethal dose (D37) value. The survival curve of the 6.34T field was influenced by the interval between magnetic exposure and ionizing irradiation. When the interval was 6 or 12 h, the survival curve showing the combined effect of the 6.34T field had smaller D37 and quasithreshold dose (Dq) values, indicating the potentiation of the radiation effect. Flow cytometric analysis indicated that exposure to the 0.3T and 0.7T fields showed no change and that exposure to the 6.34T field showed an increase in the percentage of G1 phase cells. Our conclusions were as follows: 1) magnetic fields decreased the colony-forming abilities of cultured mammalian cells; 2) magnetic fields can affect the cell cycle; 3) a stronger magnetic field strength does not always have stronger biological effects and 4) the gradient of a magnetic field may be an important factor when combined with ionizing radiation. Despite the foregoing analysis, the biological effects of magnetic fields on mammalian cells remains a complex phenomena.
journal_name
Nagoya J Med Scijournal_title
Nagoya journal of medical scienceauthors
Zhang XR,Kobayashi H,Hayakawa A,Ishigaki Tsubject
Has Abstractpub_date
1995-12-01 00:00:00pages
157-64issue
3-4eissn
0027-7622issn
2186-3326journal_volume
58pub_type
杂志文章abstract：:A new hypothesis for the origin of metastases is presented. It assumes that a cancer-transformed gene in a primary tumour is incorporated in its identical form via a virus-vector function into biologically potent recipient cells in other organs, such as stem cells, multipotent cells or cells in an early phase of divis...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2013-02-01 00:00:00
abstract：:Being homebound has been reported to be associated with a number of conditions. In the current study, the incidence of homebound individuals was surveyed in an urban city area in Japan. The city office randomly enrolled 5,000 residents of Nagoya City aged 65 and over. A questionnaire was sent to their principal caregi...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2015-08-01 00:00:00
abstract：:Binding of epidermal growth factor (EGF) to its receptor was evaluated in the four cultured choriocarcinoma cell lines BeWo, NaUCC-1, NaUCC-2, and NaUCC-3. Also, the effect of the anti-tumor drugs actinomycin-D (Act-D) and methotrexate (MTX) on the EGF receptor binding was investigated in these cell lines. Incubation ...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：1990-03-01 00:00:00
abstract：:Proteinuria is an established risk factor for diabetic nephropathy. Recent studies indicate that some xanthine oxidase inhibitors have a renoprotective effect. The aim of this study was to assess whether topiroxostat reduces albuminuria in hyperuricemic patients with diabetic nephropathy and overt proteinuria. The ETU...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2016-05-01 00:00:00
abstract：:Thoracoscopic lobectomy has recently become a widely used surgical treatment for congenital cystic lung disease, but significant issues can arise in some cases, such as a limited working space in neonates, a limited view in cases involving large cystic lesions. We reviewed the treatment outcomes of neonates that under...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：10.18999/nagjms.78.4.447
更新日期：2016-12-01 00:00:00
abstract：:In endovascular coil embolization for intracranial aneurysms, as coils are filled in the aneurysm and the stage of procedure is advanced, the force to push forward the coil delivery wire (insertion force) increases. However, the coil insertion force that interventionist's felt at his fingertips does not directly refle...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：10.18999/nagjms.81.2.217
更新日期：2019-05-01 00:00:00
abstract：:The catalytic subunit of human DNA polymerase (pol) delta, p125, was expressed in recombinant baculovirus-infected insect cells, separated from a baculovirus-encoded DNA polymerase, and was purified to homogeneity by affinity trapping with a histidine-octapeptide at the C-terminus of p125 as the ligand. Purified p125 ...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2000-11-01 00:00:00
abstract：:The influence of total ischemia on the formation of products of anaerobic metabolism was investigated in canine hearts in vitro. Contents of organic acids were quantitatively analyzed by gas chromatography-mass spectrometry, and high energy phosphate compounds were determined using the luciferin-luciferase enzyme syst...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章,评审
doi：
更新日期：1994-03-01 00:00:00
abstract：:The purpose of this study was to demonstrate the characteristics of the Instrumental Activities of Daily Living (IADL) ability, evaluated by the Assessment of Motor and Process Skills (AMPS), and everyday memory functions (the memory necessary for daily life), assessed by the Rivermead Behavioral Memory Test (RBMT) in...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2007-01-01 00:00:00
abstract：:A 67-year-old man underwent posterior cervical decompression surgery for ossification of the posterior longitudinal ligament (OPLL) with fixation using cervical pedicle screws (CPSs) guided by intraoperative 3D image-based navigation. Intraoperatively, while creating the screw hole using the navigation probe, the virt...
journal_title：Nagoya journal of medical science
pub_type：
doi：10.18999/nagjms.82.4.799
更新日期：2020-11-01 00:00:00
abstract：:Vietnam is facing a problem of over-crowding in public hospitals. Long waiting time is a major dissatisfaction for patients. Reducing waiting time benefits not only patients but also hospitals in decreasing overall workload. To identify factors contributing to long waiting time in outpatient clinics, a cross-sectional...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：10.18999/nagjms.80.2.227
更新日期：2018-05-01 00:00:00
abstract：:Curved intertrochanteric varus osteotomy (CVO) is one of the good surgical procedures for avascular necrosis of the femoral head (ANFH) patients. However, some patients with failed CVO are converted to total hip arthroplasty (THA) as a salvage operation. We compared the clinical and radiographic outcomes of 10 hips co...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2016-02-01 00:00:00
abstract：:The Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study) is a long-term cohort study to investigate the interactions among genotypes, lifestyles, and lifestyle-related diseases, especially cancer. This article reports the outline of the baseline survey of the Daiko Study, one site of the J-MICC Study. T...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2011-08-01 00:00:00
abstract：:Disorientation responses of animals exposed to microgravity produced by parabolic aircraft flights and also in-space experiments were reviewed. Disoriented postures in floating are largely species-dependent. Reflexive lowered tone of gravity-bearing extensor muscles by labyrinthectomy is not seen in mammals (hamster a...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：:Accessibility to health care services in Thailand is generally good, but a few areas in the country are difficult to reach. The purpose of this study was to investigate the accessibility of health care services in rural and remote areas of Thailand. It was conducted in 16 remote villages within a catchment area with a...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2013-08-01 00:00:00
abstract：:The distribution of nerve fibers containing either calcitonin gene-related peptide (CGRP) and substance P (SP) was investigated in rat skin with special reference to their relationship to the lymphatic vessels. These nerve fibers exhibited a similar distribution pattern but the former were more numerous than the latte...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：1996-12-01 00:00:00
abstract：:The cutoff values of fractional flow reserve (FFR) to detect physiological myocardial ischemia are still controversial. Some studies have reported that left ventricular (LV) dyssynchrony occurs in patients with coronary artery disease (CAD). The purpose of this study was to investigate LV dyssynchrony in patients with...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2015-02-01 00:00:00
abstract：:The survey involves examining the applications from 142 institutions that have consented to make available all certification applications from 2015 and 2016 to a research project for building a certification system for an ethics committee run by the Agency for Medical Research and Development. The number of certified ...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：10.18999/nagjms.81.3.501
更新日期：2019-08-01 00:00:00
abstract：:Little is known about the carbohydrate structure of the platelet von Willebrand factor (vWf). We have analyzed N-linked oligosaccharides from both plasma and platelet vWf by Fluorophore-Assisted-Carbohydrate Electrophoresis (FACE) and isoelectric focusing before and after digestion of the proteins with neuraminidase. ...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2000-05-01 00:00:00
abstract：:The Japanese Orthopaedic Association has proposed the term "locomotive syndrome" to designate a condition that places a person at high risk for long-term care. However, in daily clinical practice, even when a diagnosis of locomotive syndrome is made, exercise therapy often cannot be successfully performed in some pati...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：10.18999/nagjms.79.1.43
更新日期：2017-02-01 00:00:00
abstract：:Syntrophins are the cytoplasmic peripheral proteins of dystrophin glycoprotein complex, of which five (alpha l, beta 1, beta 2, gamma 1 and gamma 2) isoforms have been identified so far. Respective syntrophin isoforms are encoded by different genes but have similar domain structures. At the sarcolemma of skeletal musc...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2008-08-01 00:00:00
abstract：:Since smoking is implicated in many diseases, medical professionals are expected to contribute to the reduction of smoking rates in their practice. Medical students are also expected to learn the importance of practical measures against smoking. This study surveyed the smoking rates and attitudes to smoking among medi...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2010-08-01 00:00:00
abstract：:A study was conducted to clarify the prognostic factors related to recurrence of craniopharyngioma and to improve the quality of life of patients by the treatment with intentional partial removal and gamma knife radiosurgery. One hundred cases of craniopharyngioma have been treated at Komaki City Hospital since 1991. ...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2012-02-01 00:00:00
abstract：:Umbilical metastasis from intra-abdominal or pelvic malignancy, which is called Sister Mary Joseph's nodule (SMJN), is rare, and it has a poor prognosis. Its most common primary sites are the stomach and ovaries. SMJN caused by colon cancer is uncommon. A 42-year-old woman visited local clinics with complaints of an u...
journal_title：Nagoya journal of medical science
pub_type：
doi：10.18999/nagjms.81.2.325
更新日期：2019-05-01 00:00:00
abstract：:Meningiomas are common spinal tumor and mostly located at intradura. Recurrence rate after surgery for extradural meningioma was higher than intradural meningioma. A patient with intra and extradural spinal meningioma was treated and discussed its features and clinical management. A 41-year-old woman noted numbness of...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：10.18999/nagjms.79.1.115
更新日期：2017-02-01 00:00:00
abstract：:The aim of this study was to identify the socio-demographic characteristics, knowledge, attitude and accessibility factors related to the utilization of antenatal care (ANC) service among pregnant women in the Kham District, Laos. Data for this cross-sectional study were collected in July 2008, using a two-stage clust...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2010-02-01 00:00:00
abstract：:Surgical intervention for the treatment of acetabular fracture non-union is often challenging. Here, we present a case of acetabular fracture non-union with pelvic discontinuity in a patient who underwent cemented total hip arthroplasty (THA) after intra- and extra-articular plate fixation. The case was a 70-year-old ...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：10.18999/nagjms.81.1.113
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Copper toxicity steadily affects the livers of patients with Wilson disease. However, the toxic effect of copper on serum aspartate and alanine aminotransferase levels remains to be clarified as a prerequisite for diagnostic tests. The clinical records of 33 cases were analyzed to clarify the natural history...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2014-02-01 00:00:00
abstract：:In the present study, we developed quantitative index for evaluating regional liver function using 99mTc diethylenetriamine-pentaacetic acid galactosyl human serum albumin (GSA). A three head SPECT equipped with a low energy high resolution parallel hole collimator was used. Used pre-filter was Butterworth and axial i...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章
doi：
更新日期：2003-05-01 00:00:00
abstract：:Dialysis-induced hypotension, the sharp decrease in blood pressure occurring during hemodialysis, remains one of the most difficult problems associated with hemodialysis even today. However, there is yet no established theory to explain the mechanism triggering dialysis-induced hypotension. This review attempts to off...
journal_title：Nagoya journal of medical science
pub_type： 杂志文章,评审
doi：
更新日期：1992-03-01 00:00:00
