Long term follow up of severely ill patients who underwent urgent cardiac transplantation.

Abstract:

OBJECTIVE:To assess long term survival (> 5 years) and quality of life in severely ill patients referred for urgent cardiac transplantation. SETTING:Tertiary referral centres: before transplantation at the National Heart Hospital (late 1984 to end 1986); after transplantation at Harefield Hospital. SUBJECTS:Eighteen patients (15 men; three women) who had required intensive support in hospital before cardiac transplantation and were alive at short term follow up. INTERVENTIONS:Intravenous infusions of cardiac drugs (mean 2.2 infusions), intravenous diuretics (17 patients), and many other drugs before transplantation. Intra-aortic balloon counterpulsation (four patients), temporary pacing (two), and resuscitation from cardiac arrest (three). Patients had specialised nursing care on a medical intensive care unit in almost every case. MAIN OUTCOME MEASURES:Long term survival in patients after urgent cardiac transplantation and perceived quality of life. RESULTS:Of 18 patients who were alive at short term follow up (mean (range) 19.4 (10-33) months), 14 were still alive in 1992 (69 (61-83) months). Ten still worked full time, and 11 reported no restrictions in their daily activities. Three of four patients who died in the intervening period survived > 5 years after transplantation. Overall, 17 of 18 patients survived at least 5 years. CONCLUSIONS:In severely ill patients who undergo urgent cardiac transplantation and survive in the short term, long term (5-7 year) survival and quality of life seem good.

journal_name

BMJ

authors

Mulcahy D,Fitzgerald M,Wright C,Sparrow J,Pepper J,Yacoub M,Fox KM

doi

10.1136/bmj.306.6870.98

subject

Has Abstract

pub_date

1993-01-09 00:00:00

pages

98-101

issue

6870

eissn

0959-8138

issn

1756-1833

journal_volume

306

pub_type

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